GENE:STAT5A
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | STAT5A |
| FullNmae | signal transducer and activator of transcription 5A |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:11366 |
| EnsembleID | ENSG00000126561 |
| Uniprot | P42229 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| STAT5A | necroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| STAT5A | necroptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| STAT5A | GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001938,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0005829,GO:0006357,GO:0006952,GO:0007259,GO:0007259,GO:0007595,GO:0019221,GO:0019530,GO:0030222,GO:0035723,GO:0035771,GO:0038026,GO:0038043,GO:0038110,GO:0038113,GO:0038156,GO:0040014,GO:0042127,GO:0043434,GO:0043536,GO:0045944,GO:0060397,GO:0090575,GO:0140297 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| STAT5A | hsa:6776 | path:hsa04012 | ErbB signaling pathway - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa04217 | Necroptosis - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa04630 | JAK-STAT signaling pathway - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa04658 | Th1 and Th2 cell differentiation - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa04659 | Th17 cell differentiation - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa04917 | Prolactin signaling pathway - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa04933 | AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa04935 | Growth hormone synthesis, secretion and action - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa05161 | Hepatitis B - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa05162 | Measles - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa05166 | Human T-cell leukemia virus 1 infection - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa05200 | Pathways in cancer - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa05203 | Viral carcinogenesis - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa05207 | Chemical carcinogenesis - receptor activation - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa05220 | Chronic myeloid leukemia - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa05221 | Acute myeloid leukemia - Homo sapiens (human) |
| STAT5A | hsa:6776 | path:hsa05223 | Non-small cell lung cancer - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| STAT5A | BTK | 11413148 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | POU2F1 | 14645506 23180781 | physical association | anti tag coimmunoprecipitation,gst pull down | InnateDB |
| STAT5A | CCND1 | 14645506 23180781 | physical association | affinity chromatography technology | InnateDB |
| KIT | STAT5A | 10358045 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5B | STAT5A | 10358045 23180781 9398404 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | STAT1 | 10358045 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | STAT3 | 23180781 9398404 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | CTLA4 | 16476059 23180781 | physical association | two hybrid | InnateDB |
| TYK2 | STAT5A | 23180781 23331499 9872990 | stimulation,physical association | anti tag coimmunoprecipitation | InnateDB,SignaLink |
| CRKL | STAT5A | 23180781 9872990 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | PTPN1 | 12237455 23180781 | dephosphorylation reaction,physical association | peptide array | InnateDB |
| CISH | STAT5A | 11713228 15652752 23180781 23331499 9742102 | stimulation,physical association | electrophoretic mobility supershift assay | InnateDB,SignaLink,SignaLink |
| IL2RA | STAT5A | 23180781 8896456 | physical association | electrophoretic mobility supershift assay | InnateDB |
| IL5 | STAT5A | 15735688 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| IL9 | STAT5A | 15735688 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| CCND2 | STAT5A | 15735688 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | BCL6 | 19965633 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| IL7R | STAT5A | 10582086 18988627 20167604 23180781 23331499 7719938 | interaction type,physical association | anti tag coimmunoprecipitation | InnateDB,SignaLink,SignaLink |
