Gene Information gene info

  1. Home

GENE：JAK3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol JAK3
FullNmae Janus kinase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6193
EnsembleID ENSG00000105639
Uniprot P52333

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
JAK3 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
JAK3 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
JAK3 necroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
JAK3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
JAK3 GO:0002250,GO:0002731,GO:0004713,GO:0004713,GO:0004713,GO:0004713,GO:0004715,GO:0005131,GO:0005515,GO:0005524,GO:0005768,GO:0005829,GO:0005829,GO:0005856,GO:0005886,GO:0006468,GO:0007167,GO:0007259,GO:0007260,GO:0018108,GO:0019221,GO:0019897,GO:0019903,GO:0030154,GO:0030183,GO:0031234,GO:0031234,GO:0032693,GO:0032695,GO:0035556,GO:0035556,GO:0035723,GO:0035771,GO:0038110,GO:0038110,GO:0038113,GO:0042981,GO:0043029,GO:0043029,GO:0045087,GO:0045221,GO:0045626,GO:0046425,GO:0050868,GO:0060397,GO:0060397,GO:0070232,GO:0070244,GO:0070669,GO:0070670,GO:0070672,GO:0071104

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
JAK3 hsa:3718 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
JAK3 hsa:3718 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
JAK3 hsa:3718 path:hsa04217 Necroptosis - Homo sapiens (human)
JAK3 hsa:3718 path:hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)
JAK3 hsa:3718 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)
JAK3 hsa:3718 path:hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human)
JAK3 hsa:3718 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
JAK3 hsa:3718 path:hsa05161 Hepatitis B - Homo sapiens (human)
JAK3 hsa:3718 path:hsa05162 Measles - Homo sapiens (human)
JAK3 hsa:3718 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
JAK3 hsa:3718 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
JAK3 hsa:3718 path:hsa05200 Pathways in cancer - Homo sapiens (human)
JAK3 hsa:3718 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)
JAK3 hsa:3718 path:hsa05223 Non-small cell lung cancer - Homo sapiens (human)
JAK3 hsa:3718 path:hsa05340 Primary immunodeficiency - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
JAK3 VIL1 17537734 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
IL4R JAK3 12207328 23180781 23331499 7538655 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink
JAK3 IL2RG 10629052 23180781 7973657 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
IL2RB JAK3 23180781 7973657 physical association anti tag coimmunoprecipitation InnateDB
JAK3 JAK1 12207328 23180781 physical association anti tag coimmunoprecipitation InnateDB
JAK3 JAK2 12207328 23180781 physical association anti tag coimmunoprecipitation InnateDB
TYK2 JAK3 12207328 23180781 physical association anti tag coimmunoprecipitation InnateDB
JAK3 STAT3 10037026 11406370 12207328 12495636 12934099 18988627 23109003 23180781 23331499 stimulation,physical association,chemical activation reaction anti tag coimmunoprecipitation InnateDB,SignaLink,SignaLink,SignaLink
JAK3 STAT6 12207328 23180781 physical association anti tag coimmunoprecipitation InnateDB
JAK3 JAK3 10629052 15121872 23180781 phosphorylation reaction in-gel kinase assay InnateDB
JAK3 IRS1 23180781 9233603 physical association anti tag coimmunoprecipitation InnateDB
JAK3 SOCS3 15385932 23180781 physical association anti tag coimmunoprecipitation InnateDB
JAK3 CD40 23180781 9133417 physical association anti tag coimmunoprecipitation,pull down InnateDB
IL7R JAK3 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
JAK3 CXCR4 10506573 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKG JAK3 20098747 23180781 physical association protein array InnateDB
JAK3 STAT5A 23331499 7777534 stimulation N/A SignaLink,SignaLink
JAK3 STAT1 11406370 12495636 23109003 23331499 9535918 stimulation,chemical activation reaction N/A SignaLink,SignaLink,SignaLink
PTPN6 JAK3 11021818 18988627 23331499 9520455 stimulation N/A SignaLink,SignaLink
PTPRC JAK3 11994288 23331499 stimulation N/A SignaLink,SignaLink
JAK3 PTK2B 21071413 23331499 9512511 stimulation N/A SignaLink,SignaLink
IL2RG JAK3 23331499 7973658 7973659 stimulation N/A SignaLink
PTPN11 JAK3 23331499 8766559 stimulation N/A SignaLink
JAK3 STAM 23331499 9133424 stimulation N/A SignaLink
IL9R JAK3 23331499 9535918 stimulation N/A SignaLink
JAK3 DBP 23331499 9852261 stimulation N/A SignaLink
JAK1 JAK3 10825200 23331499 stimulation N/A SignaLink
IL21R JAK3 12093291 23331499 stimulation N/A SignaLink
PTPN2 JAK3 15780598 23331499 stimulation N/A SignaLink
JAK3 STAT2 11406370 12495636 23109003 chemical activation reaction N/A SignaLink
JAK3 STAT5B 11406370 12495636 23109003 chemical activation reaction N/A SignaLink
CCR5 JAK3 11406370 12495636 17169327 23109003 chemical activation reaction N/A SignaLink
CXCR4 JAK3 11406370 12495636 17169327 23109003 chemical activation reaction N/A SignaLink

