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GENE：TRADD

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TRADD
FullNmae TNFRSF1A associated via death domain
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12030
EnsembleID ENSG00000102871
Uniprot Q15628

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TRADD necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TRADD necroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
TRADD autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TRADD apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TRADD apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TRADD GO:0002947,GO:0002947,GO:0005068,GO:0005068,GO:0005164,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0005856,GO:0005886,GO:0006915,GO:0007165,GO:0007169,GO:0008625,GO:0009898,GO:0019900,GO:0030335,GO:0031264,GO:0033209,GO:0033209,GO:0042802,GO:0043065,GO:0043123,GO:0043235,GO:0044877,GO:0050729,GO:0051092,GO:0051092,GO:0051798,GO:0060090,GO:0070513,GO:0071356,GO:0097191,GO:0097191,GO:0097191,GO:1901224

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TRADD hsa:8717 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
TRADD hsa:8717 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)
TRADD hsa:8717 path:hsa04071 Sphingolipid signaling pathway - Homo sapiens (human)
TRADD hsa:8717 path:hsa04210 Apoptosis - Homo sapiens (human)
TRADD hsa:8717 path:hsa04217 Necroptosis - Homo sapiens (human)
TRADD hsa:8717 path:hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human)
TRADD hsa:8717 path:hsa04657 IL-17 signaling pathway - Homo sapiens (human)
TRADD hsa:8717 path:hsa04668 TNF signaling pathway - Homo sapiens (human)
TRADD hsa:8717 path:hsa04920 Adipocytokine signaling pathway - Homo sapiens (human)
TRADD hsa:8717 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
TRADD hsa:8717 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
TRADD hsa:8717 path:hsa05131 Shigellosis - Homo sapiens (human)
TRADD hsa:8717 path:hsa05132 Salmonella infection - Homo sapiens (human)
TRADD hsa:8717 path:hsa05152 Tuberculosis - Homo sapiens (human)
TRADD hsa:8717 path:hsa05160 Hepatitis C - Homo sapiens (human)
TRADD hsa:8717 path:hsa05162 Measles - Homo sapiens (human)
TRADD hsa:8717 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
TRADD hsa:8717 path:hsa05164 Influenza A - Homo sapiens (human)
TRADD hsa:8717 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
TRADD hsa:8717 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
TRADD hsa:8717 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
TRADD hsa:8717 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
TRADD hsa:8717 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
TRADD hsa:8717 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FADD TRADD 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21183682 21232017 21411734 21826665 22955274 23010170 23170255 23180781 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 8910423 9488730 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
RIPK1 TRADD 10465784 10734135 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 12887920 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 16713974 17301840 17462996 17496911 17560373 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19632174 19641494 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 28765050 8910423 8974401 9379049 9488730 9582321 interaction type N/A ACSN
TNF TRADD 10925299 11003656 11112697 11274345 11279185 11280761 11438547 11460167 11875494 12531547 12646658 12811837 12887920 1330325 1431106 14607933 14625680 14660645 14730360 15099563 15310755 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 21920725 22955274 23010170 23170255 23180781 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26801188 26972597 28574505 28765050 8663014 8910423 9488730 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
TRAF2 TRADD 10465784 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15592525 15699106 16713974 17301840 17462996 17496911 17916596 18264787 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 28765050 8910423 9379049 9488730 9582321 interaction type N/A ACSN
TRADD TNFRSF1A 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26192618 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321 interaction type N/A ACSN
TRADD MAP3K1 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26192618 26587781 26653790 28574505 28765050 9379049 9582321 interaction type N/A ACSN