| IL2RB | STAT5A | 21516110 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | TBX21 | 21516110 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| IRF1 | STAT5A | 21516110 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| MAF | STAT5A | 21876034 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | RELA | 12208876 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | MAP3K5 | 23180781 24497979 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | SSH2 | 23180781 24497979 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | SAMD4A | 23180781 24497979 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | ST3GAL1 | 23180781 24497979 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | PPP2R2B | 23180781 24497979 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | CBS | 23180781 24497979 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | DNAJC6 | 23180781 24497979 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | NDRG1 | 23180781 24497979 | physical association | anti tag coimmunoprecipitation | InnateDB |
| IL4R | STAT5A | 18820682 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | FOSL2 | 23180781 24587342 | physical association | anti tag coimmunoprecipitation | InnateDB |
| TBX21 | STAT5A | 23180781 23232398 | physical association | anti tag coimmunoprecipitation | InnateDB |
| GATA3 | STAT5A | 23180781 23232398 | physical association | anti tag coimmunoprecipitation | InnateDB |
| STAT5A | STK11 | 23180781 24913037 | physical association | anti tag coimmunoprecipitation | InnateDB |
| LYN | STAT5A | 11007921 22509308 29145629 7608147 7744007 8861946 9057652 9587401 9657743 9722506 9837784 9923445 | physical association | inferred by curator | Reactome |
| STAT5A | STAT5A | 10358045 11007921 11448122 11494148 11728342 15749844 22509308 24243840 29145629 7608147 7744007 8702919 8861946 9057652 9355737 9398404 9587401 9657743 9685210 9722506 9837784 9923445 | physical association | inferred by curator | Reactome |
| STAT5A | IRS2 | 11007921 22509308 29145629 7608147 7744007 8861946 9057652 9587401 9657743 9722506 9837784 9923445 | physical association | inferred by curator | Reactome |
| STAT5A | STAT5B | 10358045 11007921 11448122 11494148 11728342 15749844 22509308 24243840 29145629 7608147 7744007 8702919 8861946 9057652 9355737 9398404 9587401 9657743 9685210 9722506 9837784 9923445 | physical association | inferred by curator | Reactome |
| GH1 | STAT5A | 24243840 29145629 | physical association | inferred by curator | Reactome |
| GH2 | STAT5A | 24243840 29145629 | physical association | inferred by curator | Reactome |
| GHR | STAT5A | 10582086 23331499 24243840 29145629 | interaction type,physical association | inferred by curator | Reactome,SignaLink,SignaLink |
| IL7 | STAT5A | 19864382 29145629 7489741 7719938 8709637 9715265 | physical association | inferred by curator | Reactome |
| JAK1 | STAT5A | 19864382 29145629 7489741 7719938 8709637 8756628 9535918 9715265 | physical association | inferred by curator | Reactome |
| PRLR | STAT5A | 10582086 23331499 24243840 29145629 | stimulation,physical association | inferred by curator | Reactome,SignaLink,SignaLink |
| CSH1 | STAT5A | 24243840 29145629 | physical association | inferred by curator | Reactome |
| PRL | STAT5A | 24243840 29145629 | physical association | inferred by curator | Reactome |
| STAT3 | STAT5A | 10358045 11494148 12623850 24243840 29145629 9355737 | physical association | inferred by curator | Reactome |
| STAT1 | STAT5A | 10358045 11494148 24243840 29145629 9355737 | physical association | inferred by curator | Reactome |
| JAK3 | STAT5A | 23331499 7777534 | stimulation | N/A | SignaLink,SignaLink |
| SOCS3 | STAT5A | 11331873 23331499 | stimulation | N/A | SignaLink,SignaLink |
| JAK2 | STAT5A | 11413148 15795318 18988627 21071413 23331499 7925280 8617237 9575217 | stimulation | N/A | SignaLink,SignaLink |
| ERBB4 | STAT5A | 16729043 23331499 | stimulation | N/A | SignaLink,SignaLink |
| MAPK3 | STAT5A | 10194762 17502367 18988627 23331499 | stimulation | N/A | SignaLink,SignaLink |
| CRLF2 | STAT5A | 10582086 23331499 | stimulation | N/A | SignaLink,SignaLink |
| IL15RA | STAT5A | 10582086 23331499 | stimulation | N/A | SignaLink,SignaLink |
| IL3RA | STAT5A | 10582086 23331499 | stimulation | N/A | SignaLink,SignaLink |
| SIRT1 | STAT5A | 23980167 | deacetylation reaction,inhibition | N/A | SignaLink |
| PTPN2 | STAT5A | 11773439 23331499 | stimulation | N/A | SignaLink |
| EGFR | STAT5A | 10358079 16729043 23331499 | stimulation | N/A | SignaLink |
