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GENE：BAD

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BAD
FullNmae BCL2 associated agonist of cell death
LocusType gene with protein product
Status Approved
HGNC_id HGNC:936
EnsembleID ENSG00000002330
Uniprot Q92934

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BAD parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BAD mpt 20700721 Phosphorylation inhibits binding of Bad to Bcl-2, or BclXL, and promotes its translocation to the cytosol, thereby enabling Bcl-2 and BclXL to exert effects leading to prevention of mitochondrial permeability- transition (MPT). retulator signature
BAD autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BAD autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BAD autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
BAD apoptosis 24516599 While Bad has previously been shown to play only a minor role in promoting IR-induced apoptosis of T cells in mice, we demonstrate that Bad is essential for robust IR-induced apoptosis in zebrafish embryonic neural tissue. retulator signature
BAD apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
BAD GO:0001836,GO:0005515,GO:0005543,GO:0005739,GO:0005739,GO:0005741,GO:0005741,GO:0005829,GO:0005829,GO:0005829,GO:0006007,GO:0006915,GO:0006915,GO:0006919,GO:0008289,GO:0008625,GO:0008630,GO:0008656,GO:0008656,GO:0010508,GO:0010918,GO:0019221,GO:0019901,GO:0019901,GO:0019903,GO:0032024,GO:0033133,GO:0035774,GO:0042593,GO:0043065,GO:0043065,GO:0043065,GO:0043280,GO:0044342,GO:0045579,GO:0045582,GO:0045862,GO:0046031,GO:0046034,GO:0046902,GO:0046902,GO:0046931,GO:0050679,GO:0071260,GO:0071316,GO:0071396,GO:0071456,GO:0071456,GO:0090200,GO:0097138,GO:0097191,GO:0097191,GO:0097192,GO:0097193,GO:0097193,GO:0097202,GO:0097202,GO:1902220,GO:2000078

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
BAD hsa:572 path:hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human)
BAD hsa:572 path:hsa01522 Endocrine resistance - Homo sapiens (human)
BAD hsa:572 path:hsa01524 Platinum drug resistance - Homo sapiens (human)
BAD hsa:572 path:hsa04012 ErbB signaling pathway - Homo sapiens (human)
BAD hsa:572 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
BAD hsa:572 path:hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)
BAD hsa:572 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
BAD hsa:572 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
BAD hsa:572 path:hsa04140 Autophagy - animal - Homo sapiens (human)
BAD hsa:572 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
BAD hsa:572 path:hsa04210 Apoptosis - Homo sapiens (human)
BAD hsa:572 path:hsa04370 VEGF signaling pathway - Homo sapiens (human)
BAD hsa:572 path:hsa04510 Focal adhesion - Homo sapiens (human)
BAD hsa:572 path:hsa04722 Neurotrophin signaling pathway - Homo sapiens (human)
BAD hsa:572 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
BAD hsa:572 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)
BAD hsa:572 path:hsa05010 Alzheimer disease - Homo sapiens (human)
BAD hsa:572 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
BAD hsa:572 path:hsa05020 Prion disease - Homo sapiens (human)
BAD hsa:572 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
BAD hsa:572 path:hsa05145 Toxoplasmosis - Homo sapiens (human)
BAD hsa:572 path:hsa05152 Tuberculosis - Homo sapiens (human)
BAD hsa:572 path:hsa05160 Hepatitis C - Homo sapiens (human)
BAD hsa:572 path:hsa05161 Hepatitis B - Homo sapiens (human)
BAD hsa:572 path:hsa05162 Measles - Homo sapiens (human)
BAD hsa:572 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
BAD hsa:572 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
BAD hsa:572 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
