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GENE：SOD1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SOD1
FullNmae superoxide dismutase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11179
EnsembleID ENSG00000142168
Uniprot P00441

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SOD1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SOD1 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SOD1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SOD1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SOD1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
SOD1 cuproptosis 36882769 Copper ions entering the cytoplasm and mitochondrial intermembrane space bind to GSH and MT or form copper-containing molecular chaperones such as SOD1 which is crucial for proper function of copper. To sustain normal cellular functions, COA6, SCO1 and SCO2 work together to mediate the transfer of copper to COX in the mitochondrial intermembrane space. chaperones
SOD1 cuproptosis 36882769 Copper chaperone for superoxide dismutase(CCS) directly interacted with and transported copper ions to superoxide dismutase 1(SOD1). regulator
SOD1 cuproptosis 38495196 Cuproptosis-related genes were manually curated, and differentially expressed cuproptosis-related genes (DECuGs) were identified.Then, the 16 DECuGs were obtained by the intersection of the 5018 DEGs and 63 cuproptosis-related genes. 63 cuproptosis-related genes
SOD1 cuproptosis 38348451 Superoxide dismutase. Involved in antioxidant defense. Dysregulation may impact cellular redox balance. CRGs in the cuproptosis pathway
SOD1 cuproptosis 36313717 The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in Table S1. Genes related to copper homeostasis pathway
SOD1 cuproptosis 36211378 Forty-three cuproptosis-related genes were selected from the review of Chang et al. (13) 43 cuproptosis-related genes in the study
SOD1 cuproptosis 36568423 Additionally, 41 cuproptosis regulators were obtained from the previous publications. cuproptosis-related genes
SOD1 cuproptosis 36505872 A total of 44 cuproptosis-related genes were extracted from known literature. cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
SOD1 GO:0000303,GO:0001541,GO:0001819,GO:0001890,GO:0001895,GO:0002262,GO:0004784,GO:0004784,GO:0005507,GO:0005507,GO:0005515,GO:0005576,GO:0005615,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005739,GO:0005758,GO:0005759,GO:0005777,GO:0005777,GO:0005777,GO:0005829,GO:0005829,GO:0005829,GO:0005886,GO:0006749,GO:0006801,GO:0006801,GO:0006879,GO:0006915,GO:0007283,GO:0007566,GO:0007566,GO:0007605,GO:0007626,GO:0008089,GO:0008090,GO:0008217,GO:0008270,GO:0008340,GO:0009408,GO:0009410,GO:0010033,GO:0010467,GO:0019226,GO:0019228,GO:0019430,GO:0019430,GO:0019430,GO:0030346,GO:0031267,GO:0031410,GO:0032287,GO:0032839,GO:0032930,GO:0032991,GO:0033081,GO:0035234,GO:0040014,GO:0042542,GO:0042554,GO:0042802,GO:0043025,GO:0043065,GO:0043085,GO:0043087,GO:0043410,GO:0043524,GO:0045471,GO:0045541,GO:0045859,GO:0046620,GO:0046716,GO:0048538,GO:0048678,GO:0050665,GO:0050665,GO:0050728,GO:0050766,GO:0051087,GO:0051093,GO:0051881,GO:0060047,GO:0060052,GO:0060087,GO:0060088,GO:0070062,GO:0072593,GO:0099610,GO:1902177,GO:1904115,GO:2000242

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SOD1 hsa:6647 path:hsa04146 Peroxisome - Homo sapiens (human)
SOD1 hsa:6647 path:hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human)
SOD1 hsa:6647 path:hsa05012 Parkinson disease - Homo sapiens (human)
SOD1 hsa:6647 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
SOD1 hsa:6647 path:hsa05016 Huntington disease - Homo sapiens (human)
SOD1 hsa:6647 path:hsa05020 Prion disease - Homo sapiens (human)
SOD1 hsa:6647 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
SOD1 hsa:6647 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SOD1 IL7R 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
SOD1 EGR1 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB
SOD1 CEBPD 20385105 23180781 physical association anti tag coimmunoprecipitation InnateDB
SOD1 UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 SOD1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SOD1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SOD1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SP1 SOD1 11724400 18608091 8921911 9867871 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay,DNase I footprinting TFlink
SMARCA4 SOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SOD1 18971253 9867871 trascriptional regulation,stimulation inferred by curator TFlink
FOS SOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPD SOD1 20385105 trascriptional regulation,stimulation inferred by curator TFlink
KLF4 SOD1 23370975 trascriptional regulation,stimulation inferred by curator TFlink
MSX2 SOD1 22824755 trascriptional regulation,stimulation inferred by curator TFlink
MYT1 SOD1 15378601 trascriptional regulation,stimulation inferred by curator TFlink
MTF1 SOD1 15378601 trascriptional regulation,stimulation inferred by curator TFlink
NFE2L2 SOD1 22493435 trascriptional regulation,stimulation inferred by curator TFlink
PPARD SOD1 18048767 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 SOD1 11724400 8921911 9867871 trascriptional regulation,stimulation inferred by curator TFlink
CEBPB SOD1 N/A trascriptional regulation,stimulation inferred by curator TFlink
JUN SOD1 N/A trascriptional regulation,stimulation inferred by curator TFlink
MYC SOD1 N/A trascriptional regulation,stimulation inferred by curator TFlink
NFIC SOD1 N/A trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 SOD1 N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A SOD1 N/A trascriptional regulation,stimulation inferred by curator TFlink
