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GENE：S100A9

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol S100A9
FullNmae S100 calcium binding protein A9
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10499
EnsembleID ENSG00000163220
Uniprot P06702

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
S100A9 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
S100A9 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
S100A9 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
S100A9 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
S100A9 GO:0002523,GO:0002523,GO:0002544,GO:0005509,GO:0005509,GO:0005515,GO:0005576,GO:0005576,GO:0005615,GO:0005615,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0005856,GO:0005886,GO:0006914,GO:0006915,GO:0006919,GO:0006954,GO:0007267,GO:0008017,GO:0008270,GO:0010976,GO:0014002,GO:0016209,GO:0018119,GO:0030307,GO:0030593,GO:0030593,GO:0032119,GO:0032496,GO:0034774,GO:0035425,GO:0035606,GO:0035662,GO:0035821,GO:0042742,GO:0043542,GO:0045087,GO:0045113,GO:0048306,GO:0050544,GO:0050729,GO:0050786,GO:0050832,GO:0051092,GO:0051493,GO:0061844,GO:0061844,GO:0062023,GO:0070062,GO:0070488,GO:0070488,GO:0098869,GO:2001244

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
S100A9 hsa:6280 path:hsa04657 IL-17 signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
S100A9 S100A8 10571075 10976885 12553726 12645005 17553524 18802069 18809714 19732719 23180781 23248262 23431180 26192618 interaction type,physical association mass spectrometry studies of complexes,pull down,x-ray crystallography ACSN,InnateDB
STAT3 S100A9 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 26192618 27216177 28186502 7543512 interaction type N/A ACSN
JUN S100A9 11001584 11274345 16054035 16396903 16406505 16880536 17000779 17439715 17638910 18754008 18813803 19081070 19190345 19219074 20107231 22354771 23031257 26192618 26587781 8545107 interaction type N/A ACSN
GLI1 S100A9 11001584 11960000 12138125 14555646 15087129 15520176 16054035 16158046 16328026 16396903 16406505 16571352 16880536 17000779 17035233 17638910 18754008 18813803 19081070 19190345 19219074 19736394 20107231 21059263 21442356 22354771 23031257 26192618 interaction type N/A ACSN
S100A9 S100A9 10976885 11851337 17553524 23180781 physical association mass spectrometry studies of complexes,x-ray crystallography InnateDB
EGFR S100A9 16799092 23180781 physical association pull down InnateDB
CEACAM3 S100A9 11708798 23180781 physical association anti tag coimmunoprecipitation InnateDB
RAC1 S100A9 15642721 23180781 physical association pull down InnateDB
RAC2 S100A9 15642721 23180781 physical association pull down InnateDB
S100A9 NCF2 15642721 23180781 physical association pull down InnateDB
LY96 S100A9 23180781 23667563 physical association affinity technology InnateDB
AGER S100A9 23180781 23667563 physical association affinity technology InnateDB
HNRNPD S100A9 23180781 26318153 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
CEBPA S100A9 18971253 9706399 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
CEBPB S100A9 9706399 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
TFAP2C S100A9 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 S100A9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF S100A9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GLI1 S100A9 16880536 trascriptional regulation,stimulation inferred by curator TFlink
AR S100A9 N/A trascriptional regulation,stimulation inferred by curator TFlink
MYB S100A9 N/A trascriptional regulation,stimulation inferred by curator TFlink
RARA S100A9 N/A trascriptional regulation,stimulation inferred by curator TFlink
RARB S100A9 N/A trascriptional regulation,stimulation inferred by curator TFlink
RARG S100A9 N/A trascriptional regulation,stimulation inferred by curator TFlink
SPI1 S100A9 N/A trascriptional regulation,stimulation inferred by curator TFlink
