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GENE：UBE2D3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UBE2D3
FullNmae ubiquitin conjugating enzyme E2 D3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12476
EnsembleID ENSG00000109332
Uniprot P61077

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UBE2D3 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UBE2D3 cuproptosis 38006800 At the same time, copper is also a dynamic signaling metal and metal allosteric regulator, such as copper-dependent phosphodiesterase 3B (PDE3B) in lipolysis, mitogen-activated protein kinase kinase 1 (MEK1) in cell growth and proliferation and MEK2, the kinases ULK1 and ULK2 in autophagy. Cell proliferation that relies on copper is called copper hyperplasia, which corresponds to this article about copper death. These enzymes may have some interactions with FDX1 signaling, which may be a focus of future research. cuproptosis-related genes
UBE2D3 cuproptosis 38495196 Cuproptosis-related genes were manually curated, and differentially expressed cuproptosis-related genes (DECuGs) were identified.Then, the 16 DECuGs were obtained by the intersection of the 5018 DEGs and 63 cuproptosis-related genes. 63 cuproptosis-related genes
UBE2D3 cuproptosis 38348451 Ubiquitin-conjugating enzymes. Involved in protein degradation pathways that may be implicated in cuproptosis. CRGs in the cuproptosis pathway
UBE2D3 cuproptosis 36211378 Forty-three cuproptosis-related genes were selected from the review of Chang et al. (13) 43 cuproptosis-related genes in the study
UBE2D3 cuproptosis 36568423 Additionally, 41 cuproptosis regulators were obtained from the previous publications. cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
UBE2D3 GO:0000122,GO:0000151,GO:0000209,GO:0004842,GO:0004842,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005829,GO:0005886,GO:0006281,GO:0006511,GO:0006513,GO:0006915,GO:0010008,GO:0016567,GO:0030514,GO:0031625,GO:0036211,GO:0043161,GO:0051865,GO:0061630,GO:0061631,GO:0061631,GO:0070062,GO:0070936,GO:0070936,GO:0070979,GO:0070979,GO:0085020,GO:1903955

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UBE2D3 hsa:7323 path:hsa03083 Polycomb repressive complex - Homo sapiens (human)
UBE2D3 hsa:7323 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)
UBE2D3 hsa:7323 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)
UBE2D3 hsa:7323 path:hsa05131 Shigellosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
UBE2D3 XIAP 15749826 23180781 ubiquitination reaction ubiquitination reaction InnateDB
UBE2D3 CASP9 15749826 23180781 ubiquitination reaction ubiquitination reaction InnateDB
NFKBIA UBE2D3 10329681 23180781 ubiquitination reaction ubiquitination reaction InnateDB
RNF125 UBE2D3 17460044 23180781 physical association ubiquitination reaction InnateDB
UBE2D3 BIRC2 12525502 12867425 23180781 ubiquitination reaction,physical association anti tag coimmunoprecipitation,enzymatic study InnateDB
UBE2D3 BIRC3 12525502 23180781 ubiquitination reaction,physical association anti tag coimmunoprecipitation,enzymatic study InnateDB
UBE2D3 DIABLO 12525502 23180781 ubiquitination reaction enzymatic study InnateDB
UBE2D3 MYCBP2 18308511 23180781 physical association anti tag coimmunoprecipitation InnateDB
UBE2D3 MAVS 19881509 23180781 ubiquitination reaction enzymatic study InnateDB
UBE2D3 ITCH 19881509 23180781 ubiquitination reaction enzymatic study InnateDB
TRIM23 UBE2D3 20724660 23180781 ubiquitination reaction enzymatic study InnateDB

Source Target Pmid Interactiontype Methods Database
NFKBIA UBE2D3 20005715 interaction type N/A PSP
PRKAB1 UBE2D3 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
AR UBE2D3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 UBE2D3 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 UBE2D3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 UBE2D3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A UBE2D3 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 UBE2D3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 UBE2D3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UBE2D3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UBE2D3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UBE2D3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UBE2D3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UBE2D3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF UBE2D3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 UBE2D3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 UBE2D3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SNAI2 UBE2D3 21044962 trascriptional regulation,stimulation inferred by curator TFlink
MYC UBE2D3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 UBE2D3 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000122ED0 UBE2D3 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 UBE2D3 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000070B1D UBE2D3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BE495 UBE2D3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000204177 UBE2D3 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 UBE2D3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D UBE2D3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000077AED UBE2D3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 UBE2D3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000412AC7 UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000759EB8 UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000000C73C UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000521626 UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003BBF48 UBE2D3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 UBE2D3 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D UBE2D3 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000017EE98 UBE2D3 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 UBE2D3 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001B9F58 UBE2D3 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004505E4 UBE2D3 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004407DC UBE2D3 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000017EA6A UBE2D3 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004E008F UBE2D3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 UBE2D3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000259AE4 UBE2D3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 UBE2D3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000060AABB UBE2D3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000065D58 UBE2D3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002152A8 UBE2D3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000005CF5F UBE2D3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001DE669 UBE2D3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000045DBD UBE2D3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005F1B8C UBE2D3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002578DA UBE2D3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000008C563 UBE2D3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075BDA4 UBE2D3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003AD2AA UBE2D3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005194EC UBE2D3 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TRIM38 UBE2D3 25348397 N/A physical interaction ComPPI
UBASH3B UBE2D3 25348397 N/A physical interaction ComPPI
ISG15 UBE2D3 25348397 N/A physical interaction ComPPI
PCNA UBE2D3 25348397 N/A physical interaction ComPPI
SAT1 UBE2D3 11485561 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
TRAF6 UBE2D3 17353931 19549727 24234451 25348397 ubiquitination reaction,physical association anti bait coimmunoprecipitation,physical interaction,two hybrid array,enzymatic study ComPPI,IntAct
FBXO2 UBE2D3 25348397 N/A physical interaction ComPPI
XIAP UBE2D3 19549727 24234451 25348397 ubiquitination reaction,physical association two hybrid,physical interaction,two hybrid array,enzymatic study ComPPI,IntAct
BMI1 UBE2D3 21772249 24234451 25348397 physical association x-ray crystallography,physical interaction ComPPI,IntAct
RING1 UBE2D3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM32 UBE2D3 25348397 N/A physical interaction ComPPI
MKRN3 UBE2D3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MCM2 UBE2D3 25348397 N/A physical interaction ComPPI
PCGF2 UBE2D3 25348397 N/A physical interaction ComPPI
MARCHF5 UBE2D3 25348397 N/A physical interaction ComPPI
UBTD1 UBE2D3 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BIRC8 UBE2D3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RNF5 UBE2D3 14525934 14667819 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
UBE2D4 UBE2D3 25348397 N/A physical interaction ComPPI
RNF7 UBE2D3 25348397 N/A physical interaction ComPPI
RNF115 UBE2D3 19690564 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SMURF2 UBE2D3 25348397 N/A physical interaction ComPPI
CBL UBE2D3 25348397 N/A physical interaction ComPPI
SIAH2 UBE2D3 25348397 N/A physical interaction ComPPI
RNF111 UBE2D3 19549727 19690564 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CBLC UBE2D3 25348397 N/A physical interaction ComPPI
USP7 UBE2D3 25348397 N/A physical interaction ComPPI
KAT2B UBE2D3 25348397 N/A physical interaction ComPPI
FZR1 UBE2D3 25348397 N/A physical interaction ComPPI
NBR1 UBE2D3 25348397 N/A physical interaction ComPPI
SIAH1 UBE2D3 17420721 19250734 19549727 19690564 22483617 24234451 25348397 27898060 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct,OmniPath
WWP1 UBE2D3 25348397 N/A physical interaction ComPPI
MYBL2 UBE2D3 25348397 N/A physical interaction ComPPI
RBX1 UBE2D3 25348397 N/A physical interaction ComPPI
UBB UBE2D3 25348397 N/A molecular sieving,physical interaction,comigration in sds page ComPPI
UBC UBE2D3 16196087 17170710 21900206 24234451 24403071 24446487 25348397 27898060 N/A molecular sieving,nuclear magnetic resonance,physical interaction,comigration in sds page ComPPI,IntAct,OmniPath
RPS27A UBE2D3 25348397 N/A molecular sieving,physical interaction,comigration in sds page ComPPI
UBA52 UBE2D3 21900206 24234451 25348397 physical association two hybrid,molecular sieving,physical interaction,comigration in sds page ComPPI,IntAct
UBE2N UBE2D3 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
HERC1 UBE2D3 25348397 N/A physical interaction ComPPI
BTRC UBE2D3 25348397 N/A physical interaction ComPPI
WWP2 UBE2D3 25348397 N/A physical interaction ComPPI
POLL UBE2D3 25348397 N/A physical interaction ComPPI
POLM UBE2D3 25348397 N/A physical interaction ComPPI
NFKBIA UBE2D3 10329681 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CSNK2A1 UBE2D3 25348397 N/A physical interaction ComPPI
RPL28 UBE2D3 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
RMND5B UBE2D3 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
STAM2 UBE2D3 25348397 N/A physical interaction ComPPI
UHRF2 UBE2D3 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBR5 UBE2D3 25348397 N/A physical interaction ComPPI
TERT UBE2D3 23741361 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SQSTM1 UBE2D3 25348397 N/A physical interaction ComPPI
DAPK3 UBE2D3 18515077 25348397 27898060 N/A physical interaction ComPPI,OmniPath
RELA UBE2D3 25348397 N/A physical interaction ComPPI
RABGEF1 UBE2D3 25348397 N/A physical interaction ComPPI
UBA6 UBE2D3 25348397 N/A physical interaction ComPPI
SYVN1 UBE2D3 12646171 20237263 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MDM4 UBE2D3 25348397 N/A physical interaction ComPPI
RNF8 UBE2D3 25348397 N/A physical interaction ComPPI
RLIM UBE2D3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HUWE1 UBE2D3 25348397 N/A physical interaction ComPPI
TOPORS UBE2D3 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RNF168 UBE2D3 19500350 22373579 25348397 27898060 N/A physical interaction ComPPI,OmniPath
EPS15 UBE2D3 25348397 N/A physical interaction ComPPI
ARF6 UBE2D3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NEDD4L UBE2D3 25348397 N/A physical interaction ComPPI
RPLP1 UBE2D3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TRIM23 UBE2D3 25348397 N/A physical interaction ComPPI
NEDD8 UBE2D3 25348397 N/A physical interaction ComPPI
CUL4B UBE2D3 25348397 N/A physical interaction ComPPI
MDM2 UBE2D3 25348397 N/A physical interaction ComPPI
TUBA1A UBE2D3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
VHL UBE2D3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDC34 UBE2D3 25348397 N/A physical interaction ComPPI
TRIM63 UBE2D3 25348397 N/A physical interaction ComPPI
RNF2 UBE2D3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM28 UBE2D3 25348397 N/A physical interaction ComPPI
HDAC6 UBE2D3 25348397 N/A physical interaction ComPPI
DTX1 UBE2D3 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ITCH UBE2D3 25348397 N/A physical interaction ComPPI
DTX2 UBE2D3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RCHY1 UBE2D3 25348397 N/A physical interaction ComPPI
TRAIP UBE2D3 25348397 N/A physical interaction ComPPI
F12 UBE2D3 25348397 N/A physical interaction ComPPI
MID1 UBE2D3 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MID2 UBE2D3 25348397 N/A physical interaction ComPPI
HECW1 UBE2D3 25348397 N/A physical interaction ComPPI
HECTD1 UBE2D3 25348397 N/A physical interaction ComPPI
PRKN UBE2D3 25348397 N/A physical interaction ComPPI
PJA1 UBE2D3 25348397 N/A physical interaction ComPPI
PJA2 UBE2D3 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NEDD4 UBE2D3 14525934 21399620 24234451 25348397 9990509 N/A experimental interaction detection,surface plasmon resonance,physical interaction,in vitro,surface plasmon resonance array ComPPI,HPRD,IntAct
CADPS2 UBE2D3 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 BRCA1 12732733 14525934 16628214 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
UBE2D3 DTX3L 12670957 14525934 19549727 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo ComPPI,HPRD,IntAct
UBE2D3 TRIM39 14525934 16189514 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
UBE2D3 RNF126 16189514 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach ComPPI,IntAct
UBE2D3 NFKB1 10835356 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
UBE2D3 MEX3B 14525934 16169070 21900206 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
UBE2D3 MAGEA11 25348397 N/A physical interaction ComPPI
UBE2D3 UBE3A 14525934 25348397 9990509 N/A experimental interaction detection,physical interaction ComPPI,HPRD
UBE2D3 RBCK1 25348397 N/A physical interaction ComPPI
UBE2D3 DDX58 25348397 N/A physical interaction ComPPI
UBE2D3 RNF125 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 UFM1 25348397 N/A physical interaction ComPPI
UBE2D3 AMFR 19549727 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 CNOT4 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 UBE4A 15611659 19690564 24234451 25348397 27898060 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct,OmniPath
UBE2D3 RNF103 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RNF181 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 MAP3K1 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 MIB1 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RFWD3 19549727 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RNF11 19549727 19690564 24234451 25348397 ubiquitination reaction,physical association two hybrid,physical interaction,two hybrid array,enzymatic study ComPPI,IntAct
UBE2D3 RNF13 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RNF130 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RNF150 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RNF165 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RNF167 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RNF25 19549727 19690564 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2D3 RNF26 19549727 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RNF43 18313049 19690564 24234451 25348397 ubiquitination reaction,physical association physical interaction,two hybrid array,enzymatic study ComPPI,IntAct
UBE2D3 RNF4 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 ZNRF1 19549727 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 ZNRF2 25348397 N/A physical interaction ComPPI
UBE2D3 ZNRF4 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RNF138 25348397 N/A physical interaction ComPPI
UBE2D3 UBOX5 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 DTX3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2D3 RNF14 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RNF114 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 TRIM8 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 DZIP3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 TRIM27 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RNF10 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RNF166 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RNF185 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 BFAR 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 TRAF7 25348397 N/A physical interaction ComPPI
UBE2D3 MARCHF3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RSPRY1 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 LRSAM1 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 CHFR 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 MGRN1 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 TRIM55 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 RNF38 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 TRIM17 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 TRIM2 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 TRIM25 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 TRIM31 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 TRIM35 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D3 TRIM5 18799573 19549727 24234451 25348397 26212332 27898060 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct,OmniPath
UBE2D3 BIRC2 25348397 N/A physical interaction,physical interaction,bio-layer interferometry ComPPI
UBE2D3 BIRC3 25348397 N/A physical interaction ComPPI
UBE2D3 STUB1 11743028 19153604 19713937 19913553 20618441 20675402 20704274 20943656 21518764 21625540 22551455 23625928 23865999 24043303 25258038 25348397 26280536 27898060 N/A physical interaction ComPPI,OmniPath
UBE2D3 UBE4B 11435423 15466860 20017557 20696396 23509263 23550736 25348397 27898060 N/A isothermal titration calorimetry,nuclear magnetic resonance,x-ray crystallography,physical interaction ComPPI,OmniPath
UBE2D3 BIRC7 25348397 N/A physical interaction ComPPI
UBE2D3 DBN1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2D3 STAU1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2D3 KIAA1107 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2D3 FOCAD 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2D3 MKRN9P 25348397 N/A physical interaction ComPPI
UBE2D3 MKRN1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2D3 XPNPEP1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2D3 STK25 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2D3 PDCD5 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2D3 ELAVL1 25348397 N/A physical interaction ComPPI
UBE2D3 TRIM10 25348397 N/A physical interaction ComPPI
UBE2D3 TRIM11 25348397 N/A physical interaction ComPPI
UBE2D3 TRIM50 25348397 N/A physical interaction ComPPI
UBE2D3 TRIM3 25348397 N/A physical interaction ComPPI
UBE2D3 TRIM7 25348397 N/A physical interaction ComPPI
UBE2D3 TRIM37 25348397 N/A physical interaction ComPPI
UBE2D3 TRIM45 25348397 N/A physical interaction ComPPI
