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GENE：HADHB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HADHB
FullNmae hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4803
EnsembleID ENSG00000138029
Uniprot P55084

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HADHB mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HADHB GO:0003723,GO:0003857,GO:0003985,GO:0003988,GO:0004300,GO:0005515,GO:0005739,GO:0005739,GO:0005739,GO:0005740,GO:0005741,GO:0005743,GO:0005743,GO:0005783,GO:0006635,GO:0006635,GO:0006635,GO:0010467,GO:0016507,GO:0042645,GO:0050633,GO:0071222,GO:0106222

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HADHB hsa:3032 path:hsa00062 Fatty acid elongation - Homo sapiens (human)
HADHB hsa:3032 path:hsa00071 Fatty acid degradation - Homo sapiens (human)
HADHB hsa:3032 path:hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human)
HADHB hsa:3032 path:hsa01100 Metabolic pathways - Homo sapiens (human)
HADHB hsa:3032 path:hsa01212 Fatty acid metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CDK2 HADHB 21319273 23180781 physical association anti tag coimmunoprecipitation InnateDB
ADRB2 HADHB 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 HADHB 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 HADHB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 HADHB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HADHB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HADHB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 HADHB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 HADHB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HADHB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HADHB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 HADHB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC HADHB N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 HADHB 21512034 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000157026 HADHB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000CBE63 HADHB 25416803 27199118 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000006FDD4 HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000122F23 HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000519450 HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 HADHB 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HADHB HADHA 25361965 interaction type N/A PTMCode2
HADHA HADHB 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DES HADHB 25348397 N/A physical interaction ComPPI
RELL2 HADHB 25348397 N/A physical interaction ComPPI
CDKN1A HADHB 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TK1 HADHB 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FASTKD3 HADHB 20869947 24234451 25348397 association tandem affinity purification ComPPI,IntAct
GABARAPL2 HADHB 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KEAP1 HADHB 25348397 N/A physical interaction ComPPI
MCM2 HADHB 25348397 N/A physical interaction ComPPI
MAP1LC3B HADHB 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMN1 HADHB 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HSP90AB1 HADHB 25348397 N/A physical interaction ComPPI
SYNDIG1 HADHB 25348397 N/A physical interaction ComPPI
COX17 HADHB 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CD44 HADHB 25348397 N/A physical interaction ComPPI
GRB7 HADHB 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPP1R15A HADHB 24234451 25348397 29109149 association anti tag coimmunoprecipitation ComPPI,IntAct
GRB2 HADHB 12577067 24234451 25348397 association pull down ComPPI,IntAct
JUN HADHB 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
PSMA3 HADHB 25348397 N/A physical interaction ComPPI
SDC2 HADHB 25348397 N/A physical interaction ComPPI
GSK3B HADHB 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
KPNB1 HADHB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PEX19 HADHB 25348397 N/A physical interaction ComPPI
TUBG1 HADHB 25348397 N/A physical interaction ComPPI
UBC HADHB 25348397 N/A physical interaction ComPPI
NTRK1 HADHB 25348397 N/A physical interaction ComPPI
CANX HADHB 24234451 25348397 29568061 association pull down ComPPI,IntAct
CDH5 HADHB 25348397 N/A physical interaction ComPPI
YBX1 HADHB 22118625 24234451 25348397 association tandem affinity purification ComPPI,IntAct
PPP1CA HADHB 24234451 25348397 25593058 association anti bait coimmunoprecipitation ComPPI,IntAct
MYC HADHB 17314511 21150319 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
VDAC1 HADHB 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SQSTM1 HADHB 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GRK5 HADHB 25348397 N/A physical interaction ComPPI
RCC1 HADHB 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RPS6 HADHB 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HUWE1 HADHB 25348397 N/A physical interaction ComPPI
CSNK2A2 HADHB 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ATP1A1 HADHB 25348397 N/A physical interaction ComPPI
ATP1B1 HADHB 25348397 N/A physical interaction ComPPI
CDK2 HADHB 25348397 N/A physical interaction ComPPI
ADRB2 HADHB 25348397 N/A physical interaction ComPPI
EGFR HADHB 25348397 N/A physical interaction ComPPI
MED23 HADHB 25348397 N/A physical interaction ComPPI
GABARAP HADHB 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MAP1LC3A HADHB 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RIPK2 HADHB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
UQCRC2 HADHB 25348397 N/A physical interaction ComPPI
GPC1 HADHB 25348397 N/A physical interaction ComPPI
PRKN HADHB 25348397 N/A physical interaction ComPPI
CUL7 HADHB 25348397 N/A physical interaction ComPPI
NFKB2 HADHB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TNNI3K HADHB 12721663 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SKI HADHB 25348397 N/A physical interaction ComPPI
AURKAIP1 HADHB 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
IQCB1 HADHB 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NES HADHB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB1 HADHB 25348397 N/A physical interaction ComPPI
PAN2 HADHB 25348397 N/A physical interaction ComPPI
ATF2 HADHB 22304920 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IGSF8 HADHB 25348397 N/A physical interaction ComPPI
CDH8 HADHB 25348397 N/A physical interaction ComPPI
MED4 HADHB 25348397 N/A physical interaction ComPPI
HSPD1 HADHB 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HSD17B10 HADHB 25348397 N/A physical interaction ComPPI
CYLD HADHB 25348397 N/A physical interaction ComPPI
GABARAPL1 HADHB 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
LEO1 HADHB 25348397 N/A physical interaction ComPPI
FBXO6 HADHB 25348397 N/A physical interaction ComPPI
MAP3K1 HADHB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
HADHB ATG101 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HADHB ANXA7 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HADHB RTF1 25348397 N/A physical interaction ComPPI
HADHB HADHA 25348397 N/A physical interaction ComPPI
HADHB RPS8 25348397 N/A physical interaction ComPPI
HADHB OPA1 25348397 N/A physical interaction ComPPI
HADHB SUOX 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HADHB TIMM8B 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HADHB CHCHD4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HADHB PPP6R1 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HADHB TP53 25348397 N/A physical interaction ComPPI
HADHB LRRC46 25348397 N/A physical interaction ComPPI
HADHB SLC39A4 25348397 N/A physical interaction ComPPI
HADHB TMEFF1 25348397 N/A physical interaction ComPPI
HADHB KCNA6 25348397 N/A physical interaction ComPPI
HADHB DDOST 25348397 N/A physical interaction ComPPI
HADHB HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HADHB NAF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HADHB ZNF746 25348397 N/A physical interaction ComPPI
HADHB PTPRD 25348397 N/A physical interaction ComPPI
HADHB C17ORF80 25348397 N/A physical interaction ComPPI
HADHB YBEY 25348397 N/A physical interaction ComPPI
HADHB POTEI 25348397 N/A physical interaction ComPPI
HADHB MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
HADHB MEX3C 22863774 24234451 25348397 association pull down ComPPI,IntAct
HADHB RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
HADHB DUX1 24234451 25348397 26816005 physical association two hybrid ComPPI,IntAct
HADHB PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
DDA1 HADHB 25348397 N/A physical interaction ComPPI
HADHB APP 11430884 14525934 27898060 N/A experimental interaction detection HPRD,OmniPath
MKI67 HADHB 24234451 26949251 association anti tag coimmunoprecipitation IntAct
HADHB ELOA 24234451 30021884 physical association cross-linking study IntAct
HADHB CCL11 24234451 30021884 physical association cross-linking study IntAct
HADHB NEMF 24234451 30021884 physical association cross-linking study IntAct

Visualization










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