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GENE：CDK11A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CDK11A
FullNmae cyclin dependent kinase 11A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1730
EnsembleID ENSG00000008128
Uniprot Q9UQ88

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CDK11A necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CDK11A mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CDK11A GO:0000278,GO:0001558,GO:0004672,GO:0004674,GO:0004674,GO:0004693,GO:0005524,GO:0005634,GO:0005634,GO:0005737,GO:0006355,GO:0006468,GO:0006468,GO:0006915,GO:0007346,GO:0050684,GO:0106310

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CDK11A CCNL1 22988298 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 CDK11A 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 CDK11A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
E2F1 CDK11A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CDK11A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CDK11A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 CDK11A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CREB1 CDK11A N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D CDK11A 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CDK11A SPDEF 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
KPNA2 CDK11A 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PIN1 CDK11A 25348397 N/A physical interaction ComPPI
SAP30BP CDK11A 25348397 N/A physical interaction ComPPI
HSPA8 CDK11A 25348397 N/A physical interaction ComPPI
YWHAG CDK11A 25348397 N/A physical interaction ComPPI
MCM6 CDK11A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MCM2 CDK11A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HSP90AB1 CDK11A 22939624 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
PAK1 CDK11A 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
CASP3 CDK11A 25348397 N/A in vivo ComPPI
JUN CDK11A 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
VDR CDK11A 25348397 N/A physical interaction ComPPI
SMAD3 CDK11A 25348397 N/A physical interaction,tandem affinity purification ComPPI
PNKP CDK11A 25348397 N/A physical interaction ComPPI
TGM2 CDK11A 25348397 N/A physical interaction ComPPI
KPNB1 CDK11A 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
YWHAB CDK11A 25348397 N/A physical interaction ComPPI
YWHAZ CDK11A 25348397 N/A physical interaction ComPPI
CDKN2A CDK11A 25348397 N/A physical interaction ComPPI
RPS27A CDK11A 25348397 N/A physical interaction ComPPI
HSP90AA1 CDK11A 19875381 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NTRK1 CDK11A 25348397 N/A physical interaction ComPPI
PRPF40A CDK11A 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CASP1 CDK11A 25348397 N/A in vitro,in vivo ComPPI
PELP1 CDK11A 25348397 N/A physical interaction ComPPI
CASP8 CDK11A 25348397 N/A in vivo ComPPI
CSNK2A1 CDK11A 23602568 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction,protein kinase assay,tandem affinity purification ComPPI,IntAct
UHRF2 CDK11A 25348397 N/A physical interaction ComPPI
ZNF510 CDK11A 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PSMD1 CDK11A 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RANBP9 CDK11A 25348397 N/A physical interaction ComPPI
PDHA1 CDK11A 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CTR9 CDK11A 25348397 N/A physical interaction ComPPI
EIF3F CDK11A 25348397 N/A physical interaction ComPPI
RAP1A CDK11A 25348397 N/A physical interaction ComPPI
YWHAQ CDK11A 25348397 N/A physical interaction ComPPI
SPRR3 CDK11A 25348397 N/A physical interaction ComPPI
CSNK2A2 CDK11A 23455922 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SOX2 CDK11A 25348397 N/A physical interaction ComPPI
H1-4 CDK11A 25348397 N/A physical interaction ComPPI
YWHAE CDK11A 25348397 N/A physical interaction ComPPI
HSPA4 CDK11A 25348397 N/A physical interaction ComPPI
SUPT16H CDK11A 25348397 N/A physical interaction ComPPI
NOLC1 CDK11A 25348397 N/A physical interaction ComPPI
CHEK2 CDK11A 23178491 24234451 25348397 association tandem affinity purification ComPPI,IntAct
SPAG9 CDK11A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ZRSR2 CDK11A 25348397 N/A physical interaction ComPPI
MSN CDK11A 25348397 N/A physical interaction ComPPI
KAT7 CDK11A 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
AP3D1 CDK11A 25348397 N/A physical interaction ComPPI
AP3B1 CDK11A 25348397 N/A physical interaction ComPPI
CDC37 CDK11A 24189400 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
AP2M1 CDK11A 25348397 N/A physical interaction ComPPI
DDB2 CDK11A 25348397 N/A physical interaction ComPPI
CCNL1 CDK11A 11683997 11980906 14623875 22988298 25348397 27898060 N/A physical interaction,in vitro ComPPI,OmniPath
CCNL2 CDK11A 25348397 N/A physical interaction ComPPI
EPS15L1 CDK11A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ESR1 CDK11A 25348397 N/A physical interaction ComPPI
MCM4 CDK11A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
AP4M1 CDK11A 25348397 N/A physical interaction ComPPI
CDK11B CDK11A 25348397 N/A physical interaction ComPPI
SRSF7 CDK11A 25348397 N/A two hybrid,in vivo ComPPI
RNPS1 CDK11A 25348397 27898060 9580558 N/A physical interaction,in vivo ComPPI,OmniPath
CSNK2B CDK11A 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TPPP CDK11A 25348397 N/A physical interaction ComPPI
IVNS1ABP CDK11A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ZNF33A CDK11A 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MED4 CDK11A 25348397 N/A physical interaction ComPPI
CCND3 CDK11A 25348397 N/A physical interaction ComPPI
GADD45A CDK11A 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
POU2F1 CDK11A 25348397 N/A physical interaction ComPPI
CDK11A B4GALT1 11506180 25348397 27898060 N/A physical interaction,in vitro ComPPI,OmniPath
CDK11A SKIV2L 15231747 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDK11A MEPCE 25348397 N/A physical interaction ComPPI
CDK11A HSP90AA2P 25348397 N/A physical interaction ComPPI
CDK11A RBM25 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK11A A2M 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK11A ZNF875 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK11A ZNF267 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK11A ZNF460 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK11A ZFP14 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK11A CDKN2A 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK11A NOP58 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK11A FKBP5 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK11A WDR47 25348397 N/A physical interaction ComPPI
CDK11A ZG16B 25348397 N/A physical interaction ComPPI
CDK11A CUSTOS 25348397 N/A physical interaction ComPPI
CDK11A CRNN 25348397 N/A physical interaction ComPPI
CDK11A DPF2 25348397 N/A physical interaction ComPPI
CDK11A FOXK2 25348397 N/A physical interaction ComPPI
CDK11A KMT2E 25348397 N/A physical interaction ComPPI
CDK11A JMJD6 25348397 N/A physical interaction ComPPI
CDK11A RSBN1 25348397 N/A physical interaction ComPPI
CDK11A ZNF221 25348397 N/A physical interaction ComPPI
CDK11A FGF8 25348397 N/A physical interaction ComPPI
CDK11A CCT6B 25348397 N/A physical interaction ComPPI
CDK11A CCT6A 25348397 N/A physical interaction ComPPI
CDK11A CCT2 25348397 N/A physical interaction ComPPI
CDK11A CCT3 25348397 N/A physical interaction ComPPI
CDK11A CCT4 25348397 N/A physical interaction ComPPI
CDK11A USP15 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK11A NCL 25348397 N/A physical interaction ComPPI
CDK11A BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
C18ORF25 CDK11A 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
LEO1 CDK11A 25348397 N/A physical interaction ComPPI
CDK11A EIF3F 12446680 19245811 27898060 inhibition N/A OmniPath
CDK11A CDK11B 21078675 27898060 stimulant N/A OmniPath

Visualization










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