Gene Information gene info

  1. Home

GENE：VPS45

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol VPS45
FullNmae vacuolar protein sorting 45 homolog
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14579
EnsembleID ENSG00000136631
Uniprot Q9NRW7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
VPS45 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
VPS45 GO:0000139,GO:0000139,GO:0003674,GO:0005515,GO:0005575,GO:0005794,GO:0006886,GO:0006886,GO:0008021,GO:0010008,GO:0016020,GO:0016192

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
VPS45 hsa:11311 path:hsa04144 Endocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR VPS45 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 VPS45 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 VPS45 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A VPS45 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
FOXP3 VPS45 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 VPS45 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA VPS45 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF VPS45 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 VPS45 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 VPS45 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 VPS45 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 VPS45 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS VPS45 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A VPS45 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 VPS45 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000171CD1 VPS45 18362358 rna interference,inhibition array technology miRSponge
URS0000171CD1 VPS45 18362358 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 VPS45 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000021D7C8 VPS45 23622248 23824327 25416803 mrna cleavage,inhibition clip,clash TarBase
URS00001A405B VPS45 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000157026 VPS45 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000298BA3 VPS45 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000004CA3 VPS45 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003CF1AD VPS45 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
VPS4B VPS45 25348397 N/A physical interaction ComPPI
PAX2 VPS45 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NTRK1 VPS45 25348397 N/A physical interaction ComPPI
PTPN1 VPS45 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CASP8 VPS45 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HNRNPL VPS45 25348397 N/A physical interaction ComPPI
RBSN VPS45 11062261 14525934 19931244 24234451 25348397 25416956 26344197 27898060 physical association experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct,OmniPath
RAB5A VPS45 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EEA1 VPS45 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
DAG1 VPS45 25348397 N/A physical interaction ComPPI
OCRL VPS45 24234451 25107275 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RB1CC1 VPS45 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGOLN2 VPS45 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
STX6 VPS45 25348397 N/A physical interaction ComPPI
BET1 VPS45 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
VTI1B VPS45 25348397 N/A physical interaction ComPPI
VAMP4 VPS45 25348397 N/A physical interaction ComPPI
STX16 VPS45 12110575 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
VPS45 ZNF827 25348397 N/A physical interaction ComPPI
VPS45 BCAR3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
VPS45 CEP152 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
VPS45 NINL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
IGF1R VPS45 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00009BC0F1 VPS45 27087310 direct interaction,inhibition N/A NPInter

Visualization










  Return