| IL2RG | STAT5A | 10582086 23331499 | interaction type | N/A | SignaLink |
| IL9R | STAT5A | 10582086 23331499 | stimulation | N/A | SignaLink |
| IL5RA | STAT5A | 10582086 23331499 | stimulation | N/A | SignaLink |
| CSF2RA | STAT5A | 10582086 23331499 | stimulation | N/A | SignaLink |
| EPOR | STAT5A | 10582086 23331499 | interaction type | N/A | SignaLink |
| MPL | STAT5A | 10582086 23331499 | stimulation | N/A | SignaLink |
| PTPN11 | STAT5A | 10617656 12060651 12237455 18508557 23331499 | stimulation | N/A | SignaLink |
| THRB | STAT5A | 10976919 23331499 | stimulation | N/A | SignaLink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | STAT5A | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | STAT5A | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | STAT5A | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | STAT5A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | STAT5A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | STAT5A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | STAT5A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | STAT5A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | STAT5A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | STAT5A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | STAT5A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | STAT5A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PPARA | STAT5A | 21542777 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ESR1 | STAT5A | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ESR2 | STAT5A | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000153377 | STAT5A | 20489169 | rna interference,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
| URS0000153377 | STAT5A | 20489169 24736554 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS00000B7E30 | STAT5A | 24400121 25416803 | mrna cleavage,inhibition | quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS0000170CF4 | STAT5A | 24736554 25416803 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS00003E5E03 | STAT5A | 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | STAT5A | 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AA845 | STAT5A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000079D48 | STAT5A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000136174 | STAT5A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C0FCB | STAT5A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AB35 | STAT5A | 23313552 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000003E1A9 | STAT5A | 25241899 25416803 | mrna cleavage,inhibition | western blot,immunocytochemistry,miRNA interference luciferase reporter assay | TarBase |
| URS00001C3AC1 | STAT5A | 25416803 26923924 | mrna cleavage,inhibition | rna immunoprecipitation,miRNA interference luciferase reporter assay | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SYK | STAT5A | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
| MAPK3 | STAT5A | 22135298 | phosphorylation | N/A | PhosphoSite |
| SRC | STAT5A | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
| LCK | STAT5A | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
| MAPK1 | STAT5A | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
| JAK2 | STAT5A | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
| JAK3 | STAT5A | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
| HCK | STAT5A | 22135298 | phosphorylation | N/A | PhosphoSite |
| MERTK | STAT5A | 22135298 | phosphorylation | N/A | PhosphoSite |
| AXL | STAT5A | 22135298 | phosphorylation | N/A | PhosphoSite |
| IL7R | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | IL7R | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | LCK | 25361965 | interaction type | N/A | PTMCode2 |
| IL2RG | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | IL2RG | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | MAPK1 | 25361965 | interaction type | N/A | PTMCode2 |
| GHR | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | GHR | 25361965 | interaction type | N/A | PTMCode2 |
| PPIB | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | PPIB | 25361965 | interaction type | N/A | PTMCode2 |
| LEPR | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | LEPR | 25361965 | interaction type | N/A | PTMCode2 |
| CBL | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | CBL | 25361965 | interaction type | N/A | PTMCode2 |
