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GENE：HIF1A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HIF1A
FullNmae hypoxia inducible factor 1 subunit alpha
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4910
EnsembleID ENSG00000100644
Uniprot Q16665

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HIF1A mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HIF1A mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HIF1A ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HIF1A autophagy 33455530 Proteomics and knockdown experiments further revealed HIF1A-BNIP3-ATG7 axis mediated the increase in autophagy flux, in which HMOX1 and SLC2A1 were also involved. retulator signature
HIF1A autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
HIF1A apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HIF1A apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
HIF1A GO:0000302,GO:0000785,GO:0000785,GO:0000791,GO:0000977,GO:0000977,GO:0000978,GO:0000981,GO:0000981,GO:0000981,GO:0000987,GO:0001216,GO:0001217,GO:0001223,GO:0001228,GO:0001228,GO:0001525,GO:0001666,GO:0001666,GO:0001678,GO:0001755,GO:0001837,GO:0001892,GO:0001922,GO:0001938,GO:0001947,GO:0002039,GO:0002039,GO:0002039,GO:0002052,GO:0002062,GO:0002071,GO:0002248,GO:0003151,GO:0003208,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0006089,GO:0006110,GO:0006355,GO:0006357,GO:0006879,GO:0007165,GO:0007405,GO:0007595,GO:0008542,GO:0010039,GO:0010468,GO:0010573,GO:0010575,GO:0010575,GO:0010628,GO:0010628,GO:0010629,GO:0010634,GO:0014850,GO:0016239,GO:0016604,GO:0016607,GO:0016922,GO:0019896,GO:0019899,GO:0019901,GO:0019904,GO:0021502,GO:0021987,GO:0030282,GO:0030502,GO:0030949,GO:0031514,GO:0031625,GO:0031625,GO:0031929,GO:0032007,GO:0032364,GO:0032722,GO:0032909,GO:0032963,GO:0032991,GO:0035162,GO:0035773,GO:0035774,GO:0042541,GO:0042826,GO:0043536,GO:0043565,GO:0043619,GO:0045648,GO:0045766,GO:0045766,GO:0045821,GO:0045893,GO:0045893,GO:0045926,GO:0045944,GO:0045944,GO:0045944,GO:0046716,GO:0046886,GO:0046982,GO:0048546,GO:0051000,GO:0051402,GO:0051541,GO:0051879,GO:0060574,GO:0061030,GO:0061072,GO:0061298,GO:0061419,GO:0061419,GO:0061629,GO:0070101,GO:0070244,GO:0070888,GO:0071347,GO:0071456,GO:0071456,GO:0071456,GO:0071542,GO:0090575,GO:0097152,GO:0097411,GO:0098586,GO:0140537,GO:1900017,GO:1902894,GO:1902895,GO:1902895,GO:1903377,GO:1903599,GO:1903715,GO:1904115,GO:2000273,GO:2000378,GO:2000434,GO:2001054

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HIF1A hsa:3091 path:hsa04066 HIF-1 signaling pathway - Homo sapiens (human)
HIF1A hsa:3091 path:hsa04137 Mitophagy - animal - Homo sapiens (human)
HIF1A hsa:3091 path:hsa04140 Autophagy - animal - Homo sapiens (human)
HIF1A hsa:3091 path:hsa04148 Efferocytosis - Homo sapiens (human)
HIF1A hsa:3091 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
HIF1A hsa:3091 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)
HIF1A hsa:3091 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
HIF1A hsa:3091 path:hsa05200 Pathways in cancer - Homo sapiens (human)
HIF1A hsa:3091 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
HIF1A hsa:3091 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
HIF1A hsa:3091 path:hsa05211 Renal cell carcinoma - Homo sapiens (human)
HIF1A hsa:3091 path:hsa05230 Central carbon metabolism in cancer - Homo sapiens (human)
HIF1A hsa:3091 path:hsa05231 Choline metabolism in cancer - Homo sapiens (human)
HIF1A hsa:3091 path:hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
HIF1A VEGFA 10804084 11486006 15674338 15735682 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21372296 21765015 22006996 22461508 22850421 22988108 23180781 23390297 24006507 25043024 25103413 25644713 25732824 25860662 26192618 interaction type,physical association anti tag coimmunoprecipitation,pull down,electrophoretic mobility supershift assay ACSN,InnateDB
HIF1A FOXP3 10804084 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824 26192618 interaction type N/A ACSN
SIRT3 HIF1A 21109197 22850421 26192618 interaction type N/A ACSN
JUND HIF1A 20535745 26192618 interaction type N/A ACSN
HIF1A CXCL12 10804084 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824 26192618 interaction type N/A ACSN
HIF1A CAV1 10804084 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824 26192618 interaction type N/A ACSN
HIF1A HK2 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type N/A ACSN
EIF4E HIF1A 10403805 11566883 12080085 12829734 13130303 15451019 15563472 16887934 1823643 26192618 7539918 8943284 9155017 9159130 9278421 9746763 9878069 interaction type N/A ACSN
HIF1A CXCR2 10804084 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 23869868 24006507 25043024 25103413 25732824 26192618 interaction type N/A ACSN
HIF1A BID 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type N/A ACSN
HIF1A PFKFB3 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type N/A ACSN
HIF1A PDK1 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type N/A ACSN
HIF1A LONP1 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type N/A ACSN
HIF1A COX4I2 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type N/A ACSN
HIF1A PFKFB4 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type N/A ACSN
HIF1A ALDOA 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type N/A ACSN
HIF1A PDK3 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type N/A ACSN
HIF1A NOS2 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type N/A ACSN
HIF1A FOXO3 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type N/A ACSN
HIF1A DDIT4 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type N/A ACSN
HIF1A EGLN1 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17353276 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 23180781 24006507 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type,physical association pull down ACSN,InnateDB
