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GENE：ABCG2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ABCG2
FullNmae ATP binding cassette subfamily G member 2 (JR blood group)
LocusType gene with protein product
Status Approved
HGNC_id HGNC:74
EnsembleID ENSG00000118777
Uniprot Q9UNQ0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ABCG2 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ABCG2 GO:0005515,GO:0005524,GO:0005654,GO:0005886,GO:0005886,GO:0005886,GO:0006869,GO:0008514,GO:0008559,GO:0015143,GO:0015143,GO:0015225,GO:0015562,GO:0015562,GO:0015562,GO:0015711,GO:0015747,GO:0015878,GO:0016324,GO:0016324,GO:0016887,GO:0031526,GO:0031966,GO:0032217,GO:0032217,GO:0032218,GO:0042626,GO:0042626,GO:0042802,GO:0042803,GO:0042910,GO:0045121,GO:0046415,GO:0055085,GO:0055085,GO:0070633,GO:0097744,GO:0098591,GO:0140115,GO:0150104,GO:1990748,GO:1990962,GO:1990962

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ABCG2 hsa:9429 path:hsa01523 Antifolate resistance - Homo sapiens (human)
ABCG2 hsa:9429 path:hsa02010 ABC transporters - Homo sapiens (human)
ABCG2 hsa:9429 path:hsa04976 Bile secretion - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ABCG2 GLI1 21625222 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR ABCG2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 ABCG2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ABCG2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ABCG2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ABCG2 18234970 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ABCG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ABCG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ABCG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ABCG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ABCG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A ABCG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ABCG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
AHR ABCG2 20460431 trascriptional regulation,stimulation inferred by curator TFlink
ESR1 ABCG2 10342828 trascriptional regulation,stimulation inferred by curator TFlink
MSX2 ABCG2 21465479 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 ABCG2 10342828 trascriptional regulation,stimulation inferred by curator TFlink
PGR ABCG2 22348324 trascriptional regulation,stimulation inferred by curator TFlink
PPARG ABCG2 16785230 trascriptional regulation,stimulation inferred by curator TFlink
RELA ABCG2 10342828 trascriptional regulation,stimulation inferred by curator TFlink
SP1 ABCG2 21465479 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 ABCG2 21465479 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005FDE70 ABCG2 19270061 \N rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000037D7E5 ABCG2 18573883 19825807 \N rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00005FDE70 ABCG2 18927107 19270061 21219875 22453125 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS000037D7E5 ABCG2 18573883 18927107 19825807 21219875 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS00000B59A2 ABCG2 16822819 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 ABCG2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000016D2D4 ABCG2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001E0AEA ABCG2 23619912 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS000016FD1B ABCG2 23879965 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001EFEC1 ABCG2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB ABCG2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000045B99E ABCG2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000006DA05 ABCG2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D ABCG2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000017EE98 ABCG2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002A71AD ABCG2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA ABCG2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000DD591 ABCG2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 ABCG2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A ABCG2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000153377 ABCG2 25416803 26517090 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS00001AFC71 ABCG2 25416803 25766675 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00003CF1AD ABCG2 25416803 28008607 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
PIM1 ABCG2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
ABCG2 PIM1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIM1 ABCG2 25348397 N/A two hybrid ComPPI
RAB7A ABCG2 25348397 N/A physical interaction ComPPI
UBC ABCG2 19909340 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation ComPPI,IntAct,OmniPath
PHF12 ABCG2 25348397 N/A physical interaction ComPPI
SYNPO ABCG2 25348397 N/A physical interaction ComPPI
PCDH7 ABCG2 25348397 N/A physical interaction ComPPI
DBN1 ABCG2 25348397 N/A physical interaction ComPPI
MYO5C ABCG2 25348397 N/A physical interaction ComPPI
GOLT1B ABCG2 25348397 N/A physical interaction ComPPI
ABCG2 ABCG2 16870176 17098188 19506252 20399185 24234451 physical association anti tag coimmunoprecipitation,electron microscopy,blue native page,comigration in non denaturing gel electrophoresis,electron tomography IntAct
PIM1 ABCG2 18056989 27898060 N/A N/A OmniPath

Visualization










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