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GENE：YAE1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol YAE1
FullNmae YAE1 maturation factor of ABCE1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24857
EnsembleID ENSG00000241127
Uniprot Q9NRH1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
YAE1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
YAE1 GO:0005515,GO:0005634,GO:0005737,GO:0106035

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 YAE1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 YAE1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 YAE1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 YAE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA YAE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF YAE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 YAE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 YAE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 YAE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS YAE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A YAE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 YAE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 YAE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004F859B YAE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 YAE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000032EF64 YAE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000237CBD YAE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D YAE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000000B1C9 YAE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000A07C1 YAE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 YAE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 YAE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 YAE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 YAE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D YAE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000060AABB YAE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005F1B8C YAE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002B7450 YAE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 YAE1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004959F4 YAE1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 YAE1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000012A1DD YAE1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000008DA94 YAE1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000042B108 YAE1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001B0D1E YAE1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000277201 YAE1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000259AE4 YAE1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A3D YAE1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000076995 YAE1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002E0524 YAE1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000023BE29 YAE1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000086A4D YAE1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000475586 YAE1 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CIAO1 YAE1 25348397 N/A physical interaction ComPPI
VIM YAE1 14525934 16169070 21900206 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GABARAPL2 YAE1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MAP1LC3B YAE1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
COPS5 YAE1 25348397 N/A physical interaction ComPPI
CUL3 YAE1 25348397 N/A physical interaction ComPPI
XPO1 YAE1 25348397 N/A physical interaction ComPPI
ABCE1 YAE1 25348397 N/A physical interaction ComPPI
HNRNPA2B1 YAE1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CUL2 YAE1 25348397 N/A physical interaction ComPPI
TPD52L1 YAE1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GABARAP YAE1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MAP1LC3A YAE1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CRMP1 YAE1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SERPINA4 YAE1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GABARAPL1 YAE1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
YAE1 CHD3 14525934 16169070 21900206 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
YAE1 APP 25348397 N/A physical interaction ComPPI

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