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GENE：SHMT2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SHMT2
FullNmae serine hydroxymethyltransferase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10852
EnsembleID ENSG00000182199
Uniprot P34897

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SHMT2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SHMT2 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
SHMT2 GO:0000900,GO:0002082,GO:0002082,GO:0003682,GO:0004372,GO:0004372,GO:0004372,GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005737,GO:0005739,GO:0005743,GO:0005743,GO:0005743,GO:0005759,GO:0005759,GO:0005829,GO:0006544,GO:0006544,GO:0006563,GO:0006563,GO:0006565,GO:0006730,GO:0006730,GO:0008270,GO:0009113,GO:0015630,GO:0017148,GO:0019264,GO:0030170,GO:0030170,GO:0034340,GO:0034340,GO:0035999,GO:0035999,GO:0042645,GO:0042803,GO:0046653,GO:0046655,GO:0048027,GO:0051262,GO:0051289,GO:0051289,GO:0070062,GO:0070129,GO:0070536,GO:0070552,GO:0070552,GO:0070905,GO:1903715

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SHMT2 hsa:6472 path:hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human)
SHMT2 hsa:6472 path:hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human)
SHMT2 hsa:6472 path:hsa00670 One carbon pool by folate - Homo sapiens (human)
SHMT2 hsa:6472 path:hsa01100 Metabolic pathways - Homo sapiens (human)
SHMT2 hsa:6472 path:hsa01200 Carbon metabolism - Homo sapiens (human)
SHMT2 hsa:6472 path:hsa01230 Biosynthesis of amino acids - Homo sapiens (human)
SHMT2 hsa:6472 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)
SHMT2 hsa:6472 path:hsa01523 Antifolate resistance - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ADRB2 SHMT2 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 SHMT2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 SHMT2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP53 SHMT2 18922183 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CEBPA SHMT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SHMT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SHMT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SHMT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETV4 SHMT2 N/A trascriptional regulation,stimulation inferred by curator TFlink
SP1 SHMT2 N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A SHMT2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 SHMT2 21512034 rna interference,inhibition experimental interaction detection,miRNA interference luciferase reporter assay miRSponge
URS00000AA464 SHMT2 20304954 21512034 23622248 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,clash,miRNA interference luciferase reporter assay TarBase
URS000041FA2C SHMT2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 SHMT2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BE495 SHMT2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 SHMT2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000001A7A SHMT2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D SHMT2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 SHMT2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F SHMT2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 SHMT2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 SHMT2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000553F51 SHMT2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000AF45F SHMT2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A92 SHMT2 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FARS2 SHMT2 25348397 N/A physical interaction ComPPI
CUL5 SHMT2 25348397 N/A physical interaction ComPPI
SAP30BP SHMT2 25348397 N/A physical interaction ComPPI
