GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
BFAR |
FullNmae |
bifunctional apoptosis regulator |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:17613 |
EnsembleID |
ENSG00000103429 |
Uniprot |
Q9NZS9 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
BFAR |
necroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
BFAR |
GO:0000209,GO:0005515,GO:0005783,GO:0005789,GO:0005886,GO:0006511,GO:0006915,GO:0016020,GO:0030674,GO:0043066,GO:0043161,GO:0043161,GO:0046872,GO:0051865,GO:0061630,GO:0061630,GO:0070534,GO:0070936,GO:0089720,GO:1903895 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
ETS1 |
BFAR |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
CEBPA |
BFAR |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
BFAR |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
BFAR |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOS |
BFAR |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
MITF |
BFAR |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS0000272A3D |
BFAR |
20371350
25416803
|
mrna cleavage,inhibition |
nucleotide sequence identification |
TarBase |
URS0000122ED0 |
BFAR |
19088304
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
URS000018E72A |
BFAR |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001DABC0 |
BFAR |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000EED18 |
BFAR |
25416803
28097098
|
mrna cleavage,inhibition |
array technology |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
UBE2D1 |
BFAR |
19549727
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
BCL2L1 |
BFAR |
25348397
|
N/A |
physical interaction |
ComPPI |
UBE2D4 |
BFAR |
19549727
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
UBE2D2 |
BFAR |
19549727
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
UBC |
BFAR |
25348397
|
N/A |
physical interaction |
ComPPI |
UBE2N |
BFAR |
19549727
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
CASP8 |
BFAR |
10716992
14525934
25348397
|
N/A |
experimental interaction detection,physical interaction,in vitro,in vivo |
ComPPI,HPRD |
BCAP31 |
BFAR |
25348397
|
N/A |
physical interaction |
ComPPI |
NGFR |
BFAR |
22566094
25348397
27898060
|
N/A |
physical interaction |
ComPPI,OmniPath |
UBE2K |
BFAR |
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
CASP10 |
BFAR |
10716992
14525934
25348397
|
N/A |
experimental interaction detection,physical interaction,in vitro,in vivo |
ComPPI,HPRD |
BCL2 |
BFAR |
10716992
14525934
25348397
|
N/A |
experimental interaction detection,physical interaction,in vivo |
ComPPI,HPRD |
UBE2D3 |
BFAR |
19549727
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
TMBIM6 |
BFAR |
25348397
|
N/A |
physical interaction |
ComPPI |
HIP1 |
BFAR |
25348397
|
N/A |
physical interaction |
ComPPI |
BFAR |
UBE2W |
19549727
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
BFAR |
IFT57 |
25348397
|
N/A |
physical interaction |
ComPPI |
BFAR |
CASP8 |
10716992
11733517
27898060
|
inhibition |
N/A |
OmniPath |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00009BFA27 |
BFAR |
27087310
|
direct interaction,inhibition |
N/A |
NPInter |
Visualization