BAD hsa:572 path:hsa05200 Pathways in cancer - Homo sapiens (human)
BAD hsa:572 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)
BAD hsa:572 path:hsa05207 Chemical carcinogenesis - receptor activation - Homo sapiens (human)
BAD hsa:572 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
BAD hsa:572 path:hsa05210 Colorectal cancer - Homo sapiens (human)
BAD hsa:572 path:hsa05211 Renal cell carcinoma - Homo sapiens (human)
BAD hsa:572 path:hsa05212 Pancreatic cancer - Homo sapiens (human)
BAD hsa:572 path:hsa05213 Endometrial cancer - Homo sapiens (human)
BAD hsa:572 path:hsa05215 Prostate cancer - Homo sapiens (human)
BAD hsa:572 path:hsa05218 Melanoma - Homo sapiens (human)
BAD hsa:572 path:hsa05220 Chronic myeloid leukemia - Homo sapiens (human)
BAD hsa:572 path:hsa05221 Acute myeloid leukemia - Homo sapiens (human)
BAD hsa:572 path:hsa05223 Non-small cell lung cancer - Homo sapiens (human)
BAD hsa:572 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
BAD hsa:572 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BAD WASF1 10531306 10760476 10826997 10949026 11078441 11342610 12107820 12175651 12444011 12767520 12931191 16931767 19030972 19641503 20399103 21540285 22039431 26192618 7130182 9346240 interaction type N/A ACSN
BCL2 BAD 10826997 10949026 11342610 11704864 12107820 12175651 12444011 12767520 15849194 16931767 17446862 19030972 19641503 21540285 22039431 23064052 23180781 23377657 23430059 23850759 26192618 8929532 9346240 association,physical association gst pull down ACSN,InnateDB
PRKCQ BAD 10652356 15214048 15536066 16606694 17544292 17548359 18784374 19201850 23077238 23433459 23474202 23886063 25960930 26192618 interaction type N/A ACSN
RAF1 BAD 11532940 12107820 12566895 14764585 15516985 15849194 19289794 19565474 23180781 24027568 26192618 8929532 9069260 interaction type,phosphorylation reaction protein kinase assay ACSN,InnateDB
AKT1 BAD 10722653 10949026 11715018 11756412 11923280 15169778 15808505 15998799 16697215 17052453 17680028 18372248 18570873 18636226 20138985 20214616 20398329 20832730 23180781 26192618 9812896 interaction type,phosphorylation reaction protein kinase assay ACSN,InnateDB
CDK1 BAD 12049737 14551205 15279786 17303408 17660363 18414028 18590585 21725609 26192618 7575488 interaction type N/A ACSN
PAK1 BAD 10230394 10461188 10467124 10511705 10558990 10559936 10611223 10613909 10661401 10837486 11018042 11062502 11121431 11340065 11385609 11413130 11493700 11907067 11950587 12054568 12885870 12954615 14749719 14764585 15157156 15229651 15280015 15536084 15713627 16293614 16702231 17270021 17522712 22154077 23109003 26192618 8625410 8929531 9346240 9381178 9843499 interaction type,inhibition N/A ACSN,SignaLink
PPP3CB BAD 10089876 11796223 14741051 15036616 17593948 18235236 19136967 19608982 2550447 26192618 7650486 9973469 interaction type N/A ACSN
PPP3R1 BAD 10195903 26192618 7593193 interaction type N/A ACSN
GZMB BAD 10364179 10805722 11062502 11085742 11085743 11287608 11583622 11832478 14499263 15536084 15607806 15637055 15713684 16106370 18287025 20189481 24248158 24795729 26192618 8432729 9727492 interaction type N/A ACSN
BAD PAK1 10611223 23180781 phosphorylation reaction protein kinase assay InnateDB
BAD BCL2L1 18628207 23109003 23180781 25416956 7834748 9305851 inhibition,physical association anti tag coimmunoprecipitation,two hybrid InnateDB,SignaLink
BCL2L1 BAD 22705850 23180781 physical association anti tag coimmunoprecipitation InnateDB
TP53 BAD 23180781 24525822 physical association anti tag coimmunoprecipitation InnateDB
BAD BAD 15694340 17000778 26467481 bind,up-regulates activity,down-regulates activity,relocalization reaction N/A Signor
AKT3 BAD 15023346 23109003 inhibition N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 BAD 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
