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GENE：F3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol F3
FullNmae coagulation factor III, tissue factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3541
EnsembleID ENSG00000117525
Uniprot P13726

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
F3 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
F3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
F3 GO:0001938,GO:0002020,GO:0002541,GO:0002543,GO:0004252,GO:0004896,GO:0005515,GO:0005543,GO:0005615,GO:0005886,GO:0006919,GO:0007596,GO:0009897,GO:0009986,GO:0009986,GO:0010628,GO:0010641,GO:0016020,GO:0016485,GO:0019221,GO:0030335,GO:0032757,GO:0045766,GO:0050927,GO:0051897,GO:0062023,GO:1905286

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
F3 hsa:2152 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)
F3 hsa:2152 path:hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR F3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
EGR1 F3 10707957 18971253 8576248 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
GATA1 F3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 F3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
RELA F3 11057875 11157486 18226221 19167713 9867853 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SP1 F3 10707957 8576248 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
SMARCA4 F3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA F3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF F3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 F3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS F3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A F3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 F3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 F3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
JUN F3 11057875 trascriptional regulation,stimulation inferred by curator TFlink
JUND F3 11057875 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 F3 11057875 11157486 19167713 9867853 trascriptional regulation,stimulation inferred by curator TFlink
REL F3 11057875 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 F3 10707957 8576248 trascriptional regulation,stimulation inferred by curator TFlink
CEBPB F3 N/A trascriptional regulation,stimulation inferred by curator TFlink
CEBPD F3 N/A trascriptional regulation,stimulation inferred by curator TFlink
CREB1 F3 N/A trascriptional regulation,stimulation inferred by curator TFlink
E2F4 F3 N/A trascriptional regulation,stimulation inferred by curator TFlink
HIF1A F3 N/A trascriptional regulation,stimulation inferred by curator TFlink
MYB F3 N/A trascriptional regulation,stimulation inferred by curator TFlink
NFIC F3 N/A trascriptional regulation,stimulation inferred by curator TFlink
SP3 F3 N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A F3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 F3 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00002C0FCB F3 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000DDD35 F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS000003ABC4 F3 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000021202F F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000033EBB8 F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075B0F6 F3 20371350 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000037D7E5 F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003883FE F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000184017 F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000A057E F3 20371350 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000035CC3E F3 20371350 21572407 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000025EABA F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000006F90B F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005606AA F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000B7E30 F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000042E1F F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000600E6 F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000298BA3 F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002B3783 F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002075FA F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000039E1E1 F3 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000237AF9 F3 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAPK14 F3 22135298 phosphorylation N/A PhosphoSite
PRKCA F3 22135298 phosphorylation N/A PhosphoSite
F3 F10 25361965 interaction type N/A PTMCode2
F10 F3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
STX12 F3 25348397 N/A physical interaction ComPPI
UBE2D1 F3 25348397 N/A physical interaction ComPPI
HPCAL4 F3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2D4 F3 25348397 N/A physical interaction ComPPI
UBE2D2 F3 25348397 N/A physical interaction ComPPI
FLNA F3 14525934 25348397 27898060 9490735 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
PLG F3 14525934 25348397 9490681 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
F10 F3 14525934 25348397 8702971 N/A experimental interaction detection,in vitro ComPPI,HPRD
F2RL1 F3 16959886 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
P4HB F3 16959886 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
F7 F3 12787023 14525934 15522303 15664864 24234451 25241761 25348397 8598903 8940045 9414278 9925787 physical association experimental interaction detection,x-ray crystallography,physical interaction,enzyme linked immunosorbent assay,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
UBE2D3 F3 25348397 N/A physical interaction ComPPI
DAD1 F3 25348397 N/A physical interaction ComPPI
ELAVL1 F3 25348397 N/A physical interaction ComPPI
PTPA F3 25348397 N/A physical interaction ComPPI
RAB13 F3 25348397 N/A physical interaction ComPPI
LPA F3 25348397 N/A physical interaction ComPPI
FANCB F3 11307801 11601848 14525934 25348397 27898060 8609606 9480775 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
F3 TM9SF4 25348397 N/A physical interaction ComPPI
PRKCA F3 12920028 15039423 18297283 20076769 21310953 23195225 27898060 stimulant N/A OmniPath
MAPK14 F3 15098027 23195225 27898060 inhibition N/A OmniPath
BLK F3 12920028 15039423 27898060 N/A N/A OmniPath

Visualization










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