Gene Information gene info

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GENE：RNF31

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RNF31
FullNmae ring finger protein 31
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16031
EnsembleID ENSG00000092098
Uniprot Q96EP0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RNF31 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RNF31 necroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
RNF31 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RNF31 GO:0000209,GO:0004842,GO:0005515,GO:0005829,GO:0008270,GO:0009898,GO:0023035,GO:0031625,GO:0035631,GO:0036435,GO:0042742,GO:0042802,GO:0043123,GO:0043130,GO:0050852,GO:0051092,GO:0060546,GO:0061630,GO:0061630,GO:0070530,GO:0071797,GO:0071797,GO:0097039,GO:0097039,GO:1903955,GO:1904417,GO:1990450

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RNF31 hsa:55072 path:hsa04217 Necroptosis - Homo sapiens (human)
RNF31 hsa:55072 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
RNF31 hsa:55072 path:hsa05131 Shigellosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RBCK1 RNF31 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845 26192618 interaction type N/A ACSN
RNF31 SHARPIN 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845 26192618 interaction type N/A ACSN
RNF31 IKBKG 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845 26192618 interaction type N/A ACSN
RNF31 RBCK1 19136968 23180781 ubiquitination reaction,physical association anti tag coimmunoprecipitation,enzymatic study InnateDB
AZI2 RNF31 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRAF1 RNF31 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
RNF31 SMAD3 21988832 23180781 physical association anti tag coimmunoprecipitation InnateDB
RNF31 VCP 23180781 24461064 physical association anti tag coimmunoprecipitation InnateDB
RNF31 CYLD 23180781 24461064 physical association anti tag coimmunoprecipitation InnateDB
RNF31 OTULIN 23180781 24461064 physical association anti tag coimmunoprecipitation InnateDB
TLE5 RNF31 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 RNF31 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 RNF31 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RNF31 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RNF31 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RNF31 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETV4 RNF31 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
RNF31 RBCK1 25361965 interaction type N/A PTMCode2
RBCK1 RNF31 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNRPC RNF31 25348397 N/A physical interaction ComPPI
VASN RNF31 25348397 N/A physical interaction ComPPI
KRTAP9-2 RNF31 25348397 N/A physical interaction ComPPI
NOS3 RNF31 21163940 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPATA2 RNF31 25348397 N/A physical interaction ComPPI
SOCS3 RNF31 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNFAIP3 RNF31 23032186 24234451 25348397 30561431 association anti tag coimmunoprecipitation,physical interaction,virotrap ComPPI,IntAct
TRAF6 RNF31 25348397 N/A physical interaction ComPPI
VCP RNF31 25348397 N/A physical interaction ComPPI
ATXN1 RNF31 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBE2D1 RNF31 25348397 N/A physical interaction ComPPI
PITX1 RNF31 25348397 N/A physical interaction ComPPI
PRKCA RNF31 25348397 N/A physical interaction ComPPI
SMAD3 RNF31 21988832 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
UBE2D2 RNF31 24234451 25348397 26789245 N/A cosedimentation in solution,molecular sieving,x-ray crystallography,physical interaction ComPPI,IntAct
UBE2L3 RNF31 25348397 N/A physical interaction ComPPI
UBB RNF31 25348397 N/A isothermal titration calorimetry,pull down,physical interaction ComPPI
UBC RNF31 25348397 N/A isothermal titration calorimetry,pull down,physical interaction,physical interaction ComPPI
RPS27A RNF31 25348397 N/A isothermal titration calorimetry,pull down,physical interaction ComPPI
UBA52 RNF31 25348397 N/A isothermal titration calorimetry,pull down,physical interaction ComPPI
NTRK1 RNF31 25348397 N/A physical interaction ComPPI
PRKCB RNF31 25348397 N/A physical interaction ComPPI
TNFRSF1A RNF31 25348397 N/A physical interaction ComPPI
PDLIM7 RNF31 25348397 N/A physical interaction ComPPI
VDAC1 RNF31 25348397 N/A physical interaction ComPPI
IRAK1 RNF31 25348397 N/A physical interaction ComPPI
TNF RNF31 23032186 23955153 24234451 25348397 30561431 association anti tag coimmunoprecipitation,pull down,physical interaction,virotrap ComPPI,IntAct
PPARD RNF31 25348397 N/A physical interaction ComPPI
RABGEF1 RNF31 25348397 N/A physical interaction ComPPI
TRAF1 RNF31 25348397 N/A physical interaction ComPPI