| BMX | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | BMX | 25361965 | interaction type | N/A | PTMCode2 |
| CEBPB | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | CEBPB | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | ERBB4 | 25361965 | interaction type | N/A | PTMCode2 |
| ERBB4 | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | JAK1 | 25361965 | interaction type | N/A | PTMCode2 |
| JAK1 | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | CRKL | 25361965 | interaction type | N/A | PTMCode2 |
| CRKL | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | SRC | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | CD247 | 25361965 | interaction type | N/A | PTMCode2 |
| CD247 | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | PTPN1 | 25361965 | interaction type | N/A | PTMCode2 |
| PTPN1 | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | SYK | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | BRCA2 | 25361965 | interaction type | N/A | PTMCode2 |
| BRCA2 | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | JAK2 | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | JAK3 | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | SHC1 | 25361965 | interaction type | N/A | PTMCode2 |
| SHC1 | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| EPOR | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | EPOR | 25361965 | interaction type | N/A | PTMCode2 |
| NR3C1 | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | NR3C1 | 25361965 | interaction type | N/A | PTMCode2 |
| EGFR | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | EGFR | 25361965 | interaction type | N/A | PTMCode2 |
| KIT | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | KIT | 25361965 | interaction type | N/A | PTMCode2 |
| CRK | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | CRK | 25361965 | interaction type | N/A | PTMCode2 |
| STAP2 | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | STAP2 | 25361965 | interaction type | N/A | PTMCode2 |
| NMI | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | NMI | 25361965 | interaction type | N/A | PTMCode2 |
| PTPN2 | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | PTPN2 | 25361965 | interaction type | N/A | PTMCode2 |
| INSR | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | INSR | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | PTPN6 | 25361965 | interaction type | N/A | PTMCode2 |
| PTPN6 | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| IL2RB | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | IL2RB | 25361965 | interaction type | N/A | PTMCode2 |
| BTK | STAT5A | 25361965 | interaction type | N/A | PTMCode2 |
| STAT5A | BTK | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| FARS2 | STAT5A | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NMI | STAT5A | 14525934 24234451 25348397 9989503 | physical association | two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct |
| PPIB | STAT5A | 11997457 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| KRT83 | STAT5A | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| STAT1 | STAT5A | 10358045 14525934 24234451 25241761 25348397 | physical association | experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay | ComPPI,HPRD,IntAct |
| MAGEA12 | STAT5A | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| MRPS6 | STAT5A | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| CRK | STAT5A | 11097834 14525934 24234451 25241761 25348397 | physical association | experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay | ComPPI,HPRD,IntAct |
| NLK | STAT5A | 25348397 | N/A | physical interaction | ComPPI |
| CBL | STAT5A | 12193575 14525934 23533197 24234451 25348397 25814554 27898060 | physical association | two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo,validated two hybrid | ComPPI,HPRD,IntAct,OmniPath |
| MAPK1 | STAT5A | 10194762 10996427 14525934 24234451 25241761 25348397 | physical association | experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay | ComPPI,HPRD,IntAct |
