Gene Information gene info

GENE:ACADM

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ACADM
FullNmae acyl-CoA dehydrogenase medium chain
LocusType gene with protein product
Status Approved
HGNC_id HGNC:89
EnsembleID ENSG00000117054
Uniprot P11310

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ACADM mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ACADM GO:0001889,GO:0003995,GO:0003995,GO:0005634,GO:0005737,GO:0005739,GO:0005739,GO:0005759,GO:0005759,GO:0005978,GO:0006111,GO:0006635,GO:0009409,GO:0009791,GO:0019254,GO:0030424,GO:0031966,GO:0033539,GO:0033539,GO:0042594,GO:0042802,GO:0045329,GO:0050660,GO:0051791,GO:0051793,GO:0051793,GO:0055007,GO:0070991,GO:0070991

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ACADM hsa:34 path:hsa00071 Fatty acid degradation - Homo sapiens (human)
ACADM hsa:34 path:hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human)
ACADM hsa:34 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ACADM hsa:34 path:hsa01212 Fatty acid metabolism - Homo sapiens (human)
ACADM hsa:34 path:hsa03320 PPAR signaling pathway - Homo sapiens (human)
ACADM hsa:34 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR ACADM 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ACADM 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ACADM 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC ACADM 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ACADM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ACADM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ACADM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ACADM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ACADM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ACADM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ACADM 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 ACADM 17942906 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS000003ABC4 ACADM 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
ETFB ACADM 25361965 interaction type N/A PTMCode2
ACADM ETFB 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
USP20 ACADM 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPN1 ACADM 25348397 N/A physical interaction ComPPI
LDHB ACADM 25348397 N/A physical interaction ComPPI
LDHA ACADM 25348397 N/A physical interaction ComPPI
PPP2R1A ACADM 25348397 N/A physical interaction ComPPI
CALM1 ACADM 25348397 N/A physical interaction ComPPI
KEAP1 ACADM 25348397 N/A physical interaction ComPPI
JUN ACADM 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
CUL3 ACADM 25348397 N/A physical interaction ComPPI
CTSD ACADM 25348397 N/A physical interaction ComPPI
NTRK1 ACADM 25348397 N/A physical interaction ComPPI
CANX ACADM 25348397 N/A physical interaction ComPPI
HSP90B1 ACADM 25348397 N/A physical interaction ComPPI
VDAC1 ACADM 25348397 N/A physical interaction ComPPI
ANG ACADM 24234451 25348397 28777577 association anti bait coimmunoprecipitation ComPPI,IntAct
RAB2A ACADM 25348397 N/A physical interaction ComPPI
VDAC2 ACADM 25348397 N/A physical interaction ComPPI
ATP1A1 ACADM 25348397 N/A physical interaction ComPPI
STRAP ACADM 25348397 N/A physical interaction ComPPI
UQCRC2 ACADM 25348397 N/A physical interaction ComPPI
IDH3A ACADM 25348397 N/A physical interaction ComPPI
CAND1 ACADM 25348397 N/A physical interaction ComPPI
SUCLG2 ACADM 25348397 N/A physical interaction ComPPI
SUCLA2 ACADM 25348397 N/A physical interaction ComPPI
PDK1 ACADM 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CLPP ACADM 24234451 25348397 26058080 association proximity-dependent biotin identification ComPPI,IntAct
ARF4 ACADM 25348397 N/A physical interaction ComPPI
PPP2R1B ACADM 25348397 N/A physical interaction ComPPI
PRKCSH ACADM 25348397 N/A physical interaction ComPPI
SEC63 ACADM 25348397 N/A physical interaction ComPPI
ATP6V1A ACADM 25348397 N/A physical interaction ComPPI
DNAJA1 ACADM 25348397 N/A physical interaction ComPPI
FAF2 ACADM 25348397 N/A physical interaction ComPPI
ACADM SUMO4 14525934 16236267 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ACADM USP50 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACADM HDAC1 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACADM AASS 25348397 N/A physical interaction ComPPI
ACADM AHSA1 25348397 N/A physical interaction ComPPI
ACADM ARF1 25348397 N/A physical interaction ComPPI
ACADM ARF5 25348397 N/A physical interaction ComPPI
ACADM ATP9A 25348397 N/A physical interaction ComPPI
ACADM CCT6B 25348397 N/A physical interaction ComPPI
ACADM GALE 25348397 N/A physical interaction ComPPI
ACADM NFS1 25348397 N/A physical interaction ComPPI
ACADM SLC25A3 25348397 N/A physical interaction ComPPI
ACADM TECR 25348397 N/A physical interaction ComPPI
ACADM ATP5F1C 25348397 N/A physical interaction ComPPI
ACADM DDOST 25348397 N/A physical interaction ComPPI
ACADM DDX39B 25348397 N/A physical interaction ComPPI
ACADM ETFA 25348397 N/A physical interaction ComPPI
ACADM GFPT1 25348397 N/A physical interaction ComPPI
ACADM GFPT2 25348397 N/A physical interaction ComPPI
ACADM HIBCH 25348397 N/A physical interaction ComPPI
ACADM PSMC2 25348397 N/A physical interaction ComPPI
ACADM GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ACADM HSPD1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MGST3 ACADM 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRMT61B ACADM 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ACADM ACADM 14525934 24234451 3597357 8823176 N/A experimental interaction detection,molecular sieving HPRD,IntAct
PNKD ACADM 24234451 30021884 physical association cross-linking study IntAct

Visualization