Gene Information gene info

  1. Home

GENE：IFNG

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IFNG
FullNmae interferon gamma
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5438
EnsembleID ENSG00000111537
Uniprot P01579

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IFNG necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IFNG necroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
IFNG immunogenic 37275552 To identify genes associated with ICD, we collected 34 ICD-related genes from previously reported literature. retulator signature
IFNG ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IFNG autophagy 25426782 Actually, blockage of Mtb-Ag-induced IFNG markedly reduced autophagy in HR patients whereas addition of limited amounts of IFNG significantly increased autophagy in LR patients. retulator signature
IFNG autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
IFNG apoptosis 25619828 In vitro, knockdown endogenous or IFNg-induced Irgm1 significantly decreases the proliferation and increases apoptosis of B16 cells. retulator signature
IFNG apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
IFNG GO:0000122,GO:0001774,GO:0001774,GO:0001819,GO:0002250,GO:0002281,GO:0005125,GO:0005125,GO:0005133,GO:0005515,GO:0005576,GO:0005576,GO:0005615,GO:0005615,GO:0006915,GO:0006959,GO:0007166,GO:0007259,GO:0008284,GO:0009615,GO:0010508,GO:0010628,GO:0010628,GO:0010628,GO:0010628,GO:0010628,GO:0010629,GO:0010629,GO:0010634,GO:0030225,GO:0030857,GO:0031334,GO:0032700,GO:0032722,GO:0032731,GO:0032735,GO:0032747,GO:0032755,GO:0032760,GO:0032834,GO:0033141,GO:0033141,GO:0034393,GO:0038196,GO:0042307,GO:0042531,GO:0045348,GO:0045429,GO:0045672,GO:0045821,GO:0045892,GO:0048143,GO:0048143,GO:0048662,GO:0050729,GO:0050766,GO:0050769,GO:0050796,GO:0051044,GO:0051173,GO:0051607,GO:0051712,GO:0051770,GO:0060333,GO:0060333,GO:0060550,GO:0060552,GO:0060557,GO:0060559,GO:0071902,GO:0090312,GO:0097191,GO:0098586,GO:0150076,GO:1900222,GO:1901857,GO:1902004,GO:1902004,GO:1902948,GO:1903078,GO:1903543,GO:1904440,GO:1904783,GO:1904798,GO:2000273,GO:2000309

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IFNG hsa:3458 path:hsa03050 Proteasome - Homo sapiens (human)
IFNG hsa:3458 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
IFNG hsa:3458 path:hsa04066 HIF-1 signaling pathway - Homo sapiens (human)
IFNG hsa:3458 path:hsa04217 Necroptosis - Homo sapiens (human)
IFNG hsa:3458 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)
IFNG hsa:3458 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)
IFNG hsa:3458 path:hsa04612 Antigen processing and presentation - Homo sapiens (human)
IFNG hsa:3458 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)
IFNG hsa:3458 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
IFNG hsa:3458 path:hsa04657 IL-17 signaling pathway - Homo sapiens (human)
IFNG hsa:3458 path:hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human)
IFNG hsa:3458 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
IFNG hsa:3458 path:hsa04660 T cell receptor signaling pathway - Homo sapiens (human)
IFNG hsa:3458 path:hsa04940 Type I diabetes mellitus - Homo sapiens (human)
IFNG hsa:3458 path:hsa05140 Leishmaniasis - Homo sapiens (human)
IFNG hsa:3458 path:hsa05142 Chagas disease - Homo sapiens (human)
IFNG hsa:3458 path:hsa05143 African trypanosomiasis - Homo sapiens (human)
IFNG hsa:3458 path:hsa05144 Malaria - Homo sapiens (human)
IFNG hsa:3458 path:hsa05145 Toxoplasmosis - Homo sapiens (human)
IFNG hsa:3458 path:hsa05146 Amoebiasis - Homo sapiens (human)
IFNG hsa:3458 path:hsa05152 Tuberculosis - Homo sapiens (human)
IFNG hsa:3458 path:hsa05160 Hepatitis C - Homo sapiens (human)
IFNG hsa:3458 path:hsa05164 Influenza A - Homo sapiens (human)
IFNG hsa:3458 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
IFNG hsa:3458 path:hsa05200 Pathways in cancer - Homo sapiens (human)
IFNG hsa:3458 path:hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human)
IFNG hsa:3458 path:hsa05321 Inflammatory bowel disease - Homo sapiens (human)
IFNG hsa:3458 path:hsa05322 Systemic lupus erythematosus - Homo sapiens (human)
IFNG hsa:3458 path:hsa05323 Rheumatoid arthritis - Homo sapiens (human)
IFNG hsa:3458 path:hsa05330 Allograft rejection - Homo sapiens (human)
IFNG hsa:3458 path:hsa05332 Graft-versus-host disease - Homo sapiens (human)