TP53 S100A9 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000028BB8 S100A9 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAPK14 S100A9 22135298 phosphorylation N/A PhosphoSite
S100A8 S100A9 25361965 interaction type N/A PTMCode2
S100A9 S100A8 25361965 interaction type N/A PTMCode2
PPP2R1A S100A9 25361965 interaction type N/A PTMCode2
S100A9 PPP2R1A 25361965 interaction type N/A PTMCode2
MIF S100A9 25361965 interaction type N/A PTMCode2
S100A9 MIF 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TBC1D22B S100A9 25348397 N/A physical interaction ComPPI
PDE4DIP S100A9 25348397 N/A physical interaction ComPPI
CUL5 S100A9 25348397 N/A physical interaction ComPPI
SAP18 S100A9 25348397 N/A physical interaction ComPPI
DDX21 S100A9 25348397 N/A physical interaction ComPPI
CDC42 S100A9 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
DHX15 S100A9 25348397 N/A physical interaction ComPPI
ZNRD2 S100A9 25348397 N/A physical interaction ComPPI
CD2BP2 S100A9 25348397 N/A physical interaction ComPPI
S100B S100A9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP2R1A S100A9 19156129 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAGEA1 S100A9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TUBB S100A9 25348397 N/A physical interaction ComPPI
MAGEA6 S100A9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MCM5 S100A9 25348397 N/A physical interaction ComPPI
GABARAPL2 S100A9 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NUBP2 S100A9 25348397 N/A physical interaction ComPPI
U2AF1L5 S100A9 25348397 N/A physical interaction ComPPI
RAD21 S100A9 25348397 N/A physical interaction ComPPI
KEAP1 S100A9 25348397 N/A physical interaction ComPPI
MCM2 S100A9 25348397 N/A physical interaction ComPPI
PAK5 S100A9 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NF2 S100A9 25348397 N/A physical interaction ComPPI
TLE3 S100A9 25348397 N/A physical interaction ComPPI
SHC1 S100A9 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DSTN S100A9 25348397 N/A physical interaction ComPPI
GRB2 S100A9 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
COPS5 S100A9 25348397 N/A physical interaction ComPPI
RBM39 S100A9 25348397 N/A physical interaction ComPPI
MAPK14 S100A9 25348397 N/A physical interaction ComPPI
ZIC1 S100A9 25348397 N/A physical interaction ComPPI
U2AF2 S100A9 25348397 N/A physical interaction ComPPI
GAPDH S100A9 24234451 25348397 25417112 association anti bait coimmunoprecipitation ComPPI,IntAct
NTRK1 S100A9 25348397 N/A physical interaction ComPPI
DEK S100A9 25348397 N/A physical interaction ComPPI
VTN S100A9 25348397 N/A physical interaction ComPPI
ILK S100A9 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RBM14 S100A9 25348397 N/A physical interaction ComPPI
PSMA5 S100A9 25348397 N/A physical interaction ComPPI
HNRNPU S100A9 25348397 N/A physical interaction ComPPI
TPR S100A9 25348397 N/A physical interaction ComPPI
CFTR S100A9 17110338 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TAGLN S100A9 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EWSR1 S100A9 25348397 N/A physical interaction ComPPI
USF2 S100A9 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ARRB1 S100A9 17620599 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TOPORS S100A9 25348397 N/A physical interaction ComPPI
CUL2 S100A9 25348397 N/A physical interaction ComPPI
ARRB2 S100A9 17620599 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SON S100A9 25348397 N/A physical interaction ComPPI
CPLX1 S100A9 25348397 N/A physical interaction ComPPI
EGFR S100A9 14525934 16799092 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
TUBA1A S100A9 25348397 N/A physical interaction ComPPI
SUPT16H S100A9 25348397 N/A physical interaction ComPPI
NCSTN S100A9 25348397 N/A physical interaction ComPPI
PPP2R2A S100A9 24234451 25348397 28330616 association pull down ComPPI,IntAct