WT1 SOD1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000007F792 SOD1 18716028 21203553 rna interference,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay miRSponge
URS000007F792 SOD1 18716028 21203553 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay TarBase
URS00000451A1 SOD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000F4AC3 SOD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000034B6F5 SOD1 25416803 25816284 mrna cleavage,inhibition western blot,immunohistochemistry,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
HSPA8 SOD1 25361965 interaction type N/A PTMCode2
SOD1 HSPA8 25361965 interaction type N/A PTMCode2
SOD1 SSR4 25361965 interaction type N/A PTMCode2
SSR4 SOD1 25361965 interaction type N/A PTMCode2
SOD1 BCL2 25361965 interaction type N/A PTMCode2
BCL2 SOD1 25361965 interaction type N/A PTMCode2
SOD1 HOXB2 25361965 interaction type N/A PTMCode2
HOXB2 SOD1 25361965 interaction type N/A PTMCode2
SOD1 PIPSL 25361965 interaction type N/A PTMCode2
PIPSL SOD1 25361965 interaction type N/A PTMCode2
SOD1 PPP3CA 25361965 interaction type N/A PTMCode2
PPP3CA SOD1 25361965 interaction type N/A PTMCode2
SOD1 HECW1 25361965 interaction type N/A PTMCode2
HECW1 SOD1 25361965 interaction type N/A PTMCode2
SOD1 SOD1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIN1 SOD1 25348397 N/A physical interaction ComPPI
LGALS3 SOD1 25348397 N/A physical interaction ComPPI
CHCHD2 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
DES SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
TXN2 SOD1 25348397 N/A physical interaction ComPPI
HSPA8 SOD1 19171884 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CDC42 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EIF3H SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
BAG3 SOD1 21252941 24234451 25348397 colocalization cosedimentation through density gradient,fluorescence microscopy ComPPI,IntAct
LDHB SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
LDHA SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CRYAB SOD1 25348397 N/A physical interaction ComPPI
ANXA1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PCBP1 SOD1 25348397 N/A physical interaction ComPPI
IMPDH2 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PSMC6 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CFL1 SOD1 25348397 N/A physical interaction ComPPI
PPP2R1A SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
KIF5B SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
FABP3 SOD1 25348397 N/A physical interaction ComPPI
NUTF2 SOD1 25348397 N/A physical interaction ComPPI
PSMD14 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
VCP SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
LMNA SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
GSTP1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MCM5 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
YWHAG SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
FKBP1A SOD1 25348397 N/A physical interaction ComPPI
MCM6 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MCM2 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
OPTN SOD1 25348397 N/A physical interaction ComPPI
RAC1 SOD1 18219391 24234451 25348397 27898060 N/A pull down ComPPI,IntAct,OmniPath
HSP90AB1 SOD1 25348397 N/A physical interaction ComPPI
EIF3E SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CPSF7 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MARCHF5 SOD1 25348397 N/A physical interaction ComPPI
COX17 SOD1 25348397 N/A physical interaction ComPPI
NOP10 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RBM8A SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SND1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
DSTN SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MAP4K1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NACA SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SMAD2 SOD1 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
MYBBP1A SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
UBE2L3 SOD1 25348397 N/A physical interaction ComPPI
RHOA SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PSMD11 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NBR1 SOD1 21252941 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
KPNB1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PDIA3 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PRPH SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
YWHAB SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SCYL2 SOD1 25348397 N/A physical interaction ComPPI
ACTN4 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
GAPDH SOD1 24234451 25348397 29128334 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAZ SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PFN1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PPM1A SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SERPINH1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PDIA6 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
UBC SOD1 25348397 N/A physical interaction ComPPI
UBE2N SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PGM1 SOD1 25348397 N/A physical interaction ComPPI
ENO1 SOD1 25348397 N/A physical interaction ComPPI
RUVBL1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
COPA SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PIR SOD1 25348397 N/A physical interaction ComPPI
XRCC5 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
STIP1 SOD1 25348397 N/A physical interaction ComPPI
P4HB SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
FEN1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
HSP90B1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PRDX4 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PRDX1 SOD1 25348397 N/A physical interaction ComPPI
