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GENE：SERPIND1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SERPIND1
FullNmae serpin family D member 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4838
EnsembleID ENSG00000099937
Uniprot P05546

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SERPIND1 cuproptosis 36313444 Finally, seven copper death genes related to lung adenocarcinoma were screened out, including ARHGEF39, EFCC1, SERPIND1, INSL4, ANLN, RHOV and CCL20. copper death genes

Go Annotation:

GeneSymbol Go id
SERPIND1 GO:0004866,GO:0004867,GO:0005576,GO:0005576,GO:0005576,GO:0005615,GO:0005788,GO:0006935,GO:0007596,GO:0008201,GO:0010951,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SERPIND1 hsa:3053 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PITX3 SERPIND1 22278372 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP SERPIND1 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 SERPIND1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR2 SERPIND1 20034404 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SERPIND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SERPIND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SERPIND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SERPIND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SERPIND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SERPIND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SERPIND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SERPIND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 SERPIND1 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
SERPIND1 CTSG 25361965 interaction type N/A PTMCode2
CTSG SERPIND1 25361965 interaction type N/A PTMCode2
SERPIND1 F2 25361965 interaction type N/A PTMCode2
F2 SERPIND1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
IGHG1 SERPIND1 15174051 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
VAT1L SERPIND1 25348397 N/A physical interaction ComPPI
F2 SERPIND1 14525934 25348397 2760054 N/A experimental interaction detection,physical interaction ComPPI,HPRD
APP SERPIND1 25348397 N/A physical interaction ComPPI
TF SERPIND1 15174051 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SERPIND1 IGHA1 15174051 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CTSG SERPIND1 14525934 2318847 N/A experimental interaction detection HPRD
SERPIND1 SERPIND1 12169660 14525934 N/A experimental interaction detection HPRD
ELANE SERPIND1 14525934 2318847 N/A experimental interaction detection HPRD
ELANE SERPIND1 2318847 27898060 N/A N/A OmniPath

Visualization










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