CHCHD2 SHMT2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
DYNLL1 SHMT2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLEKHF2 SHMT2 25348397 N/A physical interaction ComPPI
EIF1B SHMT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
COX5B SHMT2 25348397 N/A physical interaction ComPPI
NDC80 SHMT2 25348397 N/A physical interaction ComPPI
TBC1D7 SHMT2 25348397 N/A physical interaction ComPPI
DYNLL2 SHMT2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
BOLA1 SHMT2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
PSMC3 SHMT2 25348397 N/A physical interaction ComPPI
ATF4 SHMT2 25348397 N/A physical interaction ComPPI
NUTF2 SHMT2 25348397 N/A physical interaction ComPPI
PBX2 SHMT2 25348397 N/A physical interaction ComPPI
STAT1 SHMT2 25348397 N/A physical interaction ComPPI
FASTKD3 SHMT2 20869947 24234451 25348397 association tandem affinity purification ComPPI,IntAct
TP53BP1 SHMT2 25348397 N/A physical interaction ComPPI
GTF2A1 SHMT2 25348397 N/A physical interaction ComPPI
LMNA SHMT2 25348397 N/A physical interaction ComPPI
VPS11 SHMT2 25348397 N/A physical interaction ComPPI
TYK2 SHMT2 25348397 N/A physical interaction ComPPI
KEAP1 SHMT2 25348397 N/A physical interaction ComPPI
ZNF544 SHMT2 25348397 N/A physical interaction ComPPI
CPSF7 SHMT2 25348397 N/A physical interaction ComPPI
KASH5 SHMT2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
MAL2 SHMT2 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NDUFAF4 SHMT2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
PAK5 SHMT2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
H4C1 SHMT2 25348397 N/A physical interaction ComPPI
ABRAXAS2 SHMT2 25348397 N/A physical interaction ComPPI
MPDZ SHMT2 25348397 N/A physical interaction ComPPI
RAB8A SHMT2 25348397 N/A physical interaction ComPPI
PPP1R8 SHMT2 25348397 N/A physical interaction ComPPI
GRB2 SHMT2 12577067 24234451 25348397 association pull down ComPPI,IntAct
JUN SHMT2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
NFYA SHMT2 25348397 N/A physical interaction ComPPI
POLA1 SHMT2 25348397 N/A physical interaction ComPPI
ARHGEF3 SHMT2 25348397 N/A physical interaction ComPPI
RHOA SHMT2 25348397 N/A physical interaction ComPPI
DGKQ SHMT2 25348397 N/A physical interaction ComPPI
U2AF2 SHMT2 25348397 N/A physical interaction ComPPI
CUL3 SHMT2 25348397 N/A physical interaction ComPPI
RASSF9 SHMT2 25348397 N/A physical interaction ComPPI
YWHAZ SHMT2 25348397 N/A physical interaction ComPPI
CHP1 SHMT2 25348397 N/A physical interaction ComPPI
HGS SHMT2 25348397 N/A physical interaction ComPPI
IFNAR1 SHMT2 25348397 N/A physical interaction ComPPI
DLD SHMT2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
ARFIP1 SHMT2 25348397 N/A physical interaction ComPPI
NTRK1 SHMT2 25348397 N/A physical interaction ComPPI
NIT1 SHMT2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
PRMT1 SHMT2 25348397 N/A physical interaction ComPPI
IFNGR1 SHMT2 25348397 N/A physical interaction ComPPI
COPB1 SHMT2 25348397 N/A physical interaction ComPPI
SNX1 SHMT2 25348397 N/A physical interaction ComPPI
COPA SHMT2 25348397 N/A physical interaction ComPPI
TLN1 SHMT2 25348397 N/A physical interaction ComPPI
ILK SHMT2 25348397 N/A physical interaction ComPPI
SNX6 SHMT2 25348397 N/A physical interaction ComPPI
PARP1 SHMT2 25348397 N/A physical interaction ComPPI
HSPA5 SHMT2 25348397 N/A physical interaction ComPPI
FEN1 SHMT2 25348397 N/A physical interaction ComPPI
POLDIP2 SHMT2 25348397 N/A physical interaction ComPPI
XRN2 SHMT2 25348397 N/A physical interaction ComPPI
PXN SHMT2 25348397 N/A physical interaction ComPPI
HMG20A SHMT2 25348397 N/A physical interaction ComPPI