TRADD MAP3K5 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26192618 26587781 26653790 28574505 28765050 interaction type N/A ACSN
TRADD IKBKG 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 8910423 9488730 interaction type N/A ACSN
TRADD MAP3K7 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 8910423 9488730 interaction type N/A ACSN
TRADD TAB2 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 8910423 9488730 interaction type N/A ACSN
TRADD TAB3 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 8910423 9488730 interaction type N/A ACSN
TRADD DAB2IP 10734135 15310755 18292600 23180781 26192618 8974401 association,physical association anti tag coimmunoprecipitation ACSN,InnateDB
TRADD RFK 10734135 11274345 12887920 14730360 15310755 17560373 18292600 18641653 19641494 21232017 23010170 26192618 8974401 interaction type N/A ACSN
TRADD MAP2K4 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26192618 26587781 26653790 28574505 28765050 interaction type N/A ACSN
TRADD MAP2K3 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26192618 26587781 26653790 28574505 28765050 interaction type N/A ACSN
TRADD MAP2K7 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26192618 26587781 26653790 28574505 28765050 interaction type N/A ACSN
TRADD MAP2K6 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26192618 26587781 26653790 28574505 28765050 interaction type N/A ACSN
SQSTM1 TRADD 10356400 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRADD TRPC4AP 14585990 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
TRADD MAVS 18439848 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRADD TRAF1 18439848 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRAF3 TRADD 18439848 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRADD FADD 11464215 21183682 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
TRADD RIPK1 16603398 23180781 physical association anti tag coimmunoprecipitation InnateDB
TNFRSF1A TRADD 10795740 12721308 15115707 15173123 15310755 15357952 15465831 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
TRADD OPTN 17702576 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRADD SH3KBP1 15707590 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRADD TNF 12887920 19287455 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
TRADD CASP8 15173123 17047155 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRADD TRAF2 11479302 18439848 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRADD TANK 21419663 23180781 physical association anti tag coimmunoprecipitation InnateDB
CASP8 TRADD 22421964 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKG TRADD 17702576 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRADD TRADD 14585074 18545270 26467481 8565075 8612133 8702708 bind,up-regulates activity N/A Signor

Source Target Pmid Interactiontype Methods Database
TRADD TNFRSF10A 20005715 interaction type N/A PSP
TRADD TNFRSF10B 20005715 interaction type N/A PSP
TRADD AIFM1 20005715 interaction type N/A PSP
TRADD NGFR 20005715 interaction type N/A PSP
TRADD ATP2A2 20005715 interaction type N/A PSP
TRADD DAPK1 20005715 interaction type N/A PSP
TRADD BIRC3 20005715 interaction type N/A PSP
TRADD RIPK1 18988627 20005715 21071413 8612133 interaction type N/A PSP,SignaLink
TRADD CASP8 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
FOXP3 TRADD 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 TRADD 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 TRADD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TRADD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TRADD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TRADD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 TRADD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 TRADD N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000254A6 TRADD 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 TRADD 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE TRADD 25416803 25732226 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
TRADD CASP8 25361965 interaction type N/A PTMCode2
CASP8 TRADD 25361965 interaction type N/A PTMCode2
TRADD TNF 25361965 interaction type N/A PTMCode2
TNF TRADD 25361965 interaction type N/A PTMCode2
NGFR TRADD 25361965 interaction type N/A PTMCode2
TRADD NGFR 25361965 interaction type N/A PTMCode2
CAV1 TRADD 25361965 interaction type N/A PTMCode2
TRADD CAV1 25361965 interaction type N/A PTMCode2
BCL10 TRADD 25361965 interaction type N/A PTMCode2
