GENE：IFNAR1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | IFNAR1 |
| FullNmae | interferon alpha and beta receptor subunit 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:5432 |
| EnsembleID | ENSG00000142166 |
| Uniprot | P17181 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| IFNAR1 | necroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| IFNAR1 | necroptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
| IFNAR1 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| IFNAR1 | GO:0004905,GO:0004905,GO:0004905,GO:0005515,GO:0005764,GO:0005770,GO:0005886,GO:0005886,GO:0005886,GO:0007259,GO:0008269,GO:0008269,GO:0009615,GO:0019955,GO:0019962,GO:0032496,GO:0035457,GO:0035458,GO:0046425,GO:0060337,GO:0060337,GO:0060337,GO:0098586,GO:1901857 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| IFNAR1 | hsa:3454 | path:hsa04060 | Cytokine-cytokine receptor interaction - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa04151 | PI3K-Akt signaling pathway - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa04217 | Necroptosis - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa04380 | Osteoclast differentiation - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa04620 | Toll-like receptor signaling pathway - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa04621 | NOD-like receptor signaling pathway - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa04630 | JAK-STAT signaling pathway - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa04650 | Natural killer cell mediated cytotoxicity - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa05160 | Hepatitis C - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa05161 | Hepatitis B - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa05162 | Measles - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa05164 | Influenza A - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa05165 | Human papillomavirus infection - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa05167 | Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa05168 | Herpes simplex virus 1 infection - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa05169 | Epstein-Barr virus infection - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa05171 | Coronavirus disease - COVID-19 - Homo sapiens (human) |
| IFNAR1 | hsa:3454 | path:hsa05200 | Pathways in cancer - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| IFNAR2 | IFNAR1 | 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21854986 21930765 21930769 23180781 26192618 7512720 7521688 7543512 | interaction type,physical association | x-ray crystallography | ACSN,InnateDB |
| JAK1 | IFNAR1 | 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 26192618 7512720 7521688 7543512 | interaction type | N/A | ACSN |
| TYK2 | IFNAR1 | 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 26192618 7512720 7521688 7543512 | interaction type | N/A | ACSN |
| IFNAR1 | STAT1 | 10582086 10982844 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 23331499 24243840 26192618 29145629 7512720 7521688 7543512 8232552 | interaction type,stimulation,physical association | inferred by curator | ACSN,Reactome,SignaLink,SignaLink |
| IFNAR1 | IL15 | 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 26192618 7512720 7521688 7523571 7543512 | interaction type | N/A | ACSN |
| IFNAR1 | IL15RA | 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 26192618 7512720 7521688 7523571 7543512 | interaction type | N/A | ACSN |
| IFNAR1 | TYK2 | 14647450 15120645 15337770 23180781 23331499 24243840 29145629 7559568 8524272 8605876 8702790 9461596 9733772 | phosphorylation reaction,stimulation,physical association | anti tag coimmunoprecipitation,gst pull down,pull down,inferred by curator,in-gel kinase assay | InnateDB,Reactome,SignaLink,SignaLink |
| IFNAR1 | JAK1 | 10022928 10542297 10982844 11694501 15120645 15312780 15449939 16171819 16987978 17351669 17969444 18508557 23180781 23331499 24243840 29145629 7526154 8197134 8232552 8524272 8605876 8621447 8702790 8943354 9334213 | stimulation,physical association | gst pull down,inferred by curator | InnateDB,Reactome,SignaLink,SignaLink |
| IFNAR1 | PTPN6 | 18508557 23180781 29145629 8524272 8943354 | dephosphorylation reaction,physical association | anti tag coimmunoprecipitation,gst pull down,inferred by curator | InnateDB,Reactome |
| IFNAR1 | STAT6 | 10490982 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| IFNAR1 | STAT3 | 23180781 8626489 | physical association | gst pull down | InnateDB |
| IFNAR1 | STAT2 | 10022928 10542297 10582086 10982844 11694501 12220192 15312780 15449939 16171819 16987978 17351669 17969444 18508557 23180781 23331499 24243840 29145629 7526154 8197134 8232552 8605876 8621447 8702790 8943354 9334213 | interaction type,physical association | affinity chromatography technology,gst pull down,inferred by curator | InnateDB,Reactome,SignaLink,SignaLink |
