Gene Information gene info

  1. Home

GENE：JAK1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol JAK1
FullNmae Janus kinase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6190
EnsembleID ENSG00000162434
Uniprot P23458

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
JAK1 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
JAK1 necroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
JAK1 GO:0004713,GO:0004713,GO:0004713,GO:0004715,GO:0004715,GO:0004715,GO:0005131,GO:0005131,GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0005737,GO:0005768,GO:0005829,GO:0005829,GO:0005856,GO:0005886,GO:0005925,GO:0006468,GO:0007259,GO:0007259,GO:0007259,GO:0007259,GO:0007260,GO:0009898,GO:0019221,GO:0019221,GO:0019903,GO:0030154,GO:0031234,GO:0031234,GO:0031625,GO:0031730,GO:0034112,GO:0035556,GO:0035723,GO:0035771,GO:0038110,GO:0038110,GO:0038113,GO:0038154,GO:0038196,GO:0046677,GO:0046872,GO:0060333,GO:0060333,GO:0060333,GO:0060337,GO:0060337,GO:0060337,GO:0060397,GO:0070102,GO:0070102,GO:0072540,GO:0098586,GO:0150105,GO:1900182,GO:1903672

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
JAK1 hsa:3716 path:hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human)
JAK1 hsa:3716 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
JAK1 hsa:3716 path:hsa04217 Necroptosis - Homo sapiens (human)
JAK1 hsa:3716 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)
JAK1 hsa:3716 path:hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)
JAK1 hsa:3716 path:hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human)
JAK1 hsa:3716 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
JAK1 hsa:3716 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)
JAK1 hsa:3716 path:hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human)
JAK1 hsa:3716 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05140 Leishmaniasis - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05145 Toxoplasmosis - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05152 Tuberculosis - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05160 Hepatitis C - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05161 Hepatitis B - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05162 Measles - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05164 Influenza A - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05200 Pathways in cancer - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05212 Pancreatic cancer - Homo sapiens (human)
JAK1 hsa:3716 path:hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
JAK1 PLAU 11306493 18633355 19833085 21840487 22470492 22595692 26192618 27216177 7512720 7521688 interaction type N/A ACSN
JAK1 PLAUR 11306493 18633355 19833085 21840487 22470492 22595692 26192618 27216177 7512720 7521688 interaction type N/A ACSN
JAK1 LIF 11306493 19833085 21840487 22595692 24857661 26192618 7512720 7521688 interaction type N/A ACSN
JAK1 LIFR 11306493 19833085 21840487 22595692 24857661 26192618 7512720 7521688 interaction type N/A ACSN
JAK1 IFNGR1 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26192618 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217 interaction type N/A ACSN
JAK1 IFNGR2 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12438563 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16467876 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24243840 24658051 26192618 26755705 27216177 29145629 2965306 6425450 7512720 7521688 9834059 9864217 interaction type,physical association inferred by curator ACSN,Reactome
JAK1 IFNG 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26192618 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217 interaction type N/A ACSN
JAK1 JAK2 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26192618 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217 interaction type N/A ACSN
JAK1 IL6R 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 22595692 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26192618 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545 interaction type N/A ACSN
JAK1 TYK2 10022928 10415122 10433356 10485906 10542212 10542297 10623821 10982844 11160275 11207245 11306493 11371360 11694501 11698286 11867689 11870632 11875494 11964292 12087100 12223527 12401408 12469119 12496409 12734330 12754507 12811837 12818165 1439146 14607900 14610620 14657224 14764663 14764690 14764699 15099563 15120653 15166220 15282297 15312780 15356132 15449939 15573129 15579430 15864272 16171819 16200688 16243976 16413922 16424049 16713974 16982608 16987978 17351669 17404308 17485448 17513775 17969444 18209571 18250477 1825141 18389480 18451175 18508557 18555777 18555778 18830264 19457860 19581928 19833085 20138012 20184663 20406969 20462497 20510870 20671117 20856220 21097505 21115385 21191065 21220452 21469115 21716315 21840487 21930765 21930769 22383755 22595692 23034983 23124025 23291588 23390297 23567181 23704922 24011634 24030977 24091328 24243840 24346288 24418198 25002027 25582338 26192618 26201938 26268945 26755705 27216177 27557510 29145629 2965306 7512720 7521688 7526154 7543512 7590867 8197134 8232552 8605876 8621447 8702790 8837607 8910398 8943354 9312047 9334213 9535722 9822675 9834059 9845545 interaction type,physical association inferred by curator ACSN,Reactome