NR3C1 BAD 17496926 trascriptional regulation,stimulation inferred by curator TFlink
PPARG BAD 14960510 trascriptional regulation,stimulation inferred by curator TFlink
RELA BAD 20596645 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000007A060 BAD 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
RAF1 BAD 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PRKCQ BAD 22135298 phosphorylation N/A PhosphoSite
PRKACA BAD 22135298 phosphorylation N/A PhosphoSite
MAPK3 BAD 22135298 phosphorylation N/A PhosphoSite
PRKCI BAD 22135298 phosphorylation N/A PhosphoSite
CDK1 BAD 22135298 phosphorylation N/A PhosphoSite
PRKD1 BAD 22135298 phosphorylation N/A PhosphoSite
ARAF BAD 22135298 phosphorylation N/A PhosphoSite
PIM3 BAD 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
MAPK1 BAD 22135298 phosphorylation N/A PhosphoSite
RPS6KA1 BAD 22135298 phosphorylation N/A PhosphoSite
PRKCE BAD 22135298 phosphorylation N/A PhosphoSite
PAK1 BAD 22135298 phosphorylation N/A PhosphoSite
PIM1 BAD 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
BRAF BAD 22135298 phosphorylation N/A PhosphoSite
AKT1 BAD 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
RPS6KA3 BAD 22135298 phosphorylation N/A PhosphoSite
YWHAG BAD 25361965 interaction type N/A PTMCode2
BAD YWHAG 25361965 interaction type N/A PTMCode2
BCL2L1 BAD 25361965 interaction type N/A PTMCode2
BAD BCL2L1 25361965 interaction type N/A PTMCode2
BAD RAF1 25361965 interaction type N/A PTMCode2
BAD YWHAB 25361965 interaction type N/A PTMCode2
YWHAB BAD 25361965 interaction type N/A PTMCode2
BAD PPP1CA 25361965 interaction type N/A PTMCode2
PPP1CA BAD 25361965 interaction type N/A PTMCode2
BAD BCL2 25361965 interaction type N/A PTMCode2
BCL2 BAD 25361965 interaction type N/A PTMCode2
BAD SNCA 25361965 interaction type N/A PTMCode2
SNCA BAD 25361965 interaction type N/A PTMCode2
BAD SFN 25361965 interaction type N/A PTMCode2
SFN BAD 25361965 interaction type N/A PTMCode2
BAD BCL2L11 25361965 interaction type N/A PTMCode2
BCL2L11 BAD 25361965 interaction type N/A PTMCode2
BAD WASF1 25361965 interaction type N/A PTMCode2
WASF1 BAD 25361965 interaction type N/A PTMCode2
BAD MAPK10 25361965 interaction type N/A PTMCode2
MAPK10 BAD 25361965 interaction type N/A PTMCode2
BAD PIM3 25361965 interaction type N/A PTMCode2
BAD MCL1 25361965 interaction type N/A PTMCode2
MCL1 BAD 25361965 interaction type N/A PTMCode2
BAD PIM1 25361965 interaction type N/A PTMCode2
BAD PIM2 25361965 interaction type N/A PTMCode2
PIM2 BAD 25361965 interaction type N/A PTMCode2
BAD RPS6KA2 25361965 interaction type N/A PTMCode2
RPS6KA2 BAD 25361965 interaction type N/A PTMCode2
BAD BNIP3L 25361965 interaction type N/A PTMCode2
BNIP3L BAD 25361965 interaction type N/A PTMCode2
BAD PPP3CA 25361965 interaction type N/A PTMCode2
PPP3CA BAD 25361965 interaction type N/A PTMCode2
MAP2K5 BAD 25361965 interaction type N/A PTMCode2
BAD MAP2K5 25361965 interaction type N/A PTMCode2
BAD AKT1 25361965 interaction type N/A PTMCode2
BCL2A1 BAD 25361965 interaction type N/A PTMCode2
BAD BCL2A1 25361965 interaction type N/A PTMCode2
YWHAH BAD 25361965 interaction type N/A PTMCode2
BAD YWHAH 25361965 interaction type N/A PTMCode2
YWHAQ BAD 25361965 interaction type N/A PTMCode2
BAD YWHAQ 25361965 interaction type N/A PTMCode2
BCL2L2 BAD 25361965 interaction type N/A PTMCode2
BAD BCL2L2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIM2 BAD 12954615 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
BCL2L11 BAD 19427863 24234451 25348397 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDKN1A BAD 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
VCP BAD 25348397 N/A physical interaction ComPPI