PSAP SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PSMA6 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PDIA4 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PEBP1 SOD1 25348397 N/A physical interaction ComPPI
PABPC4 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
GLRX SOD1 25348397 N/A physical interaction ComPPI
XRCC6 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NME1 SOD1 25348397 N/A physical interaction ComPPI
TXN SOD1 25348397 N/A physical interaction ComPPI
IQGAP1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
TPR SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
HMGB1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EIF2S1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PPP2CA SOD1 25348397 N/A physical interaction ComPPI
SQSTM1 SOD1 17296612 19765191 21252941 24234451 25348397 27898060 colocalization fluorescence microscopy ComPPI,IntAct,OmniPath
S100A11 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EWSR1 SOD1 25348397 N/A physical interaction ComPPI
AKR1B1 SOD1 25348397 N/A physical interaction ComPPI
GDI1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RAP1A SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EPRS1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RPA3 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
YWHAQ SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
TRAP1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PSMC5 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
HUWE1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RPE SOD1 25348397 N/A physical interaction ComPPI
SUMO2 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SAE1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SRI SOD1 25348397 N/A physical interaction ComPPI
FKBP1B SOD1 25348397 N/A physical interaction ComPPI
SPR SOD1 25348397 N/A physical interaction ComPPI
TPI1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SRP19 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
STXBP2 SOD1 25348397 N/A physical interaction ComPPI
ATP1A1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SPTBN1 SOD1 25348397 N/A physical interaction ComPPI
PPA1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CEP55 SOD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LMNB1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CCT7 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
BANF1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
HSPA4 SOD1 15198682 15358145 17992192 24234451 25348397 27898060 29128334 association cross-linking study,physical interaction ComPPI,IntAct,OmniPath
TRIM28 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
POLR2E SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
FUBP1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
HDAC6 SOD1 25348397 N/A physical interaction ComPPI
EIF3I SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EIF5A SOD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOSC6 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RNF19A SOD1 12145308 14525934 17157513 17666395 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
HSPA9 SOD1 25348397 N/A physical interaction ComPPI
PSMD2 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
UCHL1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
ATP6V1B1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
DNM1L SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PRDX6 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
LAMP2 SOD1 21252941 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
ATOX1 SOD1 25348397 N/A physical interaction ComPPI
BCL2 SOD1 14525934 15233914 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
AP3D1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
COMMD1 SOD1 20595380 24691167 25348397 27898060 N/A physical interaction ComPPI,OmniPath
IDH3A SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
HECW1 SOD1 25348397 N/A physical interaction ComPPI
SSR4 SOD1 25348397 N/A physical interaction ComPPI
RAB9A SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EIF1AX SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SSB SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PSMD4 SOD1 25348397 N/A physical interaction ComPPI
TIMM13 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
HIVEP1 SOD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPM1B SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PGK1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PHKA1 SOD1 25348397 N/A physical interaction ComPPI
PPIA SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
UBA1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PCMT1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
HSPE1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
FABP5 SOD1 25348397 N/A physical interaction ComPPI
TIAL1 SOD1 25348397 N/A physical interaction ComPPI
PSME2 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
ELAVL1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
DYNLT1 SOD1 25348397 N/A physical interaction ComPPI
COPG1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
KARS1 SOD1 18715867 25348397 27898060 N/A in vivo ComPPI,OmniPath
ILF2 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RAE1 SOD1 25348397 N/A physical interaction ComPPI
PSMC1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
AMFR SOD1 25348397 N/A physical interaction ComPPI
PDCD6IP SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MCM3 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MCM4 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
DNAJB1 SOD1 11457725 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PHF21A SOD1 25348397 N/A physical interaction ComPPI