| BTK | STAT5A | 11413148 14525934 25348397 7925280 8617237 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| SYK | STAT5A | 10825200 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| ERBB4 | STAT5A | 14525934 15534001 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| KIT | STAT5A | 10358045 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| PTPN11 | STAT5A | 10617656 12060651 12237455 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| SRC | STAT5A | 10358079 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| CRKL | STAT5A | 11167825 14525934 24234451 25348397 9837784 | association | experimental interaction detection,far western blotting,pull down,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| LCK | STAT5A | 10825200 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| SHC1 | STAT5A | 10996427 14525934 23397142 24234451 25348397 | physical association | experimental interaction detection,physical interaction,in vitro,proximity ligation assay | ComPPI,HPRD,IntAct |
| MAPK3 | STAT5A | 10194762 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| CREBBP | STAT5A | 24234451 25348397 9989503 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| RUNX2 | STAT5A | 25348397 | N/A | physical interaction | ComPPI |
| NCOA1 | STAT5A | 25348397 | N/A | physical interaction | ComPPI |
| EP300 | STAT5A | 14525934 14726487 21988832 24234451 25348397 9989503 | physical association | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| CEBPB | STAT5A | 11158330 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| FGFR2 | STAT5A | 25348397 | N/A | physical interaction | ComPPI |
| NCOR2 | STAT5A | 25348397 | N/A | two hybrid,in vitro,in vivo | ComPPI |
| PDGFRB | STAT5A | 14525934 24234451 25241761 25348397 9484840 | physical association | experimental interaction detection,molecular sieving,physical interaction,in vitro,proximity ligation assay | ComPPI,HPRD,IntAct |
| GHR | STAT5A | 14525934 24234451 25241761 25348397 8702683 | physical association | experimental interaction detection,physical interaction,in vivo,proximity ligation assay | ComPPI,HPRD,IntAct |
| AGAP2 | STAT5A | 25348397 | N/A | anti tag coimmunoprecipitation | ComPPI |
| PDGFRA | STAT5A | 14525934 25348397 9484840 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| SOCS7 | STAT5A | 25348397 | N/A | physical interaction | ComPPI |
| PRMT1 | STAT5A | 25348397 | N/A | physical interaction | ComPPI |
| JAK1 | STAT5A | 11722592 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| PTPN1 | STAT5A | 12237455 14525934 24234451 25348397 | dephosphorylation reaction | experimental interaction detection,filter binding,physical interaction,phosphatase assay,in vitro | ComPPI,HPRD,IntAct |
| PTPN2 | STAT5A | 25348397 | N/A | in vitro,in vivo | ComPPI |
| SMARCA4 | STAT5A | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | CD247 | 14525934 25348397 9880255 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| STAT5A | IL2RG | 11418623 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| STAT5A | JAK3 | 10037026 14525934 25348397 9047382 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD |
| STAT5A | BRCA2 | 12459499 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| STAT5A | ESR2 | 11682624 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| STAT5A | STAT5B | 14525934 25348397 9528750 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| STAT5A | TSLP | 10570284 11418668 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| STAT5A | CENPJ | 12198240 14525934 25348397 | N/A | two hybrid,experimental interaction detection,in vivo,two hybrid | ComPPI,HPRD |
| STAT5A | BRCA1 | 12459499 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| STAT5A | PRTFDC1 | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| STAT5A | IL7R | 14525934 25348397 7719938 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| STAT5A | STAT3 | 14525934 25348397 9398404 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| STAT5A | CCR5 | 10037796 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| STAT5A | INSR | 12456798 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| STAT5A | POU2F1 | 25348397 | N/A | in vitro,in vivo | ComPPI |
| STAT5A | PPP2CA | 11440634 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| STAT5A | CTLA4 | 14525934 16476059 24234451 25241761 25348397 | physical association | two hybrid,experimental interaction detection,physical interaction,in vivo,proximity ligation assay,two hybrid | ComPPI,HPRD,IntAct |
| STAT5A | STAP2 | 14525934 15611091 24234451 25348397 | colocalization,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,imaging technique,in vivo | ComPPI,HPRD,IntAct |
