GENE：HJV
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | HJV |
| FullNmae | hemojuvelin BMP co-receptor |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:4887 |
| EnsembleID | ENSG00000168509 |
| Uniprot | Q6ZVN8 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| HJV | mpt | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| HJV | GO:0000122,GO:0005102,GO:0005515,GO:0005615,GO:0005886,GO:0005886,GO:0006366,GO:0006879,GO:0009986,GO:0015026,GO:0015026,GO:0016540,GO:0030509,GO:0030509,GO:0030509,GO:0030514,GO:0032924,GO:0036122,GO:0045944,GO:0045944,GO:0060586,GO:0060586,GO:0070724,GO:0071773,GO:0098552,GO:0098797,GO:0098821,GO:1990459,GO:1990712 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| HJV | hsa:148738 | path:hsa04350 | TGF-beta signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | HJV | 18971253 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | HJV | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | HJV | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | HJV | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | HJV | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | HJV | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | HJV | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | HJV | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | HJV | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | HJV | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | HJV | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | HJV | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| BMP2 | HJV | 18335997 24234451 25348397 | physical association | surface plasmon resonance,x-ray crystallography,physical interaction,surface plasmon resonance array | ComPPI,IntAct |
| TMPRSS6 | HJV | 20704562 24234451 25348397 | physical association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| NEO1 | HJV | 18335997 24234451 25348397 | N/A | pull down,static light scattering,surface plasmon resonance,surface plasmon resonance array | ComPPI,IntAct |
| BMP6 | HJV | 19252486 27898060 | N/A | N/A | OmniPath |
| BMP2 | HJV | 18287331 25938661 27898060 | N/A | N/A | OmniPath |