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GENE：SDHAF2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SDHAF2
FullNmae succinate dehydrogenase complex assembly factor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26034
EnsembleID ENSG00000167985
Uniprot Q9NX18

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SDHAF2 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
SDHAF2 GO:0005515,GO:0005730,GO:0005739,GO:0005739,GO:0005759,GO:0005829,GO:0006099,GO:0006121,GO:0006121,GO:0006470,GO:0010719,GO:0018293,GO:0018293,GO:0034553,GO:0090090

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SDHAF2 SDHA 19628817 26192618 interaction type N/A ACSN
SDHAF2 ELP1 16169070 23180781 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 SDHAF2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA SDHAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SDHAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SDHAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SDHAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003AA845 SDHAF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004C5774 SDHAF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB SDHAF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 SDHAF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE SDHAF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000047944F SDHAF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D SDHAF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003758F0 SDHAF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000453664 SDHAF2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 SDHAF2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000AB32B SDHAF2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 SDHAF2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000048BA36 SDHAF2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 SDHAF2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000049704B SDHAF2 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HSPA8 SDHAF2 25348397 N/A physical interaction ComPPI
SEC22A SDHAF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CPNE1 SDHAF2 25348397 N/A physical interaction ComPPI
PLAUR SDHAF2 25348397 N/A physical interaction ComPPI
EEF1A1 SDHAF2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
VCL SDHAF2 25348397 N/A physical interaction ComPPI
RRM2 SDHAF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUMO2 SDHAF2 25348397 N/A physical interaction ComPPI
CTTN SDHAF2 25348397 N/A physical interaction ComPPI
SSX2IP SDHAF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNB1 SDHAF2 25348397 N/A physical interaction ComPPI
HSPA9 SDHAF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CORO2A SDHAF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUCLG2 SDHAF2 25348397 N/A physical interaction ComPPI
PCMT1 SDHAF2 25348397 N/A physical interaction ComPPI
IMMT SDHAF2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TRIM25 SDHAF2 25348397 N/A physical interaction ComPPI
ELP1 SDHAF2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CTNNA2 SDHAF2 25348397 N/A physical interaction ComPPI
RBM12 SDHAF2 25348397 N/A physical interaction ComPPI
ABCA2 SDHAF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NOL8 SDHAF2 25348397 N/A physical interaction ComPPI
SDHAF2 CCDC90B 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SDHAF2 EEF1A1P5 25348397 N/A physical interaction ComPPI
SDHAF2 OXCT1 25348397 N/A physical interaction ComPPI
SDHAF2 COA7 25348397 N/A physical interaction ComPPI
SDHAF2 UQCRFS1 25348397 N/A physical interaction ComPPI
SDHAF2 UBXN7 25348397 N/A physical interaction ComPPI
SDHAF2 SH3BGRL 25348397 N/A physical interaction ComPPI
SDHAF2 SDHA 19628817 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SDHAF2 SLC1A5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SDHAF2 KLHDC2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SDHAF2 CWF19L2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SDHAF2 CYP4F2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SDHAF2 SDHB 19628817 23043141 27898060 stimulant N/A OmniPath

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