TRIP6 SHMT2 25348397 N/A physical interaction ComPPI
XRCC6 SHMT2 25348397 N/A physical interaction ComPPI
HMGB2 SHMT2 25348397 N/A physical interaction ComPPI
EIF4EBP1 SHMT2 25348397 N/A physical interaction ComPPI
GORASP2 SHMT2 25348397 N/A physical interaction ComPPI
PDLIM7 SHMT2 25348397 N/A physical interaction ComPPI
EIF6 SHMT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAWR SHMT2 25348397 N/A physical interaction ComPPI
S100A11 SHMT2 25348397 N/A physical interaction ComPPI
NDRG1 SHMT2 14525934 17220478 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
TPM3 SHMT2 25348397 N/A physical interaction ComPPI
ZNF76 SHMT2 25348397 N/A physical interaction ComPPI
MYO18A SHMT2 25348397 N/A physical interaction ComPPI
PDHA1 SHMT2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CTR9 SHMT2 25348397 N/A physical interaction ComPPI
PPARD SHMT2 25348397 N/A physical interaction ComPPI
USP6NL SHMT2 25348397 N/A physical interaction ComPPI
RAB5B SHMT2 25348397 N/A physical interaction ComPPI
RAPGEF6 SHMT2 25348397 N/A physical interaction ComPPI
RAP2A SHMT2 25348397 N/A physical interaction ComPPI
EXOC2 SHMT2 25348397 N/A physical interaction ComPPI
RBM10 SHMT2 25348397 N/A physical interaction ComPPI
GRK6 SHMT2 25348397 N/A physical interaction ComPPI
RCC1 SHMT2 25348397 N/A physical interaction ComPPI
E2F2 SHMT2 25348397 N/A physical interaction ComPPI
LIN9 SHMT2 25348397 N/A physical interaction ComPPI
HUWE1 SHMT2 25348397 N/A physical interaction ComPPI
SRSF1 SHMT2 25348397 N/A physical interaction ComPPI
CUL2 SHMT2 25348397 N/A physical interaction ComPPI
BIN1 SHMT2 25348397 N/A physical interaction ComPPI
CUL1 SHMT2 25348397 N/A physical interaction ComPPI
TRERF1 SHMT2 25348397 N/A physical interaction ComPPI
ADRB2 SHMT2 25348397 N/A physical interaction ComPPI
YWHAE SHMT2 25348397 N/A physical interaction ComPPI
H1-5 SHMT2 25348397 N/A physical interaction ComPPI
MAPK12 SHMT2 25348397 N/A physical interaction ComPPI
CTTN SHMT2 25348397 N/A physical interaction ComPPI
AKAP8L SHMT2 25348397 N/A physical interaction ComPPI
HSPA4 SHMT2 25348397 N/A physical interaction ComPPI
MEF2D SHMT2 25348397 N/A physical interaction ComPPI
FBXO5 SHMT2 25348397 N/A physical interaction ComPPI
GTF2E2 SHMT2 25348397 N/A physical interaction ComPPI
FNBP1 SHMT2 25348397 N/A physical interaction ComPPI
ABI2 SHMT2 25348397 N/A physical interaction ComPPI
HDAC6 SHMT2 25348397 N/A physical interaction ComPPI
ACTL6A SHMT2 25348397 N/A physical interaction ComPPI
PPHLN1 SHMT2 25348397 N/A physical interaction ComPPI
TMOD2 SHMT2 25348397 N/A physical interaction ComPPI
TUBGCP3 SHMT2 25348397 N/A physical interaction ComPPI
HSPA9 SHMT2 25348397 N/A physical interaction ComPPI
RIPK2 SHMT2 25348397 N/A physical interaction ComPPI
MADD SHMT2 25348397 N/A physical interaction ComPPI
MED28 SHMT2 25348397 N/A physical interaction ComPPI
EFEMP1 SHMT2 25348397 N/A physical interaction ComPPI
CREB3 SHMT2 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EBP SHMT2 25348397 N/A physical interaction ComPPI
CUL7 SHMT2 25348397 N/A physical interaction ComPPI
LRPPRC SHMT2 25348397 N/A physical interaction ComPPI
HDAC5 SHMT2 25348397 N/A physical interaction ComPPI
CAND1 SHMT2 25348397 N/A physical interaction ComPPI
SUPT5H SHMT2 25348397 N/A physical interaction ComPPI
GSPT2 SHMT2 25348397 N/A physical interaction ComPPI
ALDOC SHMT2 25348397 N/A physical interaction ComPPI
SPN SHMT2 25348397 N/A physical interaction ComPPI
PDK1 SHMT2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RFXANK SHMT2 25348397 N/A physical interaction ComPPI
APAF1 SHMT2 25348397 N/A physical interaction ComPPI
HDAC7 SHMT2 25348397 N/A physical interaction ComPPI
