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GENE：SUPT16H

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SUPT16H
FullNmae SPT16 homolog, facilitates chromatin remodeling subunit
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11465
EnsembleID ENSG00000092201
Uniprot Q9Y5B9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SUPT16H cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
SUPT16H GO:0003723,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0006260,GO:0006281,GO:0006334,GO:0006337,GO:0006366,GO:0006368,GO:0031491,GO:0032786,GO:0035101,GO:0035101

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SUPT16H EGR1 17209051 23180781 physical association anti tag coimmunoprecipitation InnateDB
CDK2 SUPT16H 21319273 23180781 physical association anti tag coimmunoprecipitation InnateDB
EED SUPT16H 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 SUPT16H 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 SUPT16H 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SUPT16H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SUPT16H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SUPT16H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SUPT16H 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D SUPT16H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C3AC1 SUPT16H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 SUPT16H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E SUPT16H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE SUPT16H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000003FD55 SUPT16H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000CF1D2 SUPT16H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 SUPT16H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000C85B2 SUPT16H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 SUPT16H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 SUPT16H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000235862 SUPT16H 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F SUPT16H 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 SUPT16H 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 SUPT16H 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000170D8B SUPT16H 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000759B6A SUPT16H 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 SUPT16H 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC SUPT16H 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 SUPT16H 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004F859B SUPT16H 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000535FDD SUPT16H 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 SUPT16H 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000041E11D SUPT16H 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000032BD73 SUPT16H 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D SUPT16H 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C SUPT16H 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 SUPT16H 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AURKB SUPT16H 22135298 phosphorylation N/A PhosphoSite
POLR2E SUPT16H 25361965 interaction type N/A PTMCode2
SUPT16H POLR2E 25361965 interaction type N/A PTMCode2
SUPT16H CSNK2A1 25361965 interaction type N/A PTMCode2
CSNK2A1 SUPT16H 25361965 interaction type N/A PTMCode2
SUPT16H POLR2C 25361965 interaction type N/A PTMCode2
POLR2C SUPT16H 25361965 interaction type N/A PTMCode2
SUPT16H PAF1 25361965 interaction type N/A PTMCode2
PAF1 SUPT16H 25361965 interaction type N/A PTMCode2
SUPT16H SUPT4H1 25361965 interaction type N/A PTMCode2
SUPT4H1 SUPT16H 25361965 interaction type N/A PTMCode2
SUPT16H NEK9 25361965 interaction type N/A PTMCode2
NEK9 SUPT16H 25361965 interaction type N/A PTMCode2
SUPT16H SSRP1 25361965 interaction type N/A PTMCode2
SSRP1 SUPT16H 25361965 interaction type N/A PTMCode2
SUPT16H CHD1 25361965 interaction type N/A PTMCode2
CHD1 SUPT16H 25361965 interaction type N/A PTMCode2
SUPT16H BAZ1B 25361965 interaction type N/A PTMCode2
BAZ1B SUPT16H 25361965 interaction type N/A PTMCode2
SUPT16H TRIM33 25361965 interaction type N/A PTMCode2
TRIM33 SUPT16H 25361965 interaction type N/A PTMCode2
SUPT16H CDK9 25361965 interaction type N/A PTMCode2
CDK9 SUPT16H 25361965 interaction type N/A PTMCode2
SUPT16H SUPT5H 25361965 interaction type N/A PTMCode2
SUPT5H SUPT16H 25361965 interaction type N/A PTMCode2
SUPT16H RTF1 25361965 interaction type N/A PTMCode2
RTF1 SUPT16H 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC5L SUPT16H 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
DAXX SUPT16H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 SUPT16H 25348397 N/A physical interaction ComPPI
DDX21 SUPT16H 25348397 N/A physical interaction ComPPI
DHX15 SUPT16H 25348397 N/A physical interaction ComPPI
QRICH1 SUPT16H 25348397 N/A physical interaction ComPPI
FTH1 SUPT16H 25348397 N/A physical interaction ComPPI
NPM1 SUPT16H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLB SUPT16H 25348397 N/A physical interaction ComPPI
SNRPD1 SUPT16H 25348397 N/A physical interaction ComPPI
