Gene Information gene info

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GENE：SRI

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SRI
FullNmae sorcin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11292
EnsembleID ENSG00000075142
Uniprot P30626

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SRI mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SRI GO:0001508,GO:0002020,GO:0005102,GO:0005246,GO:0005509,GO:0005509,GO:0005515,GO:0005654,GO:0005737,GO:0005789,GO:0005829,GO:0006816,GO:0006880,GO:0006942,GO:0007165,GO:0007507,GO:0007517,GO:0008016,GO:0010459,GO:0010649,GO:0010880,GO:0016020,GO:0016529,GO:0030018,GO:0030315,GO:0033017,GO:0035774,GO:0042584,GO:0044325,GO:0046982,GO:0051281,GO:0051924,GO:0055118,GO:0060315,GO:0070062,GO:0070062,GO:0086004,GO:0140297,GO:1901077,GO:1901841,GO:1901844

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL7R SRI 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
SRI STAT3 21988832 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 SRI 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 SRI 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SRI 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 SRI 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 SRI 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 SRI 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 SRI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SRI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SRI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SRI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC SRI N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C28B2 SRI 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000016E46F SRI 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C04A2 SRI 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 SRI 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002F8148 SRI 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 SRI 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000031F6C2 SRI 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PLK1 SRI 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
SSNA1 SRI 25348397 N/A physical interaction ComPPI
GCA SRI 12804766 14525934 18330356 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SMAD2 SRI 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
VAPA SRI 25348397 N/A physical interaction ComPPI
RYR2 SRI 14525934 25348397 7592856 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ENO1 SRI 25348397 N/A physical interaction ComPPI
RUVBL1 SRI 25348397 N/A physical interaction ComPPI
PIR SRI 25348397 N/A physical interaction ComPPI
SRI PSEN2 10748169 14525934 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,filter binding,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SRI ANXA11 14525934 25348397 9268363 N/A experimental interaction detection,in vitro ComPPI,HPRD
SRI CACNA1C 25348397 N/A physical interaction,in vitro ComPPI
SRI SHBG 14525934 15862967 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
SRI CALCOCO2 14525934 16189514 18330356 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
SRI ALG2 25348397 N/A physical interaction ComPPI
SRI ANXA7 14525934 25348397 9268363 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SRI NRAS 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SRI SNCA 25348397 N/A physical interaction ComPPI
SRI FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
SRI VCAM1 19738201 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
SRI ITGA4 25348397 N/A physical interaction ComPPI
SRI STAT3 18330356 21988832 24234451 25348397 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
SRI SRPK2 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
SRI HAUS2 25348397 N/A physical interaction ComPPI
SRI PDE4C 25348397 N/A physical interaction ComPPI
SRI TCF12 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SRI PRR13 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SRI C12ORF57 25348397 N/A physical interaction ComPPI
SRI MPI 25348397 N/A physical interaction ComPPI
SRI PDCD6IP 25348397 N/A physical interaction ComPPI
SRI SOD1 25348397 N/A physical interaction ComPPI
SRI TIAL1 25348397 N/A physical interaction ComPPI
SRI TKT 25348397 N/A physical interaction ComPPI
SRI ATXN3 25348397 N/A physical interaction ComPPI
SRI MYH14 25348397 N/A physical interaction ComPPI
SRI ATOH1 25348397 N/A physical interaction ComPPI
SRI MTNR1A 24234451 25348397 26514267 physical association two hybrid,physical interaction ComPPI,IntAct
SRI G3BP1 25348397 N/A physical interaction ComPPI
SRI PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SRI USHBP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CACNA1S SRI 14525934 25348397 9668070 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SRI SRI 11714909 14525934 16169070 16189514 18330356 24234451 physical association two hybrid,experimental interaction detection,two hybrid pooling approach,two hybrid HPRD,IntAct
SRI RYR1 27898060 7592856 9312152 inhibition N/A OmniPath
PLK1 SRI 24427308 27898060 N/A N/A OmniPath
IL7R SRI 20167604 27898060 N/A N/A OmniPath
SRI STAT3 18330356 21988832 27898060 N/A N/A OmniPath

Visualization










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