GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
TEFM
FullNmae
transcription elongation factor, mitochondrial
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:26223
EnsembleID
ENSG00000172171
Uniprot
Q96QE5
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
TEFM
pyroptosis
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
TEFM
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
TEFM
GO:0003723,GO:0005515,GO:0005739,GO:0005759,GO:0006119,GO:0006390,GO:0006390,GO:0006392,GO:0030337,GO:0030337,GO:0042645,GO:0042645,GO:1990904
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
TEFM
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
GATA2
TEFM
19941826
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
YBX1
TEFM
19151767
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
SMARCA4
TEFM
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CEBPA
TEFM
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F4
TEFM
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOXP1
TEFM
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
TEFM
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS00002075FA
TEFM
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
PPP1CC
TEFM
25348397
N/A
physical interaction
ComPPI
KBTBD7
TEFM
20562859
24234451
25348397
26496610
association,physical association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
CD44
TEFM
25348397
N/A
physical interaction
ComPPI
SDC2
TEFM
25348397
N/A
physical interaction
ComPPI
CUL3
TEFM
25348397
N/A
physical interaction
ComPPI
GABARAP
TEFM
20562859
24234451
25348397
association
anti tag coimmunoprecipitation
ComPPI,IntAct
ARIH1
TEFM
25348397
N/A
physical interaction
ComPPI
GKAP1
TEFM
24234451
25348397
physical association
physical interaction,inference by socio-affinity scoring
ComPPI,IntAct
Visualization