JAK1 IL15 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 26192618 7512720 7521688 7523571 7543512 interaction type N/A ACSN
JAK1 IL15RA 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 26192618 7512720 7521688 7523571 7543512 interaction type N/A ACSN
JAK1 IL2RB 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26192618 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766 interaction type N/A ACSN
JAK1 IL2RG 10358772 10426994 10485906 10807786 10820393 10849428 10856136 11160275 11371360 11867689 11870632 11907067 12095053 12223527 12244150 12401408 12496409 12811837 12818165 14607946 14610620 15289500 15536084 15563472 16081783 16212621 16243976 16413922 16713974 16785506 16799562 16815076 17371980 17398124 17404308 17459805 17485448 18250477 1825141 18758473 19528259 19833085 19913445 20007590 20184663 20406969 20510870 20856220 21307131 21469115 21840487 22224781 23124025 23390297 23650441 24030977 24091328 24751819 24829413 25582338 26192618 26755705 27216177 2965306 6164929 7512720 7521688 7523571 8683106 9625766 9834059 interaction type N/A ACSN
JAK1 IFNAR1 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 26192618 7512720 7521688 7543512 interaction type N/A ACSN
JAK1 IFNAR2 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 26192618 7512720 7521688 7543512 interaction type N/A ACSN
JAK1 IL21 10426994 11907067 12244150 12811837 15536084 16081783 16713974 16785506 19833085 20856220 21840487 23124025 24751819 26192618 7512720 7521688 interaction type N/A ACSN
JAK1 IL2 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26192618 26755705 2965306 6164929 7512720 7521688 8683106 9625766 interaction type N/A ACSN
JAK1 IL4 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26192618 27216177 2965306 7512720 7521688 7543512 9834059 interaction type N/A ACSN
JAK1 IL4R 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 14657224 15099563 16243976 16413922 17404308 17485448 18250477 1825141 18451175 19833085 20184663 20406969 20510870 20856220 21097505 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26192618 26755705 27216177 2965306 7512720 7521688 7543512 9535722 9834059 interaction type N/A ACSN
JAK1 IL13 10485906 11867689 12223527 12401408 14610620 14657224 15099563 16243976 16413922 17404308 17485448 18250477 18451175 19833085 20184663 20406969 20510870 20856220 21097505 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26192618 26755705 27216177 7512720 7521688 7543512 9535722 interaction type N/A ACSN
JAK1 IL13RA1 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 14657224 15099563 16243976 16413922 17404308 17485448 18250477 1825141 18451175 19833085 20184663 20406969 20510870 20856220 21097505 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26192618 26755705 27216177 2965306 7512720 7521688 7543512 9535722 9834059 interaction type N/A ACSN
JAK1 IL10 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26192618 26755705 7512720 7521688 7543512 9834059 interaction type N/A ACSN
JAK1 IL10RA 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26192618 26755705 7512720 7521688 7543512 9834059 interaction type N/A ACSN
JAK1 IL10RB 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26192618 26755705 7512720 7521688 7543512 9834059 interaction type N/A ACSN
JAK1 IL6 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26192618 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545 interaction type N/A ACSN
JAK1 CSF3R 11867689 14610620 18400509 19833085 20237318 20406969 20581311 21840487 22754783 24091328 26192618 27216177 7512720 7521688 interaction type N/A ACSN
JAK1 ITGB5 11306493 18633355 19833085 21840487 22470492 22595692 26192618 27216177 7512720 7521688 interaction type N/A ACSN
JAK1 STAT3 10426994 10851062 10918587 11163236 11294897 11306517 11350938 11418623 11564763 11706020 11722592 11907067 11940572 12040185 12093291 12244095 12244150 12351624 12517932 12576423 12626508 12626585 12759422 12811837 14551213 14565860 14764663 15261459 15536084 15805299 16081783 16713974 16785506 17878297 18389480 18669613 18941194 19535621 19833085 20169197 20856220 20966397 21098725 21420464 21840487 23124025 23331499 24751819 25297818 26192618 27774606 29145629 7512720 7521688 7796300 8085155 8272872 8626374 8662591 8662795 8662928 8756628 9535918 9566874 9651359 interaction type,phosphorylation reaction,stimulation,physical association inferred by curator ACSN,Reactome,SignaLink,SignaLink
OSM JAK1 16204061 21840487 26192618 interaction type N/A ACSN
FAP JAK1 21051638 23402812 24778314 25593080 26192618 27216177 7911242 interaction type N/A ACSN