TRADD BCL10 25361965 interaction type N/A PTMCode2
HIPK2 TRADD 25361965 interaction type N/A PTMCode2
TRADD HIPK2 25361965 interaction type N/A PTMCode2
TRPC4AP TRADD 25361965 interaction type N/A PTMCode2
TRADD TRPC4AP 25361965 interaction type N/A PTMCode2
FADD TRADD 25361965 interaction type N/A PTMCode2
TRADD FADD 25361965 interaction type N/A PTMCode2
RIPK1 TRADD 25361965 interaction type N/A PTMCode2
TRADD RIPK1 25361965 interaction type N/A PTMCode2
TNFRSF10A TRADD 25361965 interaction type N/A PTMCode2
TRADD TNFRSF10A 25361965 interaction type N/A PTMCode2
TNFRSF21 TRADD 25361965 interaction type N/A PTMCode2
TRADD TNFRSF21 25361965 interaction type N/A PTMCode2
TNFRSF1A TRADD 25361965 interaction type N/A PTMCode2
TRADD TNFRSF1A 25361965 interaction type N/A PTMCode2
BIRC2 TRADD 25361965 interaction type N/A PTMCode2
TRADD BIRC2 25361965 interaction type N/A PTMCode2
PSMC3 TRADD 25361965 interaction type N/A PTMCode2
TRADD PSMC3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KRT18 TRADD 11684708 14525934 24234451 25348397 colocalization,physical association two hybrid,coimmunoprecipitation,cosedimentation,experimental interaction detection,physical interaction,fluorescence microscopy,in vitro,in vivo ComPPI,HPRD,IntAct
MAD2L2 TRADD 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
HSPA8 TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
IFIT3 TRADD 25348397 N/A physical interaction ComPPI
SH3KBP1 TRADD 25348397 N/A physical interaction ComPPI
VIM TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
ACTG1 TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PPP2R1A TRADD 14525934 17540176 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
STAT1 TRADD 10848577 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TUBB TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRAF6 TRADD 25348397 N/A physical interaction ComPPI
CALM1 TRADD 25348397 N/A tandem affinity purification ComPPI
OPTN TRADD 25348397 N/A physical interaction ComPPI
SLC25A6 TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
HSP90AB1 TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PRKDC TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
KPNB1 TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CDKN2A TRADD 25348397 N/A physical interaction ComPPI
UBB TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
HSP90AA1 TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CAV1 TRADD 25348397 N/A physical interaction ComPPI
CASP8 TRADD 12887920 17047155 19524513 24234451 25348397 30561431 association anti bait coimmunoprecipitation,physical interaction,virotrap ComPPI,IntAct
TRAF3 TRADD 14525934 24234451 25348397 30561431 8565075 association,physical association two hybrid,experimental interaction detection,in vivo,two hybrid,virotrap ComPPI,HPRD,IntAct
TNFRSF1A TRADD 11684708 11934887 14525934 16611992 19524513 19641494 19781631 23955153 24234451 25348397 7758105 8565075 8612133 8621670 8943045 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
C1QBP TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TNFRSF25 TRADD 14525934 25348397 8934525 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
CAD TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PDLIM7 TRADD 25348397 N/A physical interaction ComPPI
FADD TRADD 10911999 11112409 14525934 23955153 24234451 25348397 30561431 8565075 8681376 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach,two hybrid,virotrap ComPPI,HPRD,IntAct
TNF TRADD 12887920 21822306 23955153 24234451 25348397 30561431 association anti tag coimmunoprecipitation,pull down,physical interaction,virotrap ComPPI,IntAct
XPO1 TRADD 25348397 N/A physical interaction ComPPI
TRAF1 TRADD 14525934 24234451 25348397 8565075 physical association two hybrid,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
TRAF2 TRADD 10892748 14525934 14743216 23955153 24234451 25348397 30561431 8565075 8702708 9020361 association,physical association anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,x-ray crystallography,physical interaction,two hybrid array,in vitro,in vivo,tandem affinity purification,two hybrid prey pooling approach,two hybrid,virotrap ComPPI,HPRD,IntAct
CLTC TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
IPO7 TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
IPO8 TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
ATP1A1 TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
NGFR TRADD 12604596 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HIPK2 TRADD 11032752 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