| IFNAR1 | TRAF2 | 18362156 23180781 | physical association | anti tag coimmunoprecipitation,pull down | InnateDB |
| IFNAR1 | FBXW11 | 14532120 15337770 18056411 23180781 | ubiquitination reaction,physical association | anti tag coimmunoprecipitation,pull down,enzymatic study | InnateDB |
| IFNAR1 | CDC34 | 14532120 23180781 | ubiquitination reaction | enzymatic study | InnateDB |
| IFNAR1 | AP2M1 | 18056411 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| IFNAR1 | PRMT1 | 23180781 9029147 | physical association | anti tag coimmunoprecipitation,two hybrid | InnateDB |
| IFNAR1 | MAPK14 | 21695243 23180781 | phosphorylation reaction | protein kinase assay | InnateDB |
| IFNAR1 | PTPN1 | 11694501 29145629 | dephosphorylation reaction | inferred by curator | Reactome |
| IFNA1 | IFNAR1 | 23331499 8181059 | stimulation | N/A | SignaLink,SignaLink |
| IFNB1 | IFNAR1 | 1834641 18988627 23331499 8181059 | stimulation | N/A | SignaLink,SignaLink |
| IFNK | IFNAR1 | 17208301 23331499 | stimulation | N/A | SignaLink |
| IL36G | IFNAR1 | 17208301 23331499 | stimulation | N/A | SignaLink |
| IFNAR1 | IFNGR1 | 18929502 23331499 | stimulation | N/A | SignaLink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | IFNAR1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | IFNAR1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | IFNAR1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TP73 | IFNAR1 | 21245298 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | IFNAR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | IFNAR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | IFNAR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | IFNAR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | IFNAR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | IFNAR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | IFNAR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | IFNAR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | IFNAR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PARP1 | IFNAR1 | 19501422 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| STAT3 | IFNAR1 | 18550668 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ATF1 | IFNAR1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ESR1 | IFNAR1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| JUN | IFNAR1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MYC | IFNAR1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| POU3F1 | IFNAR1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| POU3F2 | IFNAR1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000122ED0 | IFNAR1 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00002075FA | IFNAR1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | IFNAR1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DDD35 | IFNAR1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000600E6 | IFNAR1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | IFNAR1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | IFNAR1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004719AB | IFNAR1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000052EA98 | IFNAR1 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002233F4 | IFNAR1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD002 | IFNAR1 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FFA8C | IFNAR1 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | IFNAR1 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | IFNAR1 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000527B00 | IFNAR1 | 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000032835F | IFNAR1 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000939AF | IFNAR1 | 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003D5391 | IFNAR1 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AAAFF | IFNAR1 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005ACA7C | IFNAR1 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000427B68 | IFNAR1 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000450F92 | IFNAR1 | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004CCA62 | IFNAR1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000411752 | IFNAR1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000753AD | IFNAR1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005FDCD1 | IFNAR1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000011DF | IFNAR1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E780 | IFNAR1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032FC1A | IFNAR1 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000486E0B | IFNAR1 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000047A67D | IFNAR1 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F4AC3 | IFNAR1 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5BAA | IFNAR1 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AA464 | IFNAR1 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000221168 | IFNAR1 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E226A | IFNAR1 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000020579D | IFNAR1 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000913AC | IFNAR1 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000003575B | IFNAR1 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000076995 | IFNAR1 | 25416803 27569280 | mrna cleavage,inhibition | western blot,miRNA interference luciferase reporter assay | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TYK2 | IFNAR1 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
| MAPK14 | IFNAR1 | 22135298 | phosphorylation | N/A | PhosphoSite |
| CSNK1A1 | IFNAR1 | 22135298 | phosphorylation | N/A | PhosphoSite |
| FBXW11 | IFNAR1 | 25361965 | interaction type | N/A | PTMCode2 |
| IFNAR1 | FBXW11 | 25361965 | interaction type | N/A | PTMCode2 |
| STAT3 | IFNAR1 | 25361965 | interaction type | N/A | PTMCode2 |
| IFNAR1 | STAT3 | 25361965 | interaction type | N/A | PTMCode2 |
| IFNAR1 | TYK2 | 25361965 | interaction type | N/A | PTMCode2 |
| IFNAR1 | IFNA1 | 25361965 | interaction type | N/A | PTMCode2 |
| IFNA1 | IFNAR1 | 25361965 | interaction type | N/A | PTMCode2 |
| IFNAR1 | AP2M1 | 25361965 | interaction type | N/A | PTMCode2 |
| AP2M1 | IFNAR1 | 25361965 | interaction type | N/A | PTMCode2 |
| IFNAR1 | AXL | 25361965 | interaction type | N/A | PTMCode2 |
| AXL | IFNAR1 | 25361965 | interaction type | N/A | PTMCode2 |
| IFNAR1 | JAK1 | 25361965 | interaction type | N/A | PTMCode2 |
| JAK1 | IFNAR1 | 25361965 | interaction type | N/A | PTMCode2 |
| IFNAR1 | PTPRC | 25361965 | interaction type | N/A | PTMCode2 |
| PTPRC | IFNAR1 | 25361965 | interaction type | N/A | PTMCode2 |
| IFNAR1 | IFNW1 | 25361965 | interaction type | N/A | PTMCode2 |
| IFNW1 | IFNAR1 | 25361965 | interaction type | N/A | PTMCode2 |
| IFNAR1 | IFNB1 | 25361965 | interaction type | N/A | PTMCode2 |
| IFNB1 | IFNAR1 | 25361965 | interaction type | N/A | PTMCode2 |
| IFNAR1 | PTPN6 | 25361965 | interaction type | N/A | PTMCode2 |
| PTPN6 | IFNAR1 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HNRNPK | IFNAR1 | 25348397 | N/A | physical interaction | ComPPI |
| STAT1 | IFNAR1 | 24234451 25348397 9121453 | association,physical association | pull down | ComPPI,IntAct |
| TYK2 | IFNAR1 | 10523853 14525934 24234451 25348397 95059042 9677371 9733772 | physical association | experimental interaction detection,molecular sieving,pull down,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| PTPN6 | IFNAR1 | 14525934 25348397 8524272 9029147 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| RACK1 | IFNAR1 | 11301323 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| MAPK1 | IFNAR1 | 14525934 25348397 9029147 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| SOCS1 | IFNAR1 | 25348397 | N/A | physical interaction | ComPPI |
| ABRAXAS2 | IFNAR1 | 25348397 | N/A | physical interaction | ComPPI |
| PIK3R1 | IFNAR1 | 10542297 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| PTPN11 | IFNAR1 | 14525934 25348397 9029147 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| CRKL | IFNAR1 | 11167825 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| LCK | IFNAR1 | 14525934 25348397 9403695 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| EP300 | IFNAR1 | 17923090 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| USP7 | IFNAR1 | 25348397 | N/A | physical interaction | ComPPI |
| ZAP70 | IFNAR1 | 14525934 25348397 9403695 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| PRKACA | IFNAR1 | 14525934 25348397 9029147 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| YWHAB | IFNAR1 | 25348397 | N/A | physical interaction | ComPPI |
| IFNW1 | IFNAR1 | 14525934 1834641 21854986 24234451 25348397 | N/A | experimental interaction detection,x-ray crystallography,in vivo | ComPPI,HPRD,IntAct |
| IFNAR1 | IFNA2 | 14525934 1834641 25348397 | N/A | experimental interaction detection,physical interaction,biochemical,genetic,in vivo | ComPPI,HPRD |
| IFNAR1 | IFNB1 | 14525934 1834641 25348397 | N/A | coimmunoprecipitation,experimental interaction detection,physical interaction,biochemical,in vivo | ComPPI,HPRD |