JAK1 STAT1 10022928 10426994 10851062 10918587 10982844 11294897 11306517 11418623 11722592 11839738 11907067 11972023 12040185 12093291 12244150 12517932 12637327 12759422 12811837 12817007 14565860 14764663 15261459 15322115 15536084 16081783 16713974 16785506 18389480 18508557 18941194 18988627 19535621 19833085 20169197 20856220 21840487 22306691 23124025 23331499 24058793 24243840 24751819 25297818 26192618 27774606 29145629 7510216 7512720 7521688 7543024 7657660 7690989 7796299 8156998 8232552 8631301 8662591 8662795 8756628 9535918 interaction type,enzymatic reaction,stimulation,physical association inferred by curator ACSN,Reactome,SignaLink,SignaLink
JAK1 STAT6 10485906 10856136 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 22661199 23124025 23331499 23390297 24030977 24091328 26192618 27216177 2965306 7512720 7521688 9045682 9834059 interaction type,phosphorylation reaction,stimulation N/A ACSN,SignaLink,SignaLink
JAK1 IRS2 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 26192618 27216177 29145629 2965306 7512720 7521688 9233603 9834059 interaction type,physical association inferred by curator ACSN,Reactome
JAK1 IL18 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 26192618 27216177 2965306 7512720 7521688 9834059 interaction type N/A ACSN
JAK1 MICA 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 26192618 7512720 7521688 7523571 interaction type N/A ACSN
JAK1 MICB 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 26192618 7512720 7521688 7523571 interaction type N/A ACSN
JAK1 STAT4 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 26192618 7512720 7521688 7523571 interaction type N/A ACSN
JAK1 TNF 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26192618 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545 interaction type N/A ACSN
SOCS1 JAK1 10201892 10485906 11133764 12193701 12223527 12811837 18988627 21469115 23124025 23331499 26192618 interaction type,stimulation N/A ACSN,SignaLink,SignaLink
PLCG2 JAK1 14978237 23180781 physical association anti tag coimmunoprecipitation InnateDB
STAT1 JAK1 14978237 15284024 15978943 23180781 physical association anti tag coimmunoprecipitation InnateDB
JAK1 PLA2G4A 23180781 8612580 physical association anti tag coimmunoprecipitation InnateDB
PTPN11 JAK1 12270932 23180781 8790359 physical association anti tag coimmunoprecipitation InnateDB
EGFR JAK1 15284024 23180781 physical association anti tag coimmunoprecipitation InnateDB
STAT3 JAK1 15284024 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL2RB JAK1 10373548 12133952 23180781 7973657 8041779 physical association anti tag coimmunoprecipitation,pull down InnateDB
PTPN6 JAK1 23180781 23331499 8524272 9852037 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink,SignaLink
IFNAR1 JAK1 10022928 10542297 10982844 11694501 15120645 15312780 15449939 16171819 16987978 17351669 17969444 18508557 23180781 23331499 24243840 29145629 7526154 8197134 8232552 8524272 8605876 8621447 8702790 8943354 9334213 stimulation,physical association gst pull down,inferred by curator InnateDB,Reactome,SignaLink,SignaLink
JAK3 JAK1 12207328 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRS1 JAK1 23180781 23331499 9233603 9492017 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink
IRS2 JAK1 23180781 9233603 physical association anti tag coimmunoprecipitation InnateDB
TNFRSF1A JAK1 15173123 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAP3K5 JAK1 19287004 23180781 phosphorylation reaction protein kinase assay InnateDB
JAK1 JAK1 11823427 11943154 12438563 12829785 14764690 15173123 16051226 16467876 16868551 19723038 19920145 22306691 23180781 24243840 24710148 24771852 26467481 27119567 29145629 7812050 8120391 8134389 8140422 8272873 8390097 8790359 9020188 9238703 9382798 phosphorylation reaction,bind,physical association,up-regulates activity inferred by curator,in-gel kinase assay InnateDB,Reactome,Signor
SOCS3 JAK1 10373548 16459330 23180781 23331499 stimulation,physical association anti tag coimmunoprecipitation,gst pull down InnateDB,SignaLink,SignaLink
IL9R JAK1 23180781 23331499 8756628 9535918 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink
IFNAR2 JAK1 12133952 18988627 23180781 23331499 7988557 stimulation,physical association pull down InnateDB,SignaLink,SignaLink
IL4R JAK1 12133952 12223527 23180781 23331499 7929391 stimulation,physical association anti tag coimmunoprecipitation,pull down InnateDB,SignaLink
IL10RA JAK1 12133952 12974481 23180781 23331499 stimulation,physical association pull down InnateDB,SignaLink,SignaLink
IFNGR1 JAK1 12040185 12133952 12438563 16467876 23180781 23331499 24243840 29145629 stimulation,physical association pull down,inferred by curator InnateDB,Reactome,SignaLink,SignaLink
IL21R JAK1 11016959 11418623 23180781 23331499 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink
IL7R JAK1 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
TIRAP JAK1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 JAK1 23180781 23236554 physical association anti tag coimmunoprecipitation InnateDB
JAK1 STAT2 10022928 10542297 10982844 12040185 16987978 18508557 18988627 23331499 24243840 29145629 8197134 8232552 8605876 9020188 stimulation,physical association inferred by curator Reactome,SignaLink,SignaLink
