Gene Information gene info

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GENE：SPATA2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SPATA2
FullNmae spermatogenesis associated 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14681
EnsembleID ENSG00000158480
Uniprot Q9UM82

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SPATA2 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SPATA2 necroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SPATA2 GO:0001650,GO:0005515,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0007283,GO:0010803,GO:0010803,GO:0030159,GO:0044877,GO:0050727,GO:0060544,GO:0060544,GO:0070266,GO:0070536,GO:0070536,GO:0072520,GO:1990108,GO:1990108,GO:1990381

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SPATA2 hsa:9825 path:hsa04217 Necroptosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP SPATA2 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 SPATA2 20034404 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 SPATA2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SPATA2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA SPATA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SPATA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SPATA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SPATA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SPATA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SPATA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SPATA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CREB1 SPATA2 N/A trascriptional regulation,stimulation inferred by curator TFlink
NFIC SPATA2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB SPATA2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00002FC5B0 SPATA2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000A07C1 SPATA2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000DDD35 SPATA2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000292B1 SPATA2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 SPATA2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002E628F SPATA2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 SPATA2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003808EC SPATA2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002367FA SPATA2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00006097A6 SPATA2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000BE495 SPATA2 20371350 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000010BD8D SPATA2 20371350 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000032D69B SPATA2 20371350 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002E92A8 SPATA2 20371350 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000427B68 SPATA2 20371350 21572407 22012620 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB SPATA2 20371350 21572407 22012620 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000202460 SPATA2 20371350 21572407 22012620 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 SPATA2 22473208 23446348 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002CAE0C SPATA2 21572407 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000266339 SPATA2 21572407 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000029D793 SPATA2 21572407 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001938D9 SPATA2 21572407 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004F24A9 SPATA2 21572407 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007A060 SPATA2 21572407 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 SPATA2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 SPATA2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002F3336 SPATA2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 SPATA2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00006DE17B SPATA2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 SPATA2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002B2B5C SPATA2 23313552 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000060AABB SPATA2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003CC709 SPATA2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000021D7C8 SPATA2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000033B548 SPATA2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000085F64 SPATA2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075B0F6 SPATA2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000419B5A SPATA2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000CC005 SPATA2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000036B845 SPATA2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075BDA4 SPATA2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000049FAE8 SPATA2 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000039E1E1 SPATA2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C770D SPATA2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000346991 SPATA2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000041E949 SPATA2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002152A8 SPATA2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000308E4D SPATA2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075A760 SPATA2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002FF522 SPATA2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000475586 SPATA2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000585553 SPATA2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000039A25B SPATA2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000070B1D SPATA2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SPATA2 GNAL 25361965 interaction type N/A PTMCode2
GNAL SPATA2 25361965 interaction type N/A PTMCode2
SPATA2 CASK 25361965 interaction type N/A PTMCode2
CASK SPATA2 25361965 interaction type N/A PTMCode2
LIN7B SPATA2 25361965 interaction type N/A PTMCode2
SPATA2 LIN7B 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TBC1D22B SPATA2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LENG1 SPATA2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GOLGA2 SPATA2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GPANK1 SPATA2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPATA2 LZTS2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPATA2 DUT 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SPATA2 TRAF2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SPATA2 CEP72 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SPATA2 PTPN6 11160222 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
SPATA2 CYLD 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPATA2 GNAL 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPATA2 PFDN4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPATA2 CASK 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPATA2 SSNA1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPATA2 PFDN6 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPATA2 BABAM1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPATA2 UIMC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPATA2 LIN7C 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPATA2 ELAVL1 25348397 N/A physical interaction ComPPI
SPATA2 APP 25348397 N/A physical interaction ComPPI
SPATA2 TRIM27 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPATA2 MAD1L1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPATA2 FGL2 25348397 N/A physical interaction ComPPI
SPATA2 CEP192 25348397 N/A physical interaction ComPPI
SPATA2 CNTROB 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SPATA2 CEP128 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SPATA2 CEP135 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SPATA2 CNTRL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SPATA2 ODF2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SPATA2 XPO1 25348397 N/A physical interaction ComPPI
SPATA2 RNF31 25348397 N/A physical interaction ComPPI
SPATA2 TNF 25348397 N/A physical interaction ComPPI
SPATA2 SHARPIN 25348397 N/A physical interaction ComPPI
SPATA2 PPP1CA 19389623 24234451 25348397 N/A pull down ComPPI,IntAct
SPATA2 TNIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPATA2 C2CD6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPATA2 ZNF835 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPATA2 CCDC102B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPATA2 KAT5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPATA2 ATP6V1H 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPATA2 EFHC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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