VCP SUPT16H 25348397 N/A physical interaction ComPPI
BMI1 SUPT16H 25348397 N/A physical interaction ComPPI
KEAP1 SUPT16H 25348397 N/A physical interaction ComPPI
H2AC11 SUPT16H 14525934 18206970 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
APLF SUPT16H 25348397 N/A physical interaction ComPPI
H4C1 SUPT16H 25348397 N/A physical interaction ComPPI
NF2 SUPT16H 25348397 N/A physical interaction ComPPI
RPL10 SUPT16H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CD81 SUPT16H 25348397 N/A physical interaction ComPPI
JUN SUPT16H 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
PNKP SUPT16H 25348397 N/A physical interaction ComPPI
MAFF SUPT16H 25348397 N/A physical interaction ComPPI
CUL3 SUPT16H 25348397 N/A physical interaction ComPPI
POLR1G SUPT16H 19214185 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
POLR1E SUPT16H 19214185 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAA1 SUPT16H 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DLD SUPT16H 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NTRK1 SUPT16H 25348397 N/A physical interaction ComPPI
PARP1 SUPT16H 25348397 N/A physical interaction ComPPI
WRN SUPT16H 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
XRCC5 SUPT16H 21679440 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
SREK1 SUPT16H 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
FMNL1 SUPT16H 25348397 N/A physical interaction ComPPI
MSH6 SUPT16H 25348397 N/A physical interaction ComPPI
POLL SUPT16H 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
HNRNPU SUPT16H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CSNK2A1 SUPT16H 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XRCC6 SUPT16H 25348397 N/A physical interaction ComPPI
HMGB2 SUPT16H 25348397 N/A physical interaction ComPPI
EEF1A1 SUPT16H 25348397 N/A physical interaction ComPPI
DCTN1 SUPT16H 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
UBR5 SUPT16H 25348397 N/A physical interaction ComPPI
HMGB1 SUPT16H 25348397 N/A physical interaction ComPPI
VDAC1 SUPT16H 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EWSR1 SUPT16H 25348397 N/A physical interaction ComPPI
PDHA1 SUPT16H 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CTR9 SUPT16H 25348397 N/A physical interaction ComPPI
RPA2 SUPT16H 25348397 N/A physical interaction ComPPI
RPA3 SUPT16H 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RPA4 SUPT16H 25348397 N/A physical interaction ComPPI
TAL1 SUPT16H 20603019 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ABCE1 SUPT16H 25348397 N/A physical interaction ComPPI
SUMO2 SUPT16H 25348397 N/A physical interaction ComPPI
MACROD1 SUPT16H 25348397 N/A physical interaction ComPPI
CDK2 SUPT16H 25348397 N/A physical interaction ComPPI
SOX2 SUPT16H 25348397 N/A physical interaction ComPPI
SFN SUPT16H 25348397 N/A physical interaction ComPPI
VHL SUPT16H 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RNF2 SUPT16H 25348397 N/A physical interaction ComPPI
SF3A1 SUPT16H 25348397 N/A physical interaction ComPPI
GTF2E2 SUPT16H 10792464 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,OmniPath
SUPT16H NEK9 14525934 14660563 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SUPT16H MCM4 14525934 16902406 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
SUPT16H MCM3 25348397 N/A in vivo ComPPI
SUPT16H BRCC3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT16H SSRP1 16902406 19214185 24234451 25348397 30021884 association,physical association anti bait coimmunoprecipitation,cross-linking study,physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SUPT16H CHD1L 25348397 N/A anti tag coimmunoprecipitation,physical interaction,physical interaction ComPPI
SUPT16H PAF1 25348397 N/A physical interaction ComPPI
SUPT16H H2AX 25348397 N/A physical interaction ComPPI
SUPT16H MRTFA 25348397 N/A physical interaction ComPPI
SUPT16H TRIM33 20603019 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT16H CDK9 20603019 24234451 25348397 association anti bait coimmunoprecipitation,molecular sieving,physical interaction ComPPI,IntAct
SUPT16H MMS22L 25348397 N/A physical interaction ComPPI
SUPT16H TONSL 21113133 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SUPT16H SMARCAD1 25348397 N/A physical interaction ComPPI
SUPT16H HDGF 21907836 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SUPT16H ELAVL1 25348397 N/A physical interaction ComPPI
SUPT16H CAND1 25348397 N/A physical interaction ComPPI
SUPT16H FYTTD1 25348397 N/A physical interaction ComPPI
SUPT16H CSNK2B 25348397 N/A physical interaction ComPPI
SUPT16H RTF1 25348397 N/A physical interaction ComPPI
SUPT16H TOP1 25348397 N/A physical interaction ComPPI
SUPT16H PRPF4B 25348397 N/A physical interaction ComPPI
SUPT16H SNRPD2 25348397 N/A physical interaction ComPPI
SUPT16H NCSTN 25348397 N/A physical interaction ComPPI
SUPT16H S100A9 25348397 N/A physical interaction ComPPI
SUPT16H HNRNPM 25348397 N/A physical interaction ComPPI
SUPT16H SNU13 25348397 N/A physical interaction ComPPI
SUPT16H PRPF6 25348397 N/A physical interaction ComPPI
SUPT16H PRPF3 25348397 N/A physical interaction ComPPI
SUPT16H ACIN1 25348397 N/A physical interaction ComPPI
SUPT16H EEF1A1P5 25348397 N/A physical interaction ComPPI
SUPT16H RBM25 25348397 N/A physical interaction ComPPI
SUPT16H PRPF8 25348397 N/A physical interaction ComPPI
SUPT16H USP39 25348397 N/A physical interaction ComPPI
SUPT16H MSH2 25348397 N/A physical interaction ComPPI
SUPT16H PSIP1 25348397 N/A physical interaction ComPPI
SUPT16H CENPA 25348397 N/A physical interaction ComPPI
SUPT16H ESR1 21182205 24234451 25348397 association affinity chromatography technology,physical interaction ComPPI,IntAct
SUPT16H IGSF8 25348397 N/A physical interaction ComPPI
SUPT16H ICAM1 25348397 N/A physical interaction ComPPI
SUPT16H SRPK2 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
SUPT16H ATRX 25348397 N/A physical interaction ComPPI
SUPT16H H2AC4 25348397 N/A physical interaction ComPPI
SUPT16H MOV10 25348397 N/A physical interaction ComPPI
SUPT16H NXF1 25348397 N/A physical interaction ComPPI
SUPT16H BRCA1 25348397 N/A physical interaction ComPPI
SUPT16H CUL7 25348397 N/A physical interaction ComPPI
SUPT16H OBSL1 25348397 N/A physical interaction ComPPI
SUPT16H EED 25348397 N/A physical interaction ComPPI
SUPT16H SPIN2B 25348397 N/A physical interaction ComPPI
SUPT16H SPIN1 25348397 N/A physical interaction ComPPI
SUPT16H RNF146 25348397 N/A physical interaction ComPPI
SUPT16H H2BC1 25348397 N/A physical interaction ComPPI
SUPT16H FBXW11 25348397 N/A physical interaction ComPPI
SUPT16H BRD3 25348397 N/A physical interaction ComPPI
SUPT16H CDK12 25348397 N/A physical interaction ComPPI
SUPT16H IWS1 25348397 N/A physical interaction ComPPI
SUPT16H NAP1L1 25348397 N/A physical interaction ComPPI
SUPT16H PES1 25348397 N/A physical interaction ComPPI
SUPT16H CDK11B 25348397 N/A physical interaction ComPPI
SUPT16H CDK11A 25348397 N/A physical interaction ComPPI
SUPT16H KRI1 25348397 N/A physical interaction ComPPI
SUPT16H TOP2B 25348397 N/A physical interaction ComPPI
SUPT16H ZC3H18 25348397 N/A physical interaction ComPPI
SUPT16H IFI16 25348397 N/A physical interaction ComPPI
SUPT16H MED4 25348397 N/A physical interaction ComPPI
SUPT16H CEP97 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SUPT16H CNTROB 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SUPT16H SPICE1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SUPT16H CEP164 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SUPT16H POC1B 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SUPT16H STIL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SUPT16H ETAA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT16H CENPQ 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT16H NANOGP8 25348397 N/A physical interaction ComPPI
SUPT16H NANOG 25348397 N/A physical interaction ComPPI
SUPT16H SBF1 25348397 N/A physical interaction ComPPI
SUPT16H MACROH2A2 25348397 N/A physical interaction ComPPI
SUPT16H XPC 25348397 N/A physical interaction ComPPI
SUPT16H NAA40 25348397 N/A physical interaction ComPPI
SUPT16H WDR76 25348397 N/A physical interaction ComPPI
SUPT16H ALX3 25348397 N/A physical interaction ComPPI
SUPT16H TEAD2 25348397 N/A physical interaction ComPPI
SUPT16H L3MBTL1 25348397 N/A physical interaction ComPPI
SUPT16H SIX2 25348397 N/A physical interaction ComPPI
SUPT16H COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SUPT16H TRIM25 25348397 N/A physical interaction ComPPI
SUPT16H YAP1 25348397 N/A physical interaction ComPPI
SUPT16H MTF1 25348397 N/A physical interaction ComPPI
SUPT16H H2AW 24234451 24352239 25348397 association pull down,physical interaction ComPPI,IntAct
SUPT16H MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SUPT16H HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SUPT16H GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SUPT16H CCT6A 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
SUPT16H PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SUPT16H HTR7 19486527 24234451 25348397 association tandem affinity purification ComPPI,IntAct
SUPT16H PYHIN1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
SUPT16H RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SUPT16H FBL 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SUPT16H IFIH1 24234451 25348397 29251827 association anti bait coimmunoprecipitation ComPPI,IntAct
H3C1 SUPT16H 24234451 25348397 29568061 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
H3-3A SUPT16H 14525934 15616580 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CETN1 SUPT16H 25348397 N/A physical interaction ComPPI
POLR1A SUPT16H 19214185 24234451 25348397 association chromatography technology,physical interaction ComPPI,IntAct
TIPIN SUPT16H 25348397 N/A physical interaction ComPPI
SRRM1 SUPT16H 25348397 N/A physical interaction ComPPI
IK SUPT16H 25348397 N/A physical interaction ComPPI
LEO1 SUPT16H 25348397 N/A physical interaction ComPPI
RNF20 SUPT16H 25348397 N/A physical interaction ComPPI
HMGB3 SUPT16H 25348397 N/A physical interaction ComPPI
SMARCB1 SUPT16H 24234451 30108113 association proximity-dependent biotin identification IntAct
PARP1 SUPT16H 16682447 18406329 27898060 inhibition,stimulant N/A OmniPath

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