IFNG JAK1 10986460 12438563 12915721 1396683 15143187 15530433 16237089 16467876 18591661 20304997 29145629 7510216 7514165 7615558 7617032 7673114 8550631 8631301 9111318 physical association inferred by curator Reactome
JAK1 SYK 10825200 29145629 7600304 physical association inferred by curator Reactome
IL7 JAK1 2317865 24243840 29145629 physical association inferred by curator Reactome
JAK1 IRS1 11162588 23331499 29145629 7499365 9013940 9233603 interaction type,physical association inferred by curator Reactome,SignaLink
JAK1 STAT5B 19864382 29145629 7489741 7719938 8709637 8756628 9535918 9715265 physical association inferred by curator Reactome
JAK1 STAT5A 19864382 29145629 7489741 7719938 8709637 8756628 9535918 9715265 physical association inferred by curator Reactome
JAK1 PTPN6 18508557 24243840 29145629 8943354 dephosphorylation reaction inferred by curator Reactome
PTPN1 JAK1 11694501 24243840 29145629 dephosphorylation reaction inferred by curator Reactome
JAK1 PRKCD 11972023 15322115 29145629 enzymatic reaction inferred by curator Reactome
JAK1 PTPN11 12403768 21071413 23331499 8995399 stimulation N/A SignaLink,SignaLink
IFNB1 JAK1 10918594 23331499 stimulation N/A SignaLink,SignaLink
PTPN2 JAK1 11909529 23331499 stimulation N/A SignaLink,SignaLink
IL20RA JAK1 12941475 23331499 stimulation N/A SignaLink,SignaLink
IL22RA1 JAK1 12941475 23331499 stimulation N/A SignaLink,SignaLink
IFNGR2 JAK1 15120645 23331499 stimulation N/A SignaLink,SignaLink
CSF3R JAK1 23331499 7512720 stimulation N/A SignaLink
IL2RG JAK1 23331499 7721895 7973658 stimulation N/A SignaLink
JAK1 SHC1 23331499 9670964 stimulation N/A SignaLink
JAK1 DBP 23331499 9852261 stimulation N/A SignaLink
GHR JAK1 10502458 23331499 stimulation N/A SignaLink
JAK1 JAK3 10825200 23331499 stimulation N/A SignaLink
LIFR JAK1 11294841 23331499 stimulation N/A SignaLink
CNTFR JAK1 11464862 23331499 stimulation N/A SignaLink
PTPRC JAK1 11201744 11994288 23331499 stimulation N/A SignaLink
IL6ST JAK1 11468294 11742534 12487370 23331499 stimulation N/A SignaLink
IL20RB JAK1 12941475 23331499 stimulation N/A SignaLink
IL10RB JAK1 12974481 23331499 stimulation N/A SignaLink
IFNLR1 JAK1 15120645 23331499 stimulation N/A SignaLink
OSMR JAK1 10586060 15935618 23331499 stimulation N/A SignaLink
LEPR JAK1 16173077 23331499 stimulation N/A SignaLink
IL31RA JAK1 18926762 23331499 stimulation N/A SignaLink
JAK1 F1QZU5 12403768 21559328 8995399 inhibition N/A SignaFish
Q803M6 JAK1 20424185 21559328 9096349 inhibition N/A SignaFish

Source Target Pmid Interactiontype Methods Database
ARRB1 JAK1 20005715 interaction type N/A PSP,SignaLink
GRB2 JAK1 11527382 20005715 21071413 interaction type N/A PSP,SignaLink
IRS1 JAK1 20005715 interaction type N/A PSP,SignaLink
IRS2 JAK1 18988627 20005715 7499365 interaction type N/A PSP,SignaLink
PIK3R1 JAK1 20005715 interaction type N/A PSP
SH2B2 JAK1 20005715 interaction type N/A PSP,SignaLink
SHB JAK1 12200137 18988627 20005715 interaction type N/A PSP,SignaLink
SOCS1 JAK1 20005715 interaction type N/A PSP
SOCS3 JAK1 20005715 interaction type N/A PSP
STAM JAK1 18988627 20005715 9133424 interaction type N/A PSP,SignaLink
SOCS1 JAK1 20005715 20005715 N/A N/A SignaLink
SOCS3 JAK1 20005715 20005715 N/A N/A SignaLink
PIK3R1 JAK1 18988627 20005715 20005715 9774657 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR JAK1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 JAK1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C JAK1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 JAK1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 JAK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA JAK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF JAK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 JAK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 JAK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 JAK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS JAK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 JAK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A JAK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF JAK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 JAK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 JAK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 JAK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 JAK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
BRCA1 JAK1 11163768 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002075FA JAK1 20299512 rna interference,inhibition western blot,miRNA interference luciferase reporter assay miRSponge
URS00002075FA JAK1 20299512 22473208 25416803 mrna cleavage,inhibition western blot,clip,miRNA interference luciferase reporter assay TarBase