HIF1A EGLN3 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 23180781 24006507 24145445 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
HIF1A EGLN2 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 23180781 24006507 24145445 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
NFKB1 HIF1A 17272744 18393939 21725609 23178297 23572150 26192618 interaction type N/A ACSN
RPTOR HIF1A 12150925 12777372 15755954 15854902 16469695 16915281 17991864 19299511 19864431 19942859 20484410 22025673 22841746 23087689 26159692 26192618 interaction type N/A ACSN
CUL2 HIF1A 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
RACK1 HIF1A 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 HIF1A 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
VHL HIF1A 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
STAT3 HIF1A 10347215 10973499 12223527 14607900 14670306 15218058 15356132 15573129 16418395 18776941 18985005 19380816 20093776 20237412 20406969 20581311 21840487 23124025 23454751 23953057 24857661 26192618 27216177 28186502 7543512 interaction type N/A ACSN
OS9 HIF1A 12351678 15652751 15721254 26192618 interaction type N/A ACSN
HIF1AN HIF1A 11641274 12042299 12080085 12215170 22841746 26192618 interaction type N/A ACSN
SART1 HIF1A 18838541 26192618 interaction type N/A ACSN
HIF1A MICB 10804084 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824 26192618 interaction type N/A ACSN
HIF1A ADAM10 10804084 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824 26192618 interaction type N/A ACSN
HIF1A IL6 10804084 15749903 16110315 16127144 16243976 16413922 17485448 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824 26192618 9743347 interaction type N/A ACSN
MYC HIF1A 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027 26192618 interaction type N/A ACSN
IL4 HIF1A 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 26192618 2965306 9834059 interaction type N/A ACSN
IL13 HIF1A 12223527 12401408 14610620 14657224 15099563 18250477 18451175 20184663 21097505 26192618 26755705 9535722 interaction type N/A ACSN
IFNG HIF1A 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26192618 26755705 2965306 6425450 9834059 9864217 interaction type N/A ACSN
CSF2 HIF1A 10426994 11015446 11280761 11460167 11777960 11907067 12193690 12907458 14660645 15536084 16713974 17301840 18264787 20805416 21133840 21232017 21765015 22869907 24030977 24699077 24958845 26192618 interaction type N/A ACSN
HIF1A TNF 10754326 10804084 10952726 11875494 12907458 14660645 15465827 15644117 16110315 16127144 16878026 17404308 17485448 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 23390297 24006507 25043024 25103413 25732824 26192618 7594497 interaction type N/A ACSN
HIF1A MIF 10804084 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824 26192618 interaction type N/A ACSN
HIF1A AR 17011549 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A CUL2 17439941 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A RPTOR 17502379 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
HIF1A EP300 17502379 23180781 physical association anti tag coimmunoprecipitation InnateDB
EGLN3 HIF1A 17353276 23180781 physical association pull down InnateDB
HIF1A ENG 12228247 23180781 physical association electrophoretic mobility supershift assay InnateDB
HIF1A SP1 12228247 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A SMAD3 11486006 12228247 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
SMAD4 HIF1A 11486006 23180781 physical association electrophoretic mobility supershift assay InnateDB
HIF1A ARNT 11486006 16126907 17277313 23180781 physical association electrophoretic mobility supershift assay InnateDB
HIF1A ACE 19592460 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A EGR1 18506761 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A CHKA 18172309 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A EPO 15674338 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A CEACAM5 17657737 23180781 physical association anti tag coimmunoprecipitation InnateDB
NDRG2 HIF1A 18209490 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A STAT3 15735682 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A MUC3A 16823775 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A MVP 20175781 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A SERPINE1 15968405 23180781 physical association electrophoretic mobility supershift assay InnateDB
HIF1A PGK1 16126907 23180781 physical association electrophoretic mobility supershift assay InnateDB
HIF1A HIF3A 16126907 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A NAA10 18593917 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A CTNNB1 18593917 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A MDM2 17234751 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A HDAC1 17273746 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A HDAC3 17273746 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A SEPTIN9 19934318 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A CXCR4 17083723 20007689 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A KCNMB1 22114151 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A NR4A3 19720740 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A VASP 22320863 23180781 physical association electrophoretic mobility supershift assay InnateDB
HIF1A HIF1AN 23180781 24145445 physical association anti tag coimmunoprecipitation InnateDB
EGLN1 HIF1A 23180781 24145445 physical association anti tag coimmunoprecipitation InnateDB
HIF1A CNPY2 23180781 25589425 physical association anti tag coimmunoprecipitation InnateDB
HIF1A YY1 23180781 25644713 physical association anti tag coimmunoprecipitation InnateDB
ZFP36 HIF1A 23180781 25644713 physical association anti tag coimmunoprecipitation InnateDB
HIF1A VTCN1 23180781 25725157 physical association anti tag coimmunoprecipitation InnateDB
ARNTL HIF1A 23180781 25416956 physical association two hybrid InnateDB
HIF1A HILPDA 23180781 25889814 physical association anti tag coimmunoprecipitation InnateDB
HIF1A ANGPTL4 23180781 25889814 physical association anti tag coimmunoprecipitation InnateDB
HIF1A LEP 23180781 25889814 physical association anti tag coimmunoprecipitation InnateDB
NOTCH1 HIF1A 18722525 23331499 stimulation N/A SignaLink,SignaLink

Source Target Pmid Interactiontype Methods Database
AR HIF1A 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
EGR1 HIF1A 18506761 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
ESR1 HIF1A 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 HIF1A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 HIF1A 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC HIF1A 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 HIF1A 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 HIF1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HIF1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HIF1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 HIF1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HIF1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HIF1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HIF1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HIF1A 18971253 22012259 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 HIF1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ARNT HIF1A 14764593 trascriptional regulation,stimulation inferred by curator TFlink
BRCA1 HIF1A 16543242 trascriptional regulation,stimulation inferred by curator TFlink
FOXO4 HIF1A 12761217 20136501 trascriptional regulation,stimulation inferred by curator TFlink
HDAC7 HIF1A 20693714 22172637 trascriptional regulation,stimulation inferred by curator TFlink
HDAC9 HIF1A 20693714 22172637 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A HIF1A 14744852 trascriptional regulation,stimulation inferred by curator TFlink
HIF3A HIF1A 19755485 trascriptional regulation,stimulation inferred by curator TFlink
HIPK2 HIF1A 19046997 trascriptional regulation,stimulation inferred by curator TFlink
HSF2 HIF1A 21258402 trascriptional regulation,stimulation inferred by curator TFlink
HSF4 HIF1A 21258402 trascriptional regulation,stimulation inferred by curator TFlink
KLF5 HIF1A 23880760 trascriptional regulation,stimulation inferred by curator TFlink
LIMD1 HIF1A 22286099 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 HIF1A 18498249 trascriptional regulation,stimulation inferred by curator TFlink
NFKB2 HIF1A 19414801 trascriptional regulation,stimulation inferred by curator TFlink
RELA HIF1A 18498249 trascriptional regulation,stimulation inferred by curator TFlink
SIRT1 HIF1A 22245592 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 HIF1A 17597020 18644974 19265129 23991099 trascriptional regulation,stimulation inferred by curator TFlink
USF2 HIF1A 23991099 trascriptional regulation,stimulation inferred by curator TFlink
VHL HIF1A 11727931 11987242 19238077 trascriptional regulation,stimulation inferred by curator TFlink
YY1 HIF1A 20660740 trascriptional regulation,stimulation inferred by curator TFlink
ZFP36 HIF1A 19962963 trascriptional regulation,stimulation inferred by curator TFlink
ZNF823 HIF1A 19962963 trascriptional regulation,stimulation inferred by curator TFlink
SP1 HIF1A N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000008F0CF HIF1A 20308559 rna interference,inhibition western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000029EBD HIF1A 21557766 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000042E1F HIF1A 18632605 rna interference,inhibition western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00002B3783 HIF1A 20232316 rna interference,inhibition experimental interaction detection,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr miRSponge
URS00000F0F49 HIF1A 20972335 rna interference,inhibition array technology,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000037D7E5 HIF1A 20233879 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000042E1F HIF1A 18632605 22473208 23911400 25416803 mrna cleavage,inhibition western blot,northern blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000037D7E5 HIF1A 20233879 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00002B3783 HIF1A 20232316 22473208 25416803 26612965 26793992 mrna cleavage,inhibition experimental interaction detection,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000008F0CF HIF1A 20308559 25416803 mrna cleavage,inhibition western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000035CC3E HIF1A 20371350 21572407 22012620 25416803 26622381 27080303 mrna cleavage,inhibition nucleotide sequence identification,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00002075FA HIF1A 22473208 23911400 24252850 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00000F0F49 HIF1A 20972335 25416803 mrna cleavage,inhibition array technology,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000029EBD HIF1A 21557766 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000CBE63 HIF1A 20371350 25416803 25891797 mrna cleavage,inhibition nucleotide sequence identification,miRNA interference luciferase reporter assay TarBase
URS00000600E6 HIF1A 22473208 23622248 25416803 27325313 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,clash,miRNA interference luciferase reporter assay TarBase
URS0000324096 HIF1A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000055128B HIF1A 23618526 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS000052EA98 HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004214BB HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000045B99E HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000033EBB8 HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000166778 HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 HIF1A 22473208 22815788 25416803 26815014 mrna cleavage,inhibition array technology,experimental interaction detection,nucleotide sequence identification,quantitative reverse transcription pcr,immunocytochemistry,clip TarBase
