Gene Information gene info

GENE:SCAP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SCAP
FullNmae SREBF chaperone
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30634
EnsembleID ENSG00000114650
Uniprot Q12770

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SCAP cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
SCAP GO:0000139,GO:0000139,GO:0001666,GO:0005515,GO:0005783,GO:0005789,GO:0005789,GO:0005794,GO:0006955,GO:0008203,GO:0012507,GO:0016020,GO:0032868,GO:0032933,GO:0032933,GO:0032934,GO:0032936,GO:0042304,GO:0044255,GO:0044877,GO:0045540,GO:0045541,GO:0045542,GO:0051082,GO:0090110

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 SCAP 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SCAP 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 SCAP 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 SCAP 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SCAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SCAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SCAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SCAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SCAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SCAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SCAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SCAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SCAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000DDD35 SCAP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE SCAP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 SCAP 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SCAP INSIG1 25361965 interaction type N/A PTMCode2
INSIG1 SCAP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
INSIG2 SCAP 12242332 12482938 14525934 16549805 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
SREBF1 SCAP 25348397 N/A physical interaction ComPPI
SREBF2 SCAP 10896675 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
VCAM1 SCAP 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
RNF139 SCAP 25348397 N/A physical interaction ComPPI
SCAP INSIG1 12202038 12482938 12842885 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SCAP PGRMC1 14525934 15782218 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SCAP SEC24B 25348397 N/A physical interaction ComPPI
SCAP ERLIN2 25348397 N/A physical interaction ComPPI
SCAP MOV10 25348397 N/A physical interaction ComPPI
SCAP NXF1 25348397 N/A physical interaction ComPPI
SCAP MCOLN3 25348397 N/A physical interaction ComPPI
SCAP NAALADL2 25348397 N/A physical interaction ComPPI
SCAP HLA-C 25348397 N/A physical interaction ComPPI
SCAP ATP1B4 25348397 N/A physical interaction ComPPI
SCAP BTNL8 25348397 N/A physical interaction ComPPI
SCAP LPAR1 25348397 N/A physical interaction ComPPI
SCAP GLRA2 25348397 N/A physical interaction ComPPI
SCAP RPTOR 25348397 N/A physical interaction ComPPI
SCAP IPPK 25348397 N/A physical interaction ComPPI
SCAP ZNRF4 25348397 N/A physical interaction ComPPI
SCAP B4GAT1 25348397 N/A physical interaction ComPPI
SCAP NUDC 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
SCAP SCAP 14525934 15782218 N/A experimental interaction detection HPRD
AR SCAP 15133039 27898060 stimulant N/A OmniPath

Visualization