STMN1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CFL2 SOD1 25348397 N/A physical interaction ComPPI
MAT2A SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
STUB1 SOD1 25348397 N/A physical interaction ComPPI
NUDC SOD1 25348397 N/A physical interaction ComPPI
EIF3D SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NAP1L4 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PRKCSH SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
GANAB SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PARK7 SOD1 24234451 24947010 25348397 29128334 association cross-linking study,physical interaction,tandem affinity purification ComPPI,IntAct
EIF3A SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PPP3CA SOD1 11513882 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
EEF2 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 HOXB2 14525934 16079151 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
SOD1 CCS 10677207 12968035 14525934 24234451 25348397 9726962 physical association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SOD1 UBE3A 25348397 N/A physical interaction ComPPI
SOD1 PRDX5 24234451 25348397 29128334 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cross-linking study,physical interaction ComPPI,IntAct
SOD1 AHCYL1 25348397 N/A physical interaction ComPPI
SOD1 NME2 25348397 N/A physical interaction ComPPI
SOD1 PLS3 25348397 N/A physical interaction ComPPI
SOD1 SOD2 25348397 N/A physical interaction ComPPI
SOD1 PRDX2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 ACY1 25348397 N/A physical interaction ComPPI
SOD1 ADK 25348397 N/A physical interaction ComPPI
SOD1 ADSL 25348397 N/A physical interaction ComPPI
SOD1 AK2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 AKR1A1 25348397 N/A physical interaction ComPPI
SOD1 AKR1B15 25348397 N/A physical interaction ComPPI
SOD1 AKR1C2 25348397 N/A physical interaction ComPPI
SOD1 ASNS 25348397 N/A physical interaction ComPPI
SOD1 C11ORF54 25348397 N/A physical interaction ComPPI
SOD1 CAT 25348397 N/A physical interaction ComPPI
SOD1 COLEC10 25348397 N/A physical interaction ComPPI
SOD1 CRIP1 25348397 N/A physical interaction ComPPI
SOD1 DBI 25348397 N/A physical interaction ComPPI
SOD1 ENO2 25348397 N/A physical interaction ComPPI
SOD1 ENO3 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 FABP5P3 25348397 N/A physical interaction ComPPI
SOD1 FABP7 25348397 N/A physical interaction ComPPI
SOD1 FKBP7 25348397 N/A physical interaction ComPPI
SOD1 GLOD4 25348397 N/A physical interaction ComPPI
SOD1 GNPDA2 25348397 N/A physical interaction ComPPI
SOD1 GOT1 25348397 N/A physical interaction ComPPI
SOD1 GPX4 25348397 N/A physical interaction ComPPI
SOD1 GSTZ1 25348397 N/A physical interaction ComPPI
SOD1 HIBCH 25348397 N/A physical interaction ComPPI
SOD1 LDHAL6A 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 LDHAL6B 25348397 N/A physical interaction ComPPI
SOD1 LDHC 25348397 N/A physical interaction ComPPI
SOD1 LGALS1 25348397 N/A physical interaction ComPPI
SOD1 MDH2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 MPI 25348397 N/A physical interaction ComPPI
SOD1 OAT 25348397 N/A physical interaction ComPPI
SOD1 PABPC3 25348397 N/A physical interaction ComPPI
SOD1 PDXK 25348397 N/A physical interaction ComPPI
SOD1 PGAM1 25348397 N/A physical interaction ComPPI
SOD1 PITPNB 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 PPIF 25348397 N/A physical interaction ComPPI
SOD1 PPIL3 25348397 N/A physical interaction ComPPI
SOD1 QDPR 25348397 N/A physical interaction ComPPI
SOD1 RGN 25348397 N/A physical interaction ComPPI
SOD1 SERPINB5 25348397 N/A physical interaction ComPPI
SOD1 CBFB 25348397 N/A physical interaction ComPPI
SOD1 DAZAP1 25348397 N/A physical interaction ComPPI
SOD1 HIBADH 25348397 N/A physical interaction ComPPI
SOD1 OXCT1 25348397 N/A physical interaction ComPPI
SOD1 SORD 25348397 N/A physical interaction ComPPI
SOD1 TAGLN2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 TANGO2 25348397 N/A physical interaction ComPPI
SOD1 TKT 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 TKTL2 25348397 N/A physical interaction ComPPI
SOD1 UBE2V1 25348397 N/A physical interaction ComPPI
SOD1 PEDS1 25348397 N/A physical interaction ComPPI
SOD1 UFC1 25348397 N/A physical interaction ComPPI
SOD1 UFM1 25348397 N/A physical interaction ComPPI
SOD1 ALB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SOD1 EIF5AL1 25348397 N/A physical interaction ComPPI
SOD1 HEXB 24234451 25348397 26496610 29128334 association anti tag coimmunoprecipitation,cross-linking study,physical interaction ComPPI,IntAct
SOD1 PRCC 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SOD1 LGMN 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SOD1 USP9X 25348397 N/A physical interaction ComPPI
SOD1 NFS1 25348397 N/A physical interaction ComPPI
SOD1 SYNE2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SOD1 ASCC1 25348397 N/A physical interaction ComPPI
SOD1 PRR12 25348397 N/A physical interaction ComPPI
SOD1 KLC2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SOD1 FAAP20 25348397 N/A physical interaction ComPPI
SOD1 MAVS 25348397 N/A physical interaction ComPPI
SOD1 BCL2L13 25348397 N/A physical interaction ComPPI
SOD1 CENPV 25348397 N/A physical interaction ComPPI
SOD1 APOL2 25348397 N/A physical interaction ComPPI
