Gene Information gene info

  1. Home

GENE：VDAC3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol VDAC3
FullNmae voltage dependent anion channel 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12674
EnsembleID ENSG00000078668
Uniprot Q9Y277

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
VDAC3 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
VDAC3 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
VDAC3 necroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
VDAC3 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
VDAC3 ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
VDAC3 GO:0000166,GO:0005515,GO:0005634,GO:0005739,GO:0005739,GO:0005741,GO:0007283,GO:0008308,GO:0008308,GO:0015288,GO:0015853,GO:0016020,GO:0046930,GO:0070062,GO:0098656,GO:0120317

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
VDAC3 hsa:7419 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa04216 Ferroptosis - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa04217 Necroptosis - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa04218 Cellular senescence - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa04613 Neutrophil extracellular trap formation - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa04979 Cholesterol metabolism - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa05010 Alzheimer disease - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa05012 Parkinson disease - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa05016 Huntington disease - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa05020 Prion disease - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa05161 Hepatitis B - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
VDAC3 hsa:7419 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 VDAC3 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 VDAC3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 VDAC3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 VDAC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA VDAC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF VDAC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 VDAC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 VDAC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 VDAC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 VDAC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A VDAC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000021D7C8 VDAC3 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
ATP5PO VDAC3 25348397 N/A physical interaction ComPPI
RPN1 VDAC3 25348397 N/A physical interaction ComPPI
STX12 VDAC3 25348397 N/A physical interaction ComPPI
ATP5F1B VDAC3 25348397 N/A physical interaction ComPPI
TOMM22 VDAC3 25348397 N/A physical interaction ComPPI
MAGEA6 VDAC3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ACTB VDAC3 15047060 24234451 25348397 physical association molecular sieving ComPPI,IntAct
COX5A VDAC3 25348397 N/A physical interaction ComPPI
SF3B4 VDAC3 25348397 N/A physical interaction ComPPI
JAGN1 VDAC3 25348397 N/A physical interaction ComPPI
SLC38A1 VDAC3 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
DUSP23 VDAC3 25348397 N/A physical interaction ComPPI
CD4 VDAC3 25348397 N/A physical interaction ComPPI
HRAS VDAC3 25348397 N/A physical interaction ComPPI
SRC VDAC3 25348397 N/A physical interaction ComPPI
VAPA VDAC3 25348397 N/A physical interaction ComPPI
SERPINH1 VDAC3 25348397 N/A physical interaction ComPPI
UBC VDAC3 25348397 N/A physical interaction ComPPI
UBA52 VDAC3 25348397 N/A physical interaction ComPPI
NTRK1 VDAC3 25348397 N/A physical interaction ComPPI
PHB VDAC3 25348397 N/A physical interaction ComPPI
LAMTOR3 VDAC3 25348397 N/A physical interaction ComPPI
APOE VDAC3 25348397 N/A physical interaction ComPPI
VDAC1 VDAC3 24234451 25348397 29128334 30021884 association,physical association cross-linking study,physical interaction ComPPI,IntAct
RAP2A VDAC3 25348397 N/A physical interaction ComPPI
CLTC VDAC3 25348397 N/A physical interaction ComPPI
ABCE1 VDAC3 25348397 N/A physical interaction ComPPI
VDAC2 VDAC3 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
RPLP0 VDAC3 25348397 N/A physical interaction ComPPI
ATP1A1 VDAC3 25348397 N/A physical interaction ComPPI
SCP2 VDAC3 25348397 N/A physical interaction ComPPI
BCAP31 VDAC3 25348397 N/A physical interaction ComPPI
VAPB VDAC3 25348397 N/A physical interaction ComPPI
HTT VDAC3 17500595 24234451 25348397 association pull down ComPPI,IntAct
PHB2 VDAC3 25348397 N/A physical interaction ComPPI
RNF2 VDAC3 25348397 N/A physical interaction ComPPI
SF1 VDAC3 25348397 N/A physical interaction ComPPI
STX7 VDAC3 25348397 N/A physical interaction ComPPI
SSR3 VDAC3 25348397 N/A physical interaction ComPPI
PRKN VDAC3 25348397 N/A physical interaction ComPPI
PQBP1 VDAC3 25348397 N/A physical interaction ComPPI
IMMT VDAC3 25348397 N/A physical interaction ComPPI