Source Target Pmid Interactiontype Methods Database
IRS1 JAK3 20005715 interaction type N/A PSP,SignaLink
IRS2 JAK3 18988627 20005715 7499365 interaction type N/A PSP,SignaLink
PIK3R1 JAK3 20005715 interaction type N/A PSP,SignaLink
SH2B2 JAK3 20005715 interaction type N/A PSP
SHB JAK3 12200137 18988627 20005715 interaction type N/A PSP,SignaLink
SOCS1 JAK3 20005715 interaction type N/A PSP
SOCS3 JAK3 20005715 interaction type N/A PSP
STAM JAK3 10899310 18988627 20005715 interaction type N/A PSP,SignaLink
SH2B2 JAK3 10872802 18988627 20005715 20005715 N/A N/A SignaLink
SOCS1 JAK3 11133764 18988627 20005715 20005715 N/A N/A SignaLink
SOCS3 JAK3 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 JAK3 12794134 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
ETS2 JAK3 12794134 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 JAK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA JAK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF JAK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 JAK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A JAK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
JUN JAK3 N/A trascriptional regulation,stimulation inferred by curator TFlink
SP1 JAK3 N/A trascriptional regulation,stimulation inferred by curator TFlink
STAT1 JAK3 N/A trascriptional regulation,stimulation inferred by curator TFlink
STAT3 JAK3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 JAK3 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00004818BD JAK3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C JAK3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001123BD JAK3 25416803 27063186 mrna cleavage,inhibition western blot TarBase

Source Target Pmid Interactiontype Methods Database
JAK3 PLD2 22135298 phosphorylation N/A PhosphoSite
JAK3 EZH2 22135298 phosphorylation N/A PhosphoSite
JAK3 NFATC1 22135298 phosphorylation N/A PhosphoSite
JAK3 JAK3 22135298 phosphorylation N/A PhosphoSite
JAK3 STAT5A 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
JAK3 JAK1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
JAK3 SIGLEC10 22135298 phosphorylation N/A PhosphoSite
JAK3 ELAVL1 22135298 phosphorylation N/A PhosphoSite
JAK3 STAT1 22135298 phosphorylation N/A PhosphoSite
IRS2 JAK3 25361965 interaction type N/A PTMCode2
JAK3 IRS2 25361965 interaction type N/A PTMCode2
IL13RA1 JAK3 25361965 interaction type N/A PTMCode2
JAK3 IL13RA1 25361965 interaction type N/A PTMCode2
STAT3 JAK3 25361965 interaction type N/A PTMCode2
JAK3 STAT3 25361965 interaction type N/A PTMCode2
FES JAK3 25361965 interaction type N/A PTMCode2
JAK3 FES 25361965 interaction type N/A PTMCode2
CBLB JAK3 25361965 interaction type N/A PTMCode2
JAK3 CBLB 25361965 interaction type N/A PTMCode2
IL7R JAK3 25361965 interaction type N/A PTMCode2
JAK3 IL7R 25361965 interaction type N/A PTMCode2
STAM JAK3 25361965 interaction type N/A PTMCode2
JAK3 STAM 25361965 interaction type N/A PTMCode2
IFNGR2 JAK3 25361965 interaction type N/A PTMCode2
JAK3 IFNGR2 25361965 interaction type N/A PTMCode2
CXCR4 JAK3 25361965 interaction type N/A PTMCode2
JAK3 CXCR4 25361965 interaction type N/A PTMCode2
CD40 JAK3 25361965 interaction type N/A PTMCode2
JAK3 CD40 25361965 interaction type N/A PTMCode2
LCK JAK3 25361965 interaction type N/A PTMCode2
JAK3 LCK 25361965 interaction type N/A PTMCode2
IL2RG JAK3 25361965 interaction type N/A PTMCode2
JAK3 IL2RG 25361965 interaction type N/A PTMCode2
PTPRC JAK3 25361965 interaction type N/A PTMCode2
JAK3 PTPRC 25361965 interaction type N/A PTMCode2
PTK2B JAK3 25361965 interaction type N/A PTMCode2
JAK3 PTK2B 25361965 interaction type N/A PTMCode2
IL4R JAK3 25361965 interaction type N/A PTMCode2
JAK3 IL4R 25361965 interaction type N/A PTMCode2
GHR JAK3 25361965 interaction type N/A PTMCode2
JAK3 GHR 25361965 interaction type N/A PTMCode2
LEPR JAK3 25361965 interaction type N/A PTMCode2
JAK3 LEPR 25361965 interaction type N/A PTMCode2
ALK JAK3 25361965 interaction type N/A PTMCode2
JAK3 ALK 25361965 interaction type N/A PTMCode2
STAM2 JAK3 25361965 interaction type N/A PTMCode2
JAK3 STAM2 25361965 interaction type N/A PTMCode2
STAT5A JAK3 25361965 interaction type N/A PTMCode2
CD247 JAK3 25361965 interaction type N/A PTMCode2
JAK3 CD247 25361965 interaction type N/A PTMCode2
JAK1 JAK3 25361965 interaction type N/A PTMCode2
EPOR JAK3 25361965 interaction type N/A PTMCode2
JAK3 EPOR 25361965 interaction type N/A PTMCode2
PTPN6 JAK3 25361965 interaction type N/A PTMCode2
JAK3 PTPN6 25361965 interaction type N/A PTMCode2
IRS1 JAK3 25361965 interaction type N/A PTMCode2
JAK3 IRS1 25361965 interaction type N/A PTMCode2
PIK3R1 JAK3 25361965 interaction type N/A PTMCode2
JAK3 PIK3R1 25361965 interaction type N/A PTMCode2
PTPN2 JAK3 25361965 interaction type N/A PTMCode2
JAK3 PTPN2 25361965 interaction type N/A PTMCode2
SOCS3 JAK3 25361965 interaction type N/A PTMCode2
JAK3 SOCS3 25361965 interaction type N/A PTMCode2
IL2RB JAK3 25361965 interaction type N/A PTMCode2
JAK3 IL2RB 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NMI JAK3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SOCS3 JAK3 10373548 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TYK2 JAK3 25348397 N/A physical interaction ComPPI
PTPN6 JAK3 14525934 25348397 9520455 N/A experimental interaction detection,in vitro ComPPI,HPRD
GTF2B JAK3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MRPL23 JAK3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GEMIN6 JAK3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHB JAK3 12200137 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTK2B JAK3 14525934 25348397 9512511 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SOCS1 JAK3 11133764 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
KIT JAK3 25348397 N/A physical interaction ComPPI
PIK3R1 JAK3 14525934 25348397 7662955 N/A experimental interaction detection,in vivo ComPPI,HPRD
CD81 JAK3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LCK JAK3 11278738 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SH2B2 JAK3 10872802 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
INPP5D JAK3 10875931 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
NFATC1 JAK3 23263556 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
ARAF JAK3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KHDRBS1 JAK3 14525934 24234451 25348397 9045636 physical association coimmunoprecipitation,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
TAF1 JAK3 25348397 N/A physical interaction ComPPI
FES JAK3 11160325 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
IRS2 JAK3 14525934 25348397 7499365 N/A experimental interaction detection,in vivo ComPPI,HPRD
CD3E JAK3 25348397 N/A physical interaction ComPPI
APOA1 JAK3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
JAK1 JAK3 12559972 14525934 25348397 9553136 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN2 JAK3 25348397 N/A in vitro,in vivo ComPPI
CSNK1E JAK3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LEPR JAK3 11585385 24234451 25348397 association coimmunoprecipitation,physical interaction ComPPI,IntAct
STAT5A JAK3 10037026 14525934 25348397 9047382 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
STAT5B JAK3 25348397 N/A physical interaction ComPPI
PRMT5 JAK3 10531356 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
STAM2 JAK3 10899310 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CD247 JAK3 11349123 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TUBA4A JAK3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UHRF2 JAK3 21952639 24234451 25348397 physical association physical interaction,antibody array ComPPI,IntAct
UBR5 JAK3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PKM JAK3 25348397 N/A protein kinase assay ComPPI
RAB11A JAK3 25348397 N/A physical interaction ComPPI
JAK3 IL2RG 14525934 25348397 7973658 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK3 STAM 10899310 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JAK3 TIAF1 10733938 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
JAK3 STAT3 10037026 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK3 IL7R 14525934 15996891 25348397 7481769 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK3 CD40 10395671 14525934 25348397 9133417 N/A experimental interaction detection,in vitro ComPPI,HPRD
JAK3 VIL1 14525934 17537734 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
JAK3 IL2RB 10825200 14525934 25348397 7973659 9553136 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
JAK3 IRS1 14525934 25348397 7499365 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK3 IL4R 14525934 25348397 7538655 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK3 JAK2 11585385 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK3 PTPRC 25348397 N/A in vitro ComPPI
JAK3 CXCR4 10506573 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK3 ALK 11850821 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JAK3 IKBKG 20098747 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
JAK3 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
JAK3 STAT6 25348397 N/A physical interaction ComPPI
JAK3 CDK1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
JAK3 BAG2 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 CCT2 25348397 N/A physical interaction ComPPI
JAK3 CCT3 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 CCT4 24234451 25348397 25852190 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 CCT6A 24234451 25348397 25852190 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 CCT8 24234451 25348397 25852190 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 GNAS 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 GNAS 25348397 N/A physical interaction ComPPI
JAK3 GNAS 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 GPATCH8 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 MAGED2 24234451 25348397 25852190 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 NAP1L1 24234451 25348397 25852190 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 NAP1L4 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 RNPS1 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 SRRM2 25348397 N/A physical interaction ComPPI
JAK3 TUBB1 25348397 N/A physical interaction ComPPI
JAK3 CDK4 25348397 N/A physical interaction ComPPI
JAK3 LNX1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
JAK3 CAPN2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 CENPC 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 CRY1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 DECR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 INPP5B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 DHX16 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 WDR46 25348397 N/A physical interaction ComPPI
JAK3 STUB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 SPTLC1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 MTF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 RAB11FIP2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 TNPO3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 CCNL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 LYSMD2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 RAB11B 24234451 25348397 26496610 association anti tag coimmunoprecipitation ComPPI,IntAct
TCP1 JAK3 24234451 25348397 25852190 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COX4I1 JAK3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JAK3 JAK3 14525934 15121872 9391116 N/A experimental interaction detection HPRD
CXCR4 JAK3 10506573 27898060 stimulant N/A OmniPath
SOCS3 JAK3 10373548 15385932 21508344 27898060 inhibition N/A OmniPath
JAK3 SOCS3 10373548 15385932 27898060 stimulant N/A OmniPath
JAK3 STAT6 12207328 27898060 inhibition N/A OmniPath
PTPN2 JAK3 11909529 15588985 15780598 27898060 inhibition,stimulant N/A OmniPath
SOCS1 JAK3 11133764 21508344 27898060 inhibition N/A OmniPath
IL7R JAK3 15996891 20167604 27898060 7481769 7535338 stimulant N/A OmniPath
JAK3 STAT5A 10037026 11046040 11254359 11641791 12060651 12456798 12879454 14522994 15256422 15604220 18250158 18394554 18394555 19061839 19088846 19923221 20622007 21716071 22442148 26152718 27898060 7777534 9047382 9573010 9813040 stimulant N/A OmniPath
IRS1 JAK3 27898060 7499365 9233603 N/A N/A OmniPath
IKBKG JAK3 20098747 27898060 N/A N/A OmniPath
PTPN6 JAK3 11021818 27898060 9520455 inhibition,stimulant N/A OmniPath
JAK3 STAT1 27898060 9535918 stimulant N/A OmniPath
JAK1 JAK3 10825200 12207328 12559972 17259970 27898060 9553136 stimulant N/A OmniPath
JAK3 JAK1 10825200 11641425 11909529 12207328 12559972 15007081 15659558 17259970 19901323 20135364 27898060 9553136 inhibition,stimulant N/A OmniPath
JAK3 TYK2 12207328 27898060 N/A N/A OmniPath
JAK3 SHC1 24795043 27898060 stimulant N/A OmniPath
PTPN11 JAK3 27898060 8766559 stimulant N/A OmniPath
JAK3 CD40 10395671 27898060 9133417 N/A N/A OmniPath
JAK3 STAT3 10037026 12207328 129341 27898060 stimulant N/A OmniPath
IL4R JAK3 12207328 17312100 27898060 7538655 stimulant N/A OmniPath
JAK3 JAK2 11585385 12207328 27898060 N/A N/A OmniPath
IL2RG JAK3 10629052 18445337 27898060 7973657 7973658 7973659 stimulant N/A OmniPath
JAK3 IL2RG 10629052 27898060 7973657 7973658 7973659 N/A N/A OmniPath
JAK3 PLD2 20176813 21414324 23378025 27898060 stimulant N/A OmniPath
JAK3 NFATC1 23263556 24465763 27898060 N/A N/A OmniPath
IL2RB JAK3 10825200 27898060 7973657 7973659 9553136 N/A N/A OmniPath
IL9R JAK3 27898060 9535918 stimulant N/A OmniPath
JAK3 SIGLEC10 11733002 27898060 stimulant N/A OmniPath
VIL1 JAK3 17537734 27898060 N/A N/A OmniPath
JAK3 VIL1 17537734 27898060 N/A N/A OmniPath
JAK3 STAM 10899310 27898060 9133424 stimulant N/A OmniPath
JAK3 PTK2B 27898060 9512511 stimulant N/A OmniPath
PTPRC JAK3 11994288 27898060 stimulant N/A OmniPath
IL21R JAK3 12093291 27898060 stimulant N/A OmniPath

Visualization










  Return