URS000039E1E1 HIF1A 21572407 25416803 27325313 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000298BA3 HIF1A 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000A057E HIF1A 21572407 22012620 25416803 27220837 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00003808EC HIF1A 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000020CEC2 HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000016C318 HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000338542 HIF1A 25143000 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry TarBase
URS0000096022 HIF1A 24496460 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr TarBase
URS000009262D HIF1A 23726431 25416803 mrna cleavage,inhibition chromatin immunoprecipitation assay TarBase
URS0000215483 HIF1A 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002E177F HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000060B2B HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001FA076 HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000C36BD HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002198F3 HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000017DBB8 HIF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002AAD6B HIF1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB0E HIF1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002AA55A HIF1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A HIF1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B HIF1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000535FDD HIF1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA HIF1A 25416803 28069592 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS00001B341F HIF1A 25416803 26292288 mrna cleavage,inhibition western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000024DFCE HIF1A 25416803 27815672 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000055BBE5 HIF1A 25416803 25550463 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS00000254A6 HIF1A 25416803 26260688 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunocytochemistry,miRNA interference luciferase reporter assay TarBase
URS000021D7C8 HIF1A 25416803 27159677 mrna cleavage,inhibition experimental interaction detection,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000040780F HIF1A 25416803 27284341 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS00004F4657 HIF1A 25416803 26196183 mrna cleavage,inhibition chromatin immunoprecipitation assay,quantitative reverse transcription pcr TarBase
URS0000171525 HIF1A 25416803 26815014 mrna cleavage,inhibition experimental interaction detection,nucleotide sequence identification,quantitative reverse transcription pcr,immunocytochemistry TarBase
URS000007D64A HIF1A 25416803 26718330 mrna cleavage,inhibition western blot,immunohistochemistry TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA HIF1A 22135298 phosphorylation N/A PhosphoSite
CSNK1D HIF1A 22135298 phosphorylation N/A PhosphoSite
CDK1 HIF1A 22135298 phosphorylation N/A PhosphoSite
MAPK1 HIF1A 22135298 phosphorylation N/A PhosphoSite
CDK5 HIF1A 22135298 phosphorylation N/A PhosphoSite
ATM HIF1A 22135298 phosphorylation N/A PhosphoSite
PLK3 HIF1A 22135298 phosphorylation N/A PhosphoSite
EGLN3 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A EGLN3 25361965 interaction type N/A PTMCode2
MTA1 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A MTA1 25361965 interaction type N/A PTMCode2
NCOA1 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A NCOA1 25361965 interaction type N/A PTMCode2
STAT3 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A STAT3 25361965 interaction type N/A PTMCode2
HIF1AN HIF1A 25361965 interaction type N/A PTMCode2
HIF1A HIF1AN 25361965 interaction type N/A PTMCode2
KAT2B HIF1A 25361965 interaction type N/A PTMCode2
HIF1A KAT2B 25361965 interaction type N/A PTMCode2
UBXN7 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A UBXN7 25361965 interaction type N/A PTMCode2
TP53 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A TP53 25361965 interaction type N/A PTMCode2
ESRRA HIF1A 25361965 interaction type N/A PTMCode2
HIF1A ESRRA 25361965 interaction type N/A PTMCode2
ARNT2 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A ARNT2 25361965 interaction type N/A PTMCode2
HIF1A CTNNB1 25361965 interaction type N/A PTMCode2
CTNNB1 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A TSGA10 25361965 interaction type N/A PTMCode2
TSGA10 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A ARNT 25361965 interaction type N/A PTMCode2
ARNT HIF1A 25361965 interaction type N/A PTMCode2
HIF1A EGLN1 25361965 interaction type N/A PTMCode2
EGLN1 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A RWDD3 25361965 interaction type N/A PTMCode2
RWDD3 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A JUN 25361965 interaction type N/A PTMCode2
JUN HIF1A 25361965 interaction type N/A PTMCode2
HIF1A PGK1 25361965 interaction type N/A PTMCode2
PGK1 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A SUMO1 25361965 interaction type N/A PTMCode2
SUMO1 HIF1A 25361965 interaction type N/A PTMCode2
NOTCH1 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A NOTCH1 25361965 interaction type N/A PTMCode2
HDAC3 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A HDAC3 25361965 interaction type N/A PTMCode2
VHL HIF1A 25361965 interaction type N/A PTMCode2
HIF1A VHL 25361965 interaction type N/A PTMCode2
APEX1 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A APEX1 25361965 interaction type N/A PTMCode2
HSP90AA1 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A HSP90AA1 25361965 interaction type N/A PTMCode2
