GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
BFAR |
| FullNmae |
bifunctional apoptosis regulator |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:17613 |
| EnsembleID |
ENSG00000103429 |
| Uniprot |
Q9NZS9 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| BFAR |
necroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| BFAR |
GO:0000209,GO:0005515,GO:0005783,GO:0005789,GO:0005886,GO:0006511,GO:0006915,GO:0016020,GO:0030674,GO:0043066,GO:0043161,GO:0043161,GO:0046872,GO:0051865,GO:0061630,GO:0061630,GO:0070534,GO:0070936,GO:0089720,GO:1903895 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| ETS1 |
BFAR |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| CEBPA |
BFAR |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
BFAR |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
BFAR |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOS |
BFAR |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| MITF |
BFAR |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS0000272A3D |
BFAR |
20371350
25416803
|
mrna cleavage,inhibition |
nucleotide sequence identification |
TarBase |
| URS0000122ED0 |
BFAR |
19088304
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
| URS000018E72A |
BFAR |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00001DABC0 |
BFAR |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00000EED18 |
BFAR |
25416803
28097098
|
mrna cleavage,inhibition |
array technology |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| UBE2D1 |
BFAR |
19549727
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
| BCL2L1 |
BFAR |
25348397
|
N/A |
physical interaction |
ComPPI |
| UBE2D4 |
BFAR |
19549727
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
| UBE2D2 |
BFAR |
19549727
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
| UBC |
BFAR |
25348397
|
N/A |
physical interaction |
ComPPI |
| UBE2N |
BFAR |
19549727
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
| CASP8 |
BFAR |
10716992
14525934
25348397
|
N/A |
experimental interaction detection,physical interaction,in vitro,in vivo |
ComPPI,HPRD |
| BCAP31 |
BFAR |
25348397
|
N/A |
physical interaction |
ComPPI |
| NGFR |
BFAR |
22566094
25348397
27898060
|
N/A |
physical interaction |
ComPPI,OmniPath |
| UBE2K |
BFAR |
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
| CASP10 |
BFAR |
10716992
14525934
25348397
|
N/A |
experimental interaction detection,physical interaction,in vitro,in vivo |
ComPPI,HPRD |
| BCL2 |
BFAR |
10716992
14525934
25348397
|
N/A |
experimental interaction detection,physical interaction,in vivo |
ComPPI,HPRD |
| UBE2D3 |
BFAR |
19549727
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
| TMBIM6 |
BFAR |
25348397
|
N/A |
physical interaction |
ComPPI |
| HIP1 |
BFAR |
25348397
|
N/A |
physical interaction |
ComPPI |
| BFAR |
UBE2W |
19549727
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
| BFAR |
IFT57 |
25348397
|
N/A |
physical interaction |
ComPPI |
| BFAR |
CASP8 |
10716992
11733517
27898060
|
inhibition |
N/A |
OmniPath |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS00009BFA27 |
BFAR |
27087310
|
direct interaction,inhibition |
N/A |
NPInter |
Visualization