HSPE1 SHMT2 25348397 N/A physical interaction ComPPI
SEC31A SHMT2 25348397 N/A physical interaction ComPPI
BACH1 SHMT2 25348397 N/A physical interaction ComPPI
DDX1 SHMT2 25348397 N/A physical interaction ComPPI
TCF12 SHMT2 25348397 N/A physical interaction ComPPI
TFB1M SHMT2 25348397 N/A physical interaction ComPPI
GNAS SHMT2 25348397 N/A physical interaction ComPPI
ELP2 SHMT2 25348397 N/A physical interaction ComPPI
IL18 SHMT2 25348397 N/A physical interaction ComPPI
PARG SHMT2 25348397 N/A physical interaction ComPPI
NOD1 SHMT2 25348397 N/A physical interaction ComPPI
PPP5C SHMT2 25348397 N/A physical interaction ComPPI
ARL6IP1 SHMT2 24234451 25348397 25416956 26871637 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NOP56 SHMT2 25348397 N/A physical interaction ComPPI
COPG2 SHMT2 25348397 N/A physical interaction ComPPI
BMP8B SHMT2 25348397 N/A physical interaction ComPPI
ILF2 SHMT2 20808282 24234451 25348397 association affinity chromatography technology,physical interaction ComPPI,IntAct
COPE SHMT2 25348397 N/A physical interaction ComPPI
STRN4 SHMT2 25348397 N/A physical interaction ComPPI
ESR1 SHMT2 25348397 N/A physical interaction ComPPI
MTOR SHMT2 25348397 N/A physical interaction ComPPI
VPS35 SHMT2 25348397 N/A physical interaction ComPPI
SSH3 SHMT2 25348397 N/A physical interaction ComPPI
PAFAH1B2 SHMT2 25348397 N/A physical interaction ComPPI
STAT3 SHMT2 25348397 N/A physical interaction ComPPI
SMARCC2 SHMT2 25348397 N/A physical interaction ComPPI
MEIS1 SHMT2 25348397 N/A physical interaction ComPPI
CAB39 SHMT2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STRADA SHMT2 25348397 N/A physical interaction ComPPI
ATP6V1A SHMT2 25348397 N/A physical interaction ComPPI
POLR1A SHMT2 25348397 N/A physical interaction ComPPI
MAP3K6 SHMT2 25348397 N/A physical interaction ComPPI
MBD4 SHMT2 25348397 N/A physical interaction ComPPI
HEXIM1 SHMT2 25348397 N/A physical interaction ComPPI
RALY SHMT2 25348397 N/A physical interaction ComPPI
AURKAIP1 SHMT2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HNRNPAB SHMT2 25348397 N/A physical interaction ComPPI
PRKAB1 SHMT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
UIMC1 SHMT2 25348397 N/A physical interaction ComPPI
H2AC4 SHMT2 25348397 N/A physical interaction ComPPI
DCTN2 SHMT2 25348397 N/A physical interaction ComPPI
ARID1A SHMT2 25348397 N/A physical interaction ComPPI
FBXW11 SHMT2 25348397 N/A physical interaction ComPPI
NASP SHMT2 25348397 N/A physical interaction ComPPI
HINFP SHMT2 25348397 N/A physical interaction ComPPI
TNFRSF10D SHMT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IKBKE SHMT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CEP250 SHMT2 25348397 N/A physical interaction ComPPI
TTK SHMT2 25348397 N/A physical interaction ComPPI
HNRNPM SHMT2 25348397 N/A physical interaction ComPPI
ARL2BP SHMT2 25348397 N/A physical interaction ComPPI
CSNK2B SHMT2 10549165 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
KIRREL3 SHMT2 24234451 25348397 25902260 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,fluorescence microscopy ComPPI,IntAct
ATF2 SHMT2 22304920 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LUC7L2 SHMT2 25348397 N/A physical interaction ComPPI
FNBP1L SHMT2 25348397 N/A physical interaction ComPPI
ATG7 SHMT2 25348397 N/A physical interaction ComPPI
PIN4 SHMT2 25348397 N/A physical interaction ComPPI
DHX38 SHMT2 25348397 N/A physical interaction ComPPI
GIPC3 SHMT2 25348397 N/A physical interaction ComPPI
PMPCB SHMT2 25348397 N/A physical interaction ComPPI
HEBP2 SHMT2 25348397 N/A physical interaction ComPPI
IVNS1ABP SHMT2 25348397 N/A physical interaction ComPPI