IFNG hsa:3458 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IFNG IFNGR1 10485906 10986460 11250200 11489965 11579131 11777960 11867689 11870632 11964313 12165521 12413632 12438563 12811837 12818165 12915721 1396683 14607900 14610620 15143187 15530433 15634932 15778339 15811952 15814715 16237089 16286920 16424049 16467876 16713974 17016554 17559085 17683974 1825141 18272812 18591661 18988627 19833085 20038811 20304997 20406969 20819927 21149606 21411734 21840487 23180781 23331499 24091328 24658051 26192618 26755705 27216177 29145629 2965306 6425450 7510216 7512720 7514165 7521688 7615558 7617032 7673114 8550631 8631301 9111318 9834059 9864217 interaction type,stimulation,physical association cross-linking study,nuclear magnetic resonance,inferred by curator ACSN,InnateDB,Reactome,SignaLink,SignaLink
IFNG IFNGR2 10485906 10986460 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12438563 12811837 12818165 12915721 1396683 14607900 14610620 15143187 15530433 15634932 15778339 15811952 15814715 16237089 16286920 16424049 16467876 16713974 17016554 17559085 17683974 1825141 18272812 18591661 18988627 19833085 20038811 20304997 20406969 20819927 21149606 21411734 21840487 23331499 24091328 24658051 26192618 26755705 27216177 29145629 2965306 6425450 7510216 7512720 7514165 7521688 7615558 7617032 7673114 8550631 8631301 9111318 9834059 9864217 interaction type,stimulation,physical association inferred by curator ACSN,Reactome,SignaLink,SignaLink
JAK1 IFNG 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26192618 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217 interaction type N/A ACSN
JAK2 IFNG 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26192618 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217 interaction type N/A ACSN
IFNG FOXP3 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26192618 26755705 2965306 6425450 9834059 9864217 interaction type N/A ACSN
TXK IFNG 10523612 11406363 26192618 interaction type N/A ACSN
KLRG1 IFNG 10358138 11447289 11449354 11572860 11884419 12138178 1238444 12393695 12421919 12707331 15169881 15240681 15699106 15713798 16204085 16424155 16461340 17307799 17617594 19406987 19479342 19833085 20363967 20435894 21469115 22483603 22683124 22955274 26192618 27557510 9751747 interaction type N/A ACSN
PTPN11 IFNG 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26192618 26667266 26755705 27474009 8976179 8986721 9751747 9765283 interaction type N/A ACSN
ADORA2A IFNG 17371980 17909080 18758473 26192618 interaction type N/A ACSN
CD2 IFNG 19398758 19494291 26192618 26794910 interaction type N/A ACSN
CD96 IFNG 1313846 17971293 22285893 24658051 26192618 26787820 27620276 interaction type N/A ACSN
CD226 IFNG 10591186 12913096 14676297 19029380 22285893 24337740 24658051 26192618 26552706 26840537 28893624 8673704 interaction type N/A ACSN
TIGIT IFNG 22285893 22427644 25866972 26192618 26755705 26763253 27620276 28893624 interaction type N/A ACSN
CRTAM IFNG 15811952 22285893 26192618 26694968 interaction type N/A ACSN
SCRIB IFNG 15811952 22285893 26192618 26694968 interaction type N/A ACSN
PTPN6 IFNG 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26192618 26667266 26755705 27474009 8976179 8986721 9751747 9765283 interaction type N/A ACSN
FYN IFNG 10591186 10648627 12218089 12731048 16286920 19290918 19909365 20814939 20819927 21378271 22437870 22683124 22863785 24440149 26192618 27192565 28900677 9738502 interaction type N/A ACSN
HAVCR2 IFNG 10591186 10648627 12218089 12731048 16286920 19290918 19909365 20814939 20819927 21378271 22437870 22683124 22863785 24440149 26192618 27192565 28900677 9738502 interaction type N/A ACSN
IFNG EP300 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26192618 26755705 2965306 6425450 9834059 9864217 interaction type N/A ACSN
IFNG STAT1 10485906 10754326 10820262 10952726 11134049 11399519 11449378 11489965 11579131 11777960 11830590 11870632 11875494 11964313 11972023 12040185 12193701 12223527 12413632 12433365 12796776 12811837 12818165 12907458 12967644 14607900 14607933 14660645 14764699 15322115 15465827 15634932 15644117 15699106 15778339 15811952 15814715 16127449 16286920 16424049 16713974 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 1825141 18272812 18345002 19833085 19879327 20038811 20819927 21097505 21149606 21263073 21411734 21930765 23180781 23390297 24658051 25960930 26192618 26755705 29145629 2965306 6357187 6425450 7594497 7657660 7690989 7796299 8156998 8631301 8683106 8871614 9834059 9864217 interaction type,physical association inferred by curator,electrophoretic mobility supershift assay ACSN,InnateDB,Reactome
