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GENE：EIF2AK2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EIF2AK2
FullNmae eukaryotic translation initiation factor 2 alpha kinase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9437
EnsembleID ENSG00000055332
Uniprot P19525

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EIF2AK2 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EIF2AK2 necroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
EIF2AK2 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EIF2AK2 GO:0001819,GO:0003723,GO:0003725,GO:0004672,GO:0004672,GO:0004674,GO:0004694,GO:0004694,GO:0004715,GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0005840,GO:0006412,GO:0006468,GO:0006468,GO:0008285,GO:0009615,GO:0016020,GO:0016301,GO:0017148,GO:0017148,GO:0019888,GO:0030968,GO:0032722,GO:0032874,GO:0033689,GO:0034198,GO:0035455,GO:0042802,GO:0043066,GO:0043410,GO:0045071,GO:0046777,GO:0046777,GO:0048471,GO:0051092,GO:0051607,GO:0106310,GO:0140374,GO:1900225,GO:1901224,GO:1901532,GO:1902033,GO:1902036

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EIF2AK2 hsa:5610 path:hsa04217 Necroptosis - Homo sapiens (human)
EIF2AK2 hsa:5610 path:hsa05010 Alzheimer disease - Homo sapiens (human)
EIF2AK2 hsa:5610 path:hsa05160 Hepatitis C - Homo sapiens (human)
EIF2AK2 hsa:5610 path:hsa05162 Measles - Homo sapiens (human)
EIF2AK2 hsa:5610 path:hsa05164 Influenza A - Homo sapiens (human)
EIF2AK2 hsa:5610 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
EIF2AK2 hsa:5610 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
EIF2AK2 hsa:5610 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
EIF2AK2 hsa:5610 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
EIF2AK2 hsa:5610 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
EIF2AK2 hsa:5610 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IKBKB EIF2AK2 16600570 23180781 physical association gst pull down InnateDB
EIF2AK2 TIRAP 11526399 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 MAP3K7 12609980 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 CHUK 10723127 23180781 physical association anti tag coimmunoprecipitation InnateDB
STAT2 EIF2AK2 12954221 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
EIF2AK2 SP3 12954221 23180781 physical association affinity chromatography technology,electrophoretic mobility supershift assay InnateDB
SP1 EIF2AK2 12954221 23180781 physical association affinity chromatography technology,electrophoretic mobility supershift assay InnateDB
EIF2AK2 STAT1 12954221 21178011 23180781 23597922 phosphorylation reaction,stimulation,physical association affinity chromatography technology,anti tag coimmunoprecipitation InnateDB,SignaLink
EIF2AK2 DHX9 19229320 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
DHX58 EIF2AK2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 HNRNPC 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 KCTD17 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 LYAR 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 NOP2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 DICER1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 TOLLIP 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 STAU2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 FARSA 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 DHX30 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 CCNA2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 IFRD1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 TARBP2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 EDC4 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 CCDC124 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 GNL3 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 GTPBP4 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 PURA 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 PPP1CC 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 XRN2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 ZNF346 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 NOP53 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 FTSJ3 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 H1-2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 SSB 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 TOP1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 PRKRA 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 STAU1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 FARSB 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 NOC3L 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 HNRNPCL1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 PABPC4 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 EBNA1BP2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 MOV10 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 EIF6 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 CDK3 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
TYK2 EIF2AK2 23180781 23236554 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 JAK1 23180781 23236554 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 IRF9 21178011 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 STAT2 21178011 23180781 physical association anti tag coimmunoprecipitation InnateDB
