GENE:LTF
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | LTF |
| FullNmae | lactotransferrin |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:6720 |
| EnsembleID | ENSG00000012223 |
| Uniprot | P02788 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| LTF | mpt | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| LTF | GO:0001503,GO:0001530,GO:0001817,GO:0001895,GO:0002227,GO:0003677,GO:0004252,GO:0004869,GO:0005506,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0005615,GO:0005634,GO:0005737,GO:0005769,GO:0005886,GO:0006508,GO:0006826,GO:0006959,GO:0008201,GO:0009986,GO:0019731,GO:0019731,GO:0019732,GO:0030141,GO:0031640,GO:0031640,GO:0031665,GO:0032680,GO:0032780,GO:0032991,GO:0033690,GO:0034145,GO:0034755,GO:0035580,GO:0042581,GO:0043066,GO:0043123,GO:0043539,GO:0044793,GO:0045071,GO:0045669,GO:0048525,GO:0050829,GO:0051092,GO:0055037,GO:0060349,GO:0061844,GO:0070062,GO:0071902,GO:0097013,GO:0140912,GO:1900159,GO:1900229,GO:1902732,GO:1904724,GO:2000117,GO:2000308,GO:2001205 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LTF | LY96 | 18364398 24088817 26192618 | interaction type | N/A | ACSN |
| LTF | TIRAP | 18364398 24088817 26192618 | interaction type | N/A | ACSN |
| LTF | MYD88 | 18364398 24088817 26192618 | interaction type | N/A | ACSN |
| LTF | CD14 | 11083760 18364398 23180781 24088817 26192618 | interaction type,physical association | affinity chromatography technology,biosensor | ACSN,InnateDB |
| CEBPE | LTF | 12522000 15588942 23180781 | physical association | anti tag coimmunoprecipitation,electrophoretic mobility supershift assay | InnateDB |
| LTF | CEBPD | 15588942 23180781 | physical association | electrophoretic mobility supershift assay | InnateDB |
| LTF | CEBPA | 12522000 15588942 23180781 | physical association | anti tag coimmunoprecipitation,electrophoretic mobility supershift assay | InnateDB |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CEBPA | LTF | 12522000 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| ETS1 | LTF | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | LTF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | LTF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | LTF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | LTF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | LTF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPE | LTF | 12522000 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SP1 | LTF | 10845904 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| DAND5 | LTF | 10845904 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ESR1 | LTF | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | LTF | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000160683 | LTF | 23479198 25416803 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS000043C1C3 | LTF | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000116F83 | LTF | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005194EC | LTF | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000321A1A | LTF | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CALM1 | LTF | 25348397 | N/A | physical interaction | ComPPI |
| CDK5RAP3 | LTF | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| CLU | LTF | 25348397 | N/A | physical interaction | ComPPI |
| UBC | LTF | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | LTF | 25348397 | N/A | physical interaction | ComPPI |
| WWP2 | LTF | 25348397 | N/A | physical interaction | ComPPI |
| POLL | LTF | 25348397 | N/A | physical interaction | ComPPI |
| LRP1 | LTF | 14525934 1464627 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| CFTR | LTF | 25348397 | N/A | physical interaction | ComPPI |
| LTF | CP | 10666301 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| LTF | LCN1 | 10558865 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| LTF | LYZ | 14525934 25348397 27898060 9359845 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,OmniPath |
| LTF | CD14 | 11083760 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| LTF | CEL | 25348397 27898060 3995055 | N/A | in vitro | ComPPI,OmniPath |
| LTF | MUC7 | 12766201 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| LTF | ITLN1 | 11313366 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
| LTF | SGK1 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| LTF | SIRT7 | 25348397 | N/A | physical interaction | ComPPI |
| LTF | MAPK15 | 23602568 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| LTF | CCDC148 | 25348397 | N/A | physical interaction | ComPPI |
| LTF | SIRPG | 25348397 | N/A | physical interaction | ComPPI |
| LTF | TMEM237 | 25348397 | N/A | physical interaction | ComPPI |
| LTF | FN3KRP | 25348397 | N/A | physical interaction | ComPPI |
| LTF | ICE2 | 25348397 | N/A | physical interaction | ComPPI |
| LTF | ZNF250 | 25348397 | N/A | physical interaction | ComPPI |
| LTF | EPPIN | 25348397 | N/A | physical interaction | ComPPI |
| LTF | DDX31 | 25348397 | N/A | physical interaction | ComPPI |
| LTF | SNX27 | 25348397 | N/A | physical interaction | ComPPI |
| LTF | HBM | 25348397 | N/A | physical interaction | ComPPI |
| LTF | FRMD1 | 25348397 | N/A | physical interaction | ComPPI |
| LTF | CDK15 | 25348397 | N/A | physical interaction | ComPPI |
| LTF | APCDD1 | 25348397 | N/A | physical interaction | ComPPI |
| LTF | PRAP1 | 25348397 | N/A | physical interaction | ComPPI |
| LTF | PIGA | 25348397 | N/A | physical interaction | ComPPI |
| LTF | DHX30 | 25348397 | N/A | physical interaction | ComPPI |
| LTF | CYLD | 25348397 | N/A | physical interaction | ComPPI |
| LTF | HTN3 | 25348397 | N/A | physical interaction | ComPPI |
| LTF | NCL | 21575138 24234451 25348397 27898060 | N/A | surface plasmon resonance,surface plasmon resonance array | ComPPI,IntAct,OmniPath |
| LTF | AEBP2 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| LTF | STK4 | 23386615 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |
| DDX19B | LTF | 25348397 | N/A | physical interaction | ComPPI |
| LTF | CALM2 | 14525934 1544444 | N/A | experimental interaction detection | HPRD |
| METTL3 | LTF | 24234451 29507755 | association | anti tag coimmunoprecipitation | IntAct |
| METTL14 | LTF | 24234451 29507755 | association | anti tag coimmunoprecipitation | IntAct |
| CEBPA | LTF | 10845904 27898060 | stimulant | N/A | OmniPath |
| LTF | CD14 | 11083760 27898060 | N/A | N/A | OmniPath |
| LTF | LRP11 | 14596620 1464627 27898060 | stimulant | N/A | OmniPath |
