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GENE：U2SURP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol U2SURP
FullNmae U2 snRNP associated SURP domain containing
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30855
EnsembleID ENSG00000163714
Uniprot O15042

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
U2SURP immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
U2SURP cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
U2SURP GO:0003723,GO:0003723,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0006396

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
U2SURP hsa:23350 path:hsa03040 Spliceosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR U2SURP 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 U2SURP 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC U2SURP 12747840 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C U2SURP 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 U2SURP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA U2SURP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF U2SURP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 U2SURP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 U2SURP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 U2SURP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS U2SURP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A U2SURP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF U2SURP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000CF1D2 U2SURP 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000272A3D U2SURP 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000EED18 U2SURP 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00002075FA U2SURP 20371350 21572407 22012620 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F U2SURP 20371350 21572407 22012620 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 U2SURP 20371350 21572407 22012620 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 U2SURP 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA U2SURP 20371350 21572407 22012620 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 U2SURP 20371350 21572407 22012620 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA U2SURP 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 U2SURP 20371350 21572407 22012620 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 U2SURP 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE U2SURP 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 U2SURP 20371350 21572407 22012620 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000023133F U2SURP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 U2SURP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C U2SURP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D U2SURP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F U2SURP 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA U2SURP 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003EB4CF U2SURP 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004F24A9 U2SURP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000029D793 U2SURP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA U2SURP 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B U2SURP 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 U2SURP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E U2SURP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 U2SURP 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MFAP1 U2SURP 25348397 N/A physical interaction ComPPI
SNW1 U2SURP 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RBM17 U2SURP 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDC5L U2SURP 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CD2BP2 U2SURP 25348397 N/A physical interaction ComPPI
LMNA U2SURP 25348397 N/A physical interaction ComPPI
SF3A2 U2SURP 25348397 N/A physical interaction ComPPI
JUN U2SURP 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 U2SURP 25348397 N/A physical interaction ComPPI
FGFR2 U2SURP 25348397 N/A physical interaction ComPPI
U2AF2 U2SURP 25348397 N/A physical interaction ComPPI
PAXIP1 U2SURP 25348397 N/A physical interaction ComPPI
CUL3 U2SURP 25348397 N/A physical interaction ComPPI
NTRK1 U2SURP 25348397 N/A physical interaction ComPPI
PRPF40A U2SURP 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RPA1 U2SURP 25348397 N/A physical interaction ComPPI
MYC U2SURP 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TERT U2SURP 25348397 N/A physical interaction ComPPI
RBM10 U2SURP 22365833 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
GRK5 U2SURP 25348397 N/A physical interaction ComPPI
RPA2 U2SURP 25348397 N/A physical interaction ComPPI
RPA3 U2SURP 25348397 N/A physical interaction ComPPI
CUL1 U2SURP 25348397 N/A physical interaction ComPPI
MED9 U2SURP 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SF3A1 U2SURP 25348397 N/A physical interaction ComPPI
DROSHA U2SURP 25348397 N/A physical interaction ComPPI
GABARAP U2SURP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
WWOX U2SURP 25348397 N/A physical interaction ComPPI
MDC1 U2SURP 25348397 N/A physical interaction ComPPI
ZRSR2 U2SURP 25348397 N/A physical interaction ComPPI
SF1 U2SURP 24234451 25348397 26420826 association anti bait coimmunoprecipitation ComPPI,IntAct
CUL7 U2SURP 25348397 N/A physical interaction ComPPI
H3C1 U2SURP 25348397 N/A physical interaction ComPPI
CAND1 U2SURP 25348397 N/A physical interaction ComPPI
BARD1 U2SURP 25348397 N/A physical interaction ComPPI
ESR1 U2SURP 21182205 24234451 25348397 association cosedimentation through density gradient,physical interaction ComPPI,IntAct
TRA2A U2SURP 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TBC1D4 U2SURP 12421765 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TARDBP U2SURP 25348397 N/A physical interaction ComPPI
MED19 U2SURP 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPSA U2SURP 25348397 N/A physical interaction ComPPI
SNRPE U2SURP 25348397 N/A physical interaction ComPPI
MYO1C U2SURP 25348397 N/A physical interaction ComPPI
RPS2 U2SURP 25348397 N/A physical interaction ComPPI
CYLD U2SURP 25348397 N/A physical interaction ComPPI
CTNNBL1 U2SURP 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GABARAPL1 U2SURP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RBM5 U2SURP 22365833 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
SIRT7 U2SURP 25348397 N/A physical interaction ComPPI
DDX42 U2SURP 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLOD1 U2SURP 25348397 N/A physical interaction ComPPI
DDX41 U2SURP 24234451 25348397 25920683 association anti tag coimmunoprecipitation ComPPI,IntAct
NCL U2SURP 25348397 N/A physical interaction ComPPI
U2SURP OBSL1 25348397 N/A physical interaction ComPPI
U2SURP RPS8 25348397 N/A physical interaction ComPPI
U2SURP CHERP 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
U2SURP JMJD6 25348397 N/A physical interaction ComPPI
U2SURP DCLRE1A 24234451 30021884 physical association cross-linking study IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B7CF7 U2SURP 27087310 direct interaction,inhibition N/A NPInter

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