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GENE：SDSL

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SDSL
FullNmae serine dehydratase like
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30404
EnsembleID ENSG00000139410
Uniprot Q96GA7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SDSL cuproptosis 38367885 Cuproptosis score was lower in DCM and identified set of six CRGs (SEPTIN1, CLEC11A, ISG15, P3H3, SDSL, and INKA1) was positively associated with DCM and negatively correlated with cuproptosis score, which highlights the involvement of cuproptosis in DCM. cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
SDSL GO:0003674,GO:0003941,GO:0004794,GO:0005829,GO:0006565,GO:0006567,GO:0006629,GO:0008150,GO:0009097,GO:0030170,GO:0042802

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SDSL hsa:113675 path:hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human)
SDSL hsa:113675 path:hsa00270 Cysteine and methionine metabolism - Homo sapiens (human)
SDSL hsa:113675 path:hsa00290 Valine, leucine and isoleucine biosynthesis - Homo sapiens (human)
SDSL hsa:113675 path:hsa01100 Metabolic pathways - Homo sapiens (human)
SDSL hsa:113675 path:hsa01200 Carbon metabolism - Homo sapiens (human)
SDSL hsa:113675 path:hsa01230 Biosynthesis of amino acids - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 SDSL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SDSL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SDSL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SDSL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SDSL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SDSL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SDSL 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
SDSL TUBGCP4 14525934 16189514 19060904 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid ComPPI,HPRD,IntAct

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