SHMT2 GNAS 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SHMT2 GNAS 25348397 N/A physical interaction ComPPI
SHMT2 BRCC3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHMT2 BABAM2 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHMT2 BABAM1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHMT2 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHMT2 MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHMT2 APP 25348397 N/A physical interaction ComPPI
SHMT2 IDE 25348397 N/A physical interaction ComPPI
SHMT2 CYHR1 25348397 N/A physical interaction ComPPI
SHMT2 H1-10 25348397 N/A physical interaction ComPPI
SHMT2 JMJD6 25348397 N/A physical interaction ComPPI
SHMT2 PSMG3 25348397 N/A physical interaction ComPPI
SHMT2 SEC24D 25348397 N/A physical interaction ComPPI
SHMT2 SHMT1 25348397 N/A physical interaction ComPPI
SHMT2 TBC1D15 25348397 N/A physical interaction ComPPI
SHMT2 CMTM5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SHMT2 NOC2L 25348397 N/A physical interaction ComPPI
SHMT2 HES4 25348397 N/A physical interaction ComPPI
SHMT2 UBR4 25348397 N/A physical interaction ComPPI
SHMT2 HP1BP3 25348397 N/A physical interaction ComPPI
SHMT2 RSRP1 25348397 N/A physical interaction ComPPI
SHMT2 ZBTB8OS 25348397 N/A physical interaction ComPPI
SHMT2 YARS1 25348397 N/A physical interaction ComPPI
SHMT2 KIAA0754 25348397 N/A physical interaction ComPPI
SHMT2 SZT2 25348397 N/A physical interaction ComPPI
SHMT2 LRRC42 25348397 N/A physical interaction ComPPI
SHMT2 MRPL37 25348397 N/A physical interaction ComPPI
SHMT2 DNAJB4 25348397 N/A physical interaction ComPPI
SHMT2 KYAT3 25348397 N/A physical interaction ComPPI
SHMT2 PALMD 25348397 N/A physical interaction ComPPI
SHMT2 STRIP1 25348397 N/A physical interaction ComPPI
SHMT2 NOTCH2NLA 25348397 N/A physical interaction ComPPI
SHMT2 MRPS21 25348397 N/A physical interaction ComPPI
SHMT2 GOLPH3L 25348397 N/A physical interaction ComPPI
SHMT2 PRUNE1 25348397 N/A physical interaction ComPPI
SHMT2 KHDC4 25348397 N/A physical interaction ComPPI
SHMT2 NDUFS2 25348397 N/A physical interaction ComPPI
SHMT2 RABGAP1L 25348397 N/A physical interaction ComPPI
SHMT2 RABGAP1L 25348397 N/A physical interaction ComPPI
SHMT2 AHCTF1 25348397 N/A physical interaction ComPPI
SHMT2 FAM110C 25348397 N/A physical interaction ComPPI
SHMT2 PTRHD1 25348397 N/A physical interaction ComPPI
SHMT2 GPATCH11 25348397 N/A physical interaction ComPPI
SHMT2 CAMKMT 25348397 N/A physical interaction ComPPI
SHMT2 PDCL3 25348397 N/A physical interaction ComPPI
SHMT2 NPAS2 25348397 N/A physical interaction ComPPI
SHMT2 IWS1 25348397 N/A physical interaction ComPPI
SHMT2 NAB1 25348397 N/A physical interaction ComPPI
SHMT2 FAM117B 25348397 N/A physical interaction ComPPI
SHMT2 COL4A3 25348397 N/A physical interaction ComPPI
SHMT2 HJURP 25348397 N/A physical interaction ComPPI
SHMT2 ATG4B 25348397 N/A physical interaction ComPPI
SHMT2 ZNF860 25348397 N/A physical interaction ComPPI
SHMT2 RBM6 25348397 N/A physical interaction ComPPI
SHMT2 THOC7 25348397 N/A physical interaction ComPPI
SHMT2 MIX23 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHMT2 ISY1 25348397 N/A physical interaction ComPPI
SHMT2 RYK 25348397 N/A physical interaction ComPPI
SHMT2 MRPS22 25348397 N/A physical interaction ComPPI
SHMT2 ABCC5 25348397 N/A physical interaction ComPPI
SHMT2 XXYLT1 25348397 N/A physical interaction ComPPI
SHMT2 EVC 25348397 N/A physical interaction ComPPI
SHMT2 GRPEL1 25348397 N/A physical interaction ComPPI
SHMT2 OCIAD1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHMT2 MRPS18C 25348397 N/A physical interaction ComPPI
SHMT2 WDFY3 25348397 N/A physical interaction ComPPI