IFNG IL10 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26192618 26755705 2965306 6425450 9834059 9864217 interaction type N/A ACSN
IFNG TLR2 10485906 11489965 11579131 11672593 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16267105 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26192618 26755705 2965306 6425450 9834059 9864217 interaction type N/A ACSN
IFNG TLR4 10485906 11489965 11579131 11672593 11777960 11870632 11964313 12032143 12413632 12811837 12818165 14607900 15634932 15644117 15778339 15811952 15814715 16286920 16306937 16424049 16713974 16917499 17016554 17114424 17559085 1825141 18272812 19833085 20038811 20154735 20547845 20819927 21149606 21411734 23508573 24658051 26192618 26755705 2965306 6425450 9834059 9864217 interaction type N/A ACSN
IFNG LY96 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26192618 26755705 2965306 6425450 9834059 9864217 interaction type N/A ACSN
IFNG MYD88 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26192618 26755705 2965306 6425450 9834059 9864217 interaction type N/A ACSN
STAT3 IFNG 10347215 12223527 14607900 14670306 15218058 15356132 15573129 16418395 18776941 19380816 20093776 20237412 20406969 20581311 21115385 21840487 23124025 23454751 23953057 24857661 26192618 27216177 28186502 7543512 interaction type N/A ACSN
TBX21 IFNG 10761931 12055627 12802010 14614857 15084276 16410834 17440449 18768831 23180781 23232398 26192618 26885856 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
SMAD2 IFNG 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 21042762 21614932 22331441 23390297 26192618 6357187 8871614 9389648 9670020 interaction type N/A ACSN
SMAD4 IFNG 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 18768831 21042762 21614932 22331441 23390297 26192618 6357187 8515656 8871614 9389648 interaction type N/A ACSN
SMAD3 IFNG 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 18768831 21042762 21614932 22331441 23390297 26192618 6357187 8515656 8871614 9389648 interaction type N/A ACSN
IL4 IFNG 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 26192618 2965306 9834059 interaction type N/A ACSN
NFKBIZ IFNG 20876105 21224476 26192618 interaction type N/A ACSN
STAT4 IFNG 10807786 10961885 11449378 12372421 26192618 8683106 8700208 9715265 interaction type N/A ACSN
RUNX1 IFNG 15084276 18003603 26192618 interaction type N/A ACSN
IFNG HIF1A 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26192618 26755705 2965306 6425450 9834059 9864217 interaction type N/A ACSN
IFNG MIF 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26192618 26755705 2965306 6425450 9834059 9864217 interaction type N/A ACSN
CDH1 IFNG 11884419 16424155 16461340 17307799 17617594 26192618 interaction type N/A ACSN
CDH2 IFNG 11884419 16424155 16461340 17307799 17617594 26192618 interaction type N/A ACSN
CDH4 IFNG 11884419 16424155 16461340 17307799 17617594 26192618 interaction type N/A ACSN
HLA-C IFNG 11513144 21339333 26192618 9605119 interaction type N/A ACSN
KIR2DL2 IFNG 11513144 21339333 26192618 9605119 interaction type N/A ACSN
CLEC2B IFNG 11265639 12731048 12740575 15972651 17057721 20663776 20814939 21149606 23609447 26192618 interaction type N/A ACSN
KIR2DS2 IFNG 11015446 12731048 20814939 23715743 24586048 26192618 9490415 9625766 9655483 interaction type N/A ACSN
KIR3DS1 IFNG 12731048 17202323 23715743 24586048 26192618 9625766 interaction type N/A ACSN
FCER1G IFNG 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 26192618 9625766 9751747 interaction type N/A ACSN
HLA-G IFNG 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 26192618 9625766 9751747 interaction type N/A ACSN
KIR2DL4 IFNG 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 26192618 9625766 9751747 interaction type N/A ACSN
TICAM1 IFNG 11672593 11964313 12032143 12811837 15644117 16306937 16917499 17114424 20154735 20547845 23508573 26192618 interaction type N/A ACSN
DEPTOR IFNG 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19143636 19446321 19568798 19706736 19864431 20805416 21157483 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
MLST8 IFNG 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19143636 19446321 19568798 19706736 19864431 20805416 21157483 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
MTOR IFNG 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19143636 19446321 19568798 19706736 19864431 20805416 21157483 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
RPTOR IFNG 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19143636 19446321 19568798 19706736 19864431 20805416 21157483 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
