GENE：YEATS2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | YEATS2 |
| FullNmae | YEATS domain containing 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:25489 |
| EnsembleID | ENSG00000163872 |
| Uniprot | Q9ULM3 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| YEATS2 | cuproptosis | 36010978 | Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. | Cuproptosis-related genes |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| YEATS2 | GO:0000122,GO:0003714,GO:0005515,GO:0005654,GO:0006338,GO:0006355,GO:0006355,GO:0006357,GO:0006357,GO:0006357,GO:0016573,GO:0017025,GO:0035267,GO:0042393,GO:0042393,GO:0045995,GO:0045995,GO:0051302,GO:0051302,GO:0051726,GO:0051726,GO:0072686,GO:0090043,GO:0090043,GO:0140030,GO:0140566,GO:0140672,GO:0140672,GO:0140672 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | YEATS2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | YEATS2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | YEATS2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | YEATS2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| TFAP2C | YEATS2 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | YEATS2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | YEATS2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | YEATS2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | YEATS2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | YEATS2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | YEATS2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | YEATS2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | YEATS2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | YEATS2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000005D4F5 | YEATS2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000451A1 | YEATS2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000324096 | YEATS2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000016914 | YEATS2 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000338542 | YEATS2 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PSMC3 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| POLE4 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| DR1 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| POLE3 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| RAD21 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| TXNIP | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| TBP | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| KAT2B | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| TADA3 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| LMO2 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| CDK2 | YEATS2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| KAT2A | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| MAP3K7 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| CDK8 | YEATS2 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| MBIP | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| PSME3 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| UBAP2L | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| SNRNP200 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| CARD8 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| IL17RA | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| CAT | YEATS2 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| WDR5 | YEATS2 | 24234451 25348397 27705803 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| CDC23 | YEATS2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CBY2 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| POU5F1 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| NXF1 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
| NANOG | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |