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GENE：TRRAP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TRRAP
FullNmae transformation/transcription domain associated protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12347
EnsembleID ENSG00000196367
Uniprot Q9Y4A5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TRRAP cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
TRRAP GO:0000124,GO:0000124,GO:0000124,GO:0000786,GO:0000812,GO:0003712,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005794,GO:0006281,GO:0006282,GO:0006325,GO:0006355,GO:0006355,GO:0006357,GO:0033276,GO:0033276,GO:0035267,GO:0035267,GO:0042981,GO:0043484,GO:0045893,GO:0051726,GO:1905168,GO:2000779

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TRRAP hsa:8295 path:hsa03082 ATP-dependent chromatin remodeling - Homo sapiens (human)
TRRAP hsa:8295 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TRRAP KAT5 14966270 23180781 physical association tandem affinity purification InnateDB
TRRAP DMAP1 14966270 23180781 physical association tandem affinity purification InnateDB
TRRAP ING3 14966270 23180781 physical association anti tag coimmunoprecipitation InnateDB
EED TRRAP 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR TRRAP 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 TRRAP 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 TRRAP 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 TRRAP 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 TRRAP 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 TRRAP 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 TRRAP 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TRRAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TRRAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TRRAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TRRAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 TRRAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 TRRAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TRRAP N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 TRRAP 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000065D58 TRRAP 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000FC8EB TRRAP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000512C88 TRRAP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 TRRAP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000007A060 TRRAP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 TRRAP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002367FA TRRAP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000001EB3 TRRAP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CC864 TRRAP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA TRRAP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 TRRAP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 TRRAP 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
ING2 TRRAP 25361965 interaction type N/A PTMCode2
TRRAP ING2 25361965 interaction type N/A PTMCode2
TADA3 TRRAP 25361965 interaction type N/A PTMCode2
TRRAP TADA3 25361965 interaction type N/A PTMCode2
BRD8 TRRAP 25361965 interaction type N/A PTMCode2
TRRAP BRD8 25361965 interaction type N/A PTMCode2
TELO2 TRRAP 25361965 interaction type N/A PTMCode2
TRRAP TELO2 25361965 interaction type N/A PTMCode2
TAF5L TRRAP 25361965 interaction type N/A PTMCode2
TRRAP TAF5L 25361965 interaction type N/A PTMCode2
KAT2B TRRAP 25361965 interaction type N/A PTMCode2
TRRAP KAT2B 25361965 interaction type N/A PTMCode2
TP53 TRRAP 25361965 interaction type N/A PTMCode2
TRRAP TP53 25361965 interaction type N/A PTMCode2
KAT2A TRRAP 25361965 interaction type N/A PTMCode2
TRRAP KAT2A 25361965 interaction type N/A PTMCode2
TAF6 TRRAP 25361965 interaction type N/A PTMCode2
TRRAP TAF6 25361965 interaction type N/A PTMCode2
DMAP1 TRRAP 25361965 interaction type N/A PTMCode2
TRRAP DMAP1 25361965 interaction type N/A PTMCode2
TAF10 TRRAP 25361965 interaction type N/A PTMCode2
TRRAP TAF10 25361965 interaction type N/A PTMCode2
TRRAP MAX 25361965 interaction type N/A PTMCode2
MAX TRRAP 25361965 interaction type N/A PTMCode2
TRRAP TAF5 25361965 interaction type N/A PTMCode2
TAF5 TRRAP 25361965 interaction type N/A PTMCode2
TRRAP MRGBP 25361965 interaction type N/A PTMCode2
MRGBP TRRAP 25361965 interaction type N/A PTMCode2
TRRAP ING1 25361965 interaction type N/A PTMCode2
ING1 TRRAP 25361965 interaction type N/A PTMCode2
TRRAP MYC 25361965 interaction type N/A PTMCode2
