GENE:SURF6
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | SURF6 |
FullNmae | surfeit 6 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:11478 |
EnsembleID | ENSG00000148296 |
Uniprot | O75683 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
SURF6 | cuproptosis | 36010978 | Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. | Cuproptosis-related genes |
Go Annotation:
GeneSymbol | Go id |
---|---|
SURF6 | GO:0001652,GO:0003677,GO:0003677,GO:0003723,GO:0003723,GO:0003723,GO:0005515,GO:0005654,GO:0005694,GO:0005730,GO:0005730,GO:0042273,GO:0042274 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ETS1 | SURF6 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
MYC | SURF6 | 12695333 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | SURF6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | SURF6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | SURF6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | SURF6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXP1 | SURF6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | SURF6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00001A7F58 | SURF6 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00004AC389 | SURF6 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000C4DB5 | SURF6 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000383DF4 | SURF6 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000475586 | SURF6 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004F2EB0 | SURF6 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075AB14 | SURF6 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000054DF42 | SURF6 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000DD591 | SURF6 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000000EF0B | SURF6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003E226A | SURF6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002CEB74 | SURF6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004818BD | SURF6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000366551 | SURF6 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075BDA4 | SURF6 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000070B1D | SURF6 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000032015F | SURF6 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
NPM1 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
RPL37A | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
SMAD2 | SURF6 | 20195357 24234451 25348397 | physical association | display technology | ComPPI,IntAct |
E4F1 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
HNRNPU | SURF6 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CSNK2A1 | SURF6 | 22113938 24234451 25348397 27705803 | phosphorylation reaction,association | physical interaction,protein kinase assay,tandem affinity purification | ComPPI,IntAct |
VDAC1 | SURF6 | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
PDHA1 | SURF6 | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
RPS6 | SURF6 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
CSNK2A2 | SURF6 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
RAB11A | SURF6 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
CDK7 | SURF6 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
CDK8 | SURF6 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
TRIM25 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
ESR2 | SURF6 | 21182203 24234451 25348397 | association | cosedimentation through density gradient | ComPPI,IntAct |
RPL6 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
TGOLN2 | SURF6 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
AURKB | SURF6 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
BET1 | SURF6 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
RPL14 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
DGCR8 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
FBL | SURF6 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
RPL30 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
H1-1 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
AIFM1 | SURF6 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
RPL22 | SURF6 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
SIRT7 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
PUM3 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
CNBP | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
NXF1 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
MOV10 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
EBNA1BP2 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
PRDM5 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
RPS8 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
MAK16 | SURF6 | 25348397 | N/A | physical interaction | ComPPI |
SURF6 | ZC3H3 | 25348397 | N/A | physical interaction | ComPPI |
SURF6 | FAM9B | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
SURF6 | DALLY | 24234451 25294943 25348397 | association | pull down | ComPPI,IntAct |
VAPB | SURF6 | 24234451 30021884 | physical association | cross-linking study | IntAct |
VAPA | SURF6 | 24234451 30021884 | physical association | cross-linking study | IntAct |