GENE:RTEL1
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | RTEL1 |
FullNmae | regulator of telomere elongation helicase 1 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:15888 |
EnsembleID | ENSG00000258366 |
Uniprot | Q9NZ71 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
RTEL1 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
RTEL1 | cuproptosis | 38495196 | Cuproptosis-related genes were manually curated, and differentially expressed cuproptosis-related genes (DECuGs) were identified.Then, the 16 DECuGs were obtained by the intersection of the 5018 DEGs and 63 cuproptosis-related genes. | 63 cuproptosis-related genes |
RTEL1 | cuproptosis | 36685880 | A total of 43 CRGs were manually identified and used to investigate the effects of cuproptosis in HNSC in current study. | cuproptosis-related genes |
Go Annotation:
GeneSymbol | Go id |
---|---|
RTEL1 | GO:0000723,GO:0000723,GO:0000732,GO:0000732,GO:0000781,GO:0003677,GO:0003678,GO:0003678,GO:0003678,GO:0003678,GO:0005515,GO:0005524,GO:0005524,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0006281,GO:0010569,GO:0010569,GO:0016607,GO:0016887,GO:0031297,GO:0031965,GO:0032206,GO:0032508,GO:0032508,GO:0043247,GO:0045910,GO:0045910,GO:0046872,GO:0051539,GO:0070182,GO:0090657,GO:0090657,GO:0090657,GO:1902990,GO:1904355,GO:1904358,GO:1904430,GO:1904430,GO:1904430,GO:1904430,GO:1904506,GO:1904535 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | RTEL1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
E2F4 | RTEL1 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | RTEL1 | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
YBX1 | RTEL1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
CIAO1 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
ZNRD2 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
CIAO2B | RTEL1 | 24234451 25348397 28178521 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TUBB | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
VAV2 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
NCK1 | RTEL1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
UBXN11 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
SKAP1 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
CUL3 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
PPM1A | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
XRCC5 | RTEL1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
RPA1 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
LRP1 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
HNRNPL | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
RAD51 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
RPA2 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
RPA3 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
AATF | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
THBS3 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
MMS19 | RTEL1 | 24234451 25348397 28178521 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
LIMK1 | RTEL1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
EMSY | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
PDCD1 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
PSME3 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
EFNB3 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
KATNA1 | RTEL1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
NDUFA13 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
ARL15 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
GATD1 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
THAP11 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
RIPK4 | RTEL1 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
THBS4 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
SASS6 | RTEL1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
INTS14 | RTEL1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
ANKLE2 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
ATP13A2 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
NCAPH2 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
GAS2L1 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
WDFY3 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
RTEL1 | CBWD1 | 25348397 | N/A | physical interaction | ComPPI |
RTEL1 | ISLR | 25348397 | N/A | physical interaction | ComPPI |
RTEL1 | LIPH | 25348397 | N/A | physical interaction | ComPPI |
RTEL1 | FAM13A | 25348397 | N/A | physical interaction | ComPPI |
RTEL1 | PRSS21 | 25348397 | N/A | physical interaction | ComPPI |
RTEL1 | SS18L2 | 25348397 | N/A | physical interaction | ComPPI |
RTEL1 | CCNYL1 | 25348397 | N/A | physical interaction | ComPPI |
RTEL1 | VWA5A | 25348397 | N/A | physical interaction | ComPPI |
RTEL1 | SLC18A1 | 25348397 | N/A | physical interaction | ComPPI |
NEUROG3 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |