Gene Information gene info

GENE:ALG2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ALG2
FullNmae ALG2 alpha-1,3/1,6-mannosyltransferase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23159
EnsembleID ENSG00000119523
Uniprot Q9H553

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ALG2 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ALG2 GO:0000033,GO:0000033,GO:0000033,GO:0004378,GO:0005515,GO:0005634,GO:0005737,GO:0005789,GO:0006486,GO:0006488,GO:0006488,GO:0006490,GO:0016020,GO:0016020,GO:0046982,GO:0048306,GO:0048306,GO:0048471,GO:0051592,GO:0102704

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ALG2 hsa:85365 path:hsa00510 N-Glycan biosynthesis - Homo sapiens (human)
ALG2 hsa:85365 path:hsa00513 Various types of N-glycan biosynthesis - Homo sapiens (human)
ALG2 hsa:85365 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR ALG2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 ALG2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 ALG2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 ALG2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ALG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ALG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ALG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ALG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000006FDD4 ALG2 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ANXA11 ALG2 25361965 interaction type N/A PTMCode2
ALG2 ANXA11 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PEF1 ALG2 12445460 12804766 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
PTK2B ALG2 25348397 N/A physical interaction ComPPI
HSP90AA1 ALG2 25348397 N/A physical interaction ComPPI
PLSCR3 ALG2 25348397 N/A physical interaction ComPPI
SRI ALG2 25348397 N/A physical interaction ComPPI
ANXA11 ALG2 11883939 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
TSG101 ALG2 25348397 N/A physical interaction ComPPI
SHISA5 ALG2 17889823 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SEC31A ALG2 25348397 N/A physical interaction ComPPI
CD79B ALG2 25348397 N/A physical interaction ComPPI
PDCD6IP ALG2 25348397 N/A physical interaction ComPPI
VPS28 ALG2 25348397 N/A physical interaction ComPPI
VPS37A ALG2 25348397 N/A physical interaction ComPPI
TGOLN2 ALG2 25348397 N/A physical interaction ComPPI
ALG2 ANXA7 25348397 N/A physical interaction ComPPI
ALG2 HSP90AA2P 25348397 N/A physical interaction ComPPI
ALG2 LAMP1 25348397 N/A physical interaction ComPPI
ALG2 HMOX2 25348397 N/A physical interaction ComPPI
PTPN23 ALG2 25348397 N/A physical interaction ComPPI
ALG2 ALG2 12445460 12804766 14525934 N/A experimental interaction detection,two hybrid HPRD

Visualization