GENE:DECR1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | DECR1 |
| FullNmae | 2,4-dienoyl-CoA reductase 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:2753 |
| EnsembleID | ENSG00000104325 |
| Uniprot | Q16698 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| DECR1 | mpt | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| DECR1 | GO:0005634,GO:0005654,GO:0005739,GO:0005739,GO:0005739,GO:0005759,GO:0005829,GO:0006635,GO:0006635,GO:0008670,GO:0008670,GO:0042802,GO:0070402,GO:0120162,GO:1902494 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | DECR1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | DECR1 | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | DECR1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | DECR1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | DECR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | DECR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | DECR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | DECR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TFAP2A | DECR1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00001EFEC1 | DECR1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000028DE3F | DECR1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | DECR1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008F0CF | DECR1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AAA0 | DECR1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000050CCE0 | DECR1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EFBE3 | DECR1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004214BB | DECR1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B0B46 | DECR1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F6E49 | DECR1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | DECR1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | DECR1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | DECR1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | DECR1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | DECR1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| EXOSC5 | DECR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CHMP2A | DECR1 | 25348397 | N/A | physical interaction | ComPPI |
| NPM1 | DECR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CCDC22 | DECR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NF2 | DECR1 | 25348397 | N/A | physical interaction | ComPPI |
| RPL10 | DECR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HGS | DECR1 | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | DECR1 | 25348397 | N/A | physical interaction | ComPPI |
| MSH6 | DECR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GEMIN5 | DECR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| JAK3 | DECR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| VCAM1 | DECR1 | 22623428 24234451 25348397 | association | cross-linking study,physical interaction | ComPPI,IntAct |
| ITGA4 | DECR1 | 25348397 | N/A | physical interaction | ComPPI |
| CREB3 | DECR1 | 25348397 | N/A | physical interaction | ComPPI |
| BAIAP2 | DECR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NOP56 | DECR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ECSIT | DECR1 | 25348397 | N/A | physical interaction | ComPPI |
| ESR1 | DECR1 | 21182205 24234451 25348397 | association | affinity chromatography technology,physical interaction | ComPPI,IntAct |
| SHMT2 | DECR1 | 25348397 | N/A | physical interaction | ComPPI |
| KIF11 | DECR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| LCOR | DECR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HSD17B4 | DECR1 | 25348397 | N/A | physical interaction | ComPPI |
| AK1 | DECR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| FN1 | DECR1 | 25348397 | N/A | physical interaction | ComPPI |
| APP | DECR1 | 25348397 | N/A | physical interaction | ComPPI |
| BCAR1 | DECR1 | 24234451 25348397 28007913 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| NXF1 | DECR1 | 25348397 | N/A | physical interaction | ComPPI |
| PTTG1 | DECR1 | 20360068 24234451 25348397 | physical association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| PTTG2 | DECR1 | 25348397 | N/A | physical interaction | ComPPI |
| DECR1 | NDUFA10 | 25348397 | N/A | physical interaction | ComPPI |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009B8608 | DECR1 | 27087310 | direct interaction,inhibition | N/A | NPInter |
