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GENE：HMOX2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HMOX2
FullNmae heme oxygenase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5014
EnsembleID ENSG00000103415
Uniprot P30519

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HMOX2 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HMOX2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HMOX2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HMOX2 GO:0001666,GO:0004392,GO:0004392,GO:0005515,GO:0005789,GO:0005886,GO:0005886,GO:0006788,GO:0006979,GO:0016020,GO:0020037,GO:0035579,GO:0042167,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HMOX2 hsa:3163 path:hsa00860 Porphyrin metabolism - Homo sapiens (human)
HMOX2 hsa:3163 path:hsa01100 Metabolic pathways - Homo sapiens (human)
HMOX2 hsa:3163 path:hsa04978 Mineral absorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR HMOX2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 HMOX2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 HMOX2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 HMOX2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 HMOX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HMOX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 HMOX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HMOX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HMOX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 HMOX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HMOX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 HMOX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000021D7C8 HMOX2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
ATP5F1B HMOX2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LMNA HMOX2 25348397 N/A physical interaction ComPPI
LAPTM5 HMOX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SHC1 HMOX2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SETDB1 HMOX2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GIT1 HMOX2 14525934 16169070 21900206 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CANX HMOX2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PTPN1 HMOX2 25348397 N/A physical interaction ComPPI
CSNK2A1 HMOX2 14525934 14527438 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
EVC2 HMOX2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SYT1 HMOX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EIF3C HMOX2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RBBP4 HMOX2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CEBPZ HMOX2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
COPS6 HMOX2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HAP1 HMOX2 16169070 21900206 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
JADE1 HMOX2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KCNMA1 HMOX2 14525934 15528406 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
NR3C1 HMOX2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GPRASP1 HMOX2 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
VIPR2 HMOX2 25348397 N/A physical interaction ComPPI
HTR2C HMOX2 25348397 N/A physical interaction ComPPI
PTRH2 HMOX2 25348397 N/A physical interaction ComPPI
DUSP22 HMOX2 25348397 N/A physical interaction ComPPI
IMMT HMOX2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KCNJ6 HMOX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MTNR1A HMOX2 24234451 25348397 26514267 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
CD79A HMOX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIF1 HMOX2 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
GNB2 HMOX2 25348397 N/A physical interaction ComPPI
SNX5 HMOX2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BLOC1S2 HMOX2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ASIC1 HMOX2 25348397 N/A physical interaction ComPPI
EEF1G HMOX2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ALG2 HMOX2 25348397 N/A physical interaction ComPPI
HMOX2 ITFG1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HMOX2 A2M 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HMOX2 NKRF 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HMOX2 INPP5K 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HMOX2 ZNF746 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HMOX2 NDUFS2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HMOX2 SNX7 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HMOX2 POTEE 25348397 N/A physical interaction ComPPI
HMOX2 PRAF2 25348397 N/A physical interaction ComPPI
HMOX2 DUSP9 25348397 N/A physical interaction ComPPI
HMOX2 C3AR1 25348397 N/A physical interaction ComPPI
HMOX2 SAR1A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HMOX2 ELOVL5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HMOX2 APP 12057765 14525934 27898060 N/A experimental interaction detection,two hybrid HPRD,OmniPath
CCR2 HMOX2 24234451 28298427 physical association ubiquitin reconstruction IntAct
F2RL1 HMOX2 24234451 28298427 physical association ubiquitin reconstruction IntAct
PTGER4 HMOX2 24234451 28298427 physical association ubiquitin reconstruction IntAct
SMO HMOX2 24234451 28298427 physical association ubiquitin reconstruction IntAct
HMOX2 NOP56 24234451 30021884 physical association cross-linking study IntAct
HMOX2 KHSRP 24234451 30021884 physical association cross-linking study IntAct
HMOX2 DOT1L 24234451 30021884 physical association cross-linking study IntAct
HMOX2 HBA1 10490932 27898060 inhibition N/A OmniPath

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