URS00000600E6 JAK1 17242205 22473208 25307786 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000042E1F JAK1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED JAK1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000041CB9C JAK1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000008F0CF JAK1 24429361 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,chromatin immunoprecipitation assay,rna immunoprecipitation,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001DE669 JAK1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F JAK1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 JAK1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 JAK1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 JAK1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 JAK1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 JAK1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 JAK1 25416803 25589644 mrna cleavage,inhibition western blot,rna immunoprecipitation,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
JAK1 H3C1 22135298 phosphorylation N/A PhosphoSite
JAK1 MAP3K5 22135298 phosphorylation N/A PhosphoSite
JAK1 STAT1 22135298 phosphorylation N/A PhosphoSite
JAK3 JAK1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
OSMR JAK1 25361965 interaction type N/A PTMCode2
JAK1 OSMR 25361965 interaction type N/A PTMCode2
STAT3 JAK1 25361965 interaction type N/A PTMCode2
JAK1 STAT3 25361965 interaction type N/A PTMCode2
IL21R JAK1 25361965 interaction type N/A PTMCode2
JAK1 IL21R 25361965 interaction type N/A PTMCode2
FES JAK1 25361965 interaction type N/A PTMCode2
JAK1 FES 25361965 interaction type N/A PTMCode2
IL7R JAK1 25361965 interaction type N/A PTMCode2
JAK1 IL7R 25361965 interaction type N/A PTMCode2
TYK2 JAK1 25361965 interaction type N/A PTMCode2
JAK1 TYK2 25361965 interaction type N/A PTMCode2
IL2RG JAK1 25361965 interaction type N/A PTMCode2
JAK1 IL2RG 25361965 interaction type N/A PTMCode2
RAF1 JAK1 25361965 interaction type N/A PTMCode2
JAK1 RAF1 25361965 interaction type N/A PTMCode2
PTK2B JAK1 25361965 interaction type N/A PTMCode2
JAK1 PTK2B 25361965 interaction type N/A PTMCode2
IL4R JAK1 25361965 interaction type N/A PTMCode2
JAK1 IL4R 25361965 interaction type N/A PTMCode2
GHR JAK1 25361965 interaction type N/A PTMCode2
JAK1 GHR 25361965 interaction type N/A PTMCode2
IL6ST JAK1 25361965 interaction type N/A PTMCode2
JAK1 IL6ST 25361965 interaction type N/A PTMCode2
IL10RA JAK1 25361965 interaction type N/A PTMCode2
JAK1 IL10RA 25361965 interaction type N/A PTMCode2
CSF3R JAK1 25361965 interaction type N/A PTMCode2
JAK1 CSF3R 25361965 interaction type N/A PTMCode2
STAM2 JAK1 25361965 interaction type N/A PTMCode2
JAK1 STAM2 25361965 interaction type N/A PTMCode2
FER JAK1 25361965 interaction type N/A PTMCode2
JAK1 FER 25361965 interaction type N/A PTMCode2
IFNAR1 JAK1 25361965 interaction type N/A PTMCode2
JAK1 IFNAR1 25361965 interaction type N/A PTMCode2
STAT5A JAK1 25361965 interaction type N/A PTMCode2
JAK1 STAT5A 25361965 interaction type N/A PTMCode2
EIF2AK2 JAK1 25361965 interaction type N/A PTMCode2
JAK1 EIF2AK2 25361965 interaction type N/A PTMCode2
JAK1 BRCA1 25361965 interaction type N/A PTMCode2
BRCA1 JAK1 25361965 interaction type N/A PTMCode2
JAK1 PTPRC 25361965 interaction type N/A PTMCode2
PTPRC JAK1 25361965 interaction type N/A PTMCode2
JAK1 IFNGR1 25361965 interaction type N/A PTMCode2
IFNGR1 JAK1 25361965 interaction type N/A PTMCode2
JAK1 IL6R 25361965 interaction type N/A PTMCode2
IL6R JAK1 25361965 interaction type N/A PTMCode2
JAK1 ABL1 25361965 interaction type N/A PTMCode2
ABL1 JAK1 25361965 interaction type N/A PTMCode2
JAK1 SYK 25361965 interaction type N/A PTMCode2
SYK JAK1 25361965 interaction type N/A PTMCode2
JAK1 IRS2 25361965 interaction type N/A PTMCode2
IRS2 JAK1 25361965 interaction type N/A PTMCode2
JAK1 STAM 25361965 interaction type N/A PTMCode2
STAM JAK1 25361965 interaction type N/A PTMCode2
JAK1 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ JAK1 25361965 interaction type N/A PTMCode2
JAK1 CSF2RB 25361965 interaction type N/A PTMCode2
CSF2RB JAK1 25361965 interaction type N/A PTMCode2
JAK1 JAKMIP1 25361965 interaction type N/A PTMCode2
JAKMIP1 JAK1 25361965 interaction type N/A PTMCode2
JAK1 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 JAK1 25361965 interaction type N/A PTMCode2
JAK1 JAK3 25361965 interaction type N/A PTMCode2
STAT6 JAK1 25361965 interaction type N/A PTMCode2
JAK1 STAT6 25361965 interaction type N/A PTMCode2
IL27RA JAK1 25361965 interaction type N/A PTMCode2
JAK1 IL27RA 25361965 interaction type N/A PTMCode2
IL9R JAK1 25361965 interaction type N/A PTMCode2
JAK1 IL9R 25361965 interaction type N/A PTMCode2
IRS1 JAK1 25361965 interaction type N/A PTMCode2
JAK1 IRS1 25361965 interaction type N/A PTMCode2
GRB2 JAK1 25361965 interaction type N/A PTMCode2
JAK1 GRB2 25361965 interaction type N/A PTMCode2
IL3RA JAK1 25361965 interaction type N/A PTMCode2
JAK1 IL3RA 25361965 interaction type N/A PTMCode2
ERBB2 JAK1 25361965 interaction type N/A PTMCode2
JAK1 ERBB2 25361965 interaction type N/A PTMCode2
PDGFRA JAK1 25361965 interaction type N/A PTMCode2
JAK1 PDGFRA 25361965 interaction type N/A PTMCode2
PIK3R1 JAK1 25361965 interaction type N/A PTMCode2
JAK1 PIK3R1 25361965 interaction type N/A PTMCode2