CHUK TRADD 25348397 N/A physical interaction ComPPI
RIPK1 TRADD 14525934 24234451 25348397 30561431 8612133 association,physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,virotrap ComPPI,HPRD,IntAct
TRPC4AP TRADD 14525934 14585990 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TNFRSF1B TRADD 25348397 N/A physical interaction ComPPI
CYBA TRADD 19641494 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP2A2 TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
EDAR TRADD 25348397 N/A physical interaction ComPPI
TRADD BIRC2 14525934 24234451 25348397 30561431 8943045 association experimental interaction detection,in vivo,virotrap ComPPI,HPRD,IntAct
TRADD TNFRSF10A 14525934 25348397 9430227 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TRADD TNFRSF10B 14525934 25348397 9430227 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TRADD CNTRL 10187805 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TRADD TNFRSF21 14525934 24234451 24374337 25348397 9714541 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
TRADD FAS 11032752 14525934 17692826 25348397 27898060 8681376 9427646 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
TRADD KRT14 11684708 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
TRADD USP2 25348397 N/A physical interaction ComPPI
TRADD TRIP12 25348397 N/A physical interaction ComPPI
TRADD CDKN2A 25348397 N/A physical interaction ComPPI
TRADD DAB2IP 25348397 N/A physical interaction ComPPI
TRADD LRRK2 19176810 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRADD TOMM70 25348397 N/A physical interaction ComPPI
TRADD ZMYND11 25348397 N/A physical interaction ComPPI
TRADD NEDD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRADD BPNT1 25348397 N/A physical interaction ComPPI
TRADD AIFM1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD HSPA1L 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD SLC25A5 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD RPS3 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD DNAJA1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD SLC25A3 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD LGALS3BP 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD NAP1L1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD RCN2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD CCAR2 14743216 24234451 25348397 30561431 association,physical association tandem affinity purification,virotrap ComPPI,IntAct
TRADD ATAD3A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD RPS16 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD RPS27 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
BCL10 TRADD 10400625 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
EEF1A2 TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD DAPK1 12911633 14525934 N/A experimental interaction detection HPRD
TRADD TRADD 11684708 14525934 14743216 24234451 30561431 7758105 8621670 association,physical association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,tandem affinity purification,virotrap HPRD,IntAct
CALM2 TRADD 14743216 24234451 physical association tandem affinity purification IntAct
TRADD S1PR2 24234451 30561431 association virotrap IntAct
TRADD RFC3 24234451 30561431 association virotrap IntAct
TRADD RCC2 24234451 30561431 association virotrap IntAct
TRADD RANBP2 24234451 30561431 association virotrap IntAct
TRADD PLOD1 24234451 30561431 association virotrap IntAct
TRADD PKN2 24234451 30561431 association virotrap IntAct
TRADD PDPN 24234451 30561431 association virotrap IntAct
TRADD OGN 24234451 30561431 association virotrap IntAct
TRADD NLGN1 24234451 30561431 association virotrap IntAct
TRADD HERC4 24234451 30561431 association virotrap IntAct
TRADD UBE2V2 24234451 30561431 association virotrap IntAct
TRADD THOC2 24234451 30561431 association virotrap IntAct
TRADD SRP19 24234451 30561431 association virotrap IntAct
TRADD CHPF 24234451 30561431 association virotrap IntAct
TRADD ANTXR1 24234451 30561431 association virotrap IntAct
TRADD AKR7A2 24234451 30561431 association virotrap IntAct
TRADD UEVLD 24234451 30561431 association virotrap IntAct
TRADD TNIP1 24234451 30561431 association virotrap IntAct
TRADD TNFAIP3 24234451 30561431 association virotrap IntAct
TRADD TENM3 24234451 30561431 association virotrap IntAct
TRADD NUP85 24234451 30561431 association virotrap IntAct
TRADD KLKB1 24234451 30561431 association virotrap IntAct