SOD1 BASP1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 H1-0 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 MARCKSL1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 TBCA 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 RPL30 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 CCT2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 APRT 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 CCT8 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 PPIAL4A 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 ALDOA 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 AHSG 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 GLO1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 RUVBL2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 PTMS 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 H1-10 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 NACA 25348397 N/A physical interaction ComPPI
SOD1 NACA4P 25348397 N/A physical interaction ComPPI
SOD1 MTPN 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 PSMB6 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 HINT1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 ACOT7 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 ETFB 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 SPIN1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 ACAT1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 DDX39B 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 PSMC2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 EEF1G 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 PFDN2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 CRYZ 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 HNRNPAB 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 TAB1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 GNB1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 CUTA 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 ALDH7A1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 UBE2M 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 VAT1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 MRPL12 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 SLC25A10 25348397 N/A physical interaction ComPPI
SOD1 MOB1B 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 CLDN17 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 EPDR1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 TPD52 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 RAB21 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 GSTK1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 PSMA2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 AARS1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 SARS1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 LMNB2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 HAGH 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 ATP6V1A 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 AASDHPPT 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 ACO2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 MTHFD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 DARS1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 API5 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 NSUN2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 NUP93 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 CCAR2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 LARS1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 MYH11 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 HRNR 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 H2AC4 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SOD1 DYNC2LI1 21252941 24234451 25348397 association,physical association pull down ComPPI,IntAct
SOD1 DCTN2 21252941 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
SOD1 LAMP1 24234451 25348397 29128334 association anti bait coimmunoprecipitation ComPPI,IntAct
SOD1 HSPD1 24234451 25348397 29128334 association anti bait coimmunoprecipitation ComPPI,IntAct
SOD1 HSP90AA5P 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
SOD1 NPEPPSL1 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
SOD1 POTEKP 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
SOD1 HSP90AB3P 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
SOD1 NME2P1 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
EEF1D SOD1 20195357 24234451 25348397 29128334 association,physical association cross-linking study,display technology,physical interaction ComPPI,IntAct
EEF1B2 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EIF4A3 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RTRAF SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
ADRM1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CKB SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MIF SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
HMGB3 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
LACTB2 SOD1 25348397 N/A physical interaction ComPPI
PMP2 SOD1 25348397 N/A physical interaction ComPPI
SOD1 TAK1 25348397 N/A physical interaction ComPPI
SOD1 SOD1 12754496 14525934 1463506 17592131 19022905 19171884 19369197 19828437 21257910 23831581 24234451 N/A biophysical,classical fluorescence spectroscopy,transmission electron microscopy,cosedimentation in solution,dynamic light scattering,experimental interaction detection,light scattering,mass spectrometry studies of complexes,molecular sieving,nuclear magnetic resonance,x-ray crystallography,comigration in sds page HPRD,IntAct
SOD1 CTNND1 24234451 30021884 physical association cross-linking study IntAct
SOD1 SACS 24234451 30021884 physical association cross-linking study IntAct
SOD1 CEP95 24234451 30021884 physical association cross-linking study IntAct
SOD1 KIAA1109 24234451 30021884 physical association cross-linking study IntAct
SOD1 PDIA2 16847061 27898060 N/A N/A OmniPath
IL7R SOD1 20167604 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009AEF48 SOD1 27087310 direct interaction,inhibition N/A NPInter

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