TSHR JAK1 25361965 interaction type N/A PTMCode2
JAK1 TSHR 25361965 interaction type N/A PTMCode2
PTPN2 JAK1 25361965 interaction type N/A PTMCode2
JAK1 PTPN2 25361965 interaction type N/A PTMCode2
SOCS3 JAK1 25361965 interaction type N/A PTMCode2
JAK1 SOCS3 25361965 interaction type N/A PTMCode2
TNFRSF1A JAK1 25361965 interaction type N/A PTMCode2
JAK1 TNFRSF1A 25361965 interaction type N/A PTMCode2
IL2RB JAK1 25361965 interaction type N/A PTMCode2
JAK1 IL2RB 25361965 interaction type N/A PTMCode2
JAK1 JAK1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SOCS3 JAK1 10707961 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
NPM1 JAK1 25348397 N/A physical interaction ComPPI
STAT1 JAK1 10918587 10982844 11294897 11722592 11839738 12637327 12817007 14525934 15322115 25348397 7543024 7657660 7690989 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
UBL4A JAK1 25348397 N/A physical interaction ComPPI
TYK2 JAK1 14525934 25348397 7589562 8702790 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN6 JAK1 14525934 25348397 7629131 9520455 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HSP90AB1 JAK1 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
RACK1 JAK1 12960323 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ERBB2 JAK1 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
BTK JAK1 14525934 25348397 9178903 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SYK JAK1 10825200 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SHB JAK1 12200137 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TEC JAK1 14525934 25348397 9178903 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
IL6ST JAK1 11468294 11742534 14525934 25348397 N/A coimmunoprecipitation,transmission electron microscopy,experimental interaction detection,molecular sieving,physical interaction,ion exchange chromatography,in vitro,in vivo ComPPI,HPRD
PTK2B JAK1 10702271 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TGFBR2 JAK1 25348397 N/A physical interaction ComPPI
SOCS1 JAK1 11133764 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PIK3R1 JAK1 14525934 25348397 9774657 N/A experimental interaction detection,in vivo ComPPI,HPRD
PTPN11 JAK1 11036942 12403768 14525934 25348397 8995399 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PRKCA JAK1 17290288 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SH2B2 JAK1 11751854 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
INPP5D JAK1 10875931 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PLCG2 JAK1 25348397 N/A in vivo ComPPI
OSMR JAK1 10586060 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
GRB2 JAK1 11527382 14525934 25348397 8536716 N/A experimental interaction detection,physical interaction,genetic,in vivo ComPPI,HPRD
PDGFRB JAK1 14525934 25348397 8657151 9484840 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
FES JAK1 11160325 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
IRS2 JAK1 14525934 25348397 7499365 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
GHR JAK1 10502458 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
IFNAR1 JAK1 25348397 N/A two hybrid,physical interaction,biochemical,genetic ComPPI
HSP90AA1 JAK1 25348397 N/A physical interaction ComPPI
PDGFRA JAK1 11468294 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
NTRK1 JAK1 25348397 N/A physical interaction ComPPI
STAT2 JAK1 14525934 25348397 9020188 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
IFNGR1 JAK1 12133952 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK1 BRCA1 11163768 14525934 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
JAK1 STAT3 10918587 11294897 11350938 11722592 11940572 12244095 12576423 12626508 14525934 14551213 24234451 25065853 25348397 8272872 8626374 9566874 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
JAK1 STAM 14525934 25348397 9133424 N/A experimental interaction detection,in vivo ComPPI,HPRD
JAK1 CXCR4 12163560 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
JAK1 CCR1 14525934 14674010 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
JAK1 CCR5 10037796 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
JAK1 IL7R 14525934 15996891 25348397 8647212 N/A experimental interaction detection,in vivo ComPPI,HPRD
JAK1 IL2RG 14525934 25348397 7973658 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK1 INSR 12456798 14525934 25348397 9492017 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JAK1 PRKCZ 14525934 15526032 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
JAK1 IL3RA 14525934 15988755 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
JAK1 STAT6 10856136 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
JAK1 PLA2G4A 14525934 25348397 8612580 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK1 JAKMIP1 14525934 15277531 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
JAK1 EIF2AK2 14525934 17290288 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK1 CSF3R 14525934 25348397 7512720 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JAK1 CSF2RB 11557047 14525934 24234451 25348397 9516124 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