| STAT5A | EGFR | 10358079 14525934 24234451 24658140 25348397 | physical association | anti tag coimmunoprecipitation,experimental interaction detection,ubiquitin reconstruction,physical interaction,in vivo | ComPPI,HPRD,IntAct |
| STAT5A | EPOR | 14525934 15644415 25348397 8977232 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| STAT5A | ESR1 | 11682624 14525934 15304355 24234451 25348397 27898060 | physical association | coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct,OmniPath |
| STAT5A | NR3C1 | 14525934 25348397 9528750 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| STAT5A | IL2RB | 10602027 14525934 24234451 25348397 | association | experimental interaction detection,pull down,physical interaction,in vivo | ComPPI,HPRD,IntAct |
| STAT5A | JAK2 | 11413148 14525934 25348397 7925280 8617237 9575217 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| STAT5A | MAGEA3 | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | HDAC1 | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | CARM1 | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | PGR | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | GNB2 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| STAT5A | SQSTM1 | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | MYB | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | NFKB1 | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | CYP2C9 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| STAT5A | RBMX | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| STAT5A | AQP11 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| STAT5A | CSNK2B | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| STAT5A | EPAS1 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| STAT5A | FN1 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| STAT5A | GLUD1 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| STAT5A | UGT2B4 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| STAT5A | HELZ | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | TXNDC11 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| STAT5A | ZNF596 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| STAT5A | POM121B | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | POM121C | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| STAT5A | LEF1 | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | TCF12 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| STAT5A | PPARG | 18927468 23223023 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| STAT5A | NARF | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | OLIG1 | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array,validated two hybrid | ComPPI,IntAct |
| STAT5A | ADD3 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STAT5A | DLAT | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STAT5A | PDHA1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STAT5A | PDHB | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STAT5A | ICAM5 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STAT5A | PDHX | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STAT5A | GDF15 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STAT5A | RNF13 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STAT5A | R3HDM2 | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | ERMP1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STAT5A | ILKAP | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STAT5A | SPICE1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STAT5A | TLR2 | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | PDK2 | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | PDK3 | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | KLHL7 | 25348397 | N/A | physical interaction | ComPPI |
| STAT5A | ABL1 | 22286129 24234451 25348397 | phosphorylation reaction | phosphorylation reaction,protein kinase assay | ComPPI,IntAct |
| STAT5A | WASH2P | 21988832 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
| STAT5A | CSF2RB | 16437163 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| STAT5A | PTEN | 25348397 | N/A | genetic | ComPPI |
| CBX5 | STAT5A | 23733954 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| BMX | STAT5A | 14525934 25348397 9373245 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| STAT5A | TEK | 14525934 14726409 | N/A | experimental interaction detection | HPRD |
| STAT5A | STAT5A | 14525934 14704793 21988832 24234451 9528750 | physical association | experimental interaction detection,two hybrid array,two hybrid | HPRD,IntAct |