YWHAG BAD 10880354 14525934 20936779 24234451 25348397 physical association experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro ComPPI,HPRD,IntAct
BCL2L2 BAD 11483855 12115603 14525934 15694340 22000515 24234451 25348397 physical association experimental interaction detection,isothermal titration calorimetry,surface plasmon resonance,physical interaction,two hybrid array,in vitro,in vivo,surface plasmon resonance array,two hybrid prey pooling approach ComPPI,HPRD,IntAct
KEAP1 BAD 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRT31 BAD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BCL2L1 BAD 11483855 11494146 11583631 14525934 15131699 16697956 19427857 21988832 24234451 25241761 25348397 25416956 26871637 29997244 7834748 9305851 9388232 physical association anti bait coimmunoprecipitation,bioluminescence resonance energy transfer,two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,two hybrid array,in vitro,in vivo,luminescence based mammalian interactome mapping,proximity ligation assay,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
BAD BCL2A1 10381646 11483855 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
BAD YWHAH 14525934 17979178 21988832 24234451 25348397 9369453 association,physical association two hybrid,physical interaction,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
BAD YWHAZ 11410287 11526496 14525934 19667065 21988832 23397142 24234451 25348397 colocalization,association,physical association two hybrid,coimmunoprecipitation,experimental interaction detection,surface plasmon resonance,physical interaction,in vitro,confocal microscopy,proximity ligation assay,surface plasmon resonance array,two hybrid ComPPI,HPRD,IntAct
BAD YWHAB 14525934 21900206 24234451 24255178 25348397 9369453 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
BAD PRKACA 10837486 10880354 10949026 12931191 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
BAD RPS6KA1 10521512 10837486 10880354 10949026 12897128 14525934 25348397 9381178 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
BAD RPS6KA2 25348397 N/A in vitro,in vivo ComPPI
BAD S100A10 14525934 25348397 9369453 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
BAD HRK 11483855 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
BAD YWHAE 14525934 20936779 21988832 24234451 25348397 9369453 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
BAD BCL2L10 11278245 14525934 25348397 9878060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
BAD PAK5 10521512 10837486 10880354 12897128 14525934 25348397 9381178 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
BAD MCL1 10579309 10837489 11483855 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
BAD PPP1CA 10811615 14525934 17274640 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
BAD PPP3CA 10195903 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
BAD RPS6KA5 10880354 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
BAD EWSR1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
BAD SFN 14525934 16189514 20005908 20179209 21988832 24234451 25348397 association,physical association two hybrid,coimmunoprecipitation,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
BAD RPS6KA3 11544290 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
BAD RAF1 14525934 23397142 24234451 25241761 25348397 8929531 8929532 physical association experimental interaction detection,physical interaction,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
BAD MAPK8 14525934 14967141 23397142 24234451 25348397 physical association experimental interaction detection,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
BAD PAK1 25348397 N/A physical interaction,in vitro ComPPI
BAD MAP2K5 25348397 N/A in vitro,in vivo ComPPI
BAD PIM1 14525934 16403219 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