| IFNAR1 | STAT2 | 11786546 12220192 14525934 24234451 25348397 7559568 8605876 9121453 9677371 | association | anti bait coimmunoprecipitation,experimental interaction detection,pull down,surface plasmon resonance,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| IFNAR1 | PRMT1 | 14525934 25348397 9029147 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| IFNAR1 | STAT3 | 14525934 25348397 8626489 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| IFNAR1 | IFNA1 | 14525934 25348397 7932753 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| IFNAR1 | PTPRC | 25348397 | N/A | in vitro,in vivo | ComPPI |
| IFNAR1 | FBXW11 | 14525934 14532120 24234451 25348397 | physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| IFNAR1 | AP2M1 | 25348397 | N/A | physical interaction | ComPPI |
| IFNAR1 | BTRC | 25348397 | N/A | physical interaction | ComPPI |
| IFNAR1 | PRKD2 | 25348397 | N/A | physical interaction | ComPPI |
| IFNAR1 | STAT6 | 25348397 | N/A | physical interaction | ComPPI |
| IFNAR1 | IFNAR2 | 14525934 15389589 21854986 24234451 25348397 | physical association | coimmunoprecipitation,experimental interaction detection,x-ray crystallography,physical interaction | ComPPI,HPRD,IntAct |
| IFNAR1 | TNFRSF10A | 25348397 | N/A | physical interaction | ComPPI |
| IFNAR1 | TRIM25 | 25348397 | N/A | physical interaction | ComPPI |
| IFNAR1 | SHMT2 | 25348397 | N/A | physical interaction | ComPPI |
| IFNAR1 | HSPD1 | 25348397 | N/A | physical interaction | ComPPI |
| IFNAR1 | SHMT1 | 25348397 | N/A | physical interaction | ComPPI |
| IFNAR1 | UBA1 | 25348397 | N/A | physical interaction | ComPPI |
| IFNAR1 | HNRNPU | 25348397 | N/A | physical interaction | ComPPI |
| IFNAR1 | YWHAE | 25348397 | N/A | physical interaction | ComPPI |
| IFNAR1 | BRCC3 | 25348397 | N/A | physical interaction | ComPPI |
| IFNAR1 | JAK1 | 25348397 | N/A | two hybrid,physical interaction,biochemical,genetic | ComPPI |
| IFNAR1 | IFNA8 | 25348397 | N/A | physical interaction,biochemical | ComPPI |
| PKM | IFNAR1 | 25348397 | N/A | physical interaction | ComPPI |
| CSNK1A1 | IFNAR1 | 15337770 16551269 19805514 19948722 21666722 21695243 21865166 27898060 | inhibition | N/A | OmniPath |
| IFNAR1 | IFNGR1 | 18929502 27898060 | stimulant | N/A | OmniPath |
| IFNAR1 | STAT6 | 10490982 27898060 | N/A | N/A | OmniPath |
| IFNAR1 | TRAF2 | 18362156 27898060 | N/A | N/A | OmniPath |
| IFNAR1 | PTPN6 | 27898060 8524272 9029147 | N/A | N/A | OmniPath |
| IFNAR1 | STAT1 | 10582086 27898060 9121453 | stimulant | N/A | OmniPath |
| IFNAR1 | PRMT1 | 27898060 9029147 | N/A | N/A | OmniPath |
| IFNAR1 | JAK1 | 15120645 27898060 8524272 9334213 | stimulant | N/A | OmniPath |
| JAK1 | IFNAR1 | 15120645 27898060 8524272 9334213 | N/A | N/A | OmniPath |
| IFNAR1 | TYK2 | 10523853 14647450 15120645 15337770 15356134 18474601 24704786 27898060 7526154 7559568 8524272 8605876 8628273 8702790 9461596 95059042 9677371 9733772 | stimulant | N/A | OmniPath |
| TYK2 | IFNAR1 | 10523853 11786546 12220192 14647450 15120645 15337770 15356134 18474601 23129613 24704786 27898060 7526154 7559568 8524272 8605876 8628273 8700538 8702790 9121453 9461596 95059042 9677371 9733772 | stimulant | N/A | OmniPath |
| MAPK14 | IFNAR1 | 21695243 27898060 | N/A | N/A | OmniPath |
| IFNAR1 | STAT2 | 11786546 12220192 15356134 27898060 7559568 8605876 9121453 9677371 | N/A | N/A | OmniPath |
| STAT2 | IFNAR1 | 11786546 12220192 15356134 27898060 7559568 8605876 9121453 9677371 | N/A | N/A | OmniPath |
| IFNB1 | IFNAR1 | 10049744 11278538 1834641 27898060 7592797 7623815 8181059 | stimulant | N/A | OmniPath |
| IFNAR1 | STAT3 | 27898060 8626489 | N/A | N/A | OmniPath |
| STAT3 | IFNAR1 | 27898060 8626489 | N/A | N/A | OmniPath |
| IFNA1 | IFNAR1 | 11698684 21856167 27898060 7932753 8181059 | stimulant | N/A | OmniPath |
| IFNAR1 | AP2M1 | 18056411 18474601 27898060 | N/A | N/A | OmniPath |
| IFNAR1 | FBXW11 | 14532120 15337770 18056411 27898060 | N/A | N/A | OmniPath |
| FBXW11 | IFNAR1 | 14532120 15337770 18056411 27898060 | N/A | N/A | OmniPath |
| IFNAR1 | IFNAR2 | 11698684 15389589 21854986 27898060 8969169 | N/A | N/A | OmniPath |
| IFNAR2 | IFNAR1 | 11698684 15389589 21854986 27898060 8969169 | N/A | N/A | OmniPath |
| IFNA17 | IFNAR1 | 21856167 27898060 7623815 | N/A | N/A | OmniPath |
| IFNW1 | IFNAR1 | 11278538 1834641 27898060 | stimulant | N/A | OmniPath |
| IFNA16 | IFNAR1 | 21856167 27898060 | N/A | N/A | OmniPath |
| IFNA6 | IFNAR1 | 21856167 27898060 | N/A | N/A | OmniPath |
| IFNA7 | IFNAR1 | 21856167 27898060 | N/A | N/A | OmniPath |
| IFNA10 | IFNAR1 | 21856167 27898060 | N/A | N/A | OmniPath |
| IFNA4 | IFNAR1 | 21856167 27898060 | N/A | N/A | OmniPath |
| IFNA8 | IFNAR1 | 21856167 27898060 7592797 | N/A | N/A | OmniPath |
| IFNA14 | IFNAR1 | 21856167 27898060 | N/A | N/A | OmniPath |
| IFNA21 | IFNAR1 | 21856167 27898060 | N/A | N/A | OmniPath |
| IFNA5 | IFNAR1 | 21856167 27898060 | N/A | N/A | OmniPath |