GENE:SLC16A1
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | SLC16A1 |
FullNmae | solute carrier family 16 member 1 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:10922 |
EnsembleID | ENSG00000155380 |
Uniprot | P53985 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
SLC16A1 | cuproptosis | 36010978 | Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. | Cuproptosis-related genes |
Go Annotation:
GeneSymbol | Go id |
---|---|
SLC16A1 | GO:0005515,GO:0005813,GO:0005886,GO:0005886,GO:0005886,GO:0006629,GO:0007098,GO:0008028,GO:0008028,GO:0008028,GO:0009925,GO:0015129,GO:0015129,GO:0015130,GO:0015141,GO:0015650,GO:0015718,GO:0015718,GO:0015718,GO:0015728,GO:0016020,GO:0016323,GO:0016324,GO:0016324,GO:0016328,GO:0030054,GO:0032094,GO:0035879,GO:0035879,GO:0042593,GO:0042802,GO:0042867,GO:0043231,GO:0045202,GO:0046943,GO:0050796,GO:0051780,GO:0070062,GO:0071407,GO:0071422,GO:0097159,GO:0150104,GO:1901475,GO:1902600,GO:1905039 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
SLC16A1 | hsa:6566 | path:hsa04148 | Efferocytosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | SLC16A1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | SLC16A1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA2 | SLC16A1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
FOXP3 | SLC16A1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | SLC16A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | SLC16A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | SLC16A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | SLC16A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | SLC16A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | SLC16A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | SLC16A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | SLC16A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | SLC16A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | SLC16A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TRIM28 | SLC16A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
USF1 | SLC16A1 | 15691871 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00005651EE | SLC16A1 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
URS00003D5391 | SLC16A1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00003CF1AD | SLC16A1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000183BED | SLC16A1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000285DCB | SLC16A1 | 20371350 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001EFEC1 | SLC16A1 | 20371350 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000CBE63 | SLC16A1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001270D3 | SLC16A1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000070CD2 | SLC16A1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004719AB | SLC16A1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001BCAC5 | SLC16A1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000058DCD8 | SLC16A1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001DE669 | SLC16A1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000005CF5F | SLC16A1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000065D58 | SLC16A1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000079F78 | SLC16A1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000041E11D | SLC16A1 | 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000037E170 | SLC16A1 | 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001EE123 | SLC16A1 | 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004F24A9 | SLC16A1 | 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003AD2AA | SLC16A1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000076995 | SLC16A1 | 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000272A3D | SLC16A1 | 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000202460 | SLC16A1 | 20371350 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000D2680 | SLC16A1 | 20371350 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004283FE | SLC16A1 | 20371350 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004AE8D3 | SLC16A1 | 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000083D87 | SLC16A1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075ABF4 | SLC16A1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000308E4D | SLC16A1 | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000020CEC2 | SLC16A1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002CAE0C | SLC16A1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000585553 | SLC16A1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000030F801 | SLC16A1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004977C5 | SLC16A1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000048BA36 | SLC16A1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000EC1BE | SLC16A1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001481F9 | SLC16A1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075BDAA | SLC16A1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000086A4D | SLC16A1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000048D44E | SLC16A1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003E226A | SLC16A1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000027080C | SLC16A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000013ABA3 | SLC16A1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00001B341F | SLC16A1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000330617 | SLC16A1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000007F792 | SLC16A1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00002C02E4 | SLC16A1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000118224 | SLC16A1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000008AA34 | SLC16A1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000043D2C1 | SLC16A1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00005E1A16 | SLC16A1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
TOMM22 | SLC16A1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
TRAF6 | SLC16A1 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
MAP1LC3B | SLC16A1 | 20562859 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
NDUFAF4 | SLC16A1 | 24234451 25348397 27499296 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
CUL3 | SLC16A1 | 25348397 | N/A | physical interaction | ComPPI |
NTRK1 | SLC16A1 | 25348397 | N/A | physical interaction | ComPPI |
NIT1 | SLC16A1 | 24234451 25348397 27499296 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
ILK | SLC16A1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CFTR | SLC16A1 | 25348397 | N/A | physical interaction | ComPPI |
MAPK6 | SLC16A1 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
CUL2 | SLC16A1 | 25348397 | N/A | physical interaction | ComPPI |
TUBA1A | SLC16A1 | 24234451 25348397 29568061 | association | pull down | ComPPI,IntAct |
TENT5A | SLC16A1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
ATXN3 | SLC16A1 | 25348397 | N/A | physical interaction | ComPPI |
MME | SLC16A1 | 17342744 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
NR3C1 | SLC16A1 | 25348397 | N/A | physical interaction | ComPPI |
SLC16A1 | DEGS1 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
SLC16A1 | SERINC3 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
SLC16A1 | AP1S1 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
SLC16A1 | BSG | 10921872 14525934 25348397 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
SLC16A1 | CYSTM1 | 25348397 | N/A | physical interaction | ComPPI |
SLC16A1 | LGR4 | 25348397 | N/A | physical interaction | ComPPI |
SLC16A1 | UNK | 25348397 | N/A | physical interaction | ComPPI |
SLC16A1 | OTUB1 | 24234451 25348397 26752685 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
SLC16A1 | COQ9 | 25348397 | N/A | physical interaction | ComPPI |
SLC16A1 | PTPMT1 | 25348397 | N/A | physical interaction | ComPPI |
SLC16A1 | NDUFA4 | 25348397 | N/A | physical interaction | ComPPI |
SLC16A1 | NMES1 | 25348397 | N/A | physical interaction | ComPPI |
SLC16A1 | NDUFAF8 | 24234451 25348397 27499296 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
SLC16A1 | CISD3 | 25348397 | N/A | physical interaction | ComPPI |
SLC16A1 | NDUFS3 | 25348397 | N/A | physical interaction | ComPPI |
SLC16A1 | CHCHD10 | 25348397 | N/A | physical interaction | ComPPI |
SLC16A1 | CRBN | 25348397 | N/A | physical interaction | ComPPI |
SLC16A1 | SOAT1 | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
SLC16A1 | TRIM25 | 25348397 | N/A | physical interaction | ComPPI |
SLC16A1 | TSC22D1 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
SLC16A1 | RIPK4 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
SLC16A1 | LAMP1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
SLC16A1 | TGOLN2 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
SLC16A1 | MICOS13 | 24234451 25348397 27499296 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
SLC16A1 | COX6B1 | 24234451 25348397 27499296 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
CLN6 | SLC16A1 | 24234451 30177828 | association | anti tag coimmunoprecipitation | IntAct |
AGTR1 | SLC16A1 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
SLC16A1 | GARNL3 | 24234451 30021884 | physical association | cross-linking study | IntAct |
SLC16A1 | CEP43 | 24234451 30021884 | physical association | cross-linking study | IntAct |
SLC16A1 | THSD7A | 24234451 30021884 | physical association | cross-linking study | IntAct |
SLC16A1 | NGDN | 24234451 30021884 | physical association | cross-linking study | IntAct |