NDN HIF1A 25361965 interaction type N/A PTMCode2
HIF1A NDN 25361965 interaction type N/A PTMCode2
SAT2 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A SAT2 25361965 interaction type N/A PTMCode2
HDAC4 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A HDAC4 25361965 interaction type N/A PTMCode2
PSMC3 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A PSMC3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2I HIF1A 25348397 N/A physical interaction ComPPI
USP20 HIF1A 15776016 25348397 27898060 N/A physical interaction ComPPI,OmniPath
KPNA4 HIF1A 25348397 N/A physical interaction ComPPI
HSPA8 HIF1A 25348397 N/A physical interaction ComPPI
FBP1 HIF1A 24234451 25043030 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
RHOBTB3 HIF1A 25348397 N/A physical interaction ComPPI
SPRY2 HIF1A 25348397 N/A physical interaction ComPPI
LDHA HIF1A 25348397 N/A physical interaction ComPPI
PSMC3 HIF1A 25348397 N/A physical interaction ComPPI
SAT1 HIF1A 25348397 N/A physical interaction ComPPI
TRAF6 HIF1A 25348397 N/A physical interaction ComPPI
VCP HIF1A 18775313 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2D1 HIF1A 25348397 N/A physical interaction ComPPI
DCUN1D1 HIF1A 25348397 N/A physical interaction ComPPI
ZC3H12A HIF1A 25348397 N/A physical interaction ComPPI
HSP90AB1 HIF1A 18538669 24234451 25348397 N/A surface plasmon resonance,physical interaction,surface plasmon resonance array ComPPI,IntAct
PCGF2 HIF1A 21602890 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RACK1 HIF1A 25348397 N/A physical interaction ComPPI
VHLL HIF1A 14525934 14757845 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
CSNK1D HIF1A 25348397 N/A physical interaction ComPPI
EGLN3 HIF1A 14525934 15474027 15721254 16511565 17353276 24234451 25348397 26972000 hydroxylation reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
MAPK1 HIF1A 25348397 N/A physical interaction ComPPI
SP1 HIF1A 14525934 17024177 17418410 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,competition binding,in vivo ComPPI,HPRD,IntAct
SRC HIF1A 25348397 N/A physical interaction ComPPI
FBXW7 HIF1A 25348397 N/A physical interaction ComPPI
NOTCH1 HIF1A 18427106 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SHC1 HIF1A 25348397 N/A physical interaction ComPPI
PRKDC HIF1A 25348397 N/A physical interaction ComPPI
MAPK3 HIF1A 10551817 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
JUN HIF1A 11739718 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RB1 HIF1A 25348397 N/A physical interaction ComPPI
AR HIF1A 14525934 17426252 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
CREBBP HIF1A 10202154 11959977 14525934 16543236 17382325 21602890 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,fluorescence technology,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
RUNX2 HIF1A 25348397 N/A physical interaction ComPPI
SUMO1 HIF1A 20661221 24234451 24434214 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NCOA1 HIF1A 10594042 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EP300 HIF1A 11823643 11959990 12778114 14525934 15261140 17382325 18268343 18519678 19071119 19680224 20603618 23746844 24234451 24421387 25348397 26751287 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,fluorescence technology,pull down,physical interaction,competition binding,in vitro,in vivo ComPPI,HPRD,IntAct
SMAD3 HIF1A 24234451 25348397 28471448 colocalization,physical association anti bait coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
HIF1A VHL 10823831 10944113 11292862 11504942 12004076 12050673 14525934 15721254 16511565 17353276 18323857 21602890 24234451 25348397 25438054 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,far western blotting,filter binding,pull down,surface plasmon resonance,physical interaction,enzyme linked immunosorbent assay,in vitro,in vivo ComPPI,HPRD,IntAct
HIF1A NAA10 12464182 14525934 16288748 16511565 16638120 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
HIF1A PGK1 14525934 25348397 8089148 N/A experimental interaction detection,in vivo ComPPI,HPRD
HIF1A DAP3 10903152 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HIF1A PER1 11726537 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
HIF1A ARNTL 14525934 25348397 9576906 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
HIF1A PSMA7 11389899 14525934 18313384 24234451 25348397 27898060 physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
HIF1A COPS5 11707426 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
HIF1A EGLN2 11292861 11292862 14525934 15474027 16511565 17353276 24234451 25348397 hydroxylation reaction,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
HIF1A NCOA2 10594042 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
HIF1A HIF1AN 11641274 12446723 14525934 14734545 17003112 17382325 19071119 24234451 25348397 26751287 26752685 26972000 hydroxylation reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,x-ray crystallography,hydroxylation reaction,physical interaction,in vitro,in vivo,hydroxylase assay,decarboxylation assay,two hybrid ComPPI,HPRD,IntAct
HIF1A HIF3A 11734856 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
HIF1A ARNT2 14525934 25348397 8927054 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
HIF1A CDKN2A 11382768 25348397 27898060 N/A physical interaction,in vivo ComPPI,OmniPath
HIF1A NDN 14525934 15978586 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
HIF1A SSX4 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HIF1A NAA11 14525934 16638120 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
HIF1A CSNK2A1 14525934 17382325 24234451 25348397 phosphorylation reaction experimental interaction detection,protein kinase assay,in vitro ComPPI,HPRD,IntAct
HIF1A MAX 14525934 17418410 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