CASP4 VDAC3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SSR1 VDAC3 25348397 N/A physical interaction ComPPI
ATP6V1A VDAC3 25348397 N/A physical interaction ComPPI
EIF4A1 VDAC3 25348397 N/A physical interaction ComPPI
IKBKE VDAC3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
FAF2 VDAC3 25348397 N/A physical interaction ComPPI
PPIF VDAC3 25348397 N/A physical interaction ComPPI
ATF2 VDAC3 22304920 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PIN4 VDAC3 25348397 N/A physical interaction ComPPI
RRP1B VDAC3 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
LYPD3 VDAC3 25348397 N/A physical interaction ComPPI
SARNP VDAC3 25348397 N/A physical interaction ComPPI
TOMM40 VDAC3 25348397 N/A physical interaction ComPPI
STOM VDAC3 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
ATP5F1C VDAC3 25348397 N/A physical interaction ComPPI
ATP5F1A VDAC3 25348397 N/A physical interaction ComPPI
ATP6V0D1 VDAC3 25348397 N/A physical interaction ComPPI
DDX24 VDAC3 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SLC25A3 VDAC3 25348397 N/A physical interaction ComPPI
TKT VDAC3 25348397 N/A physical interaction ComPPI
COX4I1 VDAC3 25348397 N/A physical interaction ComPPI
CYC1 VDAC3 25348397 N/A physical interaction ComPPI
SLC25A11 VDAC3 25348397 N/A physical interaction ComPPI
ILVBL VDAC3 25348397 N/A physical interaction ComPPI
ADGRE5 VDAC3 25348397 N/A physical interaction ComPPI
TMEM256 VDAC3 25348397 N/A physical interaction ComPPI
VDAC3 MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VDAC3 SUGP1 25348397 N/A physical interaction ComPPI
VDAC3 CDV3 25348397 N/A physical interaction ComPPI
VDAC3 RBM27 25348397 N/A physical interaction ComPPI
VDAC3 THY1 25348397 N/A physical interaction ComPPI
VDAC3 SCO2 25348397 N/A physical interaction ComPPI
VDAC3 SRPRB 25348397 N/A physical interaction ComPPI
VDAC3 ATP6V1H 25348397 N/A physical interaction ComPPI
VDAC3 ABCC1 25348397 N/A physical interaction ComPPI
VDAC3 NDUFA7 25348397 N/A physical interaction ComPPI
VDAC3 YME1L1 25348397 N/A physical interaction ComPPI
VDAC3 ACAA1 25348397 N/A physical interaction ComPPI
VDAC3 SBDS 25348397 N/A physical interaction ComPPI
VDAC3 FBXO6 25348397 N/A physical interaction ComPPI
VDAC3 OBSL1 25348397 N/A physical interaction ComPPI
VDAC3 RIC3 25348397 N/A physical interaction ComPPI
VDAC3 ATP5F1D 25348397 N/A physical interaction ComPPI
VDAC3 ATP5PD 25348397 N/A physical interaction ComPPI
VDAC3 ATP5ME 25348397 N/A physical interaction ComPPI
VDAC3 CISD1 25348397 N/A physical interaction ComPPI
VDAC3 CISD2 25348397 N/A physical interaction ComPPI
VDAC3 DDOST 25348397 N/A physical interaction ComPPI
VDAC3 MAGT1 25348397 N/A physical interaction ComPPI
VDAC3 NDUFA9 25348397 N/A physical interaction ComPPI
VDAC3 NDUFB7 25348397 N/A physical interaction ComPPI
VDAC3 NDUFB8 25348397 N/A physical interaction ComPPI
VDAC3 NDUFS4 25348397 N/A physical interaction ComPPI
VDAC3 NDUFS8 25348397 N/A physical interaction ComPPI
VDAC3 SGPL1 25348397 N/A physical interaction ComPPI
VDAC3 TECR 25348397 N/A physical interaction ComPPI
VDAC3 TSPO 25348397 N/A physical interaction ComPPI
VDAC3 ABCC3 25348397 N/A physical interaction ComPPI
VDAC3 ATP1B3 25348397 N/A physical interaction ComPPI
VDAC3 ATP5PB 25348397 N/A physical interaction ComPPI
VDAC3 MTCH1 25348397 N/A physical interaction ComPPI
VDAC3 MTCH2 25348397 N/A physical interaction ComPPI
VDAC3 MT-CO2 25348397 N/A physical interaction ComPPI
VDAC3 RPLP0P6 25348397 N/A physical interaction ComPPI
VDAC3 SDHB 25348397 N/A physical interaction ComPPI
VDAC3 TMX1 25348397 N/A physical interaction ComPPI
VDAC3 UBXN8 25348397 N/A physical interaction ComPPI
VDAC3 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VDAC3 ERICH5 25348397 N/A physical interaction ComPPI
VDAC3 FAM8A1 25348397 N/A physical interaction ComPPI
VDAC3 SPATA19 25348397 N/A physical interaction ComPPI
VDAC3 TPTE 25348397 N/A physical interaction ComPPI
VDAC3 COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
VDAC3 SOAT1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
VDAC3 DHRS2 15047060 24234451 25348397 physical association molecular sieving ComPPI,IntAct
VDAC3 GSTK1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
VDAC3 SERINC3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
VDAC3 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
VDAC3 ACAD9 23260140 24234451 25348397 association blue native page ComPPI,IntAct
VDAC3 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
MRPL53 VDAC3 25348397 N/A physical interaction ComPPI
VDAC3 RIF1 24234451 30021884 physical association cross-linking study IntAct
VDAC3 ZNF365 24234451 30021884 physical association cross-linking study IntAct
ZNF227 VDAC3 24234451 30021884 physical association cross-linking study IntAct
VDAC3 HIRIP3 24234451 30021884 physical association cross-linking study IntAct

Source Target Pmid Interactiontype Methods Database
URS00009C4D00 VDAC3 27087310 direct interaction,inhibition N/A NPInter

Visualization










  Return