Gene Information gene info

GENE:UQCC2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UQCC2
FullNmae ubiquinol-cytochrome c reductase complex assembly factor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21237
EnsembleID ENSG00000137288
Uniprot Q9BRT2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UQCC2 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
UQCC2 GO:0002082,GO:0005515,GO:0005739,GO:0005743,GO:0005758,GO:0005759,GO:0005759,GO:0016604,GO:0034551,GO:0034551,GO:0042645,GO:0050796,GO:0070131,GO:2001014

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 UQCC2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 UQCC2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C UQCC2 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 UQCC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UQCC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 UQCC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UQCC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UQCC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF UQCC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 UQCC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 UQCC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003CF1AD UQCC2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CHCHD2 UQCC2 25348397 N/A physical interaction ComPPI
TXN2 UQCC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDR2 UQCC2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
GRB2 UQCC2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
VHL UQCC2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HSPB1 UQCC2 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
AURKA UQCC2 25348397 N/A physical interaction ComPPI
PDK1 UQCC2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRIM25 UQCC2 25348397 N/A physical interaction ComPPI
IKBKE UQCC2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CEACAM5 UQCC2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TUBGCP2 UQCC2 25348397 N/A physical interaction ComPPI
TUBGCP4 UQCC2 25348397 N/A physical interaction ComPPI
CEP76 UQCC2 25348397 N/A physical interaction ComPPI
NDUFA4 UQCC2 25348397 N/A physical interaction ComPPI
UQCC2 COX20 25348397 N/A physical interaction ComPPI
UQCC2 TM2D2 25348397 N/A physical interaction ComPPI

Visualization