GENE：SLC25A19
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SLC25A19 |
| FullNmae | solute carrier family 25 member 19 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:14409 |
| EnsembleID | ENSG00000125454 |
| Uniprot | Q9HC21 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SLC25A19 | cuproptosis | 36010978 | Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. | Cuproptosis-related genes |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SLC25A19 | GO:0005634,GO:0005739,GO:0005743,GO:0009229,GO:0015234,GO:0015297,GO:0030233,GO:0030302,GO:0030974,GO:0030974,GO:0042723,GO:0090422,GO:0090422 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR1 | SLC25A19 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | SLC25A19 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | SLC25A19 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| MYCN | SLC25A19 | 16093321 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | SLC25A19 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | SLC25A19 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | SLC25A19 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | SLC25A19 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | SLC25A19 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | SLC25A19 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | SLC25A19 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | SLC25A19 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000338542 | SLC25A19 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS0000324096 | SLC25A19 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS000019F055 | SLC25A19 | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GEMIN7 | SLC25A19 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| JUN | SLC25A19 | 24234451 25348397 25609649 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| PTPN22 | SLC25A19 | 25348397 | N/A | physical interaction | ComPPI |
| HUWE1 | SLC25A19 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| POLR3E | SLC25A19 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| DUSP6 | SLC25A19 | 25348397 | N/A | physical interaction | ComPPI |
| ZWINT | SLC25A19 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CLTB | SLC25A19 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NXF1 | SLC25A19 | 25348397 | N/A | physical interaction | ComPPI |
| MOV10 | SLC25A19 | 25348397 | N/A | physical interaction | ComPPI |