JAK1 IL2RB 12133952 14525934 25348397 7973659 8700888 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK1 IL10RA 10433356 12133952 12374810 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JAK1 IRS1 11162588 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JAK1 IL4R 12133952 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JAK1 PTPRC 25348397 N/A in vitro ComPPI
JAK1 MDK 14525934 25348397 9452495 N/A experimental interaction detection,in vitro ComPPI,HPRD
JAK1 RAF1 14525934 25348397 9446616 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK1 PLAUR 14525934 25348397 9417082 N/A coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JAK1 FER 12738762 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
JAK1 TNFRSF1A 11801527 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JAK1 IL9R 14525934 25348397 8756628 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JAK1 JAK3 12559972 14525934 25348397 9553136 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JAK1 STAT5A 11722592 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK1 TSHR 10809230 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JAK1 PRMT5 10531356 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
JAK1 IL21R 11016959 11418623 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK1 STAM2 10899310 10993906 14525934 24234451 25348397 phosphorylation reaction anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
JAK1 PTPN2 25348397 N/A in vitro,in vivo ComPPI
JAK1 ELP2 10954736 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK1 ATIC 25348397 N/A physical interaction ComPPI
JAK1 ARRB1 25348397 N/A physical interaction ComPPI
JAK1 ELF3 25348397 N/A physical interaction ComPPI
JAK1 ABL1 12130510 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
JAK1 ABL2 25348397 N/A physical interaction ComPPI
JAK1 IL27RA 25348397 N/A physical interaction ComPPI
JAK1 STAT5B 25348397 N/A physical interaction ComPPI
JAK1 IL5RA 14525934 24234451 25348397 9516124 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
JAK1 IFNAR2 12133952 14525934 16710296 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction ComPPI,HPRD,IntAct
JAK1 AGO4 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK1 TIRAP 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK1 H3-4 25348397 N/A physical interaction ComPPI
JAK1 SIRT1 25348397 N/A physical interaction ComPPI
JAK1 EGFR 25348397 N/A physical interaction ComPPI
JAK1 TOP1 25348397 N/A physical interaction ComPPI
JAK1 MAGOH 25348397 N/A physical interaction ComPPI
JAK1 SMURF1 25348397 N/A physical interaction ComPPI
JAK1 HSP90AA2P 25348397 N/A physical interaction ComPPI
JAK1 PLCG1 25348397 N/A physical interaction ComPPI
JAK1 MDM2 25348397 N/A physical interaction ComPPI
JAK1 NOC2L 25348397 N/A physical interaction ComPPI
JAK1 PML 25348397 N/A physical interaction ComPPI
JAK1 TAGLN 25348397 N/A physical interaction ComPPI
JAK1 DTX3L 25348397 N/A physical interaction ComPPI
JAK1 DSP 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK1 FLG2 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK1 RNF125 25348397 N/A physical interaction ComPPI
JAK1 LPAR6 25348397 N/A physical interaction ComPPI
JAK1 CTDSPL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK1 TENT5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK1 KIF24 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK1 EID1 25348397 N/A physical interaction ComPPI
JAK1 CFTR 25348397 N/A physical interaction ComPPI
JAK1 LAMP2 25348397 N/A physical interaction ComPPI
JAK1 LAMP3 25348397 N/A physical interaction ComPPI
JAK1 IL13RA2 25348397 N/A physical interaction ComPPI
JAK1 MANSC1 25348397 N/A physical interaction ComPPI
JAK1 APLNR 25348397 N/A physical interaction ComPPI
JAK1 MAS1 25348397 N/A physical interaction ComPPI
JAK1 HAVCR2 25348397 N/A physical interaction ComPPI
JAK1 SLC15A1 25348397 N/A physical interaction ComPPI
JAK1 LRRIQ1 25348397 N/A physical interaction ComPPI
JAK1 CYLD 25348397 N/A physical interaction ComPPI
JAK1 USP6 25348397 N/A physical interaction ComPPI
JAK1 IFNLR1 25348397 N/A light scattering,molecular sieving,pull down,x-ray crystallography,physical interaction,bio-layer interferometry ComPPI
JAK1 IL6R 11557047 24234451 25348397 physical association coimmunoprecipitation ComPPI,IntAct
JAK1 JAK2 24234451 25348397 26175413 colocalization,physical association anti bait coimmunoprecipitation,confocal microscopy ComPPI,IntAct
EIF4A3 JAK1 25348397 N/A physical interaction ComPPI
IGF1R JAK1 14525934 25348397 9492017 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JAK1 JAK1 14525934 9597132 N/A experimental interaction detection HPRD
AGTR1 JAK1 24234451 28298427 physical association ubiquitin reconstruction IntAct
HNRNPD JAK1 24234451 30021884 physical association cross-linking study IntAct
SPTAN1 JAK1 24234451 30021884 physical association cross-linking study IntAct
JAK1 PLCG2 14978237 27898060 N/A N/A OmniPath
EGFR JAK1 15284024 27898060 stimulant N/A OmniPath