HIF1A EGLN1 14525934 15474027 15721254 16511565 17353276 20840591 24234451 25348397 hydroxylation reaction,enzymatic reaction,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,x-ray crystallography,physical interaction,enzymatic study,in vitro,in vivo ComPPI,HPRD,IntAct
HIF1A CITED2 12778114 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
HIF1A TSGA10 14525934 16777103 24234451 25348397 27898060 colocalization two hybrid,experimental interaction detection,imaging technique,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
HIF1A MTA1 14525934 16511565 16969516 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,imaging technique,in vivo ComPPI,HPRD,IntAct,OmniPath
HIF1A CTNNB1 14525934 17220880 24234451 24650032 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
HIF1A OS9 14525934 15721254 24234451 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
HIF1A STAT3 14525934 18985005 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
HIF1A NR4A1 14525934 18305400 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HIF1A RWDD3 17956732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
HIF1A HSP90AA1 14525934 18538669 24234451 25348397 9079689 N/A experimental interaction detection,surface plasmon resonance,physical interaction,in vitro,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
HIF1A MDM2 10640274 12606552 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
HIF1A ZNF197 25348397 N/A physical interaction ComPPI
HIF1A TP53 12124396 14525934 25348397 9537326 N/A experimental interaction detection,physical interaction ComPPI,HPRD
HIF1A HDAC1 14525934 16511565 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
HIF1A HDAC2 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
HIF1A HDAC3 25348397 N/A physical interaction ComPPI
HIF1A APEX1 10594042 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
HIF1A ARNT 14525934 19168635 20562859 20603618 20932347 21620138 24234451 24434214 25348397 9079689 9704006 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid ComPPI,HPRD,IntAct
HIF1A HSP90AA2P 25348397 N/A physical interaction ComPPI
HIF1A ELOC 12004076 12050673 17353276 24234451 25348397 physical association filter binding,surface plasmon resonance,physical interaction,enzyme linked immunosorbent assay,surface plasmon resonance array ComPPI,IntAct
HIF1A CUL2 18323857 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A HSPA4 14726529 15319539 16507982 16951198 19802386 19940151 21124777 23722539 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HIF1A BANP 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A HDAC4 19071119 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
HIF1A HDAC5 19071119 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
HIF1A HDAC6 25348397 N/A physical interaction ComPPI
HIF1A PARP1 25348397 N/A physical interaction ComPPI
HIF1A SMARCA2 25348397 N/A physical interaction ComPPI
HIF1A SMARCA4 25348397 N/A physical interaction ComPPI
HIF1A MYC 25348397 N/A physical interaction ComPPI
HIF1A RUVBL2 25348397 N/A physical interaction ComPPI
HIF1A MCM7 25348397 N/A physical interaction ComPPI
HIF1A MCM3 25348397 N/A physical interaction ComPPI
HIF1A COMMD1 25348397 N/A physical interaction ComPPI
HIF1A NSFL1C 25348397 N/A physical interaction ComPPI
HIF1A FAF2 18775313 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A FAF1 25348397 N/A physical interaction ComPPI
HIF1A UBXN7 18775313 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A UBXN1 25348397 N/A physical interaction ComPPI
HIF1A STUB1 25348397 N/A physical interaction ComPPI
HIF1A ELOB 12004076 12050673 17353276 24234451 25348397 physical association filter binding,isothermal titration calorimetry,surface plasmon resonance,x-ray crystallography,physical interaction,enzyme linked immunosorbent assay ComPPI,IntAct
HIF1A RAD23B 25348397 N/A physical interaction ComPPI
HIF1A KDM3A 25348397 N/A physical interaction ComPPI
HIF1A BCR 25348397 N/A physical interaction ComPPI
HIF1A DNAJB1 25348397 N/A physical interaction ComPPI
HIF1A USP19 25348397 N/A physical interaction ComPPI
HIF1A PTGES3 25348397 N/A physical interaction ComPPI
HIF1A HDAC7 25348397 N/A physical interaction ComPPI
HIF1A KAT2B 16543236 24234451 25348397 physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
HIF1A F12 25348397 N/A physical interaction ComPPI
HIF1A BHLHE41 22801492 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A BRCA1 25348397 N/A physical interaction ComPPI
HIF1A CAPN1 25348397 N/A physical interaction ComPPI
HIF1A LAMP2 19458911 23880665 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HIF1A BCL2 25348397 N/A physical interaction ComPPI
HIF1A CDKN2A 25348397 N/A physical interaction ComPPI
HIF1A ESR1 21182205 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
HIF1A RPTOR 25348397 N/A physical interaction ComPPI
HIF1A RELA 25348397 N/A physical interaction ComPPI
HIF1A EPAS1 25348397 N/A physical interaction ComPPI
HIF1A MAFG 18538669 24234451 25348397 colocalization,physical association two hybrid,surface plasmon resonance,physical interaction,fluorescence microscopy ComPPI,IntAct
HIF1A MAFK 18538669 24234451 25348397 N/A surface plasmon resonance,physical interaction ComPPI,IntAct
HIF1A RBX1 25348397 N/A physical interaction ComPPI
HIF1A HEXIM1 25348397 N/A physical interaction ComPPI
HIF1A SQSTM1 25348397 N/A physical interaction ComPPI
HIF1A TRIM28 25348397 N/A physical interaction ComPPI
HIF1A SIN3A 25348397 N/A physical interaction ComPPI
HIF1A SART3 25348397 N/A physical interaction ComPPI
HIF1A ATM 25348397 N/A physical interaction ComPPI
HIF1A SENP3 19680224 24234451 25348397 colocalization physical interaction,fluorescence microscopy ComPPI,IntAct
HIF1A FHL2 25348397 N/A physical interaction ComPPI
HIF1A PLD1 25348397 N/A physical interaction ComPPI
HIF1A WWOX 25348397 N/A physical interaction ComPPI
HIF1A WWTR1 25348397 N/A physical interaction ComPPI