TRAF2 RNF31 25348397 N/A physical interaction ComPPI
NR0B2 RNF31 25348397 N/A physical interaction ComPPI
LMO2 RNF31 25348397 N/A physical interaction ComPPI
GFI1B RNF31 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
NR0B1 RNF31 19237537 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SEPTIN2 RNF31 25348397 N/A physical interaction ComPPI
WRNIP1 RNF31 25348397 N/A physical interaction ComPPI
AKAP8L RNF31 25348397 N/A physical interaction ComPPI
TLE5 RNF31 25348397 N/A physical interaction ComPPI
HDAC6 RNF31 25348397 N/A physical interaction ComPPI
PRIM1 RNF31 25348397 N/A physical interaction ComPPI
RIPK1 RNF31 25348397 N/A physical interaction ComPPI
RIPK2 RNF31 25348397 N/A physical interaction ComPPI
PRKN RNF31 25348397 N/A physical interaction ComPPI
SNTG2 RNF31 25348397 N/A physical interaction ComPPI
UBE2D3 RNF31 25348397 N/A physical interaction ComPPI
CD40 RNF31 25348397 N/A physical interaction ComPPI
TRIM25 RNF31 25348397 N/A physical interaction ComPPI
BIRC2 RNF31 23524849 24234451 25348397 30561431 association anti tag coimmunoprecipitation,physical interaction,virotrap ComPPI,IntAct
BIRC3 RNF31 23524849 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BCL10 RNF31 25348397 N/A physical interaction ComPPI
LTBR RNF31 25348397 N/A physical interaction ComPPI
ESR1 RNF31 25348397 N/A physical interaction ComPPI
KIF1A RNF31 25348397 N/A physical interaction ComPPI
TLR3 RNF31 25348397 N/A physical interaction ComPPI
ATXN7 RNF31 21078624 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
IRF7 RNF31 25348397 N/A physical interaction ComPPI
NOD2 RNF31 25348397 N/A physical interaction ComPPI
CARD11 RNF31 25348397 N/A physical interaction ComPPI
MALT1 RNF31 25348397 N/A physical interaction ComPPI
SHARPIN RNF31 21455180 21455181 22158122 23032186 23104095 23746843 24141947 24234451 24461064 24726327 25348397 26600301 26670046 27898060 30561431 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,virotrap ComPPI,IntAct,OmniPath
SAV1 RNF31 22570112 24234451 25348397 physical association two hybrid ComPPI,IntAct
RNF31 RBCK1 14525934 17006537 17069764 19136968 20005846 21455180 21455181 22430200 22791023 23032187 23708998 24141947 24234451 24461064 24726327 25348397 26577923 26670046 27898060 29997244 30561431 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,bioluminescence resonance energy transfer,experimental interaction detection,isothermal titration calorimetry,molecular sieving,nuclear magnetic resonance,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,in vitro,in vivo,luminescence based mammalian interactome mapping,virotrap ComPPI,HPRD,IntAct,OmniPath
RNF31 AZI2 25348397 N/A physical interaction ComPPI
RNF31 DDX58 25348397 N/A physical interaction ComPPI
RNF31 ATN1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
RNF31 IKBKG 21455180 21811235 23032186 24234451 25348397 30561431 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,virotrap ComPPI,IntAct
RNF31 NDUFA8 25348397 N/A physical interaction ComPPI
RNF31 CCDC14 25348397 N/A physical interaction ComPPI
RNF31 TSSC4 25348397 N/A physical interaction ComPPI
RNF31 CCDC24 25348397 N/A physical interaction ComPPI
RNF31 ENDOV 25348397 N/A physical interaction ComPPI
RNF31 ARHGEF10 25348397 N/A physical interaction ComPPI
RNF31 LIPF 25348397 N/A physical interaction ComPPI
RNF31 LDLRAD4 25348397 N/A physical interaction ComPPI
RNF31 CYLD 25348397 N/A physical interaction ComPPI
RNF31 KCTD7 25348397 N/A physical interaction ComPPI
RNF31 IQCN 25348397 N/A physical interaction ComPPI
RNF31 PRIM2 25348397 N/A physical interaction ComPPI
RNF31 GBP1 25348397 N/A physical interaction ComPPI
RNF31 ZNF785 25348397 N/A physical interaction ComPPI
RNF31 ACTBL2 25348397 N/A physical interaction ComPPI
RNF31 MAVS 25348397 N/A physical interaction ComPPI
OTULIN RNF31 25348397 N/A physical interaction ComPPI
FKBPL RNF31 25348397 N/A physical interaction ComPPI
RNF31 REEP5 24234451 30561431 association virotrap IntAct
RNF31 HNRNPCL2 24234451 30561431 association virotrap IntAct
RNF31 HM13 24234451 30561431 association virotrap IntAct
RNF31 GOLGA3 24234451 30561431 association virotrap IntAct
RNF31 GDI1 24234451 30561431 association virotrap IntAct
RNF31 DNAH8 24234451 30561431 association virotrap IntAct
RNF31 RTN3 24234451 30561431 association virotrap IntAct
RNF31 RNF31 24234451 30561431 association virotrap IntAct
RNF31 SPR 24234451 30561431 association virotrap IntAct
RNF31 TNIP1 24234451 30561431 association virotrap IntAct
RNF31 CD82 24234451 30561431 association virotrap IntAct
RNF31 CYLD 24461064 26670046 27898060 N/A N/A OmniPath
AZI2 RNF31 21903422 27898060 N/A N/A OmniPath

Visualization










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