TRADD HNRNPCL2 24234451 30561431 association virotrap IntAct
TRADD HAPLN3 24234451 30561431 association virotrap IntAct
TRADD G3BP1 24234451 30561431 association virotrap IntAct
TRADD DUS3L 24234451 30561431 association virotrap IntAct
TRADD DRG1 24234451 30561431 association virotrap IntAct
TRADD COASY 24234451 30561431 association virotrap IntAct
TRADD MINDY3 24234451 30561431 association virotrap IntAct
TRADD EIF3C 24234451 30561431 association virotrap IntAct
TRADD DENND5A 24234451 30561431 association virotrap IntAct
TRADD ULK3 24234451 30561431 association virotrap IntAct
TRADD RRP9 24234451 30561431 association virotrap IntAct
TRADD RNF115 24234451 30561431 association virotrap IntAct
TRADD PRPF4 24234451 30561431 association virotrap IntAct
TRADD POLR1A 24234451 30561431 association virotrap IntAct
TRADD PCSK5 24234451 30561431 association virotrap IntAct
TRADD PCOLCE2 24234451 30561431 association virotrap IntAct
TRADD NOL6 24234451 30561431 association virotrap IntAct
TRADD IKBKG 24234451 30561431 association virotrap IntAct
TRADD THAP4 24234451 30561431 association virotrap IntAct
TRADD RBP4 24234451 30561431 association virotrap IntAct
TRADD CHST12 24234451 30561431 association virotrap IntAct
TRADD C1QTNF3 24234451 30561431 association virotrap IntAct
TRADD AFM 24234451 30561431 association virotrap IntAct
TNFAIP3 TRADD 12654725 27898060 inhibition,stimulant N/A OmniPath
TRAF2 TRADD 10892748 10911999 11181075 11479302 12796506 14585074 14743216 18439848 19815541 23955153 27898060 8565075 8702708 9020361 N/A N/A OmniPath
TRADD TRAF2 10892748 10911999 11181075 11479302 12796506 14585074 14743216 18439848 19815541 23955153 27898060 8565075 8702708 9020361 inhibition,stimulant N/A OmniPath
TRADD FADD 10521396 10911999 11112409 11464214 11464215 12107169 12796506 12911633 14744432 16006552 16919273 18545270 21183682 21724995 21760970 23955153 24686082 27898060 8565075 8642271 8681376 9430228 stimulant N/A OmniPath
TNFRSF10B TRADD 27898060 9430227 9430228 stimulant N/A OmniPath
TRADD MAVS 18439848 27898060 N/A N/A OmniPath
CASP8 TRADD 12887920 14585074 15173123 17047155 18776134 22421964 27898060 N/A N/A OmniPath
TRADD CASP8 12887920 14585074 15173123 17047155 18776134 22421964 27898060 stimulant N/A OmniPath
TNF TRADD 12753742 12887920 15485837 16603398 19287455 20005846 22099304 23732909 24980434 27898060 inhibition N/A OmniPath
TRADD BIRC2 27898060 8943045 stimulant N/A OmniPath
KRT18 TRADD 11684708 27898060 inhibition N/A OmniPath
RIPK1 TRADD 12441346 16603398 18545270 21724995 24735611 27898060 8612133 stimulant N/A OmniPath
TRADD RIPK1 12441346 16603398 18545270 21724995 24735611 27898060 8612133 stimulant N/A OmniPath
TNFRSF1A TRADD 10187805 10358032 10463949 10634209 10795740 11002422 11035039 11231290 11502070 11684708 11821416 11934887 12167698 12721308 12786973 12887920 15115707 15173123 15310755 15357952 15465831 15725726 16006552 16611992 16798936 16919273 18776134 18939944 19641494 21232017 21724995 21741934 21760970 22297296 23955153 24130170 24758719 27898060 7758105 8565075 8612133 8621670 8642271 8791485 8875942 8943045 9082980 9129204 9430227 9915703 9916731 stimulant N/A OmniPath
TRADD TNFRSF1A 10187805 10358032 10463949 10634209 10795740 11002422 11035039 11231290 11684708 11821416 11934887 12167698 12721308 12786973 12887920 15115707 15173123 15310755 15357952 15465831 15725726 16006552 16611992 16798936 16919273 18776134 18939944 19641494 21232017 21724995 21741934 21760970 22297296 23955153 24130170 24758719 27898060 7758105 8565075 8612133 8621670 8642271 8791485 8875942 8943045 9082980 9129204 9430227 9915703 9916731 inhibition,stimulant N/A OmniPath
TRAF3 TRADD 18439848 27898060 8565075 N/A N/A OmniPath
TNFRSF10A TRADD 27898060 9430227 9430228 stimulant N/A OmniPath
TANK TRADD 21419663 27898060 N/A N/A OmniPath
TRAF1 TRADD 18439848 19287455 27898060 8565075 N/A N/A OmniPath
TRADD TRAF1 10629108 18439848 19287455 27898060 8565075 stimulant N/A OmniPath
TRADD TRPC4AP 14585990 27898060 N/A N/A OmniPath
TRPC4AP TRADD 14585990 27898060 N/A N/A OmniPath
TRADD DAB2IP 15310755 27898060 N/A N/A OmniPath
OPTN TRADD 17702576 27898060 N/A N/A OmniPath
TRADD TRAF5 19632174 27898060 stimulant N/A OmniPath
TNFRSF21 TRADD 14585074 24374337 27898060 9714541 stimulant N/A OmniPath
TNFRSF25 TRADD 14585074 21421854 27898060 8875942 8934525 9430227 9714541 stimulant N/A OmniPath
KRT14 TRADD 11684708 27898060 inhibition N/A OmniPath

Visualization










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