HIF1A CDK8 23746844 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
HIF1A MED12 23746844 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
HIF1A MED13 23746844 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
HIF1A MED13L 23746844 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
HIF1A MED14 23746844 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
HIF1A MED15 23746844 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
HIF1A MED23 23746844 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
HIF1A EAF2 24234451 24421387 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A FDX1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A FN1 25348397 N/A physical interaction ComPPI
HIF1A PIAS1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A ZNF518A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A CEP350 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A NES 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A MID2 25348397 N/A physical interaction ComPPI
HIF1A PLEKHA5 25348397 N/A physical interaction ComPPI
HIF1A UACA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A NLN 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A NBEAL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A GKAP1 25348397 N/A physical interaction ComPPI
HIF1A UTP23 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A MICOS13 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A TCEANC2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A LYSMD2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A OTUD7B 25348397 N/A physical interaction ComPPI
HIF1A PLD2 25348397 N/A physical interaction ComPPI
HIF1A PSMD10 25348397 N/A physical interaction ComPPI
HIF1A ING1 25348397 N/A physical interaction ComPPI
HIF1A GPLD1 25348397 N/A physical interaction ComPPI
HIF1A MYH6 25348397 N/A physical interaction ComPPI
HIF1A MYH2 25348397 N/A physical interaction ComPPI
HIF1A MYH3 25348397 N/A physical interaction ComPPI
HIF1A ACTA1 25348397 N/A physical interaction ComPPI
HIF1A MYH4 25348397 N/A physical interaction ComPPI
HIF1A MYL1 25348397 N/A physical interaction ComPPI
HIF1A H2AX 25348397 N/A physical interaction ComPPI
HIF1A PSMA4 22801492 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A PTK6 25348397 N/A physical interaction ComPPI
HIF1A LRRK2 25348397 N/A physical interaction ComPPI
HIF1A FASN 25348397 N/A physical interaction ComPPI
HIF1A IKBKG 25348397 N/A physical interaction ComPPI
HIF1A IKBKB 25348397 N/A physical interaction ComPPI
HIF1A HSPA1L 25348397 N/A physical interaction ComPPI
HIF1A HNRNPL 25348397 N/A physical interaction ComPPI
HIF1A HNF4A 25348397 N/A physical interaction ComPPI
HIF1A UBC 19950214 24478626 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HIF1A SIRT1 25348397 N/A physical interaction ComPPI
HIF1A CEBPA 25348397 N/A physical interaction ComPPI
HIF1A TP73 25348397 N/A physical interaction ComPPI
HIF1A KDM4C 25348397 N/A physical interaction ComPPI
HIF1A CBFA2T3 25348397 N/A physical interaction ComPPI
HIF1A PFKFB4 25348397 N/A physical interaction ComPPI
HIF1A PFKFB3 25348397 N/A physical interaction ComPPI
HIF1A PDK1 25348397 N/A physical interaction ComPPI
HIF1A PFKM 25348397 N/A physical interaction ComPPI
HIF1A HK1 25348397 N/A physical interaction ComPPI
HIF1A NBN 25348397 N/A physical interaction ComPPI
HIF1A PRKACA 25348397 N/A physical interaction ComPPI
HIF1A CASR 25348397 N/A physical interaction ComPPI
HIF1A XRCC6 25348397 N/A physical interaction ComPPI
HIF1A XRCC5 25348397 N/A physical interaction ComPPI
HIF1A MIP 25348397 N/A physical interaction ComPPI
HIF1A ELAVL1 25348397 N/A physical interaction ComPPI
HIF1A PTBP1 25348397 N/A physical interaction ComPPI
HIF1A TUBA1A 25348397 N/A physical interaction ComPPI
HIF1A DNAI1 25348397 N/A physical interaction ComPPI
HIF1A ARRB1 21685944 24234451 25348397 27898060 colocalization,physical association cross-linking study,physical interaction,confocal microscopy ComPPI,IntAct,OmniPath
HIF1A FOXO3 18268343 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A ESRRA 18509053 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
HIF1A MUC1 22869720 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A XBP1 24234451 24670641 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
HIF1A YAP1 24234451 25348397 25438054 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1A SUMO3 19680224 24234451 25348397 physical association pull down ComPPI,IntAct
HIF1A PIAS4 20661221 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
HIF1A CBX4 24234451 24434214 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,chromatin immunoprecipitation assay ComPPI,IntAct
HIF1A USP8 24234451 24378640 25348397 physical association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
HIF1A DGCR8 24234451 25348397 26766590 association anti bait coimmunoprecipitation ComPPI,IntAct
HIF1A DROSHA 24234451 25348397 26766590 association anti bait coimmunoprecipitation ComPPI,IntAct
PKM HIF1A 25348397 N/A pull down,physical interaction ComPPI
CDC34 HIF1A 25348397 N/A physical interaction ComPPI
TTC1 HIF1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK3 HIF1A 25348397 N/A physical interaction ComPPI
KPNA6 HIF1A 25348397 N/A physical interaction ComPPI
SEPTIN9 HIF1A 25348397 N/A anti tag coimmunoprecipitation,physical interaction,in vitro,in vivo ComPPI
MYH1 HIF1A 25348397 N/A physical interaction ComPPI
SAT2 HIF1A 25348397 N/A physical interaction ComPPI
HIF1A HIF1A 12050673 20562859 24234451 physical association anti tag coimmunoprecipitation,surface plasmon resonance IntAct
E2F7 HIF1A 22903062 24234451 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation IntAct
HIF1A ANKRD37 23746844 24234451 association chromatin immunoprecipitation assay IntAct
HIF1A STC2 23746844 24234451 association chromatin immunoprecipitation assay IntAct
H2BC9 HIF1A 24234451 30021884 physical association cross-linking study IntAct