TPBG S100A9 25348397 N/A physical interaction ComPPI
MAP1LC3A S100A9 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NOS2 S100A9 24234451 25348397 25417112 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
PTEN S100A9 25348397 N/A physical interaction ComPPI
SRSF11 S100A9 25348397 N/A physical interaction ComPPI
UTP14A S100A9 25348397 N/A physical interaction ComPPI
NCF2 S100A9 25348397 N/A physical interaction ComPPI
NPPA S100A9 25348397 N/A physical interaction ComPPI
TRA2B S100A9 25348397 N/A physical interaction ComPPI
SRSF3 S100A9 25348397 N/A physical interaction ComPPI
AIRE S100A9 25348397 N/A physical interaction ComPPI
TRIM25 S100A9 25348397 N/A physical interaction ComPPI
SSRP1 S100A9 25348397 N/A physical interaction ComPPI
ACIN1 S100A9 25348397 N/A physical interaction ComPPI
SRSF5 S100A9 25348397 N/A physical interaction ComPPI
NUAK1 S100A9 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SMARCA5 S100A9 25348397 N/A physical interaction ComPPI
PSMB7 S100A9 25348397 N/A physical interaction ComPPI
SRSF7 S100A9 25348397 N/A physical interaction ComPPI
TRA2A S100A9 25348397 N/A physical interaction ComPPI
RNPS1 S100A9 25348397 N/A physical interaction ComPPI
TRIM55 S100A9 25348397 N/A physical interaction ComPPI
DDX19B S100A9 25348397 N/A physical interaction ComPPI
TOP1 S100A9 25348397 N/A physical interaction ComPPI
SRSF10 S100A9 25348397 N/A physical interaction ComPPI
THRAP3 S100A9 25348397 N/A physical interaction ComPPI
GTF3C1 S100A9 25348397 N/A physical interaction ComPPI
EIF4A3 S100A9 25348397 N/A physical interaction ComPPI
TOP2B S100A9 25348397 N/A physical interaction ComPPI
SF3B6 S100A9 25348397 N/A physical interaction ComPPI
S100A8 S100A9 10571075 10976885 12553726 14525934 17553524 20936779 23431180 24234451 25348397 25417112 27898060 9867828 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid pooling approach,genetic,in vitro,two hybrid ComPPI,HPRD,IntAct,OmniPath
S100A9 ASB3 25348397 N/A physical interaction ComPPI
S100A9 PPP2R2B 19156129 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
S100A9 U2AF1 25348397 N/A physical interaction ComPPI
S100A9 SART1 25348397 N/A physical interaction ComPPI
S100A9 ZC3H18 24234451 25348397 29298432 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A9 SRRT 25348397 N/A physical interaction ComPPI
S100A9 MATR3 25348397 N/A physical interaction ComPPI
S100A9 ZNF326 25348397 N/A physical interaction ComPPI
S100A9 PSRC1 25348397 N/A physical interaction ComPPI
S100A9 PRPF8 25348397 N/A physical interaction ComPPI
S100A9 SURF4 25348397 N/A physical interaction ComPPI
S100A9 LUC7L3 25348397 N/A physical interaction ComPPI
S100A9 UNK 25348397 N/A physical interaction ComPPI
S100A9 METTL23 25348397 N/A physical interaction ComPPI
S100A9 SIRT6 25348397 N/A physical interaction ComPPI
S100A9 ZNF207 25348397 N/A physical interaction ComPPI
S100A9 PI4KA 25348397 N/A physical interaction ComPPI
S100A9 SUSD3 25348397 N/A physical interaction ComPPI
S100A9 SINHCAF 25348397 N/A physical interaction ComPPI
S100A9 CYLD 25348397 N/A physical interaction ComPPI
S100A9 G3BP1 25348397 N/A physical interaction ComPPI
S100A9 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
S100A9 MAGEA3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
S100A9 S100A9 11851337 14525934 N/A experimental interaction detection HPRD
S100A9 STAT3 22962574 24234451 association chromatin immunoprecipitation assay IntAct
MAPT S100A9 24234451 26402096 association anti bait coimmunoprecipitation IntAct
EGFR S100A9 16799092 27898060 N/A N/A OmniPath
S100A9 RAC2 15642721 27898060 N/A N/A OmniPath
S100A9 TLR4 17767165 27898060 N/A N/A OmniPath
WEE1 S100A9 2478889 27898060 N/A N/A OmniPath
S100A9 RAC1 15642721 27898060 N/A N/A OmniPath
MAPK14 S100A9 15905572 17429438 22230807 2478889 27898060 N/A N/A OmniPath

Visualization










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