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GENE：TIMMDC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TIMMDC1
FullNmae translocase of inner mitochondrial membrane domain containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1321
EnsembleID ENSG00000113845
Uniprot Q9NPL8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TIMMDC1 cuproptosis 36118866 FeS Cluster cuproptosis gene
TIMMDC1 cuproptosis 36685880 A total of 43 CRGs were manually identified and used to investigate the effects of cuproptosis in HNSC in current study. cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
TIMMDC1 GO:0005515,GO:0005654,GO:0005739,GO:0005739,GO:0005743

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 TIMMDC1 20034404 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 TIMMDC1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 TIMMDC1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TIMMDC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TIMMDC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TIMMDC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TIMMDC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 TIMMDC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002075FA TIMMDC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001B12A4 TIMMDC1 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NDUFB9 TIMMDC1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COX5B TIMMDC1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FATE1 TIMMDC1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TIMMDC1 HGS 25348397 N/A physical interaction ComPPI
TIMMDC1 APP 25348397 N/A physical interaction ComPPI
TIMMDC1 ABCD3 25348397 N/A physical interaction ComPPI
TIMMDC1 RNF2 25348397 N/A physical interaction ComPPI
TIMMDC1 ARL5B 25348397 N/A physical interaction ComPPI
TIMMDC1 NDUFAF1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 ECSIT 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 ACAD9 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFC2 25348397 N/A physical interaction ComPPI
TIMMDC1 NDUFS5 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFA13 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 MT-ND1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 SAMM50 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 MTCH1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFA8 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 MT-ND4 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFA3 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFB6 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFB8 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 UQCR10 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFS2 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 COX6B1 24234451 24344204 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFB10 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFS7 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFB4 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFS8 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFV1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 AFG3L2 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFA9 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 ATP5ME 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 MT-ND2 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFA12 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFV3 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 NDUFB5 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 LRPPRC 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 FAF2 25348397 N/A physical interaction ComPPI
TIMMDC1 NDUFA4 25348397 N/A physical interaction ComPPI
TIMMDC1 NDUFS3 25348397 N/A physical interaction ComPPI
TIMMDC1 DUSP19 25348397 N/A physical interaction ComPPI
TIMMDC1 DUSP6 25348397 N/A physical interaction ComPPI
TIMMDC1 NDUFB11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TIMMDC1 PTPN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TIMMDC1 DRAM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TIMMDC1 GJB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TIMMDC1 MARCHF5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TIMMDC1 CCL4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TIMMDC1 BCAP31 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TIMMDC1 STX6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TIMMDC1 CREB3L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TIMMDC1 KIR2DL4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TIMMDC1 AIFM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TIMMDC1 SCO1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TIMMDC1 SFXN1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SMO TIMMDC1 24234451 28298427 physical association ubiquitin reconstruction IntAct

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