BAD PIM3 14525934 16403219 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
BAD BCL2 11483855 14525934 15694340 16697956 17446862 19168699 24234451 25348397 7834748 9388232 9463381 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,surface plasmon resonance,physical interaction,enzyme linked immunosorbent assay,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
BAD SNCA 10407019 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
BAD AKT1 14525934 24234451 25241761 25348397 9381178 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
BAD SUMO2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BAD BAX 19427863 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BAD BRAF 25348397 N/A physical interaction ComPPI
BAD ARAF 25348397 N/A physical interaction ComPPI
BAD CREB3L3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BAD PRDX2 21988832 24234451 25348397 colocalization,physical association two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
BAD STEAP3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BAD GIMAP5 25348397 N/A physical interaction ComPPI
BAD PRKD1 25348397 N/A physical interaction ComPPI
BAD PRKCE 25348397 N/A physical interaction ComPPI
BAD NDUFA12 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAD LIMK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAD SORT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAD SYNCRIP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAD APTX 25348397 N/A physical interaction ComPPI
BAD HNRNPL 25348397 N/A physical interaction ComPPI
BAD BNIP3L 24234451 25348397 9973195 N/A pull down ComPPI,IntAct
BAD GRB2 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
BAD NAF1 20010695 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
BAD WNK1 20936779 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
BAD ACTN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CBY1 BAD 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
WASF1 BAD 12931191 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
YWHAQ BAD 14525934 21988832 24234451 25348397 8929531 9369453 colocalization,physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,confocal microscopy,two hybrid ComPPI,HPRD,IntAct
PRKCI BAD 25348397 N/A physical interaction ComPPI
PPP3CA BAD 10195903 22820751 27898060 stimulant N/A OmniPath
PRKACA BAD 10230394 10837486 10851172 10880354 10949026 11500364 12931191 18669648 18707149 18794113 19667065 20166139 27898060 inhibition,stimulant N/A OmniPath
PRKCE BAD 20179209 27898060 inhibition N/A OmniPath
PRKD1 BAD 20179209 27898060 inhibition N/A OmniPath
BCL2L1 BAD 10620799 10949026 11077446 11206074 11483855 11494146 11583631 12115603 12137781 15131699 15694340 15705582 15721256 16697956 18628207 19427857 19667065 20603619 21988832 22705850 25241761 25416956 26186194 27898060 7834748 9305851 9388232 9389483 9824152 inhibition,stimulant N/A OmniPath
BAD BCL2L1 10620799 10949026 11077446 11206074 11483855 11494146 11583631 12115603 12137781 15131699 15694340 15705582 15721256 16697956 18628207 19427857 19667065 20603619 21988832 22705850 25241761 25416956 26186194 27898060 7834748 8929531 9305851 9372935 9388232 9389483 9824152 inhibition,stimulant N/A OmniPath
GZMB BAD 11287608 27898060 stimulant N/A OmniPath
CASP3 BAD 15231831 27898060 stimulant N/A OmniPath
BCL2 BAD 11483855 15694340 15849194 15990872 16697956 17446862 19168699 20603619 27898060 7834748 9305851 9388232 9463381 inhibition N/A OmniPath
BAD BCL2 11483855 11583631 15694340 15849194 15990872 16697956 17446862 19168699 20603619 27898060 7834748 9305851 9388232 9463381 inhibition,stimulant N/A OmniPath
RPS6KA1 BAD 10521512 10558990 10837486 10880354 10949026 10976111 12897128 18039929 18246127 18669648 18707149 20166139 27898060 9381178 inhibition N/A OmniPath
