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GENE：SSBP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SSBP1
FullNmae single stranded DNA binding protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11317
EnsembleID ENSG00000106028
Uniprot Q04837

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SSBP1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SSBP1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
SSBP1 GO:0003682,GO:0003697,GO:0003697,GO:0003697,GO:0003723,GO:0005515,GO:0005634,GO:0005739,GO:0005759,GO:0006264,GO:0006268,GO:0042645,GO:0042645,GO:0042802,GO:0042803,GO:0051096,GO:0051096,GO:0051289,GO:0070062,GO:0070584,GO:0090297

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SSBP1 hsa:6742 path:hsa03030 DNA replication - Homo sapiens (human)
SSBP1 hsa:6742 path:hsa03430 Mismatch repair - Homo sapiens (human)
SSBP1 hsa:6742 path:hsa03440 Homologous recombination - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 SSBP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SSBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SSBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SSBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SSBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SSBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SSBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SSBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SSBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SSBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CHEK1 SSBP1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
CUL5 SSBP1 25348397 N/A physical interaction ComPPI
CKS1B SSBP1 25348397 N/A physical interaction ComPPI
HSPA8 SSBP1 25348397 N/A physical interaction ComPPI
GCM2 SSBP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LCA5 SSBP1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBL4A SSBP1 25348397 N/A physical interaction ComPPI
LMNA SSBP1 24234451 25348397 29568061 association pull down ComPPI,IntAct
GABARAPL2 SSBP1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NUDCD3 SSBP1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCUN1D1 SSBP1 25348397 N/A physical interaction ComPPI
KEAP1 SSBP1 25348397 N/A physical interaction ComPPI
MAP1LC3B SSBP1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SF3B4 SSBP1 25348397 N/A physical interaction ComPPI
MRPL23 SSBP1 25348397 N/A physical interaction ComPPI
SAMM50 SSBP1 25348397 N/A physical interaction ComPPI
GRB2 SSBP1 12577067 24234451 25348397 association pull down ComPPI,IntAct
JUN SSBP1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 SSBP1 25348397 N/A physical interaction ComPPI
SF3B1 SSBP1 25348397 N/A physical interaction ComPPI
CUL3 SSBP1 25348397 N/A physical interaction ComPPI
TUBA1B SSBP1 25348397 N/A physical interaction ComPPI
HSP90AA1 SSBP1 21360678 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YBX1 SSBP1 25348397 N/A physical interaction ComPPI
ILK SSBP1 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SSBP1 POLG 10827171 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
SSBP1 LDB1 12381786 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SSBP1 TAL1 25348397 N/A physical interaction ComPPI
SSBP1 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SSBP1 MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SSBP1 AGO4 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SSBP1 CKS2 25348397 N/A physical interaction ComPPI
SSBP1 CDK1 25348397 N/A physical interaction ComPPI
SSBP1 TCF3 25348397 N/A physical interaction ComPPI
SSBP1 CUL4A 25348397 N/A physical interaction ComPPI
SSBP1 CDK2 25348397 N/A physical interaction ComPPI
SSBP1 CUL1 25348397 N/A physical interaction ComPPI
SSBP1 CAND1 25348397 N/A physical interaction ComPPI
SSBP1 ERCC8 25348397 N/A physical interaction ComPPI
SSBP1 ERCC6 25348397 N/A physical interaction ComPPI
SSBP1 ERCC6 25348397 N/A physical interaction ComPPI
SSBP1 PWP1 25348397 N/A physical interaction ComPPI
SSBP1 SPRTN 25348397 N/A physical interaction ComPPI
SSBP1 NDUFS3 25348397 N/A physical interaction ComPPI
SSBP1 OGDH 25348397 N/A physical interaction ComPPI
SSBP1 DHODH 25348397 N/A physical interaction ComPPI
SSBP1 MRPL11 25348397 N/A physical interaction ComPPI
SSBP1 LAMTOR3 25348397 N/A physical interaction ComPPI
SSBP1 TUBA1C 25348397 N/A physical interaction ComPPI
SSBP1 HSPA5 25348397 N/A physical interaction ComPPI
SSBP1 MRPS16 25348397 N/A physical interaction ComPPI
SSBP1 MRPS2 25348397 N/A physical interaction ComPPI
