Gene Information gene info

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GENE：MMUT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MMUT
FullNmae methylmalonyl-CoA mutase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7526
EnsembleID ENSG00000146085
Uniprot P22033

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MMUT mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MMUT GO:0003924,GO:0004494,GO:0004494,GO:0004494,GO:0005515,GO:0005737,GO:0005737,GO:0005739,GO:0005739,GO:0005759,GO:0005759,GO:0009791,GO:0019678,GO:0031419,GO:0031419,GO:0042802,GO:0042802,GO:0042803,GO:0043547,GO:0046872,GO:0050667,GO:0072341,GO:1901290

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MMUT hsa:4594 path:hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human)
MMUT hsa:4594 path:hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human)
MMUT hsa:4594 path:hsa00640 Propanoate metabolism - Homo sapiens (human)
MMUT hsa:4594 path:hsa01100 Metabolic pathways - Homo sapiens (human)
MMUT hsa:4594 path:hsa01200 Carbon metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 MMUT 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 MMUT 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 MMUT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MMUT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MMUT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MMUT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MMUT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MMUT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MMUT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MMUT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MMUT N/A trascriptional regulation,stimulation inferred by curator TFlink
E2F2 MMUT N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 MMUT 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00003D5391 MMUT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003AA845 MMUT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB MMUT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A MMUT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 MMUT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B MMUT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000046CDA6 MMUT 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PCBD1 MMUT 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
NTRK1 MMUT 25348397 N/A physical interaction ComPPI
CYP1A1 MMUT 25348397 N/A physical interaction ComPPI
PDK1 MMUT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PARG MMUT 25348397 N/A physical interaction ComPPI
GRPEL2 MMUT 25348397 N/A physical interaction ComPPI
MMUT MMAA 14525934 16641088 20876572 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
MMUT MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MMUT ARHGEF26 25348397 N/A physical interaction ComPPI
MMUT L3HYPDH 25348397 N/A physical interaction ComPPI
MMUT OXLD1 25348397 N/A physical interaction ComPPI
MMUT BPHL 25348397 N/A physical interaction ComPPI
MMUT TMEM184A 25348397 N/A physical interaction ComPPI
MMUT CFH 25348397 N/A physical interaction ComPPI
HSCB MMUT 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
MMUT MMUT 14525934 2453061 6102092 N/A experimental interaction detection HPRD

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