Gene Information gene info

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GENE：SLFN11

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SLFN11
FullNmae schlafen family member 11
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26633
EnsembleID ENSG00000172716
Uniprot Q7Z7L1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SLFN11 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SLFN11 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
SLFN11 GO:0000049,GO:0000049,GO:0002376,GO:0004386,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005829,GO:0006338,GO:0006974,GO:0008156,GO:0016887,GO:0043111,GO:0051607,GO:0051607,GO:0090734,GO:2000134

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 SLFN11 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SLFN11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SLFN11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SLFN11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SLFN11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SLFN11 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001F0C23 SLFN11 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 SLFN11 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000209F04 SLFN11 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 SLFN11 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004AE8D3 SLFN11 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 SLFN11 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 SLFN11 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 SLFN11 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002AB575 SLFN11 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 SLFN11 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CIAO1 SLFN11 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HSP90AB1 SLFN11 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
NOTCH1 SLFN11 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PPP1R15A SLFN11 24234451 25348397 29109149 association anti tag coimmunoprecipitation ComPPI,IntAct
PPM1A SLFN11 25348397 N/A physical interaction ComPPI
HSP90AA1 SLFN11 25348397 N/A physical interaction ComPPI
RPA1 SLFN11 25348397 N/A physical interaction ComPPI
ECT2 SLFN11 25348397 N/A physical interaction ComPPI
RPA2 SLFN11 25348397 N/A physical interaction ComPPI
RPA3 SLFN11 25348397 N/A physical interaction ComPPI
SOX2 SLFN11 25348397 N/A physical interaction ComPPI
EGFR SLFN11 25348397 N/A physical interaction ComPPI
MMS19 SLFN11 25348397 N/A physical interaction ComPPI
BARD1 SLFN11 25348397 N/A physical interaction ComPPI
RPAP1 SLFN11 25348397 N/A physical interaction ComPPI

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