ISG15 EIF2AK2 16009940 23180781 physical association unspecified method InnateDB

Source Target Pmid Interactiontype Methods Database
DBNL EIF2AK2 20005715 interaction type N/A PSP
TAB2 EIF2AK2 20005715 interaction type N/A PSP
NFKBIA EIF2AK2 20005715 interaction type N/A PSP
PPP2R5A EIF2AK2 20005715 interaction type N/A PSP
TAB2 EIF2AK2 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR EIF2AK2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 EIF2AK2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 EIF2AK2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 EIF2AK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EIF2AK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EIF2AK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 EIF2AK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
IRF1 EIF2AK2 8622878 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 EIF2AK2 20584986 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS0000070B1D EIF2AK2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000041CB9C EIF2AK2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CF056 EIF2AK2 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00003D8730 EIF2AK2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000170D8B EIF2AK2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 EIF2AK2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 EIF2AK2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A EIF2AK2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 EIF2AK2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 EIF2AK2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 EIF2AK2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 EIF2AK2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C EIF2AK2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD EIF2AK2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D EIF2AK2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED EIF2AK2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 EIF2AK2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001A4ABF EIF2AK2 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EIF2AK2 EIF2AK2 22135298 phosphorylation N/A PhosphoSite
EIF2AK2 EIF2S1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
EIF2AK2 CDK1 22135298 phosphorylation N/A PhosphoSite
EIF2AK2 PPP2R5A 22135298 phosphorylation N/A PhosphoSite
EIF2AK2 TP53 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
MAPK14 EIF2AK2 22135298 phosphorylation N/A PhosphoSite
MAPK1 EIF2AK2 22135298 phosphorylation N/A PhosphoSite
RPS6KA3 EIF2AK2 22135298 phosphorylation N/A PhosphoSite
EIF2AK1 EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 EIF2AK1 25361965 interaction type N/A PTMCode2
EIF2S1 EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 STAT3 25361965 interaction type N/A PTMCode2
STAT3 EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 TYK2 25361965 interaction type N/A PTMCode2
TYK2 EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 ELF2 25361965 interaction type N/A PTMCode2
ELF2 EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 TARBP2 25361965 interaction type N/A PTMCode2
TARBP2 EIF2AK2 25361965 interaction type N/A PTMCode2
TP53 EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 NPM1 25361965 interaction type N/A PTMCode2
NPM1 EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 CASP3 25361965 interaction type N/A PTMCode2
CASP3 EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 PRKRA 25361965 interaction type N/A PTMCode2
PRKRA EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 PPP1CA 25361965 interaction type N/A PTMCode2
PPP1CA EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 HSP90AA1 25361965 interaction type N/A PTMCode2
HSP90AA1 EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 JAK1 25361965 interaction type N/A PTMCode2
JAK1 EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 CASP8 25361965 interaction type N/A PTMCode2
CASP8 EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 ILF2 25361965 interaction type N/A PTMCode2
ILF2 EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 CHUK 25361965 interaction type N/A PTMCode2
CHUK EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 DNAJC3 25361965 interaction type N/A PTMCode2
DNAJC3 EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 TIRAP 25361965 interaction type N/A PTMCode2
TIRAP EIF2AK2 25361965 interaction type N/A PTMCode2
EIF2AK2 ILF3 25361965 interaction type N/A PTMCode2
ILF3 EIF2AK2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HNRNPC EIF2AK2 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC42 EIF2AK2 14525934 24234451 25348397 7738010 N/A experimental interaction detection,pull down,in vitro ComPPI,HPRD,IntAct
GPX7 EIF2AK2 25348397 N/A physical interaction ComPPI
PPP1CC EIF2AK2 12138106 14525934 21903422 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
ISG15 EIF2AK2 25348397 N/A physical interaction ComPPI
NPM1 EIF2AK2 12882984 14525934 16957780 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,imaging technique,in vitro,in vivo ComPPI,HPRD,IntAct
STAT1 EIF2AK2 11278865 14525934 25348397 9135145 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TRAF6 EIF2AK2 25348397 N/A physical interaction ComPPI