MYC TRRAP 25361965 interaction type N/A PTMCode2
TRRAP EP400 25361965 interaction type N/A PTMCode2
EP400 TRRAP 25361965 interaction type N/A PTMCode2
TRRAP ATXN7 25361965 interaction type N/A PTMCode2
ATXN7 TRRAP 25361965 interaction type N/A PTMCode2
TRRAP ACTL6A 25361965 interaction type N/A PTMCode2
ACTL6A TRRAP 25361965 interaction type N/A PTMCode2
CTNNB1 TRRAP 25361965 interaction type N/A PTMCode2
TRRAP CTNNB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MORF4L2 TRRAP 25348397 N/A physical interaction ComPPI
CDC5L TRRAP 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SGF29 TRRAP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NPM1 TRRAP 25348397 N/A physical interaction ComPPI
CDKN1A TRRAP 25348397 N/A physical interaction ComPPI
TAF9 TRRAP 25348397 N/A physical interaction ComPPI
MRGBP TRRAP 12963728 14525934 15647280 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,biochemical,in vitro ComPPI,HPRD,IntAct
SKP1 TRRAP 19066453 25348397 27898060 N/A physical interaction ComPPI,OmniPath
DCUN1D1 TRRAP 25348397 N/A physical interaction ComPPI
MRFAP1 TRRAP 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
FOXR2 TRRAP 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TAF6L TRRAP 25348397 N/A physical interaction ComPPI
TAF9B TRRAP 25348397 N/A physical interaction ComPPI
NFATC1 TRRAP 25348397 N/A physical interaction ComPPI
NCK1 TRRAP 25348397 N/A physical interaction ComPPI
USP7 TRRAP 25348397 25925205 27898060 N/A physical interaction ComPPI,OmniPath
KAT2B TRRAP 25348397 N/A physical interaction ComPPI
MED1 TRRAP 18418385 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MED24 TRRAP 25348397 N/A physical interaction ComPPI
STAT2 TRRAP 25348397 N/A physical interaction ComPPI
RUVBL1 TRRAP 20371770 24234451 25348397 26496610 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
E2F1 TRRAP 11418595 14525934 24234451 25348397 9708738 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
ING1 TRRAP 25348397 N/A physical interaction ComPPI
MYC TRRAP 14525934 17314511 17353931 21150319 24234451 25348397 9708738 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
HNRNPL TRRAP 25348397 N/A physical interaction ComPPI
SREBF1 TRRAP 25348397 N/A physical interaction ComPPI
SREBF2 TRRAP 25348397 N/A physical interaction ComPPI
NFATC2 TRRAP 25348397 N/A physical interaction ComPPI
E2F4 TRRAP 11418595 14525934 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
MORF4L1 TRRAP 25348397 N/A physical interaction ComPPI
BRD8 TRRAP 12963728 14525934 24234451 25348397 physical association experimental interaction detection,physical interaction,biochemical,in vitro,in vivo ComPPI,HPRD,IntAct
TADA3 TRRAP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAL1 TRRAP 25348397 N/A physical interaction ComPPI
SMNDC1 TRRAP 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MPHOSPH8 TRRAP 25348397 N/A physical interaction ComPPI
CUL1 TRRAP 25348397 N/A physical interaction ComPPI
CDC20 TRRAP 25348397 N/A physical interaction ComPPI
USF1 TRRAP 25348397 N/A physical interaction ComPPI
TAF4 TRRAP 18418385 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TAF6 TRRAP 25348397 N/A physical interaction ComPPI
MED23 TRRAP 25348397 N/A physical interaction ComPPI
TAF5 TRRAP 25348397 N/A physical interaction ComPPI
TRRAP ACTL6A 11839798 12963728 14525934 15647280 24234451 25348397 association,physical association affinity chromatography technology,experimental interaction detection,molecular sieving,physical interaction,in vivo ComPPI,HPRD,IntAct
TRRAP KAT2A 10373431 11931763 14525934 15115762 18418385 24234451 25348397 association affinity chromatography technology,anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,biochemical,in vitro,in vivo ComPPI,HPRD,IntAct
TRRAP BRCA1 14525934 16260778 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
TRRAP ATXN7 15115762 24234451 25348397 association,physical association anti bait coimmunoprecipitation,pull down,physical interaction,in vivo ComPPI,IntAct
TRRAP ESR1 11931763 14525934 16260778 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TRRAP MAX 10611234 14525934 25348397 N/A two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TRRAP EP400 25348397 N/A physical interaction ComPPI
TRRAP SUPT3H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRRAP AK6 25348397 N/A physical interaction ComPPI
TRRAP ATXN7L3 25348397 N/A physical interaction ComPPI
TRRAP USP22 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRRAP ENY2 25348397 N/A physical interaction ComPPI
