Gene Information gene info

GENE:TUT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TUT1
FullNmae terminal uridylyl transferase 1, U6 snRNA-specific
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26184
EnsembleID ENSG00000149016
Uniprot Q9H6E5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TUT1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
TUT1 GO:0003723,GO:0003730,GO:0005515,GO:0005524,GO:0005654,GO:0005730,GO:0005739,GO:0005829,GO:0006378,GO:0006378,GO:0006378,GO:0016180,GO:0016607,GO:0016607,GO:0017070,GO:0019899,GO:0034477,GO:0046872,GO:0050265,GO:0140767,GO:1990817,GO:1990817

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YWHAE TUT1 20462248 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 TUT1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 TUT1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 TUT1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TUT1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 TUT1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 TUT1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TUT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TUT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 TUT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TUT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 TUT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000FC8EB TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000048F59D TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000F6E49 TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000148B91 TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000367985 TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000345DEB TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 TUT1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CSNK1A1 TUT1 22135298 phosphorylation N/A PhosphoSite
ATR TUT1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
PIN1 TUT1 25348397 N/A physical interaction ComPPI
SNRPF TUT1 25348397 N/A physical interaction ComPPI
SNRPG TUT1 25348397 N/A physical interaction ComPPI
LSM6 TUT1 25348397 N/A physical interaction ComPPI
HMOX1 TUT1 25348397 N/A physical interaction ComPPI
KATNBL1 TUT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
YWHAZ TUT1 20618440 24234451 25348397 association tandem affinity purification ComPPI,IntAct
YWHAQ TUT1 25348397 N/A physical interaction ComPPI
USP4 TUT1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HUWE1 TUT1 25348397 N/A physical interaction ComPPI
SOX2 TUT1 25348397 N/A physical interaction ComPPI
CDC37 TUT1 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
SART3 TUT1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LSM5 TUT1 25348397 N/A physical interaction ComPPI
CSTF2 TUT1 18288197 21102410 24234451 25348397 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
SYMPK TUT1 18288197 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PIP5K1A TUT1 18288197 24234451 25348397 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct,OmniPath
PRPF4 TUT1 19615732 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMELESS TUT1 25348397 N/A physical interaction ComPPI
CPSF4 TUT1 21102410 24234451 25348397 association pull down ComPPI,IntAct
CPSF1 TUT1 21102410 24234451 25348397 association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CPSF2 TUT1 18288197 21102410 24234451 25348397 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CPSF3 TUT1 18288197 21102410 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PRPF3 TUT1 25348397 N/A physical interaction ComPPI
SNRPE TUT1 25348397 N/A physical interaction ComPPI
SNRPN TUT1 25348397 N/A physical interaction ComPPI
IL32 TUT1 25348397 N/A physical interaction ComPPI
FBXO6 TUT1 25348397 N/A physical interaction ComPPI
SNRPGP15 TUT1 25348397 N/A physical interaction ComPPI
USP15 TUT1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRPF31 TUT1 25348397 N/A physical interaction ComPPI
YTHDF1 TUT1 25348397 N/A physical interaction ComPPI
MEPCE TUT1 25348397 N/A physical interaction ComPPI
TUT1 CENATAC 25348397 N/A physical interaction ComPPI
TUT1 LARP7 18281698 24234451 25348397 association tandem affinity purification ComPPI,IntAct
FGL1 TUT1 25348397 N/A physical interaction ComPPI
CSNK1A1 TUT1 26138484 27898060 N/A N/A OmniPath

Visualization