SSBP1 EEF1A1 25348397 N/A physical interaction ComPPI
SSBP1 EEF1A1P5 25348397 N/A physical interaction ComPPI
SSBP1 SF3A1 25348397 N/A physical interaction ComPPI
SSBP1 SNX3 25348397 N/A physical interaction ComPPI
SSBP1 TUBB1 25348397 N/A physical interaction ComPPI
SSBP1 ALDH5A1 25348397 N/A physical interaction ComPPI
SSBP1 ACAT1 25348397 N/A physical interaction ComPPI
SSBP1 HSD17B4 25348397 N/A physical interaction ComPPI
SSBP1 CYC1 25348397 N/A physical interaction ComPPI
SSBP1 ILF3 25348397 N/A physical interaction ComPPI
SSBP1 HNRNPH3 25348397 N/A physical interaction ComPPI
SSBP1 NABP2 25348397 N/A physical interaction ComPPI
SSBP1 UQCRQ 25348397 N/A physical interaction ComPPI
SSBP1 SDHB 25348397 N/A physical interaction ComPPI
SSBP1 ATP5F1C 25348397 N/A physical interaction ComPPI
SSBP1 VDAC2 25348397 N/A physical interaction ComPPI
SSBP1 ATP6V1E1 25348397 N/A physical interaction ComPPI
SSBP1 TMEM126A 25348397 N/A physical interaction ComPPI
SSBP1 YME1L1 25348397 N/A physical interaction ComPPI
SSBP1 MYC 21150319 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SSBP1 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
SSBP1 HSP90AA2P 25348397 N/A physical interaction ComPPI
SSBP1 NOS2 25348397 N/A physical interaction ComPPI
SSBP1 PAN2 25348397 N/A physical interaction ComPPI
SSBP1 PRKN 25348397 N/A physical interaction ComPPI
SSBP1 ASB1 25348397 N/A physical interaction ComPPI
SSBP1 ASB2 25348397 N/A physical interaction ComPPI
SSBP1 ASB13 25348397 N/A physical interaction ComPPI
SSBP1 CEP57 25348397 N/A physical interaction ComPPI
SSBP1 FUS 25348397 N/A physical interaction ComPPI
SSBP1 INTS3 19759019 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SSBP1 INTS7 25348397 N/A physical interaction ComPPI
SSBP1 EGFR 25348397 N/A physical interaction ComPPI
SSBP1 UBE2A 25348397 N/A physical interaction ComPPI
SSBP1 UBE2B 25348397 N/A physical interaction ComPPI
SSBP1 KCMF1 25348397 N/A physical interaction ComPPI
SSBP1 TIAL1 25348397 N/A physical interaction ComPPI
SSBP1 CEP290 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SSBP1 CEP162 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SSBP1 PCM1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SSBP1 SCLT1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SSBP1 NFATC2 25348397 N/A physical interaction ComPPI
SSBP1 MTMR3 25348397 N/A physical interaction ComPPI
SSBP1 PTPN7 25348397 N/A physical interaction ComPPI
SSBP1 COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SSBP1 PARK7 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SSBP1 VDAC1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SSBP1 TRIM25 25348397 N/A physical interaction ComPPI
SSBP1 ZUP1 25348397 N/A physical interaction ComPPI
SSBP1 CFTR 25348397 N/A physical interaction ComPPI
SSBP1 MAP1LC3A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SSBP1 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SSBP1 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SSBP1 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SSBP1 MEX3C 22863774 24234451 25348397 association pull down ComPPI,IntAct
SSBP1 KDM4A 23871696 24234451 25348397 association pull down ComPPI,IntAct
SSBP1 CLPP 24234451 25348397 26058080 association proximity-dependent biotin identification ComPPI,IntAct
SSBP1 LGALS7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SSBP1 OTUD6A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SSBP1 ANG 24234451 25348397 28777577 association anti bait coimmunoprecipitation ComPPI,IntAct
SSBP1 AIFM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SSBP1 HSPD1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SSBP1 PDK1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SSBP1 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
MAPK6 SSBP1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
YWHAQ SSBP1 25348397 N/A physical interaction ComPPI
H3C1 SSBP1 25348397 N/A physical interaction ComPPI
AURKAIP1 SSBP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MGST3 SSBP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MALSU1 SSBP1 25348397 N/A physical interaction ComPPI
TRMT61B SSBP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SSBP1 SSBP1 14525934 9033597 N/A experimental interaction detection HPRD
SSBP1 TP53 19066201 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009C117C SSBP1 27087310 direct interaction,inhibition N/A NPInter

Visualization










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