JAK1 EGFR 15284024 27898060 N/A N/A OmniPath
SOCS3 JAK1 10373548 10707961 16459330 27898060 inhibition,stimulant N/A OmniPath
JAK1 SOCS3 10373548 10707961 16459330 27898060 stimulant N/A OmniPath
IFNGR1 JAK1 12040185 12133952 15864272 17063185 19041276 21689637 27898060 7615558 7796299 8232552 8550631 8649432 stimulant N/A OmniPath
JAK1 IFNGR1 12133952 15864272 17063185 19041276 21689637 27898060 7615558 7796299 8156998 8232552 8550631 8649432 stimulant N/A OmniPath
JAK1 STAT6 10856136 23124025 27898060 9045682 9852261 inhibition,stimulant N/A OmniPath
CSF3R JAK1 27898060 7512720 stimulant N/A OmniPath
PTPN2 JAK1 11909529 15588985 15780598 27898060 inhibition,stimulant N/A OmniPath
EIF2AK2 JAK1 17290288 23236554 27898060 N/A N/A OmniPath
JAK1 EIF2AK2 17290288 23236554 27898060 N/A N/A OmniPath
JAK1 JAK3 10825200 12207328 12559972 17259970 27898060 9553136 stimulant N/A OmniPath
JAK3 JAK1 10825200 11641425 11909529 12207328 12559972 15007081 15659558 17259970 19901323 20135364 27898060 9553136 inhibition,stimulant N/A OmniPath
SOCS1 JAK1 10201892 1113376 11133764 15456882 23663276 23990909 27898060 9202126 inhibition,stimulant N/A OmniPath
IL7R JAK1 15996891 18445337 20167604 27898060 8647212 stimulant N/A OmniPath
IL6ST JAK1 11468294 11742534 12487370 21220115 23663276 24710148 27898060 9388212 stimulant N/A OmniPath
JAK1 STAT5A 10781830 11722592 16741510 27898060 9047382 stimulant N/A OmniPath
JAK1 IRS1 11162588 11591769 27898060 7499365 7544789 8756628 9233603 9492017 stimulant N/A OmniPath
IRS1 JAK1 11162588 27898060 7499365 9233603 9492017 stimulant N/A OmniPath
JAK1 MAP3K5 19287004 27898060 stimulant N/A OmniPath
PTPN6 JAK1 14624462 27898060 7629131 8524272 9520455 9852037 inhibition,stimulant N/A OmniPath
JAK1 STAT1 10918587 10982844 11294897 11438544 11722592 11823427 11839738 12040185 12637327 12817007 14963018 14978237 15284024 15322115 15978943 19088846 19534553 27898060 7532278 7543024 7657660 7690989 9020188 stimulant N/A OmniPath
JAK1 IL10RA 10433356 12133952 12374810 27898060 N/A N/A OmniPath
IL10RA JAK1 10347215 10433356 12133952 12374810 12974481 26260587 27898060 stimulant N/A OmniPath
IFNAR1 JAK1 15120645 27898060 8524272 9334213 stimulant N/A OmniPath
JAK1 IFNAR1 15120645 27898060 8524272 9334213 N/A N/A OmniPath
LEPR JAK1 16173077 27898060 stimulant N/A OmniPath
JAK1 TYK2 19901323 27898060 7504784 7589562 8702790 stimulant N/A OmniPath
TYK2 JAK1 27898060 7504784 7589562 8702790 N/A N/A OmniPath
JAK1 IRS2 11591769 27898060 7499365 9233603 stimulant N/A OmniPath
IRS2 JAK1 27898060 7499365 9233603 N/A N/A OmniPath
JAK1 STAT2 12040185 27898060 9020188 stimulant N/A OmniPath
JAK1 SHC1 27898060 9670964 stimulant N/A OmniPath
GHR JAK1 10502458 27898060 stimulant N/A OmniPath
IFNB1 JAK1 10918594 27898060 stimulant N/A OmniPath
JAK1 PTPN11 11036942 12270932 12403768 27898060 8790359 8995399 stimulant N/A OmniPath
PTPN11 JAK1 11036942 12270932 12403768 27898060 8790359 8995399 inhibition N/A OmniPath
TNFRSF1A JAK1 11801527 15173123 27898060 9510175 N/A N/A OmniPath
ISG15 JAK1 14668806 27898060 stimulant N/A OmniPath
MTOR JAK1 15659558 27898060 N/A N/A OmniPath
JAK1 STAT3 10918587 11294897 11350938 11722592 11751884 11940572 12040185 12244095 12576423 12626508 14551213 15284024 16497976 17016520 17389395 19723038 19901323 21690253 24710148 26260587 27898060 8272872 8626374 9566874 inhibition,stimulant N/A OmniPath
JAK1 IL4R 12133952 12223527 12242343 27898060 7929391 stimulant N/A OmniPath
IL4R JAK1 12133952 12223527 12242343 12704343 17312100 23124025 27898060 7929391 stimulant N/A OmniPath
JAK2 JAK1 27898060 7504784 stimulant N/A OmniPath
JAK1 JAK2 27898060 7504784 stimulant N/A OmniPath
TIRAP JAK1 21903422 27898060 N/A N/A OmniPath
JAK1 STAT5B 10781830 16741510 27898060 9047382 stimulant N/A OmniPath
IL2RG JAK1 27898060 7721895 7973658 stimulant N/A OmniPath
IL20RA JAK1 12941475 15120645 27898060 stimulant N/A OmniPath
JAK1 IFNGR2 19041276 27898060 stimulant N/A OmniPath
IFNGR2 JAK1 15120645 27898060 stimulant N/A OmniPath
IL2RB JAK1 10373548 12133952 24737791 27898060 7973657 7973658 7973659 8041779 8700888 9553136 9774657 stimulant N/A OmniPath
JAK1 IL2RB 10373548 12133952 27898060 7973657 7973658 7973659 8041779 8700888 9553136 9774657 N/A N/A OmniPath
JAK1 IL9R 27898060 8756628 9535918 N/A N/A OmniPath
IL9R JAK1 27898060 8756628 9535918 stimulant N/A OmniPath
IL20RB JAK1 12941475 27898060 stimulant N/A OmniPath
PLA2G4A JAK1 27898060 8612580 N/A N/A OmniPath
IL22RA1 JAK1 12941475 15120645 27898060 stimulant N/A OmniPath
PTPRC JAK1 11201744 11994288 1199429 27898060 inhibition,stimulant N/A OmniPath
JAK1 IL21R 11016959 1141862 11418623 27898060 N/A N/A OmniPath
IL21R JAK1 11016959 1141862 11418623 12093291 27898060 stimulant N/A OmniPath
JAK1 IFNAR2 12133952 16710296 27898060 7988557 9334213 N/A N/A OmniPath
IFNAR2 JAK1 12133952 16710296 27898060 7988557 9334213 stimulant N/A OmniPath
IL31RA JAK1 18926762 27898060 stimulant N/A OmniPath
IFNLR1 JAK1 15120645 27898060 stimulant N/A OmniPath

Visualization










  Return