LMNA EIF2AK2 25348397 N/A physical interaction ComPPI
GABARAPL2 EIF2AK2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TYK2 EIF2AK2 14525934 17290288 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MCM2 EIF2AK2 25348397 N/A physical interaction ComPPI
RAC1 EIF2AK2 14525934 25348397 7738010 N/A experimental interaction detection,in vitro ComPPI,HPRD
HSP90AB1 EIF2AK2 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
AIM2 EIF2AK2 22801494 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL10 EIF2AK2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CASP3 EIF2AK2 11555640 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
JUN EIF2AK2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
DHX9 EIF2AK2 19229320 21903422 24234451 25348397 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
CUL3 EIF2AK2 25348397 N/A physical interaction ComPPI
PDGFRB EIF2AK2 11350938 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
DLD EIF2AK2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
HSP90AA1 EIF2AK2 11447118 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
NTRK1 EIF2AK2 25348397 N/A physical interaction ComPPI
JAK1 EIF2AK2 14525934 17290288 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
EIF2AK2 PPP2R5A 10866685 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
EIF2AK2 CASP7 11555640 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
EIF2AK2 CASP8 11555640 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
EIF2AK2 METAP2 11123929 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EIF2AK2 MAP3K5 12473108 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EIF2AK2 IKBKB 10848580 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EIF2AK2 TARBP2 10330179 11438532 14525934 21903422 24234451 25348397 7568151 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
EIF2AK2 TIRAP 25348397 N/A in vivo ComPPI
EIF2AK2 PTGES3 11447118 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EIF2AK2 THAP12 14525934 25348397 8576172 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
EIF2AK2 STRBP 10684936 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
EIF2AK2 PRKRIP1 12679338 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EIF2AK2 PPP1CA 12138106 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EIF2AK2 STAT3 11350938 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
EIF2AK2 PRKRA 11238927 11985496 14525934 21903422 23455922 24234451 25348397 9687506 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,nuclear magnetic resonance,pull down,physical interaction,two hybrid array,in vitro,in vivo,tandem affinity purification,two hybrid prey pooling approach ComPPI,HPRD,IntAct
EIF2AK2 CHUK 10648614 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
EIF2AK2 ILF3 10320367 10400669 10684936 11438536 11438540 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
EIF2AK2 MAP3K7 12609980 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
EIF2AK2 TAB2 12609980 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
EIF2AK2 EIF2S1 10542257 11985496 14525934 16288713 1677563 18971339 24234451 25348397 8099444 9431994 9819435 phosphorylation reaction,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,phosphorylation reaction,physical interaction,competition binding,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
EIF2AK2 ELF2 14525934 17290288 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
EIF2AK2 HSPA1A 12397061 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
EIF2AK2 HSPA1B 25348397 N/A in vivo ComPPI
EIF2AK2 DBNL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 FANCC 25348397 N/A physical interaction ComPPI
EIF2AK2 TP53 10348343 10747897 10884347 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
EIF2AK2 DNAJC3 14525934 25348397 8576172 N/A experimental interaction detection,physical interaction ComPPI,HPRD
EIF2AK2 H2AC20 25348397 N/A physical interaction ComPPI
EIF2AK2 DHX58 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 CCNA2 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 DICER1 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 EDC4 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 STAU2 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 ZNF346 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 STAU1 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 CCDC124 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 CDK3 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 FARSB 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 FTSJ3 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 NOP53 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 IFRD1 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 NOC3L 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 DHX30 21903422 23455922 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
EIF2AK2 EIF6 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 FARSA 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 GNL3 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 GTPBP4 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 H1-2 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 HNRNPCL1 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 KCTD17 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 MOV10 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 NOP2 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 PABPC4 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 PURA 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 SSB 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 TOLLIP 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 TOP1 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 XRN2 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 MAVS 25348397 N/A physical interaction ComPPI
EIF2AK2 HDGF 25348397 N/A physical interaction ComPPI
EIF2AK2 ELAVL1 25348397 N/A physical interaction ComPPI
EIF2AK2 CAND1 25348397 N/A physical interaction ComPPI
EIF2AK2 ATP6V1F 25348397 N/A physical interaction ComPPI
EIF2AK2 HSP90AA2P 25348397 N/A physical interaction ComPPI
EIF2AK2 IL7R 25348397 N/A physical interaction ComPPI
EIF2AK2 EIF2A 25348397 N/A physical interaction ComPPI
EIF2AK2 HECW2 25348397 N/A physical interaction ComPPI
EIF2AK2 IGF2BP3 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
EIF2AK2 IGF2BP2 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
EIF2AK2 EGFR 25348397 N/A physical interaction ComPPI
EIF2AK2 TRAF5 25348397 N/A physical interaction ComPPI
EIF2AK2 TRAF2 25348397 N/A physical interaction ComPPI
EIF2AK2 CYP1A1 25348397 N/A physical interaction ComPPI
EIF2AK2 IFI16 25348397 N/A physical interaction ComPPI
EIF2AK2 SCARB2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 MIDEAS 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 CDCA5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 CHMP4B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 MACROD1 25348397 N/A physical interaction ComPPI
EIF2AK2 CDC37 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
EIF2AK2 H2AC4 25348397 N/A physical interaction ComPPI
EIF2AK2 MECP2 25348397 N/A physical interaction ComPPI
EIF2AK2 IQCF1 25348397 N/A physical interaction ComPPI
EIF2AK2 PTEN 25348397 N/A physical interaction ComPPI
EIF2AK2 RPL6 25348397 N/A physical interaction ComPPI
EIF2AK2 RPLP0 25348397 N/A physical interaction ComPPI
EIF2AK2 RPLP0P6 25348397 N/A physical interaction ComPPI
EIF2AK2 RPS2 25348397 N/A physical interaction ComPPI
EIF2AK2 RPS3A 25348397 N/A physical interaction ComPPI
EIF2AK2 COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EIF2AK2 DLST 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EIF2AK2 NLRP3 22801494 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
EIF2AK2 NLRP1 22801494 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 NLRC4 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
EIF2AK2 CDK1 20395957 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
EIF2AK2 RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NFKBIA EIF2AK2 10723127 14525934 25348397 8601309 9214631 9721103 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ILF2 EIF2AK2 25348397 N/A physical interaction ComPPI
LYAR EIF2AK2 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EBNA1BP2 EIF2AK2 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2AK2 EIF2AK2 11337501 14525934 16373505 24234451 8887659 9528799 phosphorylation reaction experimental interaction detection,far western blotting,protein kinase assay HPRD,IntAct
EIF2AK2 EIF2S1 10542257 11432733 11985496 15550948 16179258 16179259 16288713 1677563 17290288 19364808 21368187 27898060 2912723 8096514 8099444 9335428 9431994 9819435 inhibition,stimulant N/A OmniPath
MAP3K7 EIF2AK2 12609980 27898060 N/A N/A OmniPath
CHUK EIF2AK2 10648614 10723127 10848580 27898060 N/A N/A OmniPath
CASP7 EIF2AK2 11555640 27898060 N/A N/A OmniPath
CASP3 EIF2AK2 11555640 27898060 N/A N/A OmniPath
FANCC EIF2AK2 12397061 15299030 18266962 27898060 inhibition N/A OmniPath
EIF2AK2 STAT1 10637230 11278865 21178011 27898060 9135145 inhibition,stimulant N/A OmniPath
EIF2AK2 JAK1 17290288 23236554 27898060 N/A N/A OmniPath
JAK1 EIF2AK2 17290288 23236554 27898060 N/A N/A OmniPath
EIF2AK2 TYK2 17290288 23236554 27898060 N/A N/A OmniPath
EIF2AK2 TP53 10082513 10348343 10747897 10884347 19413330 27898060 9737981 stimulant N/A OmniPath
CASP8 EIF2AK2 11555640 27898060 N/A N/A OmniPath
EIF2AK2 NFKBIA 10723127 27898060 8601309 9214631 9721103 N/A N/A OmniPath
EIF2AK2 CDK1 20395957 27898060 inhibition N/A OmniPath
PPP1CA EIF2AK2 12138106 27898060 N/A N/A OmniPath
RPS6KA3 EIF2AK2 11337501 15880455 17404396 27898060 stimulant N/A OmniPath
MAPK1 EIF2AK2 27898060 9528799 stimulant N/A OmniPath
ISG15 EIF2AK2 16009940 27898060 N/A N/A OmniPath
PRKRA EIF2AK2 10988289 11238927 11985496 12368348 16785445 21903422 23455922 24778252 27898060 9687506 stimulant N/A OmniPath
EIF2AK2 CAMK2A 16126727 20060891 27898060 N/A N/A OmniPath
TIRAP EIF2AK2 11526399 27898060 N/A N/A OmniPath
IKBKB EIF2AK2 10848580 16600570 27898060 stimulant N/A OmniPath
DNAJC3 EIF2AK2 25329545 27898060 8576172 9447982 inhibition N/A OmniPath
DHX58 EIF2AK2 21903422 27898060 N/A N/A OmniPath
EIF2AK2 TOLLIP 21903422 27898060 N/A N/A OmniPath
EIF2AK2 PPP2R5A 10866685 18957415 27898060 stimulant N/A OmniPath

Visualization










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