PRKCA HIF1A 11983697 27898060 N/A N/A OmniPath
HIF1A CTNNB1 17220880 18593917 27898060 N/A N/A OmniPath
RB1 HIF1A 15674338 27898060 stimulant N/A OmniPath
ARNTL HIF1A 25416956 27898060 9576906 9704006 N/A N/A OmniPath
MDM2 HIF1A 10640274 12606552 17234751 19696166 25447306 27898060 stimulant N/A OmniPath
HIF1A MDM2 10640274 12606552 17234751 19696166 25447306 27898060 N/A N/A OmniPath
PLK3 HIF1A 18519666 20889502 27898060 inhibition N/A OmniPath
HIF1A BNIP3 11559532 19136941 27898060 stimulant N/A OmniPath
HDAC3 HIF1A 11641274 17273746 27898060 N/A N/A OmniPath
ATM HIF1A 21095582 27898060 stimulant N/A OmniPath
HIF1A CUL2 17132228 17439941 18323857 19940151 23401859 27898060 N/A N/A OmniPath
STAT1 HIF1A 19646959 27898060 inhibition N/A OmniPath
MAPK3 HIF1A 10551817 18519666 27898060 stimulant N/A OmniPath
HIF1A TP53 10640274 11707426 12124396 12606552 16882692 27898060 9537326 stimulant N/A OmniPath
HDAC1 HIF1A 11641274 16511565 17273746 21148070 24015760 27898060 N/A N/A OmniPath
HIF1A HDAC1 11641274 16511565 17273746 21148070 24015760 27898060 N/A N/A OmniPath
CDK1 HIF1A 24189531 27898060 N/A N/A OmniPath
VHL HIF1A 10353251 10823831 10878807 10944113 10973499 11024059 11226425 11292861 11292862 11331613 11358837 11504942 11566883 11641274 11865071 11986208 12004076 12050673 12086861 12205091 12351678 12464182 12468553 12538644 12586829 12606543 12682018 12808024 12925778 14556007 14600153 14691445 15060148 15082527 15611064 15721254 15805242 16140212 16278378 16391536 16511565 16611863 17047048 17132228 17339318 17558023 17973296 17981124 17986458 18222538 18264140 18305400 18323857 18426857 18694926 18985005 19123984 19147576 19940151 20049704 20724477 21332579 21335603 21358672 21602890 22351759 22932900 23318261 23387829 23401859 23580587 24015760 24316222 24899725 25361009 25500545 26037477 26215701 26496610 26611735 26735336 27898060 inhibition N/A OmniPath
CSNK1D HIF1A 20699359 27898060 inhibition N/A OmniPath
HIF1A EGLN2 11292861 11292862 15474027 16511565 17353276 18264140 24145445 27898060 N/A N/A OmniPath
EGLN2 HIF1A 11292861 11292862 15474027 16391536 16511565 17353276 18264140 24145445 27898060 inhibition,stimulant N/A OmniPath
HIF1A AR 17011549 17426252 27898060 N/A N/A OmniPath
SP1 HIF1A 12228247 15780936 17024177 17418410 27898060 N/A N/A OmniPath
HIF1A SP1 12228247 15780936 17024177 17418410 27898060 N/A N/A OmniPath
HIF1A EGLN1 15474027 15721254 16407130 16511565 17353276 18264140 19604478 20724477 20840591 24145445 25361009 26611735 27898060 stimulant N/A OmniPath
EGLN1 HIF1A 15474027 15721254 16391536 16407130 16511565 17353276 18264140 19604478 20724477 20840591 24145445 25361009 26611735 27898060 inhibition,stimulant N/A OmniPath
EP300 HIF1A 11823643 11940656 11959990 12042299 12573436 12588875 12778114 12914934 14691445 15154850 15261140 16543236 16847340 17145710 17382325 17502379 17906695 18268343 18519678 19071119 19074848 19589782 19680224 19696166 19940151 20603618 21148070 21187066 22219185 22684029 22735262 22807441 23618863 23746844 23880760 23966271 24421387 25192544 27898060 8917528 stimulant N/A OmniPath
HIF1A EP300 11823643 11940656 11959990 12042299 12573436 12588875 12778114 12914934 14691445 15154850 15261140 16543236 16847340 17145710 17382325 17502379 17906695 18268343 18519678 19071119 19074848 19589782 19680224 19696166 19940151 20603618 21148070 21187066 22219185 22684029 22735262 22807441 23618863 23746844 23880760 23966271 24421387 25192544 27898060 8917528 N/A N/A OmniPath
MAPK1 HIF1A 10551817 18519666 27898060 stimulant N/A OmniPath
NOTCH1 HIF1A 16256737 18722525 27898060 stimulant N/A OmniPath
COPS5 HIF1A 11707426 15082527 18926707 27898060 stimulant N/A OmniPath
HIF1A EGLN3 15474027 15721254 16511565 17353276 18264140 23345396 24015760 24145445 25416956 27898060 stimulant N/A OmniPath
EGLN3 HIF1A 15474027 15721254 16391536 16511565 17353276 18264140 23345396 24015760 24145445 25416956 27898060 inhibition,stimulant N/A OmniPath
PARP1 HIF1A 18314489 27898060 stimulant N/A OmniPath
HIF1A RPTOR 17502379 27898060 N/A N/A OmniPath
SENP1 HIF1A 17981124 27898060 stimulant N/A OmniPath
HIF1A STAT3 15735682 18985005 27898060 N/A N/A OmniPath
ARNT HIF1A 11782478 11829741 15319539 15347669 16126907 20049704 20562859 20603618 20932347 21435239 21620138 26496610 27898060 8816435 8927054 9079689 9704006 N/A N/A OmniPath
HIF1A ARNT 11782478 11829741 15319539 15347669 16126907 20049704 20562859 20603618 20932347 21435239 21620138 26496610 27898060 8816435 8927054 9079689 9704006 N/A N/A OmniPath
HIF1A HIF1AN 11641274 12042299 12080085 12215170 12446723 14734545 17003112 17244529 17382325 19071119 19074848 19696166 19940151 24145445 26752685 27898060 N/A N/A OmniPath
HIF1AN HIF1A 11641274 12042299 12080085 12215170 12446723 12573436 14734545 17003112 17244529 17382325 19071119 19074848 19696166 19940151 24145445 26752685 27898060 inhibition,stimulant N/A OmniPath
HIF1A SMAD3 11486006 12228247 27898060 N/A N/A OmniPath
HIF1A HIF3A 11734856 16126907 27898060 N/A N/A OmniPath
HIF1A SEPTIN9 16424018 19934318 27898060 N/A N/A OmniPath
NAA10 HIF1A 12464182 16288748 16511565 16638120 18593917 27898060 stimulant N/A OmniPath
HIF1A NAA10 12464182 16288748 16511565 16638120 18593917 27898060 N/A N/A OmniPath
MVP HIF1A 20175781 27898060 N/A N/A OmniPath
RWDD3 HIF1A 17956732 25500545 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS0000600EEF HIF1A 14580258 14744852 15363852 23577602 27087310 9923855 direct interaction,inhibition N/A NPInter
URS0000382715 HIF1A 23577602 27087310 direct interaction,inhibition N/A NPInter
URS00009B1289 HIF1A 27087310 direct interaction,inhibition N/A NPInter
URS00009C4A90 HIF1A 27087310 direct interaction,inhibition N/A NPInter
URS000075BB37 HIF1A 12459261 28529080 direct interaction,inhibition experimental interaction detection lncRInter

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