TRRAP ING3 25348397 N/A physical interaction ComPPI
TRRAP KAT5 10966108 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRRAP OFD1 25348397 N/A physical interaction ComPPI
TRRAP CTNNB1 25348397 N/A physical interaction ComPPI
TRRAP TAF10 15115762 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TRRAP TTI1 20371770 24234451 25348397 26496610 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
TRRAP TELO2 18160036 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TRRAP TP53 25348397 N/A physical interaction ComPPI
TRRAP MED26 25348397 N/A physical interaction ComPPI
TRRAP CDK8 18418385 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction,ion exchange chromatography,biochemical ComPPI,IntAct
TRRAP MED12 25348397 N/A physical interaction ComPPI
TRRAP MED13 25348397 N/A physical interaction ComPPI
TRRAP MED14 25348397 N/A physical interaction ComPPI
TRRAP MED15 18418385 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TRRAP MED16 25348397 N/A physical interaction ComPPI
TRRAP MED17 25348397 N/A physical interaction ComPPI
TRRAP MED25 25348397 N/A physical interaction ComPPI
TRRAP NPAT 17967892 22288532 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TRRAP RIOX1 25348397 N/A physical interaction ComPPI
TRRAP DMAP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRRAP PYGO2 25348397 N/A physical interaction ComPPI
TRRAP SIRT7 25348397 N/A physical interaction ComPPI
TRRAP H2AZ1 25348397 N/A physical interaction ComPPI
TRRAP ZNF148 25348397 N/A physical interaction ComPPI
TRRAP TCF3 25348397 N/A physical interaction ComPPI
TRRAP TAF7 25348397 N/A physical interaction ComPPI
TRRAP MRE11 25348397 N/A physical interaction ComPPI
TRRAP DCP2 25348397 N/A physical interaction ComPPI
TRRAP SOX3 25348397 N/A physical interaction ComPPI
TRRAP OBSL1 25348397 N/A physical interaction ComPPI
TRRAP EED 25348397 N/A physical interaction ComPPI
TRRAP PLAC1 25348397 N/A physical interaction ComPPI
TRRAP FOXR1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TRRAP TADA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRRAP TADA2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRRAP H2BC1 25348397 N/A physical interaction ComPPI
TRRAP YEATS4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRRAP BTAF1 25348397 N/A physical interaction ComPPI
TRRAP VPS72 15647280 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRRAP NCBP1 25348397 N/A physical interaction ComPPI
TRRAP SUPT7L 25348397 N/A physical interaction ComPPI
TRRAP RUVBL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRRAP EPC2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRRAP SUPT20H 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
TRRAP TTI2 25348397 N/A physical interaction ComPPI
TRRAP EPC1 25348397 N/A physical interaction ComPPI
TRRAP KRT72 25348397 N/A physical interaction ComPPI
TRRAP JAZF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRRAP BRINP1 25348397 N/A physical interaction ComPPI
TRRAP GAN 25348397 N/A physical interaction ComPPI
TRRAP FOXO3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TRRAP SENP3 25348397 N/A physical interaction ComPPI
TRRAP MBTD1 25348397 N/A physical interaction ComPPI
TRRAP AURKA 25348397 N/A physical interaction ComPPI
TRRAP ATOH1 25348397 N/A physical interaction ComPPI
TRRAP MYCL 25348397 N/A physical interaction ComPPI
TRRAP MEAF6 25348397 N/A physical interaction ComPPI
TRRAP SCN3B 25348397 N/A physical interaction ComPPI
TRRAP CACNG5 25348397 N/A physical interaction ComPPI
TRRAP CREB3L1 25348397 N/A physical interaction ComPPI
TRRAP HDAC6 25348397 N/A physical interaction ComPPI
TRRAP MYCN 25348397 N/A physical interaction ComPPI
TRRAP E2F3 22157815 24234451 25348397 association pull down ComPPI,IntAct
TRRAP KDM4A 23871696 24234451 25348397 association pull down ComPPI,IntAct
TRRAP MLLT3 20203130 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TRRAP DOT1L 20203130 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
H3C1 TRRAP 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MKI67 TRRAP 24234451 26949251 association anti tag coimmunoprecipitation IntAct
CTNNB1 TRRAP 16510874 16510875 18347063 27898060 stimulant N/A OmniPath
TRRAP MYC 10611234 11511539 11839798 12660246 16705173 17145710 17314511 17353931 19818711 20194507 20946988 27898060 9708738 stimulant N/A OmniPath
RPL11 TRRAP 20194507 27898060 inhibition N/A OmniPath

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