IFNG ICAM1 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26192618 26755705 2965306 6425450 9834059 9864217 interaction type N/A ACSN
SOCS1 IFNG 10485906 12193701 12223527 12811837 21469115 23124025 26192618 interaction type N/A ACSN
IFNG HMGB1 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26192618 26755705 2965306 6425450 9834059 9864217 interaction type N/A ACSN
IFNG IL18R1 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26192618 26755705 2965306 6425450 9834059 9864217 interaction type N/A ACSN
IFNG IL18RAP 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26192618 26755705 2965306 6425450 9834059 9864217 interaction type N/A ACSN
IFNG RELA 10485906 10679398 11489965 11579131 11777960 11870632 11964313 12133954 12413632 12759422 12818165 14607900 14668329 15079071 15536066 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17145890 17404308 17550372 17559085 1825141 18272812 19171876 19833085 20038811 20138012 20819927 21149606 21224476 21411734 23180781 23430059 24658051 26192618 26755705 2965306 6425450 7623820 8383323 8580069 8641346 9743347 9834059 9864217 interaction type,physical association electrophoretic mobility supershift assay ACSN,InnateDB
IFNG STAT4 11449378 15522880 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IFNG STAT3 15522880 23180781 physical association anti tag coimmunoprecipitation InnateDB
IFNG JUN 15522880 18641343 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation InnateDB
IFNG PROX1 19160541 23180781 physical association anti tag coimmunoprecipitation InnateDB
IFNG CREB1 15879136 18641343 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
EP300 IFNG 15286281 23180781 physical association anti tag coimmunoprecipitation InnateDB
CTCF IFNG 19818655 23180781 physical association anti tag coimmunoprecipitation InnateDB
IFNG ATF2 18641343 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
ATF1 IFNG 18641343 23180781 physical association electrophoretic mobility supershift assay InnateDB
IFNGR2 IFNG 23180781 7673114 physical association cross-linking study InnateDB
IRF1 IFNG 16785527 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IDO1 IFNG 16785527 23180781 physical association anti tag coimmunoprecipitation InnateDB
IFNG CREM 23180781 9545284 physical association electrophoretic mobility supershift assay InnateDB
IFNG NFKBIZ 21224476 23180781 physical association anti tag coimmunoprecipitation InnateDB
GATA3 IFNG 23180781 23232398 physical association anti tag coimmunoprecipitation InnateDB
PHF11 IFNG 20421878 23180781 physical association anti tag coimmunoprecipitation InnateDB
IFNG IFNG 1902591 29145629 physical association inferred by curator Reactome
IFNG JAK1 10986460 12438563 12915721 1396683 15143187 15530433 16237089 16467876 18591661 20304997 29145629 7510216 7514165 7615558 7617032 7673114 8550631 8631301 9111318 physical association inferred by curator Reactome
IFNG PTPN1 24243840 29145629 dephosphorylation reaction inferred by curator Reactome
IFNG PTPN6 24243840 29145629 dephosphorylation reaction inferred by curator Reactome
IFNG PRKCD 11972023 15322115 29145629 enzymatic reaction inferred by curator Reactome

Source Target Pmid Interactiontype Methods Database
CREB1 IFNG 11907114 15879136 18641343 20006311 20685939 7759501 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
ATF2 IFNG 12836278 18641343 20006311 20304822 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
ETS1 IFNG 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 IFNG 21507199 8228802 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
JUN IFNG 12626576 12836278 18641343 20006311 20304822 7759501 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
NFKB1 IFNG 17407192 18690006 21243522 9374532 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
REL IFNG 1542667 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
RELA IFNG 17407192 18690006 21243522 9374532 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
FOXP3 IFNG 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 IFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF IFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 IFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 IFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 IFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ATF3 IFNG 20304822 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 IFNG 8900159 trascriptional regulation,stimulation inferred by curator TFlink
EOMES IFNG 20056084 trascriptional regulation,stimulation inferred by curator TFlink