SHMT2 HERC3 25348397 N/A physical interaction ComPPI
SHMT2 FAT4 25348397 N/A physical interaction ComPPI
SHMT2 TNFAIP8 25348397 N/A physical interaction ComPPI
SHMT2 HARS2 25348397 N/A physical interaction ComPPI
SHMT2 FBXO38 25348397 N/A physical interaction ComPPI
SHMT2 STK10 25348397 N/A physical interaction ComPPI
SHMT2 BPHL 25348397 N/A physical interaction ComPPI
SHMT2 RNF144B 25348397 N/A physical interaction ComPPI
SHMT2 H2BC17 25348397 N/A physical interaction ComPPI
SHMT2 MRPS10 25348397 N/A physical interaction ComPPI
SHMT2 SNX14 25348397 N/A physical interaction ComPPI
SHMT2 ZUP1 25348397 N/A physical interaction ComPPI
SHMT2 SCAF8 25348397 N/A physical interaction ComPPI
SHMT2 WDR27 25348397 N/A physical interaction ComPPI
SHMT2 SNX8 25348397 N/A physical interaction ComPPI
SHMT2 CRCP 25348397 N/A physical interaction ComPPI
SHMT2 GATAD1 25348397 N/A physical interaction ComPPI
SHMT2 SAMD9 25348397 N/A physical interaction ComPPI
SHMT2 PTCD1 25348397 N/A physical interaction ComPPI
SHMT2 PSMC2 25348397 N/A physical interaction ComPPI
SHMT2 NUP205 25348397 N/A physical interaction ComPPI
SHMT2 ABCF2 25348397 N/A physical interaction ComPPI
SHMT2 DMTN 25348397 N/A physical interaction ComPPI
SHMT2 BIN3 25348397 N/A physical interaction ComPPI
SHMT2 MTFR1 25348397 N/A physical interaction ComPPI
SHMT2 STAU2 25348397 N/A physical interaction ComPPI
SHMT2 GDAP1 25348397 N/A physical interaction ComPPI
SHMT2 DECR1 25348397 N/A physical interaction ComPPI
SHMT2 UTP23 25348397 N/A physical interaction ComPPI
SHMT2 ZNF623 25348397 N/A physical interaction ComPPI
SHMT2 SCRIB 25348397 N/A physical interaction ComPPI
SHMT2 KANK1 25348397 N/A physical interaction ComPPI
SHMT2 PUM3 25348397 N/A physical interaction ComPPI
SHMT2 KDM4C 25348397 N/A physical interaction ComPPI
SHMT2 ACO1 25348397 N/A physical interaction ComPPI
SHMT2 NFX1 25348397 N/A physical interaction ComPPI
SHMT2 UBAP1 25348397 N/A physical interaction ComPPI
SHMT2 HINT2 25348397 N/A physical interaction ComPPI
SHMT2 C9ORF40 25348397 N/A physical interaction ComPPI
SHMT2 NOL8 25348397 N/A physical interaction ComPPI
SHMT2 NANS 25348397 N/A physical interaction ComPPI
SHMT2 CCP110 25348397 N/A physical interaction ComPPI
SHMT2 TTLL11 25348397 N/A physical interaction ComPPI
SHMT2 KYAT1 25348397 N/A physical interaction ComPPI
SHMT2 DPH7 25348397 N/A physical interaction ComPPI
SHMT2 KIAA1217 25348397 N/A physical interaction ComPPI
SHMT2 BMS1 25348397 N/A physical interaction ComPPI
SHMT2 HERC4 25348397 N/A physical interaction ComPPI
SHMT2 DNA2 25348397 N/A physical interaction ComPPI
SHMT2 AGAP11 25348397 N/A physical interaction ComPPI
SHMT2 GOT1 25348397 N/A physical interaction ComPPI
SHMT2 ARMH3 25348397 N/A physical interaction ComPPI
SHMT2 BBIP1 25348397 N/A physical interaction ComPPI
SHMT2 DNHD1 25348397 N/A physical interaction ComPPI
SHMT2 ZNF215 25348397 N/A physical interaction ComPPI
SHMT2 ELP4 25348397 N/A physical interaction ComPPI
SHMT2 NDUFS3 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHMT2 RELT 25348397 N/A physical interaction ComPPI
SHMT2 ANKRD49 25348397 N/A physical interaction ComPPI
SHMT2 AMOTL1 25348397 N/A physical interaction ComPPI
SHMT2 ENDOD1 25348397 N/A physical interaction ComPPI
SHMT2 CEP164 25348397 N/A physical interaction ComPPI
SHMT2 FOXRED1 25348397 N/A physical interaction ComPPI
SHMT2 CPNE8 25348397 N/A physical interaction ComPPI
SHMT2 KIF21A 25348397 N/A physical interaction ComPPI
SHMT2 LIMA1 25348397 N/A physical interaction ComPPI
SHMT2 CS 25348397 N/A physical interaction ComPPI
SHMT2 SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHMT2 INHBE 25348397 N/A physical interaction ComPPI
SHMT2 NTN4 25348397 N/A physical interaction ComPPI
SHMT2 RNF10 25348397 N/A physical interaction ComPPI
SHMT2 USPL1 25348397 N/A physical interaction ComPPI
SHMT2 INTS6 25348397 N/A physical interaction ComPPI
SHMT2 PIBF1 25348397 N/A physical interaction ComPPI
SHMT2 PCID2 25348397 N/A physical interaction ComPPI
SHMT2 MLH3 25348397 N/A physical interaction ComPPI
SHMT2 FLVCR2 25348397 N/A physical interaction ComPPI
SHMT2 DDX24 25348397 N/A physical interaction ComPPI
SHMT2 BTBD6 25348397 N/A physical interaction ComPPI
SHMT2 AQR 25348397 N/A physical interaction ComPPI
SHMT2 KNSTRN 25348397 N/A physical interaction ComPPI
SHMT2 ADAL 25348397 N/A physical interaction ComPPI
SHMT2 MYZAP 25348397 N/A physical interaction ComPPI
SHMT2 MYO1E 25348397 N/A physical interaction ComPPI
SHMT2 RHBDF1 25348397 N/A physical interaction ComPPI
SHMT2 CLUAP1 25348397 N/A physical interaction ComPPI
SHMT2 CCDC189 25348397 N/A physical interaction ComPPI
SHMT2 RPGRIP1L 25348397 N/A physical interaction ComPPI
SHMT2 EDC4 25348397 N/A physical interaction ComPPI
SHMT2 NFATC3 25348397 N/A physical interaction ComPPI
SHMT2 PDPR 25348397 N/A physical interaction ComPPI
SHMT2 OSGIN1 25348397 N/A physical interaction ComPPI
SHMT2 KLHDC4 25348397 N/A physical interaction ComPPI
SHMT2 PRPF8 25348397 N/A physical interaction ComPPI
SHMT2 WDR81 25348397 N/A physical interaction ComPPI
SHMT2 CHD3 25348397 N/A physical interaction ComPPI
SHMT2 PFAS 25348397 N/A physical interaction ComPPI
SHMT2 COPRS 25348397 N/A physical interaction ComPPI
SHMT2 ZNF207 25348397 N/A physical interaction ComPPI
SHMT2 RAPGEFL1 25348397 N/A physical interaction ComPPI
SHMT2 NT5C3B 25348397 N/A physical interaction ComPPI
SHMT2 AOC2 25348397 N/A physical interaction ComPPI
SHMT2 DHX8 25348397 N/A physical interaction ComPPI
SHMT2 LUC7L3 25348397 N/A physical interaction ComPPI
SHMT2 MKS1 25348397 N/A physical interaction ComPPI
SHMT2 METTL2A 25348397 N/A physical interaction ComPPI
SHMT2 EXOC7 25348397 N/A physical interaction ComPPI
SHMT2 TBC1D16 25348397 N/A physical interaction ComPPI
SHMT2 FAM210A 25348397 N/A physical interaction ComPPI
SHMT2 TTC39C 25348397 N/A physical interaction ComPPI
SHMT2 MBD1 25348397 N/A physical interaction ComPPI
SHMT2 PIGN 25348397 N/A physical interaction ComPPI
SHMT2 ADNP2 25348397 N/A physical interaction ComPPI
SHMT2 WDR18 25348397 N/A physical interaction ComPPI
SHMT2 RNASEH2A 25348397 N/A physical interaction ComPPI
SHMT2 UNC13A 25348397 N/A physical interaction ComPPI
SHMT2 CRLF1 25348397 N/A physical interaction ComPPI
SHMT2 ZNF792 25348397 N/A physical interaction ComPPI
SHMT2 ATP1A3 25348397 N/A physical interaction ComPPI
SHMT2 CADM4 25348397 N/A physical interaction ComPPI
SHMT2 ZNF419 25348397 N/A physical interaction ComPPI
SHMT2 ZNF8 25348397 N/A physical interaction ComPPI
SHMT2 A1BG 25348397 N/A physical interaction ComPPI
SHMT2 ITPA 25348397 N/A physical interaction ComPPI
SHMT2 ZNFX1 25348397 N/A physical interaction ComPPI
SHMT2 GMEB2 25348397 N/A physical interaction ComPPI
SHMT2 CRYZL1 25348397 N/A physical interaction ComPPI
SHMT2 NDUFV3 25348397 N/A physical interaction ComPPI
SHMT2 NIPSNAP1 25348397 N/A physical interaction ComPPI
SHMT2 TAB1 25348397 N/A physical interaction ComPPI
SHMT2 CA5B 25348397 N/A physical interaction ComPPI
SHMT2 SPIN4 25348397 N/A physical interaction ComPPI
SHMT2 MORC4 25348397 N/A physical interaction ComPPI
SHMT2 GLUD2 25348397 N/A physical interaction ComPPI
SHMT2 ENOX2 25348397 N/A physical interaction ComPPI
SHMT2 MBNL3 25348397 N/A physical interaction ComPPI
SHMT2 DKC1 25348397 N/A physical interaction ComPPI
SHMT2 OBSL1 25348397 N/A physical interaction ComPPI