UBE2D3 UBA1 24234451 25260751 25348397 ubiquitination reaction physical interaction,ubiquitinase assay ComPPI,IntAct
UBE2D3 FBXO25 25348397 N/A physical interaction ComPPI
UBE2D3 SMURF1 25348397 N/A physical interaction ComPPI
UBE2D3 MYLIP 25348397 N/A physical interaction ComPPI
UBE2D3 TRIM33 25348397 N/A physical interaction ComPPI
UBE2D3 WSB1 25348397 N/A physical interaction ComPPI
UBE2D3 TRIM54 25348397 N/A physical interaction ComPPI
UBE2D3 RFFL 25348397 N/A physical interaction ComPPI
UBE2D3 RNF146 25348397 N/A physical interaction ComPPI
UBE2D3 RNF41 25348397 N/A physical interaction ComPPI
UBE2D3 KCTD7 25348397 N/A physical interaction ComPPI
UBE2D3 RNF220 25348397 N/A physical interaction ComPPI
UBE2D3 TRIM68 25348397 N/A physical interaction ComPPI
UBE2D3 FBXW8 25348397 N/A physical interaction ComPPI
UBE2D3 SH3RF1 25348397 N/A physical interaction ComPPI
UBE2D3 RNF122 25348397 N/A physical interaction ComPPI
UBE2D3 MARCHF8 25348397 N/A physical interaction ComPPI
UBE2D3 HERC2 25348397 N/A physical interaction ComPPI
UBE2D3 HERC2P3 25348397 N/A physical interaction ComPPI
UBE2D3 BARD1 25348397 N/A physical interaction ComPPI
UBE2D3 RNF31 25348397 N/A physical interaction ComPPI
UBE2D3 MSL2 25348397 N/A physical interaction ComPPI
UBE2D3 NHLRC1 15930137 24234451 25348397 physical association physical interaction,ubiquitinase assay ComPPI,IntAct
UBE2D3 FBXO32 25348397 N/A physical interaction ComPPI
UBE2D3 FBXL2 25348397 N/A physical interaction ComPPI
UBE2D3 AMBRA1 25348397 N/A physical interaction ComPPI
UBE2D3 MSL1 25348397 N/A physical interaction ComPPI
UBE2D3 FBXW11 25348397 N/A physical interaction ComPPI
UBE2D3 ARIH1 25348397 N/A physical interaction ComPPI
UBE2D3 MARCHF7 25348397 N/A physical interaction ComPPI
UBE2D3 PRPF19 25348397 N/A physical interaction ComPPI
UBE2D3 OTUB1 19549727 22124327 24234451 25348397 25416956 26752685 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBE2D3 DAZAP2 25348397 N/A physical interaction ComPPI
UBE2D3 MKRN2 25348397 N/A physical interaction ComPPI
UBE2D3 PHF7 25348397 N/A physical interaction ComPPI
UBE2D3 INCA1 25348397 N/A physical interaction ComPPI
UBE2D3 HECW2 25348397 N/A physical interaction ComPPI
UBE2D3 TMEM129 25348397 N/A physical interaction ComPPI
UBE2D3 UBE2C 25348397 N/A physical interaction ComPPI
UBE2D3 AREL1 25348397 N/A physical interaction ComPPI
UBE2D3 UBE3C 25348397 N/A physical interaction ComPPI
UBE2D3 FBXL12 25348397 N/A physical interaction ComPPI
UBE2D3 UHRF1 25348397 N/A physical interaction ComPPI
UBE2D3 PCGF1 25348397 N/A physical interaction ComPPI
UBE2D3 PCGF3 25348397 N/A physical interaction ComPPI
UBE2D3 PCGF5 25348397 N/A physical interaction ComPPI
UBE2D3 PCGF6 25348397 N/A physical interaction ComPPI
UBE2D3 NOSIP 25348397 N/A physical interaction ComPPI
UBE2D3 TRIM69 25348397 N/A physical interaction ComPPI
UBE2D3 RNF216 25348397 N/A physical interaction ComPPI
UBE2D3 FBXO7 25348397 N/A physical interaction ComPPI
UBE2D3 KDM1B 25348397 N/A physical interaction ComPPI
UBE2D3 UBE2S 25348397 N/A physical interaction ComPPI
UBE2D3 F3 25348397 N/A physical interaction ComPPI
UBE2D3 ANAPC11 25348397 N/A physical interaction ComPPI
UBE2D3 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
UBE2D3 GH1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
UBE2D3 PRKAB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
UBE2D3 UFL1 19690564 24234451 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
UBE2D3 SNURF 19690564 24234451 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
UBE2D3 BRIX1 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2D3 UBE2V1 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2D3 TRIM62 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ARIH2 UBE2D3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MUL1 UBE2D3 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM26 UBE2D3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM43 UBE2D3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IKBKG UBE2D3 12867425 14525934 N/A experimental interaction detection HPRD
UBE2D3 NFKB1 10835356 27898060 inhibition N/A OmniPath
UBE2D3 NFKBIA 10329681 20347421 27898060 inhibition N/A OmniPath
UBE2D3 SMAD2 10587642 27898060 stimulant N/A OmniPath
BIRC2 UBE2D3 12525502 12867425 21113135 25383668 27898060 N/A N/A OmniPath
UBE2D3 BRCA1 11927591 12438698 12732733 15367667 15886201 15905410 16628214 16818604 17283126 17349954 18369654 19712108 20351172 21113135 21531767 21532592 21756275 21965653 22863316 25355358 27898060 stimulant N/A OmniPath
BIRC3 UBE2D3 12525502 21113135 21331077 27898060 N/A N/A OmniPath
UBE2D3 RNF125 17460044 17719635 19549727 27898060 N/A N/A OmniPath
UBE2D3 SKIL 11691834 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00008B4B40 UBE2D3 27087310 direct interaction,inhibition N/A NPInter

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