PIM1 BAD 10611223 10837486 10949026 10976111 11085518 11577096 11825565 12566304 12970779 14678993 14729617 15037618 15105836 15121878 15226424 15695406 15705582 15972258 16109716 16403219 16540661 16818649 17535812 17670745 18669648 18707149 19147983 19154409 19483729 19664994 19667065 20166139 20179209 21187157 21262926 21419810 21849418 22096607 24909179 26366732 26387536 27898060 9381178 9651683 inhibition N/A OmniPath
ATM BAD 10558990 11020382 11577096 15037618 16044149 27898060 N/A N/A OmniPath
AKT1 BAD 10358075 10383455 10521512 10837486 10880354 10926925 10949026 11254732 11500364 11714830 11994280 12897128 14737178 15722337 15784622 15998799 16341064 18220336 18669648 18707149 19664994 19667065 19690332 20166139 23085457 25241761 27898060 9346240 9381178 9651683 inhibition N/A OmniPath
BAK1 BAD 27898060 9388232 inhibition N/A OmniPath
PPM1A BAD 12590938 27898060 stimulant N/A OmniPath
MAPK3 BAD 19777442 27898060 inhibition N/A OmniPath
BAD CYCS 15725726 27898060 stimulant N/A OmniPath
BAD TP53 17000778 27898060 stimulant N/A OmniPath
MCL1 BAD 10579309 10837489 11483855 11571294 15694340 27898060 inhibition,stimulant N/A OmniPath
PPP1CB BAD 22820751 27898060 N/A N/A OmniPath
RAF1 BAD 10826997 12107820 12175651 12444011 12767520 15849194 16931767 17535812 19030972 19667065 21540285 23397142 25241761 27898060 8929531 8929532 inhibition,stimulant N/A OmniPath
BAD RAF1 10826997 12107820 12175651 12444011 12767520 15849194 16931767 19030972 19667065 21540285 23397142 25241761 27898060 8929531 8929532 N/A N/A OmniPath
BAD BCL2L2 10381646 11483855 12115603 15694340 16697956 20603619 22000515 27898060 inhibition N/A OmniPath
PRKACG BAD 10230396 10949026 27898060 inhibition,stimulant N/A OmniPath
PPP5C BAD 22820751 27898060 N/A N/A OmniPath
PPP1CA BAD 10811615 17274640 22820751 27898060 stimulant N/A OmniPath
RPS6KA3 BAD 10558990 10976111 11544290 11983683 19282669 27898060 inhibition N/A OmniPath
MAPK1 BAD 27898060 8929531 inhibition N/A OmniPath
PAK1 BAD 10195903 10230394 10558990 10611223 10837486 10949026 11493700 12531792 12954615 14678993 15037618 15226424 15280015 15784622 15849194 15972258 16413544 17270021 18669648 18707149 19667065 20166139 21317286 22096607 27898060 8929531 9346240 9381178 inhibition N/A OmniPath
AKT3 BAD 10949026 27898060 inhibition,stimulant N/A OmniPath
PRKCI BAD 15705582 21419810 27898060 inhibition N/A OmniPath
PPP2CA BAD 12944463 22820751 27898060 N/A N/A OmniPath
BAX BAD 27898060 9388232 inhibition N/A OmniPath
RPS6KA2 BAD 10521512 10558990 10837486 10880354 10949026 12897128 18669648 18707149 19282669 20166139 27898060 9381178 inhibition,stimulant N/A OmniPath
AKT2 BAD 10949026 27898060 inhibition,stimulant N/A OmniPath
PPP2R5C BAD 11222372 27898060 stimulant N/A OmniPath
MAPK8 BAD 14967141 15526032 15725726 23397142 27898060 inhibition,stimulant N/A OmniPath
IKBKB BAD 23332762 27898060 inhibition N/A OmniPath
PPM1B BAD 22820751 27898060 N/A N/A OmniPath
ALPL BAD 22820751 27898060 N/A N/A OmniPath
PIM2 BAD 10837473 10837486 10949026 12954615 16403219 18669648 18707149 19664994 20166139 27898060 9381178 9651683 inhibition N/A OmniPath
PPP3CB BAD 10195903 22820751 27898060 stimulant N/A OmniPath
PRKACB BAD 10949026 27898060 inhibition,stimulant N/A OmniPath
PPP1CC BAD 22820751 27898060 N/A N/A OmniPath
YWHAH BAD 11697890 21988832 27898060 8929531 9369453 inhibition N/A OmniPath
PPP3CC BAD 10195903 22820751 27898060 stimulant N/A OmniPath
PIM3 BAD 10837486 10949026 16403219 18669648 18707149 19664994 20166139 27898060 9381178 9651683 inhibition N/A OmniPath
PPP2CB BAD 12944463 22820751 27898060 N/A N/A OmniPath
PAK5 BAD 10521512 10837486 10880354 12897128 27898060 9381178 N/A N/A OmniPath

Visualization










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