SHMT2 NAPRT 25348397 N/A physical interaction ComPPI
SHMT2 SCLY 25348397 N/A physical interaction ComPPI
SHMT2 EZR 25348397 N/A physical interaction ComPPI
SHMT2 PRRC1 25348397 N/A physical interaction ComPPI
SHMT2 PPM1G 25348397 N/A physical interaction ComPPI
SHMT2 TMEM184A 25348397 N/A physical interaction ComPPI
SHMT2 SDHA 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SHMT2 SOAT1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SHMT2 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SHMT2 DEGS1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SHMT2 TRMT10C 18984158 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 SIRT4 24234451 25348397 25525879 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 DUX4 24234451 25348397 26816005 association pull down ComPPI,IntAct
SHMT2 AIFM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SHMT2 HSPD1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SHMT2 COX14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SHMT2 SFXN1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SHMT2 XPNPEP3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 SPATA20 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 PRELID1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 MICOS13 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 OXCT2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 OPA3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 NME4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 NDUFAF5 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 NDUFA4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 LYRM4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 COX6B1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 COQ9 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 COQ3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 COQ7 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 COQ10A 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 CISD3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 FMC1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 MAIP1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 GATD3B 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 SDHAF4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 DGLUCY 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 NDUFAF8 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 SDHAF3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 ABHD11 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
APEH SHMT2 25348397 N/A physical interaction ComPPI
MGST3 SHMT2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
FUNDC2 SHMT2 25348397 N/A physical interaction ComPPI
PTPN23 SHMT2 24234451 25348397 28330616 association pull down ComPPI,IntAct
DDX41 SHMT2 25348397 N/A physical interaction ComPPI
ALDH18A1 SHMT2 25348397 N/A physical interaction ComPPI
DDA1 SHMT2 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRMT61B SHMT2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ATP6V1C1 SHMT2 25348397 N/A physical interaction ComPPI
C1ORF21 SHMT2 25348397 N/A physical interaction ComPPI
SHMT2 SHMT2 11063567 14525934 N/A experimental interaction detection HPRD
METTL14 SHMT2 24234451 29507755 association anti tag coimmunoprecipitation IntAct
NCBP3 SHMT2 24234451 26382858 association pull down IntAct
SHMT2 KIAA0895 24234451 30021884 physical association cross-linking study IntAct
L1TD1 SHMT2 24234451 25702638 association anti bait coimmunoprecipitation IntAct

Source Target Pmid Interactiontype Methods Database
URS00009BE4DE SHMT2 27087310 direct interaction,inhibition N/A NPInter

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