EP300 IFNG 12836278 trascriptional regulation,stimulation inferred by curator TFlink
GATA1 IFNG 12836278 trascriptional regulation,stimulation inferred by curator TFlink
IRF1 IFNG 13678429 trascriptional regulation,stimulation inferred by curator TFlink
MSC IFNG 19561533 trascriptional regulation,stimulation inferred by curator TFlink
MYCN IFNG 9570357 trascriptional regulation,stimulation inferred by curator TFlink
NFATC1 IFNG 12836278 trascriptional regulation,stimulation inferred by curator TFlink
NFATC2 IFNG 12836278 trascriptional regulation,stimulation inferred by curator TFlink
NFIL3 IFNG 7565758 trascriptional regulation,stimulation inferred by curator TFlink
PARP1 IFNG 17177976 trascriptional regulation,stimulation inferred by curator TFlink
PROX1 IFNG 20064070 trascriptional regulation,stimulation inferred by curator TFlink
RFX5 IFNG 12968017 trascriptional regulation,stimulation inferred by curator TFlink
STAT1 IFNG 13678429 15055356 16195385 18616672 20004484 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 IFNG 18616672 trascriptional regulation,stimulation inferred by curator TFlink
STAT4 IFNG 9558063 9642277 trascriptional regulation,stimulation inferred by curator TFlink
STAT5A IFNG 15528362 trascriptional regulation,stimulation inferred by curator TFlink
STAT5B IFNG 15528362 trascriptional regulation,stimulation inferred by curator TFlink
TBX21 IFNG 12938094 16498264 16737784 17541280 17705132 19348920 19879772 20056084 20977921 21507199 21540308 22521571 24752800 trascriptional regulation,stimulation inferred by curator TFlink
TFAP4 IFNG 12836278 trascriptional regulation,stimulation inferred by curator TFlink
USF1 IFNG 8900159 trascriptional regulation,stimulation inferred by curator TFlink
YY1 IFNG 12836278 8756632 trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A IFNG N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000171CD1 IFNG 22379033 rna interference,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000041CB9C IFNG 22379033 rna interference,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000081E1F IFNG 23360331 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000171CD1 IFNG 22379033 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000041CB9C IFNG 22379033 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000081E1F IFNG 23360331 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000003ABC4 IFNG 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00001F0C23 IFNG 24759737 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr TarBase
URS00001B341F IFNG 24725595 25416803 mrna cleavage,inhibition western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
IFNG IFNGR2 25361965 interaction type N/A PTMCode2
IFNGR2 IFNG 25361965 interaction type N/A PTMCode2
IFNG IFNGR1 25361965 interaction type N/A PTMCode2
IFNGR1 IFNG 25361965 interaction type N/A PTMCode2
IFNG TNF 25361965 interaction type N/A PTMCode2
TNF IFNG 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PDIA3 IFNG 14525934 25348397 27898060 8974399 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
IFNGR1 IFNG 10986460 11250200 12165521 14525934 24234451 25348397 7617032 N/A experimental interaction detection,x-ray crystallography,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
IFNGR2 IFNG 14525934 25348397 7673114 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
IFNG TNF 14525934 25348397 3139842 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
IFNG STAT6 25348397 N/A physical interaction ComPPI
IFNG GOPC 25348397 N/A physical interaction ComPPI
IFNG IFNG 10860730 14525934 N/A experimental interaction detection HPRD
RUNX1 IFNG 17377532 24234451 association chromatin immunoprecipitation assay IntAct
FOXP3 IFNG 23543754 24234451 association chromatin immunoprecipitation assay IntAct
TRIM28 IFNG 23543754 24234451 association chromatin immunoprecipitation assay IntAct
IFNG IFNGR1 10811850 10860730 10986460 11250200 12165521 12438563 16110316 23898330 27898060 7617032 7673114 stimulant N/A OmniPath
IFNGR1 IFNG 10860730 10986460 11250200 12165521 27898060 7617032 7673114 N/A N/A OmniPath
IFNG PSME1 27898060 8051173 N/A N/A OmniPath
IFNG IFNGR2 10811850 12438563 27898060 7673114 stimulant N/A OmniPath
IFNGR2 IFNG 27898060 7673114 N/A N/A OmniPath
IFNG PSME2 27898060 8051173 N/A N/A OmniPath
IFNG PSMB8 27898060 8811196 N/A N/A OmniPath
IFNG PSMB9 27898060 8811196 N/A N/A OmniPath
IFNG PSMB10 27898060 8811196 stimulant N/A OmniPath

Visualization










  Return