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GENE：BMF

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BMF
FullNmae Bcl2 modifying factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24132
EnsembleID ENSG00000104081
Uniprot Q96LC9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BMF mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BMF autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BMF autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
BMF apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BMF apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
BMF anoikis 21673109 BCL-2 modifying factor (BMF) is a central regulator of anoikis in human intestinal epithelial cells. retulator signature

Go Annotation:

GeneSymbol Go id
BMF GO:0005515,GO:0005741,GO:0005829,GO:0005886,GO:0010507,GO:0010507,GO:0016459,GO:0016459,GO:0031334,GO:0034644,GO:0043065,GO:0043065,GO:0043276,GO:0090200

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
BMF hsa:90427 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MCL1 BMF 11546872 23850759 26192618 association N/A ACSN
BCL2 BMF 11546872 11704864 17446862 22039431 23064052 23377657 23430059 23850759 26192618 8929532 association N/A ACSN
BMF MAPK8 12591950 23180781 phosphorylation reaction in-gel kinase assay InnateDB
BMF EGR1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB
BCL2A1 BMF 23180781 25416956 physical association two hybrid InnateDB
BCL2L2 BMF 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR BMF 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 BMF 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 BMF 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 BMF 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 BMF 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 BMF 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 BMF 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 BMF 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 BMF 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 BMF 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 BMF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA BMF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF BMF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 BMF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 BMF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 BMF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS BMF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A BMF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF BMF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 BMF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 BMF 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000170CF4 BMF 19671867 \N rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000170CF4 BMF 19671867 20388802 22743998 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRDeathDB,TarBase
URS00002C7B2B BMF 22370637 25416803 mrna cleavage,inhibition experimental interaction detection,rna immunoprecipitation,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000F4AC3 BMF 24488097 25416803 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000153377 BMF 25416803 26370254 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
MAPK1 BMF 22135298 phosphorylation N/A PhosphoSite
MAPK8 BMF 22135298 phosphorylation N/A PhosphoSite
BCL2 BMF 25361965 interaction type N/A PTMCode2
BMF BCL2 25361965 interaction type N/A PTMCode2
BMF MAPK10 25361965 interaction type N/A PTMCode2
MAPK10 BMF 25361965 interaction type N/A PTMCode2
BMF MCL1 25361965 interaction type N/A PTMCode2
MCL1 BMF 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GPSM3 BMF 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DYNLL1 BMF 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DYNLL2 BMF 11546872 14525934 14561217 24234451 25348397 25416956 physical association experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
BAG3 BMF 25348397 N/A physical interaction ComPPI
CXCL9 BMF 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BCL2L2 BMF 11546872 14525934 24234451 25348397 25416956 physical association experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
BCL2L1 BMF 14525934 15694340 16697956 24234451 25348397 25416956 26871637 physical association experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
REL BMF 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAPK8 BMF 12591950 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MCL1 BMF 11546872 14525934 16697956 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
AQP1 BMF 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BCL2A1 BMF 25348397 N/A physical interaction ComPPI
SHC3 BMF 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BCL2 BMF 11546872 14525934 16697956 17289999 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
TFIP11 BMF 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TCF12 BMF 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BMF MYO5A 25348397 N/A physical interaction ComPPI
BMF NNMT 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BMF SEC14L4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BMF LCN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BMF CTAG1A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BMF BCL2L1 11546872 15694340 15721256 16260615 16697956 25416956 27898060 inhibition N/A OmniPath
BMF BCL2 11546872 16697956 17289999 27898060 inhibition N/A OmniPath
DYNLL2 BMF 11546872 12209154 14561217 20889982 25416956 27898060 inhibition N/A OmniPath
BMF MCL1 11546872 15694340 15721256 16697956 27898060 inhibition N/A OmniPath
BMF BCL2L2 11546872 25416956 27898060 inhibition,stimulant N/A OmniPath
MAPK1 BMF 22258404 27898060 stimulant N/A OmniPath
MAPK8 BMF 12591950 18222916 27898060 stimulant N/A OmniPath

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