| SRC | STAT5A | 10358079 11641791 27898060 | stimulant | N/A | OmniPath |
| LYN | STAT5A | 11641791 27898060 | stimulant | N/A | OmniPath |
| PTPN1 | STAT5A | 10993888 12237455 27898060 | inhibition | N/A | OmniPath |
| EPOR | STAT5A | 10374881 10582086 15644415 27898060 8977232 | stimulant | N/A | OmniPath |
| EGFR | STAT5A | 10358079 16729043 18586824 24658140 25402006 27898060 | stimulant | N/A | OmniPath |
| PTEN | STAT5A | 20596030 27898060 | inhibition | N/A | OmniPath |
| IL3RA | STAT5A | 10582086 27898060 | stimulant | N/A | OmniPath |
| SOCS3 | STAT5A | 11331873 27898060 | inhibition,stimulant | N/A | OmniPath |
| CSF2RA | STAT5A | 10582086 27898060 | stimulant | N/A | OmniPath |
| PTPN2 | STAT5A | 11773439 15588985 15780598 27898060 | inhibition,stimulant | N/A | OmniPath |
| JAK3 | STAT5A | 10037026 11046040 11254359 11641791 12060651 12456798 12879454 14522994 15256422 15604220 18250158 18394554 18394555 19061839 19088846 19923221 20622007 21716071 22442148 26152718 27898060 7777534 9047382 9573010 9813040 | stimulant | N/A | OmniPath |
| STAT5A | BCL2L1 | 10652277 11085453 27898060 | stimulant | N/A | OmniPath |
| IL7R | STAT5A | 20167604 27898060 7719938 | stimulant | N/A | OmniPath |
| KIT | STAT5A | 10358045 27898060 | stimulant | N/A | OmniPath |
| IL5RA | STAT5A | 10582086 27898060 | stimulant | N/A | OmniPath |
| STAT1 | STAT5A | 10358045 25241761 27898060 | N/A | N/A | OmniPath |
| STAT5A | STAT1 | 10358045 25241761 27898060 | N/A | N/A | OmniPath |
| STAT5A | AURKA | 18586824 27898060 | stimulant | N/A | OmniPath |
| MAPK3 | STAT5A | 10194762 27898060 | stimulant | N/A | OmniPath |
| JAK1 | STAT5A | 10781830 11722592 16741510 27898060 9047382 | stimulant | N/A | OmniPath |
| STAT5A | BTK | 11413148 27898060 7925280 8617237 | N/A | N/A | OmniPath |
| BTK | STAT5A | 11413148 16497976 17016520 17389395 27898060 7925280 8617237 | N/A | N/A | OmniPath |
| TYK2 | STAT5A | 27898060 9872990 | stimulant | N/A | OmniPath |
| GHR | STAT5A | 10582086 25241761 27898060 8702683 | stimulant | N/A | OmniPath |
| STAT5A | CRKL | 11167825 27898060 9657743 9837784 9845531 9872990 | N/A | N/A | OmniPath |
| CRKL | STAT5A | 11167825 27898060 9657743 9837784 9845531 9872990 | N/A | N/A | OmniPath |
| NCOA1 | STAT5A | 12954634 27898060 | stimulant | N/A | OmniPath |
| EP300 | STAT5A | 14726487 15509516 21988832 27898060 9773981 9989503 | stimulant | N/A | OmniPath |
| MAPK1 | STAT5A | 10194762 10996427 25241761 27898060 | stimulant | N/A | OmniPath |
| ERBB4 | STAT5A | 15534001 16729043 22584572 27898060 | stimulant | N/A | OmniPath |
| PTPN11 | STAT5A | 10617656 12060651 12237455 18508557 27898060 | inhibition,stimulant | N/A | OmniPath |
| STAT5A | DNMT3A | 26059451 27898060 | stimulant | N/A | OmniPath |
| STAT5A | POU2F1 | 14645506 27898060 | N/A | N/A | OmniPath |
| STAT5A | CSN2 | 15534001 27898060 | stimulant | N/A | OmniPath |
| PRLR | STAT5A | 10582086 27898060 | stimulant | N/A | OmniPath |
| STAT5A | STAT3 | 27898060 9398404 | N/A | N/A | OmniPath |
| IL4R | STAT5A | 20824124 27898060 | stimulant | N/A | OmniPath |
| JAK2 | STAT5A | 11413148 11641791 12529425 15795318 16497976 17016520 17081983 17389395 18083107 18250158 19088846 19534553 27898060 7925280 8617237 9047382 9575217 | stimulant | N/A | OmniPath |
| MAPK8 | STAT5A | 19737086 27898060 | stimulant | N/A | OmniPath |
| NR3C1 | STAT5A | 27898060 8878484 9528750 | stimulant | N/A | OmniPath |
| STAT5A | STAT5B | 10358045 27898060 9398404 9528750 | N/A | N/A | OmniPath |
| IL2RG | STAT5A | 10582086 11418623 27898060 | stimulant | N/A | OmniPath |
| MPL | STAT5A | 10582086 27898060 | stimulant | N/A | OmniPath |
| CTLA4 | STAT5A | 16476059 25241761 27898060 | N/A | N/A | OmniPath |
| IL15RA | STAT5A | 10582086 27898060 | stimulant | N/A | OmniPath |
| IL2RB | STAT5A | 10602027 21516110 27898060 | stimulant | N/A | OmniPath |
| IL9R | STAT5A | 10582086 27898060 | stimulant | N/A | OmniPath |
| STAT5A | FOXP3 | 18270368 27898060 | stimulant | N/A | OmniPath |
| CISH | STAT5A | 11713228 27898060 | inhibition,stimulant | N/A | OmniPath |
| CRLF2 | STAT5A | 10582086 27898060 | stimulant | N/A | OmniPath |
| THRB | STAT5A | 10976919 27898060 | stimulant | N/A | OmniPath |
| DUSP3 | STAT5A | 17785772 27898060 | N/A | N/A | OmniPath |
| ACP1 | STAT5A | 14637146 27898060 | N/A | N/A | OmniPath |
